Eukaryotic Transcription Factors

Eukaryotic Transcription Factors Book PDF
✏Book Title : Eukaryotic Transcription Factors
✏Author : David Latchman
✏Publisher : Academic Press
✏Release Date : 2010-07-28
✏Pages : 488
✏ISBN : 0080561039
✏Available Language : English, Spanish, And French

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✏Eukaryotic Transcription Factors Book Summary : Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Potential of transcription factors as therapeutic targets in human disease Importance of histone modifications Use of genome-based sequence analysis and high-throughput methods Applications of the chromatin immunoprecipitation (ChIP) assay Transcriptional elongation Regulation by post-translational modifications Regulatory networks and bioinformatics

📒Eukaryotic Transcription Factors ✍ David S. Latchman

Eukaryotic Transcription Factors Book PDF
✏Book Title : Eukaryotic Transcription Factors
✏Author : David S. Latchman
✏Publisher : Academic Press
✏Release Date : 2003-11-21
✏Pages : 384
✏ISBN : 9780080531267
✏Available Language : English, Spanish, And French

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✏Eukaryotic Transcription Factors Book Summary : Now in two-colour throughout, the fourth edition of Eukaryotic Transcription Factors has been completely rewritten and restructured to take into account the tremendous advances in our understanding of transcription factors and the mechanisms by which they act. Considerable emphasis has been given to the interaction between transcription factors and chromatin structure. Also included is an entirely new section on the mediator complex and expansion of the space devoted to co-activators and co-repressors. This book is essential reading for all those who wish to understand the impact of molecular biology on medicine, whatever their speciality. * Major families of eukaryotic transcription factors described * Mechanisms of gene activation and repression analysed * Structure-function relationships indicated * Interaction between transcription factors and chromatin structure described * Roles in inducible and cell type-specific gene expression * Roles in development, differentiation and human diseases including cancer * Methods of study in vitro and in vivo

A Handbook Of Transcription Factors Book PDF
✏Book Title : A Handbook of Transcription Factors
✏Author : Timothy R. Hughes
✏Publisher : Springer Science & Business Media
✏Release Date : 2011-05-10
✏Pages : 306
✏ISBN : 904819069X
✏Available Language : English, Spanish, And French

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✏A Handbook of Transcription Factors Book Summary : Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Structure Function Analysis Of The Eukaryotic Transcription Factor Spt5 Book PDF
✏Book Title : Structure function Analysis of the Eukaryotic Transcription Factor SPT5
✏Author : Christine Emigh-Hutton
✏Publisher :
✏Release Date : 2006
✏Pages : 88
✏ISBN : UCAL:X73974
✏Available Language : English, Spanish, And French

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✏Structure function Analysis of the Eukaryotic Transcription Factor SPT5 Book Summary :

Transcriptional Regulation In Eukaryotes Book PDF
✏Book Title : Transcriptional Regulation in Eukaryotes
✏Author : Michael Carey
✏Publisher : CSHL Press
✏Release Date : 2000
✏Pages : 640
✏ISBN : 0879696354
✏Available Language : English, Spanish, And French

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✏Transcriptional Regulation in Eukaryotes Book Summary : In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.

Proteins In Eukaryotic Transcription Book PDF
✏Book Title : Proteins in Eukaryotic Transcription
✏Author :
✏Publisher : Elsevier
✏Release Date : 2004-03-19
✏Pages : 280
✏ISBN : 0080522416
✏Available Language : English, Spanish, And French

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✏Proteins in Eukaryotic Transcription Book Summary : Protein Transcription is a key element of cellular and organ regulation. Proteins in Eukaryotic Transcription covers structure and function of all major elements associated with transcription. Mechanism of RNA polymerase I Transcription Structure and function of RNA Polymerase II Structure and function of the TFIID complex Functional properties of Chromatin Remodeling Enzymes Posttranslational modification

Interactions Of A Eukaryotic Rna Polymerase Iii Transcription Factor With Promoters Book PDF
✏Book Title : Interactions of a Eukaryotic RNA Polymerase III Transcription Factor with Promoters
✏Author : David James Stillman
✏Publisher :
✏Release Date : 1984
✏Pages : 462
✏ISBN : UCSD:31822003778610
✏Available Language : English, Spanish, And French

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✏Interactions of a Eukaryotic RNA Polymerase III Transcription Factor with Promoters Book Summary :

📒Mechanisms Of Transcription ✍ Bruce Stillman

Mechanisms Of Transcription Book PDF
✏Book Title : Mechanisms of Transcription
✏Author : Bruce Stillman
✏Publisher : CSHL Press
✏Release Date : 1998
✏Pages : 679
✏ISBN : 0879695501
✏Available Language : English, Spanish, And French

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✏Mechanisms of Transcription Book Summary : Complex macromolecular machinery is responsible for gene-specific and cell-type selective patterns of gene expression. How it works is being revealed by increasingly sophisticated molecular dissection of prokaryotic and eukaryotic cells. This volume reviews the results and conclusions of recent studies in gene transcription. It covers events ranging from activation, through promoter recognition, repression, chromosome structure, chromatin remodelling, initiation and elongation, and the regulation of stopping and starting.

