Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

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  • Author : G V Sherbet
  • Publisher : Elsevier
  • Pages : 368 pages
  • ISBN : 0123878209
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Download or Read online Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy full in PDF, ePub and kindle. this book written by G V Sherbet and published by Elsevier which was released on 12 July 2011 with total page 368 pages. We cannot guarantee that Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes Aids the development of therapeutic treatments for cancer Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research

Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation  Cancer and Cancer Therapy
  • Author : G V Sherbet
  • Publisher : Elsevier
  • Release : 12 July 2011
GET THIS BOOK Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into

Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Growth Factors and Their Receptors in Cell Differentiation  Cancer and Cancer Therapy
  • Author : Gajanan V. Sherbet
  • Publisher : Unknown
  • Release : 28 July 2011
GET THIS BOOK Growth Factors and Their Receptors in Cell Differentiation Cancer and Cancer Therapy

Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into

Growth Factors and their Receptors in Cancer Metastasis

Growth Factors and their Receptors in Cancer Metastasis
  • Author : Wen G. Jiang,K. Matsumoto,T. Nakamura
  • Publisher : Springer Science & Business Media
  • Release : 11 April 2006
GET THIS BOOK Growth Factors and their Receptors in Cancer Metastasis

about the involvement of signaling Transforming growth factor in tumor development and metastasis. plays a central role in the signaling network that controls morphogenesis, 2. THE BASICS OF growth and cell differentiation in SIGNALING multicellular organisms. The different members of this pleiotropic family of 2. 1. receptor signaling growth and differentiation factors seem to The family of growth factors regulate many processes in human disease consists of more than thirty members in and, in particular, tumor development. humans alone (15, 16). They cluster in Our

Therapeutic Strategies in Cancer Biology and Pathology

Therapeutic Strategies in Cancer Biology and Pathology
  • Author : Gajanan V. Sherbet
  • Publisher : Elsevier
  • Release : 26 July 2013
GET THIS BOOK Therapeutic Strategies in Cancer Biology and Pathology

Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and

Molecular Approach to Cancer Management

Molecular Approach to Cancer Management
  • Author : Gajanan V. Sherbet
  • Publisher : Academic Press
  • Release : 15 June 2017
GET THIS BOOK Molecular Approach to Cancer Management

Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation

Genetic Recombination in Cancer

Genetic Recombination in Cancer
  • Author : Gajanan V. Sherbet
  • Publisher : Elsevier
  • Release : 24 July 2003
GET THIS BOOK Genetic Recombination in Cancer

Genetic recombination is a process of combining genes that leads to the generation of cell variants that possess different characteristics. This process is important to the evolution of a species and to embryonic growth and differentiation. However, this process can also lead to the development of abnormal, cancerous cells. This book reviews the role of genetic recombination in the generation of various cancers and how genetic alterations have been or could be employed to elicit clinically useful information. * Provides detailed

The Genetics of Cancer

The Genetics of Cancer
  • Author : Gajanan V. Sherbet,M. S. Lakshmi
  • Publisher : Academic Press
  • Release : 22 June 1997
GET THIS BOOK The Genetics of Cancer

Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields

Insulin Like Growth Factors

Insulin Like Growth Factors
  • Author : Douglas Yee
  • Publisher : IOS Press
  • Release : 05 December 2021
GET THIS BOOK Insulin Like Growth Factors

Over the past five years there has been an explosion of "targeted therapies" for cancer treatment. In most cases, these therapies have been based on pre-clinical data showing that specific molecules play an important role in regulating the malignant phenotype. In breast cancer, there is compelling rationale that such targeted strategies should be successful. Targeting of estrogen receptor ? (ER?) has proven to be a successful way to reduce breast cancer risk, decrease the risk of death and recurrence in an

Blood Cell Biochemistry

Blood Cell Biochemistry
  • Author : Anthony D. Whetton,John Gordon
  • Publisher : Springer
  • Release : 31 August 1996
GET THIS BOOK Blood Cell Biochemistry

