Heart Development And Regeneration

✏Book Title : Heart Development and Regeneration
✏Author : Nadia Rosenthal
✏Publisher : Academic Press
✏Release Date : 2010-05-28
✏Pages : 1136
✏ISBN : 9780123813336
✏Available Language : English, Spanish, And French

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✏Heart Development and Regeneration Book Summary : The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. Authored by world experts in heart development and disease New research on epigenetic modifiers in cardiac development Comprehensive coverage of stem cells and prospects for cardiac regeneration Up-to-date research on transcriptional and proteomic circuits in cardiac disease Full-color, detailed illustrations

✏Book Title : Endocardial Cell Plasticity in Cardiac Development Diseases and Regeneration
✏Author :
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1051332815
✏Available Language : English, Spanish, And French

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✏Endocardial Cell Plasticity in Cardiac Development Diseases and Regeneration Book Summary : Abstract : Endocardial cells are specialized endothelial cells that form the innermost layer of the heart wall. By virtue of genetic lineage–tracing technology, many of the unexpected roles of endocardium during murine heart development, diseases, and regeneration have been identified recently. In addition to heart valves developed from the well-known endothelial to mesenchymal transition, recent fate-mapping studies using mouse models reveal that multiple cardiac cell lineages are also originated from the endocardium. This review focuses on a variety of different cell types that are recently reported to be endocardium derived during murine heart development, diseases, and regeneration. These multiple cell fates underpin the unprecedented roles of endocardial progenitors in function, pathological progression, and regeneration of the heart. Because emerging studies suggest that developmental mechanisms can be redeployed and recapitulated in promoting heart disease development and also cardiac repair and regeneration, understanding the mechanistic regulation of endocardial plasticity and modulation of their cell fate conversion may uncover new therapeutic potential in facilitating heart regeneration.

✏Book Title : Cardiac Regeneration using Stem Cells
✏Author : Keiichi Fukuda
✏Publisher : CRC Press
✏Release Date : 2013-04-10
✏Pages : 342
✏ISBN : 9781466578401
✏Available Language : English, Spanish, And French

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✏Cardiac Regeneration using Stem Cells Book Summary : To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.

✏Book Title : Heart Development
✏Author :
✏Publisher : Academic Press
✏Release Date : 2012-05-10
✏Pages : 408
✏ISBN : 9780123877901
✏Available Language : English, Spanish, And French

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✏Heart Development Book Summary : The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research

✏Book Title : Biomaterials for Cardiac Regeneration
✏Author : Erik J. Suuronen
✏Publisher : Springer
✏Release Date : 2014-11-12
✏Pages : 323
✏ISBN : 9783319109725
✏Available Language : English, Spanish, And French

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✏Biomaterials for Cardiac Regeneration Book Summary : This book offers readers a comprehensive biomaterials-based approach to achieving clinically successful, functionally integrated vasculogenesis and myogenesis in the heart. Coverage is multidisciplinary, including the role of extracellular matrices in cardiac development, whole-heart tissue engineering, imaging the mechanisms and effects of biomaterial-based cardiac regeneration, and autologous bioengineered heart valves. Bringing current knowledge together into a single volume, this book provides a compendium to students and new researchers in the field and constitutes a platform to allow for future developments and collaborative approaches in biomaterials-based regenerative medicine, even beyond cardiac applications.

✏Book Title : M ller Glia and Notch Signaling in Zebrafish Retinal Development and Regeneration
✏Author : Rebecca L. Bernardos
✏Publisher :
✏Release Date : 2006
✏Pages :
✏ISBN : UOM:39015069227851
✏Available Language : English, Spanish, And French

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✏M ller Glia and Notch Signaling in Zebrafish Retinal Development and Regeneration Book Summary :

✏Book Title : The ESC Textbook of Cardiovascular Development
✏Author : José M. Pérez-Pomares
✏Publisher : Oxford University Press
✏Release Date : 2018-07-12
✏Pages : 384
✏ISBN : 9780191074516
✏Available Language : English, Spanish, And French

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✏The ESC Textbook of Cardiovascular Development Book Summary : This highly illustrated textbook has been prepared by the Working Group on Development, Anatomy and Pathology of the European Society of Cardiology (ESC). The ESC Textbook of Cardiovascular Development is the authority on cardiovascular development from a perspective of both basic scientists and clinicians. The embryonic origin of congenital heart diseases and their pathology has been analysed in depth. Modern concepts pivotal to the understanding of cardiovascular morphogenesis, including those still subject to controversy, have been highlighted and the content covers the ESC Core Curriculum. The textbook will appeal to researchers and clinicians from a wide spectrum of disciplines including molecular and developmental biologists working on mechanisms of heart development in a range of model organisms as well as pathologists, morphologists, geneticists, and cardiologists.