Plant Promoters And Transcription Factors Book PDF
✏Book Title : Plant Promoters and Transcription Factors
✏Author : Lutz Nover
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-06-29
✏Pages : 275
✏ISBN : 9783540480372
✏Available Language : English, Spanish, And French

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✏Plant Promoters and Transcription Factors Book Summary : The control of plant gene expression at the transcriptional level is the main subject of this volume. Genetics, molecular biology and gene technology have dramatically improved our knowledge of this event. The functional analysis of promoters and transcription factors provides more and more insights into the molecular anatomy of initiation complexes assembled from RNA polymerase and the multiplicity of helper and control proteins. Formation of specific DNA-protein complexes - activating or repressing transcription - is the crux of developmental or environmental control of gene expression. The book presents an up-to-date, critical overview of this rapidly advancing field.

📒Gene Regulation ✍ David S. Latchman

Gene Regulation Book PDF
✏Book Title : Gene Regulation
✏Author : David S. Latchman
✏Publisher : Garland Science
✏Release Date : 2002
✏Pages : 323
✏ISBN : 0748765301
✏Available Language : English, Spanish, And French

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✏Gene Regulation Book Summary : This lucid, well structured and jargon-free book provides an up-to-date and comprehensive account of the processes involved in gene expression and the mechanisms by which such expression is regulated. New information on how viruses modify host gene regulation has been included in this new edition. Methods used to analyze gene expression have also been given more attention, with a new section added on methods for examining DNA binding by transcriptional factors.

Structure Function Analysis Of The Eukaryotic Transcription Elongation Factor Tfiis Book PDF
✏Book Title : Structure function Analysis of the Eukaryotic Transcription Elongation Factor TFIIS
✏Author : Nell Belinda Shimasaki
✏Publisher :
✏Release Date : 1999
✏Pages : 484
✏ISBN : UCAL:C3442073
✏Available Language : English, Spanish, And French

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✏Structure function Analysis of the Eukaryotic Transcription Elongation Factor TFIIS Book Summary :

📒Gene Control ✍ David Latchman

Gene Control Book PDF
✏Book Title : Gene Control
✏Author : David Latchman
✏Publisher : Garland Science
✏Release Date : 2018-03-29
✏Pages : 448
✏ISBN : 9781136844201
✏Available Language : English, Spanish, And French

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✏Gene Control Book Summary : Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition. The first part of the book deals with the fundamental processes of gene control at the levels of chromatin structure, transcription, and post-transcriptional processes. Three pairs of chapters deal with each of these aspects, first describing the basic process itself, followed by the manner in which it is involved in controlling gene expression. The second part of the book deals with the role of gene control in specific biological processes. Certain chapters deal with the importance of gene control in cellular signaling processes and for normal development of the embryo. Another chapter discusses the key roles played by gene-regulatory processes in the specification of differentiated cell types such as muscle cells and neurons. The final chapters discuss the consequences of errors in gene control; the relationship between gene misregulation and human diseases, especially cancer; and potential therapies designed specifically to target particular levels of gene control. Gene Control will be of value to students in biological sciences, as well as to scientists and clinicians interested in how genes are regulated in health and disease.

📒Transcription Factors In Eukaryotes ✍ Athanasios Papavassiliou

Transcription Factors In Eukaryotes Book PDF
✏Book Title : Transcription Factors in Eukaryotes
✏Author : Athanasios Papavassiliou
✏Publisher : International Thomson Publishing Services
✏Release Date : 1997
✏Pages : 354
✏ISBN : 0412125013
✏Available Language : English, Spanish, And French

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✏Transcription Factors in Eukaryotes Book Summary : Incl. structure/function relationships of transcription factors in the context of cytoplasmic & nuclear milieus etc.

