Epigenetics And Reproductive Health

Epigenetics And Reproductive Health Book PDF
✏Book Title : Epigenetics and Reproductive Health
✏Author :
✏Publisher : Academic Press
✏Release Date : 2020-09-12
✏Pages : 444
✏ISBN : 9780128197547
✏Available Language : English, Spanish, And French

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✏Epigenetics and Reproductive Health Book Summary : Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Environmental Impacts On Reproductive Health And Fertility Book PDF
✏Book Title : Environmental Impacts on Reproductive Health and Fertility
✏Author : Tracey J. Woodruff
✏Publisher : Cambridge University Press
✏Release Date : 2010-01-28
✏Pages :
✏ISBN : 9781139484848
✏Available Language : English, Spanish, And French

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✏Environmental Impacts on Reproductive Health and Fertility Book Summary : Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Epigenetics And Human Reproduction Book PDF
✏Book Title : Epigenetics and Human Reproduction
✏Author : Sophie Rousseaux
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-11-03
✏Pages : 372
✏ISBN : 3642147739
✏Available Language : English, Spanish, And French

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✏Epigenetics and Human Reproduction Book Summary : Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Male Reproductive Health Book PDF
✏Book Title : Male Reproductive Health
✏Author : Wei Wu
✏Publisher : BoD – Books on Demand
✏Release Date : 2020-03-04
✏Pages : 202
✏ISBN : 9781789856477
✏Available Language : English, Spanish, And French

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✏Male Reproductive Health Book Summary : Male reproductive health is an important area affecting men's overall health and well-being. Infertility is a worldwide problem that affects approximately 15% of married couples. Half of these cases can be traced to male partners. Infertile men are at an elevated risk of cancer development later in life, primarily genitourinary malignancies such as testicular and prostate cancer. This book will focus on male reproductive health, from the aspects of semen quality, male infertility, testicular cancer, and prostate cancer, and their detection, diagnosis, treatment, and prevention.

📒Reproductive Health Psychology ✍ Olga B. A. van den Akker

Reproductive Health Psychology Book PDF
✏Book Title : Reproductive Health Psychology
✏Author : Olga B. A. van den Akker
✏Publisher : John Wiley & Sons
✏Release Date : 2012-03-23
✏Pages : 392
✏ISBN : 9781119968191
✏Available Language : English, Spanish, And French

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✏Reproductive Health Psychology Book Summary : This volume provides a comprehensive, up-to-date theoretical andempirical background to the psychology of reproductive health. Provides a life span perspective of the psychology ofreproductive health and its disorders, from menarche to menopauseand reproductive health in older age Focuses on issues of the individual's reproductive healthexperience, including reproduction, pregnancy, maternity, andbirth, as well as conditions such as PMDD, dysmenorrhea, and eventsincluding pregnancy failure, and abortion Acknowledges the wider social context with discussions ofpoverty, inequality, educational and economic status, age, andurban versus rural access Addresses life style related factors, human rights to choice,information and access, fertility control and reproductive healthregulation and health care services Illustrates topics with empirical data supported with tablesand figures

📒Epigenetics And Human Health ✍ Alexander Haslberger

Epigenetics And Human Health Book PDF
✏Book Title : Epigenetics and Human Health
✏Author : Alexander Haslberger
✏Publisher : John Wiley & Sons
✏Release Date : 2011-08-24
✏Pages : 316
✏ISBN : 9783527644759
✏Available Language : English, Spanish, And French

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✏Epigenetics and Human Health Book Summary : After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.

Optimizing Women S Health Through Nutrition Book PDF
✏Book Title : Optimizing Women s Health through Nutrition
✏Author : Lilian U. Thompson
✏Publisher : CRC Press
✏Release Date : 2007-12-03
✏Pages : 472
✏ISBN : 1420043013
✏Available Language : English, Spanish, And French

