Heart Development and Regeneration

• Author : Nadia Rosenthal,Richard P. Harvey
• Publisher : Academic Press
• Release : 28 May 2010

The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution

• Author : Felix B. Engel
• Publisher : Unknown
• Release : 03 July 2022

• Author : Benoit G. Bruneau
• Publisher : Academic Press
• Release : 03 July 2022

The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research

• Author : Erik J. Suuronen,Marc Ruel
• Publisher : Springer
• Release : 12 November 2014

This book offers readers a comprehensive biomaterials-based approach to achieving clinically successful, functionally integrated vasculogenesis and myogenesis in the heart. Coverage is multidisciplinary, including the role of extracellular matrices in cardiac development, whole-heart tissue engineering, imaging the mechanisms and effects of biomaterial-based cardiac regeneration, and autologous bioengineered heart valves. Bringing current knowledge together into a single volume, this book provides a compendium to students and new researchers in the field and constitutes a platform to allow for future developments and

• Author : Wenjie Yao
• Publisher : Unknown
• Release : 03 July 2022

• Author : Anonim
• Publisher : Academic Press
• Release : 10 May 2012

The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research

• Author : Michael Andrew Flinn
• Publisher : Unknown
• Release : 03 July 2022

• Author : Keiichi Fukuda,Shinsuke Yuasa
• Publisher : CRC Press
• Release : 10 April 2013

To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with

• Author : Ngoc Nguyen
• Publisher : Unknown
• Release : 03 July 2022

There are tremendous health and financial burdens attributed to cardiovascular disease. The most common type, known as ischemic heart disease, is due to plaque buildup within the coronary arteries that supply the myocardium with oxygen and nutrients. Reduction or blockage of blood flow can lead to irreversible loss of cardiomyocytes, the main building blocks of the heart, with estimates placing that loss to upward of a billion cells. Despite medical therapy, the majority of patients eventually progress to heart failure,

• Author : Işil Tekeli
• Publisher : Unknown
• Release : 03 July 2022

Zebrafish heart regeneration remains one of the most interesting phenomena of the 21st century. Considering the extremely high rate of deaths due to cardiovascular diseases in the developed countries, 1 out of every 3 people, understanding natural cardiac regeneration would address a worldwide challenge. Even though many aspects of zebrafish heart regeneration have been elucidated, there are still many open questions to be answered. Among these, the work presented here focuses on understanding cell migration mechanisms of cardiomyocytes and epicardial cells during

• Author : Vahid Serpooshan,Sean M. Wu
• Publisher : Springer
• Release : 29 June 2019

This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins

• Author : Anonim
• Publisher : Unknown
• Release : 03 July 2022

• Author : Anonim
• Publisher : Unknown
• Release : 03 July 2022

Zebrafish (Danio rerio) are an established vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryo-larvae exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibit severe heart malformation. Thus, we sought to determine if epicardium development was affected by TCDD exposure. TCDD exposure prevents development of the epicardial progenitors (proepicardium; PE) and subsequent formation of the epicardium. Exposure to TCDD later in development, after the epicardium has formed, does not

• Author : Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi
• Publisher : Springer
• Release : 24 June 2016

This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide

• Author : José M. Pérez-Pomares,Robert Kelly
• Publisher : Oxford University Press
• Release : 12 July 2018

This highly illustrated textbook has been prepared by the Working Group on Development, Anatomy and Pathology of the European Society of Cardiology (ESC). The ESC Textbook of Cardiovascular Development is the authority on cardiovascular development from a perspective of both basic scientists and clinicians. The embryonic origin of congenital heart diseases and their pathology has been analysed in depth. Modern concepts pivotal to the understanding of cardiovascular morphogenesis, including those still subject to controversy, have been highlighted and the content