Epigenetics in Human Disease

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  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Pages : 704 pages
  • ISBN : 9780128122150
  • Rating : /5 from reviews
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Download or Read online Epigenetics in Human Disease full in PDF, ePub and kindle. this book written by Trygve Tollefsbol and published by Academic Press which was released on 01 June 2018 with total page 704 pages. We cannot guarantee that Epigenetics in Human Disease book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Epigenetics is one of the fastest growing fields in biomedical research, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. In Epigenetics in Human Disease, Second Edition, leading international researchers examine those diseases or conditions for which we have advanced knowledge of epigenetic mechanisms such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders, and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis, and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and data sets, early-life programming of epigenetics in age-related diseases, and epigenetics of addiction and suicide, as well as epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies. With its translational focus, Epigenetics in Human Disease, Second Edition, serves as an invaluable reference for both basic scientists and clinicians alike Includes contributions by leading international investigators involved in translational epigenetic research and therapeutic applications Integrates methods and applications with fundamental chapters on epigenetics in human disease, as well as evaluation of recent epigenetic clinical breakthroughs Side-by-side coverage of the basis of epigenetic diseases and treatment pathways This new edition has been fully revised to cover current developments in disease epigenetics, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and data sets, early-life programming of epigenetics in age-related diseases, and epigenetics of addiction and suicide, as well as epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies

Epigenetics in Human Disease

Epigenetics in Human Disease
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 01 June 2018
GET THIS BOOK Epigenetics in Human Disease

Epigenetics is one of the fastest growing fields in biomedical research, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. In Epigenetics in Human Disease, Second Edition, leading international researchers examine those diseases or conditions for which we have advanced knowledge of epigenetic mechanisms such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders, and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology,

Computational Epigenetics and Diseases

Computational Epigenetics and Diseases
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 06 February 2019
GET THIS BOOK Computational Epigenetics and Diseases

Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease,

Human Epigenetics How Science Works

Human Epigenetics  How Science Works
  • Author : Carsten Carlberg,Ferdinand Molnár
  • Publisher : Springer Nature
  • Release : 24 September 2019
GET THIS BOOK Human Epigenetics How Science Works

The view “It’s all in our genes and we cannot change it” developed in the past 150 years since Gregor Mendel’s experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates how and when they are used. In the cell nucleus our genes are packed into chromatin, which is a complex of histone proteins and genomic DNA, representing the molecular basis

Clinical Epigenetics

Clinical Epigenetics
  • Author : Luke B. Hesson,Antonia L. Pritchard
  • Publisher : Springer Nature
  • Release : 31 August 2019
GET THIS BOOK Clinical Epigenetics

In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics is relevant in a clinical context, and to implement epigenetic testing in diagnostic laboratories. The book begins with a historical perspective of genetics and epigenetics and describes the work of

Epigenetics and Complex Traits

Epigenetics and Complex Traits
  • Author : Anna K. Naumova,Celia M.T. Greenwood
  • Publisher : Springer Science & Business Media
  • Release : 17 September 2013
GET THIS BOOK Epigenetics and Complex Traits

This book will provide an overview of basic epigenetic phenomena; interaction between epigenetic and genetic factors; and the influence of epigenetic factors on inheritance. Epigenetic states may contribute to the penetrance of genetic polymorphisms or mutations and thereby modify inheritance patterns. This may result in non‐Mendelian inheritance of genetic traits such as observed in common human disease. The relationship between epigenetics and genetics, however, has not been comprehensively summarized yet. The topic is being more and more appreciated lately

Epigenetics of Infectious Diseases

Epigenetics of Infectious Diseases
  • Author : Walter Doerfler,Josep Casadesús
  • Publisher : Springer
  • Release : 26 May 2017
GET THIS BOOK Epigenetics of Infectious Diseases

