Essentials of Stem Cell Biology

• Author : Robert Lanza,Anthony Atala
• Publisher : Academic Press
• Release : 31 October 2013

This book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation of the latest research information about specific organ systems. It covers a wide range of topics, including basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to the application of stem cells to specific human diseases, regulation and ethics, and patient perspectives.

• Author : Gabriela Rodrigues,Bernard A. J. Roelen
• Publisher : Springer
• Release : 01 July 2020

This textbook will support graduate students with learning materials rich in the basic concepts of stem cell biology, in its most widespread and updated perspective. The chapters are conceived in a way for students to understand the meaning of pluripotency, the definition of embryonic stem cells and the formation of multicellular structures such as organoids together with the underlying principles of their epigenetic. This textbook also discusses adult stem cells and the potential use of these cells, in particular neural,

• Author : Robert Lanza,John Gearhart,Brigid Hogan,Douglas Melton,Roger Pedersen,E. Donnall Thomas,James A. Thomson,Ian Sir Wilmut
• Publisher : Academic Press
• Release : 05 June 2009

First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing the latest advances in stem cells. Representing the combined effort of seven editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a

• Author : Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
• Publisher : John Wiley & Sons
• Release : 02 December 2015

This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues

• Author : Mary Clarke,Jonathan Frampton
• Publisher : Garland Science
• Release : 30 June 2022

"This book defines what constitutes a stem cell while making clear where there can be misunderstanding or confusion that leads to some non-stem cells being misrepresented. We will distinguish the basic stem cell types and how they are characterized, focusing on the sorts of experimental approaches employed, many of which have been specifically developed for the purpose of investigating these cells. At this point, it will be pertinent to consider the reasons why stem cells have become an important part

• Author : Shimon Efrat
• Publisher : Springer Science & Business Media
• Release : 01 December 2009

Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and

• Author : Jonathan Slack
• Publisher : OUP Oxford
• Release : 23 February 2012

The topic of stem cells has been very high profile in the media in recent years. There is much public interest in stem cells but also much confusion and misinformation, with some companies already offering 'stem cell products' and bogus 'stem cell therapies'. In this Very Short Introduction, Jonathan Slack introduces stem cells; what they are, what scientists do with them, what stem cell therapies are available today, and how they might be used in future. Despite important advances, clinical

• Author : Yanhong Shi,Dennis Clegg
• Publisher : Springer
• Release : 20 November 2010

This book is an updated reference for one of the most exciting field of biomedical researches- Stem Cell Research and its therapeutic applications. Stem cell research holds great promise for the treatment of many human diseases that currently lack effective therapies. The set of chapters in this book provide insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and li ver degeneration.

• Author : Alexander Birbrair
• Publisher : Springer
• Release : 23 April 2019

This book presents a comprehensive discussion on the novel concepts in stem cell heterogeneity, from pluripotent stem cells to human mesenchymal stem cells, adult and cancer stem cells of the thyroid, sarcoma, and more. Thus, Stem Cell Heterogeneity - Novel Concepts starts from a timely update on the current information on stem cells heterogeneity in various tissues and discusses new concepts and future directions. It also provides a solid foundation of the history of stem cells from specific tissues and

• Author : Jonathan M. W. Slack,Leslie Dale
• Publisher : John Wiley & Sons
• Release : 25 January 2022

Discover the foundations of developmental biology with this up to date and focused resource from two leading experts The newly revised Fourth Edition of Essential Developmental Biology delivers the fundamentals of the developmental biology of animals. Designed as a core text for undergraduate students in their first to fourth years, as well as graduate students in their first year, the book is suited to both biologically based and medically oriented courses. The distinguished authors presume no prior knowledge of development,

• Author : M. Fagan
• Publisher : Springer
• Release : 21 January 2013

This examination of stem cell biology from a philosophy of science perspective clarifies the field's central concept, the stem cell, as well as its aims, methods, models, explanations and evidential challenges. Relations to systems biology and clinical medicine are also discussed.

• Author : M.A. Hayat
• Publisher : Springer Science & Business Media
• Release : 22 February 2012

It is pointed out that a cancer stem cell is a type within a tumor that possesses the capacity of self-renewal and can give rise to the heterogeneous lineages of cancer cells, which comprise the tumor. It is emphasized that a unique feature of cancer stem cells is that, although conventional chemotherapy kills most cells in a tumor, cancer stem cells remain intact. Vast applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem

• Author : Barbara Zavan,Eriberto Bressan
• Publisher : Humana
• Release : 30 May 2018

This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications

• Author : Charles J. Malemud,Eben Alsberg
• Publisher : Springer
• Release : 10 December 2016

This essential volume explores mesenchymal stem cells (MSCs) and their potential to suppress immune-mediated inflammation. The chapters examine applications in autoimmune diseases such as lupus, rheumatoid arthritis and multiple sclerosis; blood cancers such as leukemia and lymphoma; and reproductive complications, specifically pre-term labor and use of MSCs in vitro and in animal models to discover methods of suppressing the causal inflammatory response. It also further defines the methodologies required to develop research on MSCs in vitro into established preclinical animal

• Author : Gregory R. Bock,Jamie A. Goode
• Publisher : John Wiley & Sons
• Release : 22 April 2005

Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on the important ethical issues that are raised by research on stem cells. They review the various regulatory regimes, which apply in different countries – a key factor in determining where future stem cell research is carried out. Potential clinical applications covered in the book