✏Book Title : Stem Cells and Myocardial Regeneration
✏Author : Marc S. Penn
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-11-06
✏Pages : 400
✏ISBN : 9781597452724
✏Available Language : English, Spanish, And French

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✏Stem Cells and Myocardial Regeneration Book Summary : Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF). Not that long ago we believed we were born with a set number of cardiac myocytes and that once damaged there was no hope to replace them. The interest in the field stems from the magnitude of cardiovascular disease in the world. Our ability to treat and help patients survive acute myocardial infarction (MI) has resulted in a near epidemic of CHF. There are more than 5 million Americans who currently carry the diagnosis of CHF. With more than 1 million MIs a year in the United States, there are approx 500,000 new cases of CHF diagnosed each year. The goal of Stem Cells and Myocardial Regeneration is to present, in a coherent manner, the current state of knowledge of stem cell-based therapies for cardiac dysfunction, including current findings in both the laboratory and the clinic trials. The first section of this Stem Cells and Myocardial Regeneration focuses on the magnitude of the problem and the successes and failures of what we consider optimal medical therapy. It is on this background that stem cell-based therapy needs to build.

✏Book Title : Cardiac Growth and Regeneration
✏Author : William C. Claycomb
✏Publisher :
✏Release Date : 1995
✏Pages : 525
✏ISBN : UVA:X002594909
✏Available Language : English, Spanish, And French

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✏Cardiac Growth and Regeneration Book Summary : Mammalian cardiac muscle, unlike that in amphibians, reptiles and the mammalian atrium, cannot regenerate after injury, and the mechanism for the irreversible blockage of mitosis in these monocytes during early development is still not understood. This book attempts to study the mechanisms that control the cardiac muscle cell cycle so that treatments to initiate repair of the myocardium can be designed. An ideal model would allow study of cardiac muscle cells in the intact heart in the biochemical state they were in during foetal growth, when they were actively dividing. This volume gathers the most current information dealing with the regenerative potential of cardiac muscle in the vertebrate heart.

✏Book Title : Cardiac Development
✏Author : Margaret L. Kirby
✏Publisher : Oxford University Press
✏Release Date : 2007-03-22
✏Pages : 288
✏ISBN : 019972086X
✏Available Language : English, Spanish, And French

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✏Cardiac Development Book Summary : This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.

✏Book Title : Cardiac Muscle
✏Author : E.D. Canale
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 320
✏ISBN : 9783642501159
✏Available Language : English, Spanish, And French

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✏Cardiac Muscle Book Summary : In the ever-expanding field of heart research the needs of established re searchers, students and general readers can vary considerably, making it difficult therefore to cater for all types of audience within a single volume. The aim of this book has been to provide a comprehensive and up-to-date review of the structure of the heart, including its cell biology. The ultrastructure of the working myocardium and all portions of the conduction system, together with their development, is covered in detail. Also included are chapters on the morphometry of cardiac muscle, the innervation of the heart, cardiac hyper trophy and regeneration, and the development of the coronary circulation. A detailed review of cardiac muscle in cell culture is also provided. It is to be hoped that readers, whatever their background, will find the information contained herein useful for their needs. This work was supported by a grant from the National Heart Foundation of Australia. The authors wish to gratefully acknowledge the following people for their invaluable assistance in preparation of the manuscript: Professor Yasuo Uehara, D'r. Takashi· Fujiwara, Dr. Peter Baluk, Dr. Seiji Matsuda and Bill Kaegi for providing unpublished micrographs; Fabian Bowers, Patricia Murphy and Janet Bennett for typing; and Lucy Popadynec, Nella Puglisi, Maggie Mackie, Mary Delafield and Liana Butera for assistance with references and figure preparation. THE AUTHORS Contents A. General Introduction 1 Morphology of Cardiac Muscle 8 B.