The present volume of Epigenetics and Human Health is devoted to the patho-epigenetics of viral and microbial infections, an exiting new field of disease-related epigenetic research. As recognized during the past years, epigenetic reprogramming of pathogen and host genome functions – the latter frequently induced by pathogens – plays an important role in many infectious processes. Beyond their immediate relevance for pathogen proliferation and obligatorily associated symptoms, such alterations frequently contribute to severe additional complications, such as the development of immunodeficiency, cancer

Handbook of Epigenetics

Handbook of Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 10 July 2017
GET THIS BOOK Handbook of Epigenetics

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable epigenetic processes. These epigenetic processes range from DNA methylation to prions. The biological processes impacted by epigenetics are vast and encompass effects in lower organisms and humans that include tissue

Epigenetics Development and Disease

Epigenetics  Development and Disease
  • Author : Tapas Kumar Kundu
  • Publisher : Springer Science & Business Media
  • Release : 13 November 2012
GET THIS BOOK Epigenetics Development and Disease

Epigenetics fine-tunes the life processes dictated by DNA sequences, but also kick-starts pathophysiological processes including diabetes, AIDS and cancer. This volume tracks the latest research on epigenetics, including work on new-generation therapeutics.

Transgenerational Epigenetics

Transgenerational Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 15 August 2019
GET THIS BOOK Transgenerational Epigenetics

Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather reversible and heritable epigenetic processes. These processes may have selective or adverse effects on offspring persisting for multiple generations. Transgenerational Epigenetics, Second Edition offers the only up-to-date, comprehensive analysis of the inheritance of epigenetic phenomena between generations with emphasis on human disease relevance, drug discovery, and next steps in clinical translation. Here, international experts discuss mechanisms of epigenetic inheritance, its expression in

Epigenetics In Human Reproduction And Development

Epigenetics In Human Reproduction And Development
  • Author : Naumova Anna K,Taketo-hosotani Teruko
  • Publisher : World Scientific
  • Release : 20 December 2016
GET THIS BOOK Epigenetics In Human Reproduction And Development

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the

Epigenetics

Epigenetics
  • Author : Derek J. Chadwick,Gail Cardew
  • Publisher : John Wiley & Sons
  • Release : 30 April 2008
GET THIS BOOK Epigenetics

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated.

Epigenetics for Intermediate The Most Comprehensive Exploration of the Practical Social and Ethical Impact of DNA on Our Society and Our World

Epigenetics for Intermediate  The Most Comprehensive Exploration of the Practical  Social and Ethical Impact of DNA on Our Society and Our World
  • Author : Frank Brown
  • Publisher : Youcanprint
  • Release : 15 September 2021
GET THIS BOOK Epigenetics for Intermediate The Most Comprehensive Exploration of the Practical Social and Ethical Impact of DNA on Our Society and Our World

You Are About To Develop An Insider Understanding Of Epigenetics, Including Their Relationship With The DNA, Environmental Factors, Human Development And Evolution; Their Role In Human Mental And Physical Health, Including Their Use In The Treating Of Different Conditions And Diseases Along With The Most Current Epigenetic Practices And Research! What started as a broad research focused on combining genetics and developmental biology during the mid-twentieth century has evolved into the field we currently refer to as epigenetics- the mechanism

Epigenetics Traits in Mammalian Tissues From New Technology to New Hypotheses

Epigenetics Traits in Mammalian Tissues  From New Technology to New Hypotheses
  • Author : Michael E. Symonds,Rafael Franco
  • Publisher : Frontiers Media SA
  • Release : 23 September 2019
GET THIS BOOK Epigenetics Traits in Mammalian Tissues From New Technology to New Hypotheses

How with the same genome a neuron is so different from a muscle cell? In Eva Jablonka and Lamb’s words, "epigenetics is one of the four dimensions of evolution". Actually, epigenetics should anything which occur in living cells that cannot be only explained by the genes/genome. After decades thinking and acting as if the genome determined the absolute fate of any life form in Earth, the relevance of epigenetics for mammalian life, disease and death is now recognized.