Gene Therapy for Neurological Disorders and Brain Tumors

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  • Author : E. Antonio Chiocca
  • Publisher : Springer Science & Business Media
  • Pages : 458 pages
  • ISBN : 1592594786
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Gene Therapy for Neurological Disorders and Brain Tumors

Download or Read online Gene Therapy for Neurological Disorders and Brain Tumors full in PDF, ePub and kindle. this book written by E. Antonio Chiocca and published by Springer Science & Business Media which was released on 23 October 1997 with total page 458 pages. We cannot guarantee that Gene Therapy for Neurological Disorders and Brain Tumors book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders.

Gene Therapy for Neurological Disorders and Brain Tumors

Gene Therapy for Neurological Disorders and Brain Tumors
  • Author : E. Antonio Chiocca,Xandra O. Breakefield
  • Publisher : Springer Science & Business Media
  • Release : 23 October 1997
GET THIS BOOK Gene Therapy for Neurological Disorders and Brain Tumors

Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potential strategies against neurologic disorder, and the limitations of today's gene therapy approaches. Also discussed are significant applications of gene therapy to brain tumors, Parkinson's disease, ischemia, and Huntington's chorea. Readers will learn the current delivery

Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders
  • Author : Fredric P. Manfredsson
  • Publisher : Humana Press
  • Release : 23 August 2016
GET THIS BOOK Gene Therapy for Neurological Disorders

This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene

Gene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders
  • Author : Mingjie Li,B. Joy Snider
  • Publisher : Academic Press
  • Release : 25 May 2018
GET THIS BOOK Gene Therapy in Neurological Disorders

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific

Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders
  • Author : Pedro R. Lowenstein,Maria G. Castro
  • Publisher : CRC Press
  • Release : 01 May 2006
GET THIS BOOK Gene Therapy for Neurological Disorders

Coedited by internationally recognized leaders in gene therapy research, this guide supplies the most recent advances, studies, and expert opinion on gene therapy for neurological disorders. Spanning conditions such as Parkinsons's and Alzheimer's disease, multiple sclerosis, brain tumors, stroke, epilepsy, and brain and spinal cord trauma, this reference presents the basic science and applications of recombinant gene products, immune and stem cell-mediated therapeutic strategies, and brain tumor gene therapy.

Protocols for Gene Transfer in Neuroscience

Protocols for Gene Transfer in Neuroscience
  • Author : P. R. Lowenstein,L. W. Enquist
  • Publisher : John Wiley & Sons Incorporated
  • Release : 25 July 1996
GET THIS BOOK Protocols for Gene Transfer in Neuroscience

Protocols for Gene Transfer in Neuroscience Towards Gene Therapy of Neurological Disorders Edited by P. R. Lowenstein University of Manchester, UK and L. W. Enquist Princeton University, USA The brain and the cells that compose it have always presented unique barriers to any kind of outside interventions, including drug delivery, surgical procedures and the genetic manipulation of cells. However, these barriers are now being bypassed by the new technology of gene delivery. Protocols for Gene Transfer in Neuroscience is the

Gene Delivery and Therapy for Neurological Disorders

Gene Delivery and Therapy for Neurological Disorders
  • Author : Xuenong Bo,Joost Verhaagen
  • Publisher : Humana Press
  • Release : 05 October 2016
GET THIS BOOK Gene Delivery and Therapy for Neurological Disorders

This volume aims to explore the latest developments in adeno-associated viral and lentiviral vectors as well as the gene therapy strategies for the most common neurological disorders, followed by chapters that include step-by-step guides to viral vector-based gene delivery in animal models used in the authors’ laboratories. Although safe gene manipulation in neural cells can be achieved, it may still be years away from efficacious gene-based treatment of neurological disorders such as Parkinson's and Alzheimer’s diseases due to the

Pediatric Neurology Part III

Pediatric Neurology Part III
  • Author : Patrick Aubourg
  • Publisher : Elsevier Inc. Chapters
  • Release : 24 April 2013
GET THIS BOOK Pediatric Neurology Part III

