Human Toxicology of Chemical Mixtures

Produk Detail:
  • Author : Harold Zeliger
  • Publisher : William Andrew
  • Pages : 574 pages
  • ISBN : 9781437734645
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Human Toxicology of Chemical Mixtures

Download or Read online Human Toxicology of Chemical Mixtures full in PDF, ePub and kindle. this book written by Harold Zeliger and published by William Andrew which was released on 24 June 2011 with total page 574 pages. We cannot guarantee that Human Toxicology of Chemical Mixtures book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author’s focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are explained, as well as the body’s methods of defending itself against xenobiotic intrusion. Part II examines the sources of the chemicals discusssed, looking at air and water pollution, food additives, pharmaceuticals, etc. Part III, which includes numerous case studies, examines specific effects of particular mixtures on particular body systems and organs and presents a theoretical framework for predicting what the effects of uncharacterized mixtures might be. Part IV covers regulatory requirements and the need to adjust recommended exposure levels for products containing mixtures. It also contains recommendations on how to limit exposure to mixtures in the products we use and on how to limit release of mixtures into the environment. Providing brief summaries of each mixture and its effects, Zeliger provides a comprehensive reference, a jumping off point for professionals (with extensive chapter bibliographies) and an introduction to the topic for those studying traditional toxicology. Addressing many inadequately understood illnesses and conditions such as asthma, infertility and cancer, it will also be of interest to health professionals, environmental scientists and lawyers. Presents a theoretical framework for predicting the effects of chemical mixtures for which no specific data exists (this predictive aspect is important due to the vast number of different potential chemical combinations - far too many to comprehensively catalog) A quick and convenient source of hard to come by data on the rapidly developing field of chemical mixtures, for groups including chemists and engineers, toxicologists, health professionals and environmental scientists New and updated material comprises over 30% of this timely new edition, which includes the latest research data alongside an expanded introduction to the science and art of predicting the toxicological properties of chemical mixtures

Human Toxicology of Chemical Mixtures

Human Toxicology of Chemical Mixtures
  • Author : Harold Zeliger
  • Publisher : William Andrew
  • Release : 24 June 2011
GET THIS BOOK Human Toxicology of Chemical Mixtures

In this important reference work, Zeliger catalogs the known effects of chemical mixtures on the human body and also proposes a framework for understanding and predicting their actions in terms of lipophile (fat soluble) / hydrophile (water soluble) interactions. The author’s focus is on illnesses that ensue following exposures to mixtures of chemicals that cannot be attributed to any one component of the mixture. In the first part the mechanisms of chemical absorption at a molecular and macromolecular level are

Mixture Toxicity

Mixture Toxicity
  • Author : Cornelis A. M. van Gestel,Martijs Jonker,Jan E. Kammenga,Ryszard Laskowski,Claus Svendsen
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOK Mixture Toxicity

In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology and classic human toxicology, Mixture Toxicity: Linking Approaches from Ecological and Human Toxicology incorporates extensive reviews of exposure to toxicants, toxicokinetics and toxicodynamics, toxicity of mixtures, and

Toxicology of Chemical Mixtures

Toxicology of Chemical Mixtures
  • Author : Raymond S.H. Yang
  • Publisher : Elsevier
  • Release : 14 May 2016
GET THIS BOOK Toxicology of Chemical Mixtures

Although toxicologic studies in the laboratory often focus on a single chemical, in the larger world, mixtures of chemicals are routinely encountered. Toxicology of Chemical Mixtures examines the mechanisms of interactions and health effects stemming from chemical mixtures in the environment. Toxicologists, pharmacologists, environmental scientists, and professionals involved in environmental clean-ups will benefit from its content. Emphasis is on low-level, long-term exposure. Key Features * Some of the issues addressed include: * Target organ toxicities in response to chemical mixture exposures * Risk

The Toxicology of Chemical Mixtures Risk Assessment for Human and Ecological Receptors

The Toxicology of Chemical Mixtures Risk Assessment for Human and Ecological Receptors
  • Author : Anonim
  • Publisher : Unknown
  • Release : 02 July 2022
GET THIS BOOK The Toxicology of Chemical Mixtures Risk Assessment for Human and Ecological Receptors

Mixtures of chemicals represent a concern in all areas of toxicology and a challenge to risk assessors as most sites with environmental contamination, including Department of Defense sites, involve simultaneous or sequential exposures of multiple chemicals to human or ecological receptors. A major concern with mixtures is that they may lead to outcomes (health effects) or increased toxicity (synergism) not expected from the risk characterization of individual chemicals at the site. The focus of this literature review is 0 examine the

Genetic Toxicology of Complex Mixtures

Genetic Toxicology of Complex Mixtures
  • Author : Michael D. Waters,F.Bernhard Daniel,Joellen Lewtas,Martha M. Moore,Stephen Nesnow
  • Publisher : Springer Science & Business Media
  • Release : 13 March 2013
GET THIS BOOK Genetic Toxicology of Complex Mixtures

Contained in this volume are the proceedings of the international conference on the "Genetic Toxicology of Complex Mixtures," held from July 4-7, 1989, in Washington, DC. This meeting was a satellite of the "Fifth International Conference on Environmental Mutagens" and the seventh in a biennial series of conferences on "Short-term Bioassays in the Analysis of Complex Environmental Mixtures. " Our central objective in calling together key researchers from around the world was to extend our knowledge of the application of the methods

