Formulation of Monoclonal Antibody Therapies

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  • Author : Amal Ali Elkordy
  • Publisher : Academic Press
  • Pages : 245 pages
  • ISBN : 9780128233658
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Formulation of Monoclonal Antibody Therapies

Download or Read online Formulation of Monoclonal Antibody Therapies full in PDF, ePub and kindle. this book written by Amal Ali Elkordy and published by Academic Press which was released on 15 October 2021 with total page 245 pages. We cannot guarantee that Formulation of Monoclonal Antibody Therapies book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be administered. The industrial point of view and the clinical application of mAbs including in oncology, general medicine, rheumatology, hematology, dermatology, gastrointestinal tract, metabolic diseases and dentistry. Formulation of Monoclonal Antibody Therapies: From Lab to Market is essential reading for researchers in biotechnology and biopharmaceutical fields, academics and pharmaceutical industrial scientists, and university students in pharmaceutical and biopharmaceutical sciences. Covers details of recent advances in using mAbs Examines how to overcome the challenges for formulations of therapeutic mAbs Includes liposomal forms of mAbs

Formulation of Monoclonal Antibody Therapies

Formulation of Monoclonal Antibody Therapies
  • Author : Amal Ali Elkordy
  • Publisher : Academic Press
  • Release : 15 October 2021
GET THIS BOOK Formulation of Monoclonal Antibody Therapies

Formulation of Monoclonal Antibody Therapies: From Lab to Market covers a wide range of topics about therapeutic monoclonal antibodies (mAbs) with a focus on formulation aspects. Therapeutic monoclonal antibodies are used for treatment of chronic diseases. It brings together a comprehensive knowledge in one accessible volume. Starting with foundational information on monoclonal antibodies, the book then discusses the importance of biopharmaceutical products, monoclonal antibodies and biosimilars in treatment of chronic diseases, pharmaceutical aspects of mAbs, and how it can be

Pharmaceutical Formulation Development of Peptides and Proteins Second Edition

Pharmaceutical Formulation Development of Peptides and Proteins  Second Edition
  • Author : Lars Hovgaard,Sven Frokjaer,Marco van de Weert
  • Publisher : CRC Press
  • Release : 14 November 2012
GET THIS BOOK Pharmaceutical Formulation Development of Peptides and Proteins Second Edition

The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therapeutic peptides and proteins, from the production of active compounds via basic pre-formulation and formulation to the registration of the final product. Providing integrated solutions, this book discusses: The synthesis of peptides and the

Monoclonal Antibodies

Monoclonal Antibodies
  • Author : Lei Zheng
  • Publisher : Unknown
  • Release : 18 January 2022
GET THIS BOOK Monoclonal Antibodies

This ebook provides a thorough overview of antibody therapy development, including antibody selection, formulation development, conjugation, dose determination, pharmacokinetics/pharmacodynamic, labelling for imaging, and more. Case studies of approved antibodies are included, along with a look ahead to the future by reviewing treatments in clinical development.

Novel Approaches and Strategies for Biologics Vaccines and Cancer Therapies

Novel Approaches and Strategies for Biologics  Vaccines and Cancer Therapies
  • Author : Manmohan Singh,Maya Salnikova
  • Publisher : Academic Press
  • Release : 30 December 2014
GET THIS BOOK Novel Approaches and Strategies for Biologics Vaccines and Cancer Therapies

Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. Written by leading authors across academia and industry, this book covers important topics such as unique drug delivery devices, non-parenteral delivery trends, novel

Current Trends in Monoclonal Antibody Development and Manufacturing

Current Trends in Monoclonal Antibody Development and Manufacturing
  • Author : Steven J. Shire,Wayne Gombotz,Karoline Bechtold-Peters,James Andya
  • Publisher : Springer Science & Business Media
  • Release : 11 November 2009
GET THIS BOOK Current Trends in Monoclonal Antibody Development and Manufacturing

Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups involved in the development of this important class of molecules, monoclonal antibodies products will become increasingly prevalent over the next decade. Recently the regulatory review of

Targeted Nanopreparations for Cancer Therapy

Targeted Nanopreparations for Cancer Therapy
  • Author : Radhika Narayanaswamy
  • Publisher : Unknown
  • Release : 18 January 2022
GET THIS BOOK Targeted Nanopreparations for Cancer Therapy

"Cancer therapy in the recent years has evolved with the development of novel targeted drug delivery systems. The conventional chemotherapy approach is plagued by side effects and numerous disadvantages such as low bioavailability, poor solubility of drugs, toxicity, non-specific drug action and so forth. With the main goal of producing a drug delivery vehicle that is optimally designed to address the many limitations associated with the conventional chemotherapy, the work has been designed as follows: Different lipid-based targeted formulations were

High Throughput Formulation Development of Biopharmaceuticals

High Throughput Formulation Development of Biopharmaceuticals
  • Author : Vladimir I. Razinkov,Gerd Kleemann
  • Publisher : Woodhead Publishing
  • Release : 29 September 2016
GET THIS BOOK High Throughput Formulation Development of Biopharmaceuticals