📒Mechanisms Of Transcription ✍ Fritz Eckstein

Mechanisms Of Transcription Book PDF
✏Book Title : Mechanisms of Transcription
✏Author : Fritz Eckstein
✏Publisher : Springer
✏Release Date : 2011-10-03
✏Pages : 327
✏ISBN : 3642645097
✏Available Language : English, Spanish, And French

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✏Mechanisms of Transcription Book Summary : Mechanisms of Transcription presents a unique perspective on the fundamental processes of transcription. A collection of distinguished authors draws together the underlying mechanisms involved in the process of transcription. This includes RNA polymerase function and its interaction with promoter sequences, and the structures of the various components on the transcriptional machinery. Both prokaryotic and eukaryotic systems, NMR and crystallographic structures of a number of important eukaryotic transcription factors are discussed, as well as the role of chromatin structure.

Photoaffinity Labeling Of Eukaryotic Transcription Complexes Book PDF
✏Book Title : Photoaffinity Labeling of Eukaryotic Transcription Complexes
✏Author : Blaine Bartholomew
✏Publisher :
✏Release Date : 1988
✏Pages : 372
✏ISBN : UCAL:X32844
✏Available Language : English, Spanish, And French

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✏Photoaffinity Labeling of Eukaryotic Transcription Complexes Book Summary :

Cryo Electron Microscopy Eukaryotic Transcription And Dna Repair Book PDF
✏Book Title : Cryo Electron Microscopy Eukaryotic Transcription and DNA Repair
✏Author : Wei-Hau Chang
✏Publisher :
✏Release Date : 2000
✏Pages : 398
✏ISBN : STANFORD:36105023674398
✏Available Language : English, Spanish, And French

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✏Cryo Electron Microscopy Eukaryotic Transcription and DNA Repair Book Summary :

📒Biochemistry 3e ✍ S. C. Rastogi

Biochemistry 3e Book PDF
✏Book Title : Biochemistry 3E
✏Author : S. C. Rastogi
✏Publisher : Tata McGraw-Hill Education
✏Release Date : 2010-04-01
✏Pages : 804
✏ISBN : 0070681759
✏Available Language : English, Spanish, And French

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✏Biochemistry 3E Book Summary : This thoroughly revised and updated third edition is designed to encompass the subject from basics to the latest developments. With the enhanced pedagogy and new contents, it offers an unparalleled exposure to biochemistry in a simple and coherent manner.

📒Gene Regulation In Eukaryotes ✍ Edgar Wingender

Gene Regulation In Eukaryotes Book PDF
✏Book Title : Gene Regulation in Eukaryotes
✏Author : Edgar Wingender
✏Publisher : Wiley-Blackwell
✏Release Date : 1993
✏Pages : 430
✏ISBN : UOM:39015029969725
✏Available Language : English, Spanish, And French

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✏Gene Regulation in Eukaryotes Book Summary : A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Dna Protein Interactions Book PDF
✏Book Title : DNA Protein Interactions
✏Author : A. Travers
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 192
✏ISBN : 9789401114806
✏Available Language : English, Spanish, And French

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✏DNA Protein Interactions Book Summary : Our understanding of the mechanisms regulating gene expression, which determine the patterns of growth and development in all living organisms, ultimately involves the elucidation of the detailed and dy namic interactions of proteins with nucleic acids -both DNA and RNA. Until recently the commonly presented view of the DNA double helix as visualized on the covers of many textbooks and journals - was as a monotonous static straight rod incapable in its own right of directing the processes necessary for the conservation and selective reading of genetic information. This view, although perhaps extreme, was reinforced by the necessary linearity of genetic maps. The reality is that the biological functions of both DNA and RNA are dependent on complex, and sometimes transient, three-dimensional nucleoprotein structures in which genetically distant elements are brought into close spatial proximity. It is in such structures that the enzymatic manipulation of DNA in the essential biological processes as DNA replication, transcription and recombination are effected - the complexes are the mediators of the 'DNA transactions' of Hatch Echols.

The Analysis Of Regulatory Dna Current Developments Knowledge And Applications Uncovering Gene Regulation Book PDF
✏Book Title : The Analysis of Regulatory DNA Current Developments Knowledge and Applications Uncovering Gene Regulation
✏Author : Kenneth Berendzen
✏Publisher : Bentham Science Publishers
✏Release Date : 2013-10-29
✏Pages : 225
✏ISBN : 9781608054923
✏Available Language : English, Spanish, And French

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✏The Analysis of Regulatory DNA Current Developments Knowledge and Applications Uncovering Gene Regulation Book Summary : A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteins, metabolites, RNA, various signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysis, prediction and discovery. The book also presents an overview of exploring gene regulatory networks, chromatin, and miRNAs. Information about state-of-the-art techniques for the determination of TF - cis-element interactions in vivo and in silico give cutting edge insights on how genomic-scale research is being approached. The Analysis of Regulatory DNA provides readers with both the necessary background knowledge and provocative, up-to-date insights aimed at sparking new and vibrant experimental designs for understanding and predicting cis-elements in the eukaryotic genome.