✏Book Title : The Cardiac Lymphatic System
✏Author : Ganga Karunamuni
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-04-23
✏Pages : 184
✏ISBN : 9781461467748
✏Available Language : English, Spanish, And French

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✏The Cardiac Lymphatic System Book Summary : The heart is invested with a complex, intertwining network of blood and lymphatic vessels which, respectively, provide the cardiac tissue with oxygen and nutrients and eliminate excess fluid from the interstitium. The coronary blood vessels have been the focus of much investigation in the past few decades. On the other hand, the literature regarding the cardiac lymphatic vessels remains sparse, despite their important role in maintaining normal heart function. With this in mind, a better understanding of the cardiac lymphatic network and its ability to regulate fluid homeostasis within the heart could give us insight into developing therapies for the alleviation of several cardiac pathological conditions.

✏Book Title : The Physiology of Fishes Fourth Edition
✏Author : David H. Evans
✏Publisher : CRC Press
✏Release Date : 2013-11-25
✏Pages : 491
✏ISBN : 9781439880319
✏Available Language : English, Spanish, And French

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✏The Physiology of Fishes Fourth Edition Book Summary : Following the success of the bestselling third edition, this newly updated and completely revised fourth edition of The Physiology of Fishes provides comprehensive coverage of the most important aspects of the form and function of fishes. It covers the most recent advances as well as fundamental subjects such as cardiovascular physiology, intestinal transport, and gill ion uptake. Written by an international group of experts, this book contains fresh approaches, with completely new treatment of the original topics and the addition of new chapters: Muscle plasticity Membranes and Metabolism Oxygen Sensing Endocrine Disruption Pain Perception Cardiac Regeneration Neuronal Regeneration Two decades after the publication of the first edition, this book remains the only published single-volume work on fish physiology. Each chapter contains an extensive bibliography, providing readers with the best sources from the primary literature. The fourth edition provides an important reference for aquatic biologists, ichthyologists, fisheries scientists, and comparative physiologists.

✏Book Title : Cellular and Molecular Basis of Regeneration
✏Author : Patrizia Ferretti
✏Publisher : John Wiley & Sons Incorporated
✏Release Date : 1998-05-29
✏Pages : 458
✏ISBN : UOM:39015047075414
✏Available Language : English, Spanish, And French

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✏Cellular and Molecular Basis of Regeneration Book Summary : This extensive overview of the fundamental issues that underlie regeneration discusses selected models from invertebrates to mammals. It examines the issues of regeneration from an evolutionary perspective in order to address the issue of why regenerative ability has decreased through evolution and assesses how far we are from increasing the regenerative potential in mammals.

✏Book Title : Research EU
✏Author :
✏Publisher :
✏Release Date : 2012-06
✏Pages :
✏ISBN : MINN:31951D03404792W
✏Available Language : English, Spanish, And French

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✏Research EU Book Summary :

✏Book Title : Hurst s the Heart 14th Edition Two Volume Set
✏Author : Valentin Fuster
✏Publisher : McGraw Hill Professional
✏Release Date : 2017-03-22
✏Pages :
✏ISBN : 9780071842433
✏Available Language : English, Spanish, And French

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✏Hurst s the Heart 14th Edition Two Volume Set Book Summary : Cardiology’s cornerstone text – thoroughly updated to reflect the latest clinical perspectives and cutting-edge topics Hailed for its authority, currency, and ability to translate the latest technical and clinical advances into clinical application, Hurst’s The Heart is the field’s landmark text and cardiology’s longest continuously published reference text. A previous edition of this trusted classic was described by Doody’s as “an outstanding choice for those who strive for a firm foundation in cardiovascular medicine, as well as an up-to-date and user-friendly source that addresses every discipline in the field.” Readers will find succinct, visually appealing summaries of all the major new trials, and guidelines, along with tips for optimizing outcomes and health quality. The Fourteenth Edition has been completely updated to reflect the latest technical, therapeutic, and clinical advances, while still maintaining a strong focus on patient care. Other enhancements include the addition of textual features such as Practice Points, Common Clinical Questions, and an increased number of the acclaimed Hurst’s diagrams. • NEW TO THIS EDITION: Section on Metabolic Disorders and Cardiovascular Disease, Cigarette Smoking and Cardiovascular Disease • Enhanced by more than 1,500 full-color illustrations and more than 500 tables • Brand new chapters include: Arrythmogenic Cardiomyopathy, Ischemic Mitral Regurgitation, Degenerative Mitral Valve Disease, Left Ventricular Noncompaction, Evaluation and Management of Acute Heart Failure, Carotid Artery Stenting, Race, Ethnicity, and Cardiovascular disease • The only comprehensive cardiology reference to publish every 2.5 years to allow for reporting of the latest trials and guidelines

