Targeted Therapy in Translational Cancer Research

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  • Author : Apostolia-Maria Tsimberidou
  • Publisher : John Wiley & Sons
  • Pages : 320 pages
  • ISBN : 1118468686
  • Rating : /5 from reviews
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Download or Read online Targeted Therapy in Translational Cancer Research full in PDF, ePub and kindle. this book written by Apostolia-Maria Tsimberidou and published by John Wiley & Sons which was released on 08 October 2015 with total page 320 pages. We cannot guarantee that Targeted Therapy in Translational Cancer Research book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and the roles of cancer stem cells, the microenvironment, angiogenesis, epigenetics, microRNAs, and functional imaging in precision medicine Summarises major advances in therapeutic management of hematologic malignancies and solid tumors using conventional therapy, targeted therapy, immunotherapy, or novel treatment modalities

Targeted Therapy in Translational Cancer Research

Targeted Therapy in Translational Cancer Research
  • Author : Apostolia-Maria Tsimberidou,Razelle Kurzrock,Kenneth C. Anderson
  • Publisher : John Wiley & Sons
  • Release : 08 October 2015
GET THIS BOOK Targeted Therapy in Translational Cancer Research

Targeted Therapy in Translational Cancer Research for the Translational Oncology series provides a comprehensive overview of recent developments in our understanding of tumor biology, elucidates the roles of targets and pathways involved in carcinogenesis, and describes current state-of-the-art anticancer therapy, as well as the most promising areas of translational research and targeted therapy. Introduces cutting-edge ‘bench to bedside and back’ breakthroughs which have transformed the diagnosis, prognosis, and treatment of cancer Covers basic principles of targeted therapy, including immunotherapy and

Hands On Approach for the Conduct of Nonclinical Studies

Hands On Approach for the Conduct of Nonclinical Studies
  • Author : Deven Dandekar,Pallavi B. Limaye
  • Publisher : Academic Press
  • Release : 01 March 2019
GET THIS BOOK Hands On Approach for the Conduct of Nonclinical Studies

Hands-on Approach for the Conduct of Nonclinical Studies: A Manual for Anticipating and Avoiding Potential Problems focuses on practical approaches to real-life challenges faced during nonclinical studies, providing insights into the anticipation of potential problems and solutions to problems which may arise, saving time, money and resources. The book outlines Good Laboratory Practice in detail and includes regulatory guidelines, communication, stakeholder information and case studies. It is essential reading for study directors/technical coordinators, quality assurance personnel, all technical staff

Pharmaceutical Toxicology in Practice

Pharmaceutical Toxicology in Practice
  • Author : Alberto Lodola,Jeanne Stadler
  • Publisher : John Wiley & Sons
  • Release : 31 March 2011
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This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with

Translational Medicine

Translational Medicine
  • Author : Joy A. Cavagnaro,Mary Ellen Cosenza
  • Publisher : CRC Press
  • Release : 26 November 2021
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Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for

Global Approach in Safety Testing

Global Approach in Safety Testing
  • Author : Jan Willem van der Laan,Joseph J DeGeorge
  • Publisher : Springer Science & Business Media
  • Release : 11 February 2013
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This volume will consider one of ICH’s major categories, Safety i.e. topics relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.). Since the start of the ICH process, many guidelines have been written, but even after ICH6 no explanations have been given during a formal Congress about the background of the ICH Guidance documents. Even more important than what has been written, might have been those thoughts of the experts that are not

The Role of the Study Director in Nonclinical Studies

The Role of the Study Director in Nonclinical Studies
  • Author : William J. Brock,Barbara Mounho,Lijie Fu
  • Publisher : John Wiley & Sons
  • Release : 02 May 2014
GET THIS BOOK The Role of the Study Director in Nonclinical Studies

A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives. The book: Provides a complete overview of nonclinical study organization, conduct, and reporting and describes the roles and responsibilities of a Study Director to manage an effective study Covers regulatory and scientific concepts, including international testing and Good Laboratory Practice (GLP), compliance with guidelines, and animal

Handbook of Bioequivalence Testing

Handbook of Bioequivalence Testing
  • Author : Sarfaraz K. Niazi
  • Publisher : CRC Press
  • Release : 29 October 2014
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As the generic pharmaceutical industry continues to grow and thrive, so does the need to conduct adequate, efficient bioequivalence studies. In recent years, there have been significant changes to the statistical models for evaluating bioequivalence. In addition, advances in the analytical technology used to detect drug and metabolite levels have m

Management of Animal Care and Use Programs in Research Education and Testing

Management of Animal Care and Use Programs in Research  Education  and Testing
  • Author : Robert H. Weichbrod,Gail A. (Heidbrink) Thompson,John N. Norton
  • Publisher : CRC Press
  • Release : 07 September 2017
GET THIS BOOK Management of Animal Care and Use Programs in Research Education and Testing

AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all

A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release : 16 November 2012
GET THIS BOOK A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release : 03 November 2016
GET THIS BOOK A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of

Handbook of LC MS Bioanalysis

Handbook of LC MS Bioanalysis
  • Author : Wenkui Li,Jie Zhang,Francis L. S. Tse
  • Publisher : John Wiley & Sons
  • Release : 03 September 2013
GET THIS BOOK Handbook of LC MS Bioanalysis

Consolidates the information LC-MS bioanalytical scientistsneed to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by newapproaches for developing bioanalytical methods, new liquidchromatographic (LC) techniques, and new mass spectrometric (MS)instruments. Moreover, there are a host of guidelines andregulations designed to ensure the quality of bioanalyticalresults. Presenting the best practices, experimental protocols, and thelatest understanding of regulations, this book offers acomprehensive review of LC-MS bioanalysis of small molecules andmacromolecules. It not only addresses the needs

Neuroethics in Practice

Neuroethics in Practice
  • Author : Anjan Chatterjee,Martha J. Farah
  • Publisher : Oxford University Press
  • Release : 17 January 2013
GET THIS BOOK Neuroethics in Practice

This book explores relevant questions within this multi-faceted and rapidly growing field, and will help to define and foster scholarship within the intersection of neuroethics and clinical neuroscience.

Handbook of Research on Automated Feature Engineering and Advanced Applications in Data Science

Handbook of Research on Automated Feature Engineering and Advanced Applications in Data Science
  • Author : Panda, Mrutyunjaya,Misra, Harekrishna
  • Publisher : IGI Global
  • Release : 08 January 2021
GET THIS BOOK Handbook of Research on Automated Feature Engineering and Advanced Applications in Data Science

In today’s digital world, the huge amount of data being generated is unstructured, messy, and chaotic in nature. Dealing with such data, and attempting to unfold the meaningful information, can be a challenging task. Feature engineering is a process to transform such data into a suitable form that better assists with interpretation and visualization. Through this method, the transformed data is more transparent to the machine learning models, which in turn causes better prediction and analysis of results. Data