Transcription Factors Book PDF
✏Book Title : Transcription Factors
✏Author : S. Akira
✏Publisher : Springer Science & Business Media
✏Release Date : 2004-08-27
✏Pages : 581
✏ISBN : 3540210954
✏Available Language : English, Spanish, And French

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✏Transcription Factors Book Summary : With contributions by numerous experts

📒Transcription ✍ William M. Brown

Transcription Book PDF
✏Book Title : Transcription
✏Author : William M. Brown
✏Publisher : CRC Press
✏Release Date : 2001-09-20
✏Pages : 168
✏ISBN : 0415271991
✏Available Language : English, Spanish, And French

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✏Transcription Book Summary : Knowledge of transcription has moved forward at a furious pace over recent years, and an understanding of the processes involved in gene regulation and expression has become an essential element in biochemistry, genome biology, molecular biology and molecular genetics. In this timely book, the authors present an accessible, yet comprehensive, coverage suitable for students at a senior undergraduate level, and for postgraduates needing an overview of the current state of play. It covers a number of pertinent examples of transcription systems for eukaryotes and prokaryotes, indicates methods for studying transcription, and surveys the whole topic of transcription from many perspectives.

📒Cell Biology E Book ✍ Thomas D. Pollard

Cell Biology E Book Book PDF
✏Book Title : Cell Biology E Book
✏Author : Thomas D. Pollard
✏Publisher : Elsevier Health Sciences
✏Release Date : 2007-04-26
✏Pages : 928
✏ISBN : 9781437700633
✏Available Language : English, Spanish, And French

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✏Cell Biology E Book Book Summary : A masterful introduction to the cell biology that you need to know! This critically acclaimed textbook offers you a modern and unique approach to the study of cell biology. It emphasizes that cellular structure, function, and dysfunction ultimately result from specific macromolecular interactions. You'll progress from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. The exquisite art program helps you to better visualize molecular structures. Covers essential concepts in a more efficient, reader-friendly manner than most other texts on this subject. Makes cell biology easier to understand by demonstrating how cellular structure, function, and dysfunction result from specific macromole¬cular interactions. Progresses logically from an explanation of the "hardware" of molecules and cells to an understanding of how these structures function in the organism in both healthy and diseased states. Helps you to visualize molecular structures and functions with over 1500 remarkable full-color illustrations that present physical structures to scale. Explains how molecular and cellular structures evolved in different organisms. Shows how molecular changes lead to the development of diseases through numerous Clinical Examples throughout. Includes STUDENT CONSULT access at no additional charge, enabling you to consult the textbook online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles—to help you see the connections between diverse disciplines · test your knowledge with multiple-choice review questions · and more! New keystone chapter on the origin and evolution of life on earth probably the best explanation of evolution for cell biologists available! Spectacular new artwork by gifted artist Graham Johnson of the Scripps Research Institute in San Diego. 200 new and 500 revised figures bring his keen insight to Cell Biology illustration and further aid the reader’s understanding. New chapters and sections on the most dynamic areas of cell biology - Organelles and membrane traffic by Jennifer Lippincott-Schwartz; RNA processing (including RNAi) by David Tollervey., updates on stem cells and DNA Repair. ,More readable than ever. Improved organization and an accessible new design increase the focus on understanding concepts and mechanisms. New guide to figures featuring specific organisms and specialized cells paired with a list of all of the figures showing these organisms. Permits easy review of cellular and molecular mechanisms. New glossary with one-stop definitions of over 1000 of the most important terms in cell biology.

Genetic Engineering Principles And Methods 28 Book PDF
✏Book Title : Genetic Engineering Principles and Methods 28
✏Author : Jane K. Setlow
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-03-21
✏Pages : 190
✏ISBN : 9780387345048
✏Available Language : English, Spanish, And French

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✏Genetic Engineering Principles and Methods 28 Book Summary : This book, published by Springer since 1979, presents state-of-the-art discussions in modern genetics and genetic engineering. This focus affirms a commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Recent volumes have covered gene therapy research, genetic mapping, plant science and technology, transport protein biochemistry, and viral vectors in gene therapy, among other topics.