✏Book Title : Growth and Hyperplasia of Cardiac Muscle Cells
✏Author : P. P. Rumyantsev
✏Publisher : Taylor & Francis
✏Release Date : 1991
✏Pages : 376
✏ISBN : 3718649586
✏Available Language : English, Spanish, And French

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✏Growth and Hyperplasia of Cardiac Muscle Cells Book Summary : Proliferative activity of cardiomyocytes and polyploidization of their nuclei during myocardial hypertrophy of non-primates -- On the possibility of an increase in the number of cardiomyocytes during ventricular hypertrophy -- Chapter 6 Unusual Proliferative Behaviour of Adult Mammalian Atrial Cardiomyocytes -- Hyperplasia of rat atrial cardiomyocytes mediated by experimental left venticular infarction -- DNA synthesis and mitotic activity of atrial myocytes during myocardial hypertrophy -- Changes in the ultrastructure of myocytes of the rat left atrium after experim ental left ventricular infarction -- Chapter 7 On the Possibility of Reactivation of Proliferative Processes in Cardiomyocytes of the Conducting System -- Chapter 8 A Paradoxical Capacity of Working Myocytes of the Overloaded Heart of Man and Primates for Polyploidization -- DNA content in the nuclei of cardiomyocytes during cardiac hyperfunction and hypertrophy -- The question of hyperplasia of human cardiomyocytes during cardiac hypertrophy -- Signs of hyperplasia of perinecrotic cardiomyocytes -- Tumors of the myocardium -- Chapter 9 Attempts to Stimulate Myocardial Regeneration -- Part III Modulation of Processes of Cardiomyocyte Differentiation and Proliferation in Vitro and in Tissue Transplants -- Chapter 10 Modulations of Differentiation in Tissue Explants of the M yocardium In Vitro -- Chapter 11 Processes of Cardiomyocyte Proliferation and Differentiation in Cell Culture -- Chapter 12 Regenerative Morphogenesis During Auto- and Heterotranspiantation of Myocardial Tissue Grafts -- Conclusion -- References -- Subject Index

✏Book Title : Mechanical Circulatory Support A Companion to Braunwald s Heart Disease Ebook
✏Author : Robert L. Kormos
✏Publisher : Elsevier Health Sciences
✏Release Date : 2011-08-30
✏Pages : 384
✏ISBN : 9781455727001
✏Available Language : English, Spanish, And French

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✏Mechanical Circulatory Support A Companion to Braunwald s Heart Disease Ebook Book Summary : Mechanical Circulatory Support, by Drs. Robert L. Kormos and Leslie W. Miller, provides the clinically relevant information you need to effectively use this therapy to treat and manage end-stage cardiovascular disease. In this Companion to Braunwald’s Heart Disease, the world’s most prominent experts in mechanical circulatory support (MCS) cover basic science, device construction, clinical applications, socioeconomic implications, future directions, and more. Stay on top of hot topics - including innovative devices like continuous flow pumps, next-generation centrifugal pumps, and total artificial hearts; MCS for pediatric and congenital heart disease; cellular, molecular, genomic, and functional changes that occur in the failing heart in response to MCS; and Interagency Registry of Mechanically Assisted Circulatory Support (INTERMACS) as a tool to track and advance clinical practice. Tap into discussions of hot topics in mechanical circulatory support (MCS), including current types of devices and clinical settings for MCS; MCS for pediatric and congenital heart disease; myocardial recovery, regenerative therapy, bleeding and thrombosis with MCS; cellular, molecular, genomic, and functional changes that occur in the failing heart in response to MCS; and Interagency Registry of Mechanically Assisted Circulatory Support (INTERMACS) as a tool to track and advance clinical practice. Get a complete picture of the role of mechanical circulatory support in treatment through coverage of device construction, clinical applications, socioeconomic implications, and future directions. Master the pathophysiology and rationale of treatment with discussions of basic science in addition to clinically-relevant information and current clinical practice guidelines. Apply the expertise of the world’s most prominent leaders in mechanical circulatory support.