Historically, the field of hematopoietic growth factor research began with the work of Carnot and Deflandre-in 1906 they suggested that the rate of erythropoiesis is regulated by a humoral factor found in the blood, namely, erythropoietin. From this comparatively early start, accelerating progress has been made in erythropoietin research, which demon strates the general trends in this field of study. Erythropoietin was purified to homogeneity by 1977 (from enormous quantities of urine from aplastic anemia patients). Subsequently, the gene for erythropoietin has

Fibroblast Growth Factors Biology And Clinical Application Fgf Biology And Therapeutics

Fibroblast Growth Factors  Biology And Clinical Application   Fgf Biology And Therapeutics
  • Author : Simons Michael
  • Publisher : World Scientific
  • Release : 27 December 2016
GET THIS BOOK Fibroblast Growth Factors Biology And Clinical Application Fgf Biology And Therapeutics

The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a

EGFR Signaling Networks in Cancer Therapy

EGFR Signaling Networks in Cancer Therapy
  • Author : John D. Haley,William John Gullick
  • Publisher : Springer Science & Business Media
  • Release : 01 March 2009
GET THIS BOOK EGFR Signaling Networks in Cancer Therapy

The epidermal gro wth factor (EGF ) receptor and its downstream signal transduction networks have been implicated in the ontology and maintenance of tumor tissues, which has motivated the discovery and development of molecularly targeted anti-EGF receptor therapies. Over decades of study, the EGF receptor structure, its ligand binding domains, the physical biochemistry underlying its intrinsic tyrosine kinase catalytic function and the modular interactions with SH2, PTB, and SH3 domain containing signaling adaptor p- teins required for signal transduction, have been

Insulin like Growth Factor Receptor Signalling

Insulin like Growth Factor Receptor Signalling
  • Author : Derek Leroith,Walter Zumkeller,Robert C. Baxter
  • Publisher : Springer Science & Business Media
  • Release : 31 July 2003
GET THIS BOOK Insulin like Growth Factor Receptor Signalling

Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its significance in growth and development, the insulin-like growth factor system also has important roles in a wide variety of pathological states. This has led to interest in the therapeutic potential of insulin-like growth factors and their binding

The Effects of Insulin Like Growth Factors on Human G292 Osteosarcoma Cells

The Effects of Insulin Like Growth Factors on Human G292 Osteosarcoma Cells
  • Author : Thabet AlHousami
  • Publisher : Unknown
  • Release : 05 December 2021
GET THIS BOOK The Effects of Insulin Like Growth Factors on Human G292 Osteosarcoma Cells

Introduction: Osteosarcoma is the most common bone sarcoma in children and adolescents. It is an aggressive primary bone cancer recognized by abnormal cell proliferation and function. The insulin-like growth factor (IGF) system plays an integral role in the growth, differentiation, and developmental processes, and is involved in various physiological and pathological events. The IGF system consists of IGF I and II, their cell surface receptors and insulin-like growth factor binding proteins (IGFBP). IGF-binding proteins (IGFBPs) are important modulators of IGF

Genes Oncogenes and Hormones

Genes  Oncogenes  and Hormones
  • Author : Robert B. Dickson,Marc E. Lippman
  • Publisher : Springer Science & Business Media
  • Release : 31 October 1992
GET THIS BOOK Genes Oncogenes and Hormones

This volume is the third edited by Drs. Dickson and Lippman in the `Advances in Cellular and Molecular Biology of Breast Cancer' series. It continues to explore the scientific thermes begun in the first two volumes: oncogenes and antioncogenes, growth factors, steriods, and stromalepithelial interactions. Rapid and important progress has continued to take place in all of these areas, especially the possibility that the new molecular understanding of regulation of growth, differentiation and metastases will lead to better tumor prognosis

Cytokines

Cytokines
  • Author : C. Bondy,D. LeRoith
  • Publisher : Elsevier
  • Release : 18 April 1997
GET THIS BOOK Cytokines

Progress in molecular technology in recent years has caused an amazing growth of information about intercellular peptide messengers and their receptors. The number of characterized interleukins for example numbered just three six years ago and now there are at least 16. In addition, the number of described neutrophic peptides is around 30 and the number of receptors is ever increasing. Because many of these new peptide ligands and receptors were identified by "reverse genetic" techniques the understanding of their biological roles falls