📒Transcription Factors ✍ Joseph Locker

Transcription Factors Book PDF
✏Book Title : Transcription Factors
✏Author : Joseph Locker
✏Publisher : Garland Science
✏Release Date : 2012-10-12
✏Pages : 352
✏ISBN : 9781135323639
✏Available Language : English, Spanish, And French

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✏Transcription Factors Book Summary : Transcription factors are important in regulating gene expression, and their analysis is of paramount interest to molecular biologists studying this area. This book looks at the basic machinery of the cell involved in transcription in eukaryotes and factors that control transcription in eukaryotic cells. It examines the regulatory systems that modulate gene expression in all cells,a s well as the more specialized systems that regulate localized gene expression throughout the mammalian organism. Transcription Factors updates classical knowledge with recent advances to provide a full and comprehensive coverage of the field for postgraduates and researchers in molecular biology involved in the study of gene regulation.

📒Dna Protein Interactions ✍ G. Geoff Kneale

Dna Protein Interactions Book PDF
✏Book Title : Dna Protein Interactions
✏Author : G. Geoff Kneale
✏Publisher : Springer Science & Business Media
✏Release Date : 1994
✏Pages : 427
✏ISBN : 9781592595174
✏Available Language : English, Spanish, And French

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✏Dna Protein Interactions Book Summary : The clear and easy-to-follow protocols collected here illuminate the molecular basis of protein-nucleic acid interactions. Use them successfully to reveal the location of the DNA binding site, the strength and specificity of a binding, the identities of individual groups on the actual bases involved in binding, and the specific amino acid residues of the protein that interact with the DNA. Some of the techniques can even be used to identify previously unknown DNA binding proteins from crude cell extracts, thus empowering you to make groundbreaking advances in your work.

📒Advances In Immunology ✍ Frederick W. Alt

Advances In Immunology Book PDF
✏Book Title : Advances in Immunology
✏Author : Frederick W. Alt
✏Publisher : Academic Press
✏Release Date : 2009-12-03
✏Pages : 184
✏ISBN : 008096303X
✏Available Language : English, Spanish, And French

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✏Advances in Immunology Book Summary : Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. * Contributions from leading authorities and industry experts * Informs and updates on all the latest developments in the field

Progress In Nucleic Acid Research And Molecular Biology Book PDF
✏Book Title : Progress in Nucleic Acid Research and Molecular Biology
✏Author :
✏Publisher : Academic Press
✏Release Date : 1998-06-02
✏Pages : 353
✏ISBN : 0080863485
✏Available Language : English, Spanish, And French

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✏Progress in Nucleic Acid Research and Molecular Biology Book Summary : Provides a forum for discussion of new discoveries, approaches and ideas in molecular biology Contributions from leaders in their fields Abundant references

📒Human Gene Evolution ✍ David Neil Cooper

Human Gene Evolution Book PDF
✏Book Title : Human Gene Evolution
✏Author : David Neil Cooper
✏Publisher : Elsevier
✏Release Date : 1999-11-17
✏Pages : 490
✏ISBN : 0121878708
✏Available Language : English, Spanish, And French

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✏Human Gene Evolution Book Summary : Presents the principles of human gene evolution in a concise and easy to understand fashion. Uses examples of how evolutionary processes have molded present day genes, drawn from the evolution of humans and other primates, as well as from more primitive organisms. With increasing attention in this expanding area, this review forms a timely publication of our current knowledge of this important field. Structure and function in the human genome The evolution of gene structure Mutational mechanisms in evolution

📒Gene Transcription ✍ R. J. White

Gene Transcription Book PDF
✏Book Title : Gene Transcription
✏Author : R. J. White
✏Publisher : John Wiley & Sons
✏Release Date : 2009-04-01
✏Pages : 288
✏ISBN : 9781444311365
✏Available Language : English, Spanish, And French

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✏Gene Transcription Book Summary : Transcription is the focus of much cutting-edge research, as befitsits essential place in biology. The established link betweendefects in gene transcription and many human disorders has fuelledconsiderable activity in the biomedical arena, particularly cancerresearch. This concentration of attention has uncovered a myriad offactors involved in transcription and the literature is now rifewith jargon and complexity. Gene Transcription: Mechanisms and Control aims todemystify the subject for a non-expert audience, providing a guidedtour around the complex machinery of the transcriptional apparatusand discussing how the various factors achieve their functions. Byfocusing on general principles and illustrating these with a selectgroup of examples, many of which are linked to human diseases, theauthor conveys the intricacies of transcriptional control in anaccessible manner. With the first chapter presenting an overview of geneexpression, this is a 'stand-alone' text, ideal for advanced levelundergraduates and postgraduates in biology, biochemistry andmedical sciences. It will also appeal to research scientists whorequire a broad current perspective on this rapidly moving andcomplex field. Provides a broad and accessible introduction to genetranscription. Up-to-date coverage of the major topics in a rapidly evolvingfield. Illustrates the links between aberrant transcription and humandisease. Explains the jargon associated with transcription factors.