✏Book Title : Valvular Heart Disease A Companion to Braunwald s Heart Disease E Book
✏Author : Catherine M. Otto
✏Publisher : Elsevier Health Sciences
✏Release Date : 2009-09-18
✏Pages : 468
✏ISBN : 9781437721478
✏Available Language : English, Spanish, And French

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✏Valvular Heart Disease A Companion to Braunwald s Heart Disease E Book Book Summary : Valvular Heart Disease is now an even better source for all your questions on dysfunctions or abnormalities of the heart’s four valves. In the third edition, Catherine Otto is joined by Robert Bonow and a team of expert contributors to bring you the latest developments in imaging and treatment. The full-color images and illustrations reflect the cutting-edge imaging and diagnostic modalities—Doppler echo and MR—that are so important for diagnosing aortic valve defects. Superb diagrams, an increased focus on imaging and case-based presentation, and new chapters—on Cardiac MR and CT imaging for valvular heart disease; Genetic, molecular and cellular mechanisms of valvular disease; Bicuspid aortic valve disease; and Ischemic mitral regurgitation—further enhance this valuable reference. Presents comprehensive coverage of valvular heart disease to provide you with a complete reference and one-stop shop for this specialty in cardiac medicine. Provides complete guidance on how and why to surgically treat valve patients for a reliable manual on managing difficult cases. Features chapters on pediatric and pregnant patients so you know what considerations to take into account when treating these special populations. Introduces Robert Bonow as an editor, who joins Catherine Otto and the team of expert authors to provide you with guidance from leaders in the field. Features new chapters—Genetic, molecular and cellular mechanisms of valvular disease; Bicuspid aortic valve disease; and Ischemic mitral regurgitation—for the latest in cutting-edge research and clinical data. Reflects the latest in imaging modalities in the new section on cardiac MR and CT imaging for valvular heart disease to provide you with a full understand of the tools for the most accurate diagnosis. Presents detailed illustrations and images in full color to better showcase valve anatomy and dysfunction, as well as important techniques and surgical procedures. Includes a summary of the new ACC/AHA valvular heart disease guidelines in each chapter to keep you up to date on the latest best practices throughout the field.

✏Book Title : Introduction to Translational Cardiovascular Research
✏Author : Dennis V. Cokkinos
✏Publisher : Springer
✏Release Date : 2014-11-06
✏Pages : 610
✏ISBN : 9783319087986
✏Available Language : English, Spanish, And French

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✏Introduction to Translational Cardiovascular Research Book Summary : The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and the hypothalamic-pituitary-adrenal axis, while covering genetic polymorphisms both generally and specifically as regards the vascular endothelium and the use of microRNAs. As such, this book will be relevant to young physicians, nurses and other scientists engaged in the clinical cardiovascular field who want to added research-oriented dimension to their efforts towards better understanding and practicing of medicine. It also aims to attract young basic researchers who want to develop a better comprehension of the organism as a whole, man or animal, that they are investigating.

✏Book Title : Cardiac Regeneration and Repair
✏Author : Ren-Ke Li
✏Publisher : Elsevier
✏Release Date : 2014-02-17
✏Pages : 486
✏ISBN : 9780857096715
✏Available Language : English, Spanish, And French

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✏Cardiac Regeneration and Repair Book Summary : Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure. Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels. Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. Surveys the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Focuses on tissue engineering for cardiac repair including clinical considerations for cardiac tissue engineering Explores vascular remodeling, highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels

✏Book Title : Regeneration
✏Author : William Anderson
✏Publisher :
✏Release Date : 1875
✏Pages : 319
✏ISBN : HARVARD:HWJSQ4
✏Available Language : English, Spanish, And French

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✏Regeneration Book Summary :

✏Book Title : Heart Regeneration
✏Author : Felix B. Engel
✏Publisher : World Scientific
✏Release Date : 2012
✏Pages : 372
✏ISBN : 9789814299800
✏Available Language : English, Spanish, And French

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✏Heart Regeneration Book Summary : This title presents the major advances of the last decade in the field of cardiac regeneration.

✏Book Title : Heart Failure
✏Author : José Marín-García
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-06-23
✏Pages : 470
✏ISBN : 9781607611479
✏Available Language : English, Spanish, And French

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✏Heart Failure Book Summary : Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies. Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF. Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. This book thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers. Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.

✏Book Title : Introduction to Embryonic Development
✏Author : Steven B. Oppenheimer
✏Publisher : Allyn & Bacon
✏Release Date : 1984
✏Pages : 482
✏ISBN : UCAL:B4456510
✏Available Language : English, Spanish, And French

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✏Introduction to Embryonic Development Book Summary :

✏Book Title : Stem Cells Regenerative Medicine
✏Author : Krishnarao Appasani
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-11-01
✏Pages : 629
✏ISBN : 1607618605
✏Available Language : English, Spanish, And French

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✏Stem Cells Regenerative Medicine Book Summary : Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.