High Throughput Formulation Development of Biopharmaceuticals: Practical Guide to Methods and Applications provides the latest developments and information on the science of stable and safe drug product formulations, presenting a comprehensive review and detailed description of modern methodologies in the field of formulation development, a process starting with candidate and pre-formulation screening in its early development phase and then progressing to the refinement of robust formulations during commercialization in the later phases of development. The title covers topics such as

Protein Therapeutics 2 Volume Set

Protein Therapeutics  2 Volume Set
  • Author : Tristan Vaughan,Jane Osbourn,Bahija Jallal,Raimund Mannhold,Gerd Folkers,Helmut Buschmann
  • Publisher : John Wiley & Sons
  • Release : 04 December 2017
GET THIS BOOK Protein Therapeutics 2 Volume Set

In this practice-oriented handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and other professionals working in drug development. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes

Therapeutic Monoclonal Antibodies

Therapeutic Monoclonal Antibodies
  • Author : Zhiqiang An
  • Publisher : John Wiley & Sons
  • Release : 20 September 2011
GET THIS BOOK Therapeutic Monoclonal Antibodies

70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. First book to address the discovery and development of antibody therapeutics in their entirety. Most chapters contain experimental data to illustrate the principles described in them. Authors provide detailed methodologies that readers can take away with them and use in their own laboratories.

Ultrafiltration of Highly Concentrated Monoclonal Antibody Solutions

Ultrafiltration of Highly Concentrated Monoclonal Antibody Solutions
  • Author : Elaheh Binabaji
  • Publisher : Unknown
  • Release : 18 January 2022
GET THIS BOOK Ultrafiltration of Highly Concentrated Monoclonal Antibody Solutions

Monoclonal antibodies are currently the fastest growing segment of the pharmaceutical industry; these products are used in the treatment of a wide range of diseases including cancers and allergies. Antibody products are administered at high doses since the volume that can be delivered by injection is limited. Although ultrafiltration systems are used for final formulation of essentially all high value recombinant products, it is often challenging if not impossible to achieve the very high final formulation concentrations required for monoclonal

Development of Biopharmaceutical Drug Device Products

Development of Biopharmaceutical Drug Device Products
  • Author : Feroz Jameel,John W. Skoug,Robert R. Nesbitt
  • Publisher : Springer Nature
  • Release : 13 March 2020
GET THIS BOOK Development of Biopharmaceutical Drug Device Products

The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions. Regulatory agencies have raised the bar for the development and manufacture of antibody-based products, expecting to see the use of Quality by Design (QbD) elements demonstrating an in-depth understanding of product and

Development of Antibody Based Therapeutics

Development of Antibody Based Therapeutics
  • Author : Mohammad A. Tabrizi,Gadi G. Bornstein,Scott L. Klakamp
  • Publisher : Springer Science & Business Media
  • Release : 24 April 2012
GET THIS BOOK Development of Antibody Based Therapeutics

Translational strategies for development of antibody-based therapeutics should allow understanding of the relationship between the ‘unit dose’ and ‘unit effect’ with respect to both beneficial and deleterious effects from early stages of development. The flow of information from later to earlier stages of development should provide opportunities to facilitate selection of more effective novel and next-generation drug candidates. Selection and evaluation of relevant biomarkers in early preclinical development in "relevant" animal models should allow for identifying potential risks to humans

Biophysics for Therapeutic Protein Development

Biophysics for Therapeutic Protein Development
  • Author : Linda O. Narhi
  • Publisher : Springer Science & Business Media
  • Release : 26 February 2013
GET THIS BOOK Biophysics for Therapeutic Protein Development

This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where

Formulation and Device Lifecycle Management of Biotherapeutics

Formulation and Device Lifecycle Management of Biotherapeutics
  • Author : Beate Bittner,Johannes Schmidt
  • Publisher : Academic Press
  • Release : 17 January 2022
GET THIS BOOK Formulation and Device Lifecycle Management of Biotherapeutics

Today, the pressure on healthcare costs and resources is increasing, and especially for biopharmaceuticals that require parenteral administration, the inherent complex and invasive dosing procedure adds to the demand for efficient medical management. In light of the COVID-19 pandemic the value of drug delivery technologies in enabling a flexible care setting is broadly recognized. In such a setting, patients and their caregivers can choose the place of drug administration based on individual preferences and capabilities. This includes not only dosing

Stability and Characterization of Protein and Peptide Drugs

Stability and Characterization of Protein and Peptide Drugs
  • Author : Rodney Pearlman,Y. John Wang
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOK Stability and Characterization of Protein and Peptide Drugs

This is the first volume to make available specific case histories of therapeutic proteins and peptides that have been marketed or are currently under clinical testing. The editors have selected a wide range of molecules derived from monoclonal antibodies, recombinant DNA, and natural and chemical sources to provide formulation scientists with practical examples of the deveopment of pharmaceutical products.