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✏Optimizing Women s Health through Nutrition Book Summary : It is no surprise that women and men experience biological and physiological differences fundamentally and throughout the lifecycle. What is surprising is that faced with such a self-evident truth, there should be so little consideration to date of how these differences affect susceptibility to disease and metabolic response to dietary treatment. Understanding these differences and developing a gender-based approach focusing on the specific needs and conditions of women is crucial to achieve effective nutritional strategies for women’s health. Expanding the knowledge-base regarding sex, nutrition, and medicine, Optimizing Women’s Health through Nutrition presents the biology, physiology, and metabology unique to women. The book demonstrates in a practical, accessible manner the scientific application of this data addressing lifecycle changes, disease prevention, and treatment. Based on sound research and supported by extensive references, it begins by describing recent research on biological and physiological differences and how these differences translate into varying disease trends between the sexes. Contributions describe the nutritional needs of women during the lifecycle, particularly during adolescence, pregnancy and lactation, premenopause, and menopause and midlife stages. The bulk of the book addresses each of the common major diseases or conditions that specifically affect the health of women. It emphasizes the role of nutrition in disease risk reduction as well as management and treatment of disease. Specific disease selection was dictated by those in which women are more vulnerable or have a higher incidence than men. The concluding section identifies areas for future research and strategic areas of investigation for researchers and health professionals, government regulators, and food industry professionals involved in creating novel foods that enhance women’s health.

📒Epigenetics And Cancer ✍ Fazlul H. Sarkar

Epigenetics And Cancer Book PDF
✏Book Title : Epigenetics and Cancer
✏Author : Fazlul H. Sarkar
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-05-29
✏Pages : 287
✏ISBN : 9789400766129
✏Available Language : English, Spanish, And French

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✏Epigenetics and Cancer Book Summary : Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role of epigenetic deregulation of microRNAs (miRNAs) and their target mRNAs along with epigenetic deregulation of mRNAs. This book also illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in modulating the epigenetic reprogramming of miRNAs and mRNAs for the prevention and/or treatment of human malignancies. It is well known that genetic aberrations, especially inherited through parents (somatic genetic alterations) contribute to the development of less than 10% of all cancer yet epigenetic alterations in genes especially through selective methylation and acetylation appears to be responsible for the development and progression of the vast majority of all cancers. Therefore, understanding the role of epigenetics in the regulation of genes especially through deregulated expression of miRNAs as presented in this book will allow scientists to devise targeted therapeutic strategies for re-expression of the lost genes or down-regulate the genes that are over-expressed in order to eradicate cancer. It is hoped that targeting epigenetics will not only target cancer cells but it will also target the tumor microenvironment (more like the entire tumor environment such as the entire host) for achieving better treatment outcomes for patients diagnosed with cancer which will lead to achieve the long-term objective for complete eradication of cancer. This book contains fifteen chapters which begins with the concept of systems and network biology for investigating the epigenetics of cancer followed by a series of articles on the role of miRNAs and their target genes in the biology of pancreatic cancer and other cancers such as breast, kidney, prostate and and colon. Since it is becoming increasingly clear that cancer stem cells (CSCs) are important in the development and progression of cancer, and CSCs are important in therapeutic resistance, treatment failure and tumor recurrence, thus the importance of CSCs and epigenetics has been highlighted by a very timely article on epigenetic variations of stem cell markers in cancer including miRNAs. Moreover, just targeting heterogeneous cancer cell populations may not be optimal to eradicate tumors and for which one must take a holistic approach for developing drugs that could also target the tumor microenvironment and tumor dormancy that are regulated through epigenetics. Keeping abreast with this thought process the concluding chapter provides a concept towards curative cancer therapy with maspin, which could be a unique window of opportunity to target tumor dormancy. Therefore, it suggest that targeting the tumor dormancy and the tumor microenvironment using novel therapeutics specifically by targeting epigenetics would become the future of medicine.

Knobil And Neill S Physiology Of Reproduction Book PDF
✏Book Title : Knobil and Neill s Physiology of Reproduction
✏Author : Tony M. Plant
✏Publisher : Academic Press
✏Release Date : 2014-11-15
✏Pages : 2684
✏ISBN : 9780123977694
✏Available Language : English, Spanish, And French

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✏Knobil and Neill s Physiology of Reproduction Book Summary : The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context. The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field. Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction. Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.