Though heavily hyped in the early 1990s as the answer to many genetic diseases, gene therapy has largely failed to live up to its promises up to now. The scientific challenges of conveying replacement genes into the brain have prevented it from having an impact on more than a handful of conditions. In addition, gene therapy has been beset by safety problems. During the last 5 years, new vectors and techniques have started to resolve not only safety issues that once

Gene Therapy of the Central Nervous System From Bench to Bedside

Gene Therapy of the Central Nervous System  From Bench to Bedside
  • Author : Michael G. Kaplitt,Matthew During
  • Publisher : Gulf Professional Publishing
  • Release : 26 October 2021
GET THIS BOOK Gene Therapy of the Central Nervous System From Bench to Bedside

Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two

Proceedings of 6th International Conference and Exhibition on Cell and Gene Therapy 2018

Proceedings of 6th International Conference and Exhibition on Cell and Gene Therapy 2018
  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release : 26 October 2021
GET THIS BOOK Proceedings of 6th International Conference and Exhibition on Cell and Gene Therapy 2018

Mar 27-28, 2017 Madrid, Spain Key Topics : Cell Therapy, Cellular Therapy Technologies, Cell Therapy of Cardiovascular Disorders, Cell Therapy for Cancer, Cell Culture & Bioprocessing:, Cell Science & Stem Cell Research:, Cell Line Development, Tissue Science & Regenerative Medicine, Gene Therapy, Viral gene therapy, Diabetis Gene Therapy, Vectors for Gene Therapy, Molecular Epigenetics, Genetics & Genomic Medicine, Gene Therapy Commercialization, Clinical trials in cell and gene therapy, Gene Therapy for rare & Common Diseases, Gene Editing Technology, Cell Therapy for Neurological Disorders, Ethical Issues in Cell &

Textbook of Neurogenetics

Textbook of Neurogenetics
  • Author : Adriano Jiménez Escrig
  • Publisher : Unknown
  • Release : 01 September 2007
GET THIS BOOK Textbook of Neurogenetics

This text constitutes a comprehensive sinopsis of our current knowledge of thegenetics on neurological diseases. The book presents the wiews from various disciplines who share a common interest on Neurogenetics. The first sever chapters review basic genetics, from historical aspectcs to molecular genetic tools, the internet resources, and the statistics and software used in research and clinical ground. The remaining fourteen chapters provide valuable information on causes, clinical aspects, genetic diagnosis, treatment strategies and management of the main hereditary neurological

Viral Vectors for Treating Diseases of the Nervous System

Viral Vectors for Treating Diseases of the Nervous System
  • Author : David S. Latchman
  • Publisher : Gulf Professional Publishing
  • Release : 05 September 2003
GET THIS BOOK Viral Vectors for Treating Diseases of the Nervous System

Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. Viral Vectors for Treating Disease of the Nervous System describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system.

Anti Apoptotic Activity of the Herpes Simplex Virus Type 2 Gene ICP10 PK

Anti Apoptotic Activity of the Herpes Simplex Virus Type 2 Gene ICP10 PK
  • Author : Dana Perkins
  • Publisher : Createspace Independent Publishing Platform
  • Release : 30 December 2009
GET THIS BOOK Anti Apoptotic Activity of the Herpes Simplex Virus Type 2 Gene ICP10 PK

PhD Thesis (2002). Apoptosis is an etiologic component of neurodegenerative disorders [e.g. Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS)] and acute brain injury ischemia/hypoxia and trauma). Previous studies have shown that a Herpes Simplex Virus Type 2 (HSV-2) gene, ICP10 PK, activates the Ras/MEK/ERK pathway in non-neuronal cells. Because this pathway was implicated in neuronal cell survival, the present studies tested whether ICP10 PK blocks apoptosis in various experimental paradigms of neuronal apoptosis. The broad anti-apoptotic activity of