Chemical Mixtures and Combined Chemical and Nonchemical Stressors

Chemical Mixtures and Combined Chemical and Nonchemical Stressors
  • Author : Cynthia V. Rider,Jane Ellen Simmons
  • Publisher : Springer
  • Release : 16 February 2018
GET THIS BOOK Chemical Mixtures and Combined Chemical and Nonchemical Stressors

In this book, both basic and advanced concepts are discussed for considering mixtures from initial exposure characterization through evaluation of risk associated with combined exposures. This book will provide an introduction to key issues and multiple options for evaluating both the toxicity of mixtures as well as the risk associated with exposure to mixtures. Additionally, promising tools adapted from other disciplines will be discussed in the context of mixtures toxicology and risk assessment. Finally, the discussion will move beyond chemical

Toxicology of Chemical Mixtures Experimental Approaches Underlying Concepts and Some Results

Toxicology of Chemical Mixtures  Experimental Approaches  Underlying Concepts  and Some Results
  • Author : Raymond S. Yang,H. L. Long,Gary A. Boorman,NATIONAL INST OF ENVIRONMENTAL HEALTH SCIENCES RESEARCH TRIANGLE PARK NC.
  • Publisher : Unknown
  • Release : 02 July 1990
GET THIS BOOK Toxicology of Chemical Mixtures Experimental Approaches Underlying Concepts and Some Results

The toxicology of chemical mixtures will be the toxicology of the 1990s and beyond. While this branch of toxicology most closely reflects the actual human exposure situation, as yet, there is no standard protocol or consensus methodology for investigating the toxicology of mixtures. Thus, in this emerging science, experimentation is required just to develop a broadly applicable evaluation system. Several examples are discussed to illustrate the different experimental designs and the concepts behind each. These include the health effects studies

A Pound of Prevention for a Healthier Life

A Pound of Prevention for a Healthier Life
  • Author : Harold I. Zeliger
  • Publisher : Universal-Publishers
  • Release : 15 April 2019
GET THIS BOOK A Pound of Prevention for a Healthier Life

A Pound of Prevention for a Healthier Life shows the connection between oxidative stress and the onset of virtually all disease and discusses the causes of oxidative stress induced disease and ways to prevent it. The book includes a unique questionnaire for predicting disease onset in seemingly healthy people, and shows how steps taken to prevent any one disease may prevent many other unrelated diseases. Dr. Harold I. Zeliger, a chemical toxicologist who has been researching the causes of non-communicable

Principles and Practice of Mixtures Toxicology

Principles and Practice of Mixtures Toxicology
  • Author : Moiz Mumtaz
  • Publisher : John Wiley & Sons
  • Release : 23 May 2011
GET THIS BOOK Principles and Practice of Mixtures Toxicology

This first comprehensive treatment of the subject for more than a decade includes the latest research on nanoparticle toxicology. The practical handbook addresses all areas where toxic mixtures are encountered, from environmental via occupational to medical settings, giving special consideration to air and water, and to the specific requirements for study design in mixture toxicology. While no extensive prior knowledge or toxicological experience is required, the practice-oriented case studies and examples in the second part make this the ideal companion

Toxicological Risk Assessment of Chemicals

Toxicological Risk Assessment of Chemicals
  • Author : Elsa Nielsen,Grete Ostergaard,John Christian Larsen
  • Publisher : CRC Press
  • Release : 21 February 2008
GET THIS BOOK Toxicological Risk Assessment of Chemicals

Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk assessment of chemical substances. It illustrates each step in the process: hazard identification, a dose response assessment, and exposure assessment. The book also summarizes the basic concepts of interaction of chemicals

Oxidative Stress

Oxidative Stress
  • Author : Harold Zeliger
  • Publisher : Academic Press
  • Release : 01 September 2022
GET THIS BOOK Oxidative Stress

Oxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation. Sections cover the causes and prevention of oxidative stress, the types of chemical exposures and environmental factors that precipitate disease, disease hallmarks and biomarkers, disease clusters, disease co-morbidities, free radical attacks at the cellular level, and the Oxidative Stress Index tool, its premise, and how it can be used to identify the primary causes

Diversification in Toxicology Man and Environment

Diversification in Toxicology     Man and Environment
  • Author : Jürg P. Seiler,Judith L. Autrup,Herman Autrup
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOK Diversification in Toxicology Man and Environment

This volume contains the main papers presented at the 1997 EUROTOX Congress, Århus, Denmark, 24-28 June 1997. Diversification in toxicology is seen as the application of basic science to such diverse areas as man and his environment. The pressing issues which have been dealt with not only include reproductive effects of environmental chemicals ("xenoestrogens"), but also receptor-mediated toxic responses, new frontiers in human and ecological toxicology, chemoprevention of cancer and molecular approaches in toxicological research. The practical and ethical facets of toxicology,

Current Issues on Chemical Mixtures and Model Validation Concepts and Their Application to Lead Models

Current Issues on Chemical Mixtures and Model Validation Concepts and Their Application to Lead Models
  • Author : Raymond S. H. Yang,William A. Suk
  • Publisher : Unknown
  • Release : 01 October 2002
GET THIS BOOK Current Issues on Chemical Mixtures and Model Validation Concepts and Their Application to Lead Models

Papers include: human health and chemical mixtures: an overview; public health challenges posed by chemical mixtures; toxicology of chemical mixtures: international perspective; maximum workplace concentration values and carcinogenicity classification for mixtures; 14 papers on biomedical and methodological advances on chemical mixtures; 6 papers on ecological engineering advances on chemical mixtures; and 16 papers on model validation concepts and their application to lead models.