Routledge International Handbook Of Women S Sexual And Reproductive Health Book PDF
✏Book Title : Routledge International Handbook of Women s Sexual and Reproductive Health
✏Author : Jane M. Ussher
✏Publisher : Routledge
✏Release Date : 2019-09-23
✏Pages : 614
✏ISBN : 9781351035613
✏Available Language : English, Spanish, And French

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✏Routledge International Handbook of Women s Sexual and Reproductive Health Book Summary : The Routledge International Handbook of Women’s Sexual and Reproductive Health is the authoritative reference work on important, leading-edge developments in the domains of women’s sexual and reproductive health. The handbook adopts a life-cycle approach to examine key milestones and events in women’s sexual and reproductive health. Contributors drawn from a range of disciplines, including psychology, medicine, nursing and midwifery, sociology, public health, women’s studies, and indigenous studies, explore issues through three main lenses: the biopsychosocial model feminist perspectives international, multidisciplinary perspectives that acknowledge the intersection of identities in women’s lives. The handbook presents an authoritative review of the field, with a focus on state-of-the-art work, encouraging future research and policy development in women’s sexual and reproductive health. Finally, the handbook will inform health care providers about the latest research and clinical developments, including women’s experiences of both normal and abnormal sexual and reproductive functions. Drawing upon international expertise from leading academics and clinicians in the field, this is essential reading for scholars and students interested in women’s reproductive health.

📒Epigenetics And Assisted Reproduction ✍ Cristina Camprubí

Epigenetics And Assisted Reproduction Book PDF
✏Book Title : Epigenetics and Assisted Reproduction
✏Author : Cristina Camprubí
✏Publisher :
✏Release Date : 2019
✏Pages :
✏ISBN : 1351804456
✏Available Language : English, Spanish, And French

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✏Epigenetics and Assisted Reproduction Book Summary :

Textbook Of Human Reproductive Genetics Book PDF
✏Book Title : Textbook of Human Reproductive Genetics
✏Author : Karen Sermon
✏Publisher : Cambridge University Press
✏Release Date : 2014-04-10
✏Pages : 200
✏ISBN : 9781107683587
✏Available Language : English, Spanish, And French

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✏Textbook of Human Reproductive Genetics Book Summary : This book brings together genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

📒Nutrition In Epigenetics ✍ Mihai D. Niculescu

Nutrition In Epigenetics Book PDF
✏Book Title : Nutrition in Epigenetics
✏Author : Mihai D. Niculescu
✏Publisher : John Wiley & Sons
✏Release Date : 2011-03-25
✏Pages : 332
✏ISBN : 0470959800
✏Available Language : English, Spanish, And French

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✏Nutrition in Epigenetics Book Summary : The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics reviews the latest research looking at the interaction between genes and nutrients and the role they play together in maintaining human health. Nutrition in Epigenetics is divided into two primary parts. The first part provides key principles such as epigenetic mechanisms, developmental epigenetics, and the role of epigenetics in disease. The second part looks specifically at the application of epigenetics to the field of human nutrition. Chapters review the role of specific nutrients in modulating epigenetic status and the effect on health and disease. Nutrition in Epigenetics is an indispensable resource for researchers, professionals and advanced students with an interest in human nutrition, epigenetics, and biomedical research.

Epigenetics In Health And Disease Book PDF
✏Book Title : Epigenetics in Health and Disease
✏Author : Igor Kovalchuk
✏Publisher : FT Press
✏Release Date : 2012
✏Pages : 598
✏ISBN : 9780132597081
✏Available Language : English, Spanish, And French

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✏Epigenetics in Health and Disease Book Summary : "After reviewing the field's history and context, the authors introduce and explain each key epigenetic mechanism. Next, they extensively discuss the roles these mechanisms may play in inheritance, development, health and disease, behavior, evolution, ecology, and the interactions of individual organisms with their environments"--Cover, p. [4].

Issues In Reproductive Medicine Research 2011 Edition Book PDF
✏Book Title : Issues in Reproductive Medicine Research 2011 Edition
✏Author :
✏Publisher : ScholarlyEditions
✏Release Date : 2012-01-09
✏Pages : 1035
✏ISBN : 9781464965142
✏Available Language : English, Spanish, And French

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✏Issues in Reproductive Medicine Research 2011 Edition Book Summary : Issues in Reproductive Medicine Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Reproductive Medicine Research. The editors have built Issues in Reproductive Medicine Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Reproductive Medicine Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Reproductive Medicine Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

📒Annual Review Of Nursing Research Volume 29 ✍ Ginette A. Pepper, PhD, RN, FAAN

Annual Review Of Nursing Research Volume 29 Book PDF
✏Book Title : Annual Review of Nursing Research Volume 29
✏Author : Ginette A. Pepper, PhD, RN, FAAN
✏Publisher : Springer Publishing Company
✏Release Date : 2012-05-29
✏Pages : 400
✏ISBN : 9780826157553
✏Available Language : English, Spanish, And French