✏Book Title : Rebuilding the Infarcted Heart
✏Author : Loren J. Field
✏Publisher : CRC Press
✏Release Date : 2007-12-10
✏Pages : 238
✏ISBN : 0203089731
✏Available Language : English, Spanish, And French

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✏Rebuilding the Infarcted Heart Book Summary : Revascularization of the heart is the prime objective following a myocardial infarction as the morbidity inflicted severely impacts the patient's lifestyle and working capabilities. The use of stem cell transplantation is one route that is receiving considerable funding from government and private sources. This book examines the various methods available that will help the patient to recover from the adverse effects of a myocardial infarction. This book takes the reader from bench to bedside, from chalk to dust, and explains in clear detail how the mechanisms of stem cell transplantation work.

✏Book Title : Loss and Restoration of Regenerative Capacity in Tissues and Organs of Animals
✏Author : Lev Vladimirovich Polezhaev
✏Publisher : Harvard University Press
✏Release Date : 1972
✏Pages : 385
✏ISBN : 0674539206
✏Available Language : English, Spanish, And French

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✏Loss and Restoration of Regenerative Capacity in Tissues and Organs of Animals Book Summary : This well-illustrated monograph is the first summary in English of L.V. Polezhaev's important but lesser known work on the regenerative phenomena in mammalian forms, conducted since World War II. During this period Soviet research underwent a pronounced shift in emphasis from basic biological studies based primarily upon amphibians to more practically oriented problems in mammalian systems. Polezhaev's experimentation underwent a corresponding shift, but the focus on restoration of lost regenerative capacity was retained since his earlier work, which is also reviewed here, on limb regeneration in frogs. Following a theoretical discussion, the monograph centers upon the author's most profound innovations: a successful method for producing bone to heal large skull defects, original research on heart regeneration, and trials in the restoration of limb regeneration following X-irradiation.

✏Book Title : Molecular Mechanisms of Adult Stem Cell Aging
✏Author : K.L. Rudolph
✏Publisher : Karger Medical and Scientific Publishers
✏Release Date : 2010-04-22
✏Pages : 116
✏ISBN : 9783805592444
✏Available Language : English, Spanish, And French

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✏Molecular Mechanisms of Adult Stem Cell Aging Book Summary : There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology.

✏Book Title : The Physiology of Bioelectricity in Development Tissue Regeneration and Cancer
✏Author : Christine E. Pullar
✏Publisher : CRC Press
✏Release Date : 2016-04-19
✏Pages : 342
✏ISBN : 1439837244
✏Available Language : English, Spanish, And French

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✏The Physiology of Bioelectricity in Development Tissue Regeneration and Cancer Book Summary : Recent advances in technology have led to the unprecedented accuracy in measurements of endogenous electric fields around sites of tissue disruption. State-of-the-art molecular approaches demonstrate the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. New information indicates that electric fields play a role in initiating and coordinating complex regenerative responses in development and wound repair and that they may also have a part in cancer progression and metastasis. Compiling current research in this rapidly expanding field, Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer highlights relevant, cutting-edge topics poised to drive the next generation of medical breakthroughs. Chapters consider methods for detecting endogenous electric field gradients and studying applied electric fields in the lab. The book addresses bioelectricity’s roles in guiding cell behavior during morphogenesis and orchestrating higher order patterning. It also covers the response of stem cells to applied electric fields, which reveals bioelectricity as an exciting new player in tissue engineering and regenerative medicine. This book provides an in-depth exploration of how electric signals control corneal wound repair and skin re-epithelialization, angiogenesis, and inflammation. It also delves into the bioelectric responses of cells derived from the musculoskeletal system, bioelectrical guidance of neurons, and the beneficial application of voltage gradients to promote regeneration in the spinal cord. It concludes with a discussion of bioelectricity and cancer progression and the potential for novel cancer biomarkers, new methods for early detection, and bioelectricity-based therapies to target both the tumor and metastatic cancer cells. This multidisciplinary compilation will benefit biologists, biochemists, biomedical scientists, engineers, dermatologists, and clinicians, or anyone else interested in development, regeneration, cancer, and tissue engineering. It can also serve as an ideal textbook for students in biology, medicine, medical physiology, biophysics, and biomedical engineering.