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✏Annual Review of Nursing Research Volume 29 Book Summary : This landmark annual review has provided three decades of knowledge, insight, and research on topics critical to the continued advancement of the nursing profession. This latest edition is a compilation of the most significant nursing research in genetics and genomics. Articles have been carefully selected by the editors, highly respected scholars and researchers in the field of genetics, to bring together current research that has particular relevance for translation into a clinical setting or expansion into other research areas. The review provides authoritative information of the highest caliber not only to researchers, but also to clinicians and undergraduate and graduate nursing students. Key Topics: The current status of genomic molecular science Ethical, legal, and social issues in genomics Genetics of diseases and symptoms Genomics across the lifespan

Environmental Epigenomics In Health And Disease Book PDF
✏Book Title : Environmental Epigenomics in Health and Disease
✏Author : Randy L Jirtle
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-05-16
✏Pages : 302
✏ISBN : 9783642233807
✏Available Language : English, Spanish, And French

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✏Environmental Epigenomics in Health and Disease Book Summary : There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs are established as stem cell differentiate during embryogenesis, and they are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and also potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this book is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome.

📒Reproductive And Perinatal Epidemiology ✍ Statistics Germaine M. Buck Louis Director and Senior Investigator of the Division of Epidemiology, and Prevention Research (DESPR) Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) National Institutes of Health (NIH)

Reproductive And Perinatal Epidemiology Book PDF
✏Book Title : Reproductive and Perinatal Epidemiology
✏Author : Statistics Germaine M. Buck Louis Director and Senior Investigator of the Division of Epidemiology, and Prevention Research (DESPR) Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) National Institutes of Health (NIH)
✏Publisher : Oxford University Press, USA
✏Release Date : 2011-03-23
✏Pages : 360
✏ISBN : 9780199857746
✏Available Language : English, Spanish, And French

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✏Reproductive and Perinatal Epidemiology Book Summary : Population growth and global health disparities for many reproductive and perinatal outcomes are but a few of the pressing issues facing public health today. Despite growing interest in the field, formal training in reproductive and perinatal epidemiology remains limited, with few available textbooks aimed at providing an overview of the field. In response to this need, faculty from the Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD) and CIHR's Institute of Human Development, Child and Youth Health (IHDCYH) developed an intensive, competitive, Summer Institute in Reproductive and Perinatal Epidemiology. The curriculum of this Summer Institute has been developed into a textbook to provide students and researchers with a working knowledge of the substantive and methodologic issues underlying reproductive and perinatal epidemiology. Reproductive and Perinatal Epidemiology offers a core curriculum that addresses the epidemiology of major reproductive and perinatal outcomes. From human fecundity to birth and neonatal outcomes, the subject is approached from as international a perspective as possible, and the unique methodologic issues underlying each outcome are discussed. Developed by leading researchers in collaboration with their students in response to their needs and concerns, this is the definitive textbook on the subject.

Transgenerational And Epigenetic Effects Of Developmental Exposure To Atrazine On Medaka Oryzias Latipes  Book PDF
✏Book Title : Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka Oryzias Latipes
✏Author : Jacob Alexander Cleary
✏Publisher :
✏Release Date : 2018
✏Pages : 57
✏ISBN : OCLC:1120743006
✏Available Language : English, Spanish, And French

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✏Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka Oryzias Latipes Book Summary : "Exposure to environmental chemicals can cause epigenetic transgenerational inheritance of altered phenotypes. Chemicals such as the plasticizer bisphenol-A (BPA), the fungicidal vinclozolin, and the oral contraceptive component 17a-ethinylestradiol (EE2) induce epigenetic changes in various species. Each of these chemicals is an environmentally pervasive endocrine disrupting compound, as is the case with the abundantly used herbicide atrazine, whose endocrine disrupting mechanisms still remain unclear. Atrazine (ATZ) is presently one of the most abundantly used herbicides in the United States, and a common contaminant of natural water bodies and drinking waters in high-use areas. ATZ belongs to the triazine herbicides which specifically target photosynthetic tissues, yet ATZ can affect animal health. Fish exposed to ATZ and EE2 display dysregulation of reproductive processes, which include alterations to the hypothalamic-pituitary-gonadal (HPG) axis pathways. However, the potential for ATZ-induced transgenerational inheritance of reproductive dysfunction has not been investigated in fish. The transgenerational reproductive consequences of ATZ exposure have been explored in rats, but fish are among the species at greatest risk from ATZ exposure, therefore, I chose a model species to represent this environmentally relevant scenario. In the present study I analyzed the effects of ATZ and EE2 exposures during early development on transgenerational reproductive dysregulation in Japanese medaka (Oryzias latipes). F0 medaka were exposed to ATZ, EE2, and a solvent during the first twelve days of development with no exposure over the subsequent three generations. These early developmental exposures overlap with the critical windows of embryonic germ cell development, gonadogenesis, and sex determination when gonadal DNA methylation is being reprogrammed. Exposed males and females of the F0 treatment lineages were bred to produce the F1 generation, the F1 offspring were bred to produce the F2 generation, and the F2 offspring were bred to produce the F3 generation. Neither ATZ nor EE2 altered sperm parameters, gonadosomatic, or hepatosomatic indices in the treated F0 generation. However, the hepatosomatic index was reduced in F2 females derived from F0 fish treated with either ATZ or EE2. Hepatosomatic and gonadosomatic indices are ratios of liver and gonad weights to the total weight of the fish, which are cursory metrics for evaluating energetic and reproductive health. The fecundity of F0 and F2 fish was unaffected by exposure to ATZ or EE2; however, the fertilization rate was decreased among the F2 fish derived from the low ATZ and low EE2 treated F0 generation. Moreover, there were significant transgenerational differences in the expression of reproductive regulatory genes and genes required for DNA methylation. Genomic methylation patterns are catalyzed by DNA methyltransferase enzymes (dnmts) that regulate the heritable transcriptional activity of specific regions of DNA essential to development. Present results suggest that early life exposure to ATZ and EE2 cause no significant effects in the immediate generation, but that future generations of fish are at greater risk of reproductive dysfunction."--Abstract from author supplied metadata.

Dna Methylation Epigenetics And Metastasis Book PDF
✏Book Title : DNA Methylation Epigenetics and Metastasis
✏Author : Manel Esteller
✏Publisher : Springer Science & Business Media
✏Release Date : 2006-03-30
✏Pages : 310
✏ISBN : 9781402036422
✏Available Language : English, Spanish, And French

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✏DNA Methylation Epigenetics and Metastasis Book Summary : This book provides a broad and rich outline of the epigenetic mechanisms involved in cancer progression and the generation of metastasis. It describes the tumor suppressor genes undergoing transcriptional silencing by CpG island promoter hypermethylation in the different tumor types of the human anatomy and their association with tumoral behaviour. It also provides a comprehensive insightful look at the molecular players involved in DNA methylation, histone modification and chromatin remodelling complexes causing epigenetic lesions linked to the metastasic phenotypes. Finally, it explains how epigenetic lesions associated with cancer spreading can be targeted using new and potent chemotherapy drugs. The book is a state-of-the-art reference to all scientific researchers and clinicians interested in the understanding of the biological processes leading to tumor dissemination and to those that are keen to translate this knowledge to a better management of cancer patients. Each contributor is a specialist in their epigenetic area and their joint effort has created a unique view of the DNA methylation, histone and chromatin changes that define cancer metastasis.

📒Epigenetic Markers ✍ M. Widschwendter

Epigenetic Markers Book PDF
✏Book Title : Epigenetic Markers
✏Author : M. Widschwendter
✏Publisher : IOS Press
✏Release Date : 2007
✏Pages : 137
✏ISBN : 1586037226
✏Available Language : English, Spanish, And French

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✏Epigenetic Markers Book Summary : DNA methylation is an epigenetic process that occurs when a methyl group binds to one of DNA's four bases, cytosine. These changes are responsible for controlling the activity of genes by turning them off. This book contains ten articles that explore the details and challenges of cancer epigenetics.

Paternal Influences On Human Reproductive Success Book PDF
✏Book Title : Paternal Influences on Human Reproductive Success
✏Author : Douglas T. Carrell
✏Publisher : Cambridge University Press
✏Release Date : 2013-04-11
✏Pages :
✏ISBN : 9781107355071
✏Available Language : English, Spanish, And French

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✏Paternal Influences on Human Reproductive Success Book Summary : Historically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesis. Recent advances in genetic and epigenetic techniques have identified key mechanisms by which the sperm, and the DNA carried by the sperm, can affect early embryonic development. Paternal Influences on Human Reproductive Success examines the genetic and epigenetic influences on embryogenesis, as well as practical clinical factors related to the male contribution to reproductive success. It also provides 'cutting edge' data and analysis of recent evaluations of the role of advanced paternal age, environmental influences and lifestyle factors on male reproductive fitness, making this an invaluable text for physicians treating patients for infertility, recurrent pregnancy loss, and developmental anomalies, as well as basic scientists studying embryogenesis and spermatogenesis.

Epigenetics In Cancer Prevention Book PDF
✏Book Title : Epigenetics in Cancer Prevention
✏Author : Mukesh Verma
✏Publisher :
✏Release Date : 2003
✏Pages : 330
✏ISBN : UVA:X004686584
✏Available Language : English, Spanish, And French

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✏Epigenetics in Cancer Prevention Book Summary : This volume addresses the question of how knowledge of epigenetic phenomena like DNA methylation and acetylation can be applied to early cancer detection and risk assessment. The objectives of the papers include defining the terminology used in epigenetics.

Fanaroff And Martin S Neonatal Perinatal Medicine E Book Book PDF
✏Book Title : Fanaroff and Martin s Neonatal Perinatal Medicine E Book
✏Author : Richard J. Martin
✏Publisher : Elsevier Health Sciences
✏Release Date : 2010-10-04
✏Pages : 2008
✏ISBN : 9780323081115
✏Available Language : English, Spanish, And French

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✏Fanaroff and Martin s Neonatal Perinatal Medicine E Book Book Summary : Fanaroff and Martin’s Neonatal-Perinatal Medicine covers everything you need to improve the quality of life and long-term outcomes of your patients. Drs. Richard J. Martin, Avroy A. Fanaroff, and Michele C. Walsh, along with a multi-disciplinary team of contributors guide you through the sweeping developments in diagnosis and treatment of the mother fetus, and neonate. The completely updated 9th edition keeps you current on the late preterm infant, the fetal origins of adult disease, neonatal anemia, genetic disorders, and more. Get comprehensive guidance on treating patients through a dual focus on neonatology and perinatology. See nuances and details in over 800 illustrations that depict disorders in the clinical setting and explain complex information. Find the information you need easily with indexing in both volumes that provides quick access to specific guidance. Spot genetic problems early and advise parents of concerns thanks to completely new section on this topic. Tackle the health problems associated with preterm births through a new chapter on The Late Preterm Infant. Understand the fetal origins of adult disease through a new chapter that focuses on conditions that originate in the womb. Stay current on the developments and research surrounding neonatal anemia from the entirely new chapter on Blood and Hematopoietic System highlights. Obtain more global perspectives and best practices from an increased number of international contributions in this edition.

Reproductive Endocrinology And Infertility Book PDF
✏Book Title : Reproductive Endocrinology and Infertility
✏Author : Douglas T. Carrell
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-03-23
✏Pages : 826
✏ISBN : 1441914366
✏Available Language : English, Spanish, And French

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✏Reproductive Endocrinology and Infertility Book Summary : Management of the modern reproductive endocrinology and infertility clinic has become very complex. In addition to the medical and scientific aspects, it is crucial that the modern director be aware of of incongruent fields such as marketing, accounting, management, and regulatory issues. Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice was developed to assist the practicing reproductive endocrinologist and/or laboratory director by providing an overview of relevant scientific, medical, and management issues in a single volume. Experts in all pertinent areas present concise, practical, evidence-based summaries of relevant topics, producing a key resource for physicians and scientists engaged in this exciting field of medicine. As novel technologies continue to amplify, Reproductive Endocrinology and Infertility: Integrating Modern Clinical and Laboratory Practice offers insight into development, and imparts extra confidence to practitioners in handling the many demands presented by their work.

Handbook Of Diet And Nutrition In The Menstrual Cycle Periconception And Fertility Book PDF
✏Book Title : Handbook of diet and nutrition in the menstrual cycle periconception and fertility
✏Author : Caroline J. Hollins-Martin
✏Publisher : Wageningen Academic Publishers
✏Release Date : 2014-01-15
✏Pages : 568
✏ISBN : 9789086867677
✏Available Language : English, Spanish, And French

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✏Handbook of diet and nutrition in the menstrual cycle periconception and fertility Book Summary : The reproductive cycle in women is complex and can be considered to begin with epigenetic programming and ending with menopause. Intervening steps involve a variety of processes, including the cellular development of the sex organs, menarche, episodic endocrine cycles, menstruation, ovulation and conception. These processes can be influenced by diet and nutrition and vice versa. Body composition has an impact on the menstrual cycle and periconception and these factors in turn also influence body composition. Similarly, either food deprivation, dietary excess or obesity can result in marked changes in the menstrual cycle with a concomitant effect on fertility. This handbook is the first scientific source that provides a comprehensive overview of the relationship of diet and nutrition with puberty, menarche and menstrual cycle, conception and fertility and infertility. The handbook of diet and nutrition in the menstrual cycle, conception and fertility will benefit dieticians, nutritionists, gynaecologists, endocrinologists, obstetricians, paediatricians and those concerned with women's health in general.

Current Management Of Male Infertility An Issue Of Urologic  Book PDF
✏Book Title : Current Management of Male Infertility An Issue of Urologic
✏Author : Craig S Niederberger
✏Publisher : Elsevier Health Sciences
✏Release Date : 2014-02-09
✏Pages : 784
✏ISBN : 9780323266871
✏Available Language : English, Spanish, And French

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✏Current Management of Male Infertility An Issue of Urologic Book Summary : Current Management of Male Infertility, An Issue of Urologic,

Epigenetics In Human Reproduction And Development Book PDF
✏Book Title : Epigenetics In Human Reproduction And Development
✏Author : Naumova Anna K
✏Publisher : World Scientific
✏Release Date : 2016-12-20
✏Pages : 304
✏ISBN : 9789813144286
✏Available Language : English, Spanish, And French

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✏Epigenetics In Human Reproduction And Development Book Summary : Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

📒Transgenerational Epigenetics ✍ Trygve Tollefsbol

Transgenerational Epigenetics Book PDF
✏Book Title : Transgenerational Epigenetics
✏Author : Trygve Tollefsbol
✏Publisher : Elsevier
✏Release Date : 2014-05-02
✏Pages : 412
✏ISBN : 9780124059221
✏Available Language : English, Spanish, And French

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✏Transgenerational Epigenetics Book Summary : Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations. This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research. Focused discussion of metabolic disorders, cardiovascular diseases and longevity, which appear most affected by reversible and heritable epigenetic processes Encompasses both foundational and clinical aspects including discussions of preventative in utero therapies Covers history, future outlook, disease management and current controversies

A Life Course Approach To Healthy Ageing Book PDF
✏Book Title : A Life Course Approach to Healthy Ageing
✏Author : Diana Kuh
✏Publisher : OUP Oxford
✏Release Date : 2013-12-19
✏Pages : 288
✏ISBN : 9780191008184
✏Available Language : English, Spanish, And French

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✏A Life Course Approach to Healthy Ageing Book Summary : Healthy ageing has long been a neglected area of epidemiological research as the traditional focus has been on specific chronic diseases of older life. There is a growing consensus from scientists, research funders and policy makers that ageing itself needs to be studied from an interdisciplinary and life course perspective, to inform strategies for reducing the societal and individual costs of an ageing population. A Life Course Approach to Healthy Ageing is a synthesis of life course perspectives in epidemiology and interdisciplinary perspectives in ageing research. It brings together expert investigators of maturing birth cohort and ageing studies, cross-cutting methodologists, and authorities in ageing research and knowledge transfer from across the world in one wide-ranging volume. Contributors discuss how aspects of healthy ageing are conceptualised, defined and measured; relate to each other; change across life; and are influenced by biological, psychological and social factors operating from early life onwards. They identify research gaps, and suggest how evidence from observational studies can be strengthened through improved study design and longitudinal analysis, thereby increasing the research contribution to practice or policy change. The book considers how we might delay or slow down the progressive, generalised impairment of function that occurs at the individual, body system and cellular levels, as people grow older. It also considers the determinants of wellbeing in older people, including personal fulfilment, positive emotions and social relationships. Broad in scope, discussing topics from genetics to psychological and social wellbeing, A Life Course Approach to Healthy Ageing is a key resource for epidemiologists, social scientists, clinicians, public health physicians, policy makers and practitioners with a research interest in healthy ageing.