Epigenetic Regulation in the Nervous System

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  • Author : J. David Sweatt
  • Publisher : Academic Press
  • Pages : 374 pages
  • ISBN : 0123944058
  • Rating : /5 from reviews
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Download or Read online Epigenetic Regulation in the Nervous System full in PDF, ePub and kindle. this book written by J. David Sweatt and published by Academic Press which was released on 31 December 2012 with total page 374 pages. We cannot guarantee that Epigenetic Regulation in the Nervous System book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcomes. By understanding the molecular mechanisms involved in epigenetic modulation, researchers may be able to develop targeted therapies for those individuals in whom it malfunctions. Edited by the most highly regarded leaders in the field, this book offers a comprehensive review of behavioral epigenetics and a balanced treatment of the strengths and weaknesses in experimentation in this area. Covering background material as well as topics of current interest, it serves both as a cutting-edge resource and a foundational reference. The book will benefit neuroscience researchers and graduate students with an interest in the links between gene regulation and behavior, as will clinicians dealing with disorders such as addiction, depression, and schizophrenia. BMA Medical Book Awards 2014 - Highly Commended, Neurology, British Medical Association BMA Medical Book Awards 2014 - First Prize, Neurology, British Medical Association 2013 PROSE Award winner for Best in Reference Works and Best Single Volume Reference in Science from the Association of American Publishers Presents a unified view of epigenetic mechanisms from behavior to genes and everything in between Discusses clinically relevant disorders in the context of epigenetics research, making the volume appealing to clinicians as well as basic scientists Provides numerous practical examples for the new investigator to facilitate implementation of research in neuroepigenetics

Epigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System
  • Author : J. David Sweatt,Michael J. Meaney,Eric J. Nestler,Schahram Akbarian
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOK Epigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter

Epigenetic Mechanisms in Neural Plasticity

Epigenetic Mechanisms in Neural Plasticity
  • Author : Daniel Ortuño-Sahagún,Reinhard Schliebs,Merce Pallàs
  • Publisher : Frontiers Media SA
  • Release : 20 September 2019
GET THIS BOOK Epigenetic Mechanisms in Neural Plasticity

Neural plasticity is a unique and adaptive feature of nervous system, which allows neurons to reorganize their interactions in response to a stimulation (intrinsic or extrinsic) to maintain their function. For these reasons, epigenetics emerges as a potential field for developing strategies to modulate changes in pathological situation because extrinsic factors and pharmacological tools can modify neural functioning in organisms during their life. Diet, exercise, environmental aspects, stressors or drugs are available to alter those mechanisms. Epigenetic involves certain molecular

Epigenetic Mechanisms in the Brain

Epigenetic Mechanisms in the Brain
  • Author : Andrew J. Kennedy,Gabriella N. L. Chua
  • Publisher : Academic Press
  • Release : 01 June 2020
GET THIS BOOK Epigenetic Mechanisms in the Brain

Epigenetic mechanisms are the biological processes that determine how our genome is used and the same principle can be applied to our neuron genes. In recent findings in the field of neuroepigenetics, it has been determined that our genes encode our memories, transmit information about stressful events, and play apart in our addictions. This book helps to unlock these abstract processes, leading to improved individualized treatments.

Epigenetics Brain and Behavior

Epigenetics  Brain and Behavior
  • Author : Paolo Sassone Corsi,Yves Christen
  • Publisher : Springer Science & Business Media
  • Release : 19 October 2012
GET THIS BOOK Epigenetics Brain and Behavior

Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. A variety of studies have centered on the molcular mechanisms implicated in epigentic control and how these may operte in concert. It will be critical to unravel how specifity is achieved. The

Epigenetic Mechanisms in the Brain

Epigenetic Mechanisms in the Brain
  • Author : Andrew J. Kennedy,Gabriella N.L. Chua
  • Publisher : Academic Press
  • Release : 01 December 2022
GET THIS BOOK Epigenetic Mechanisms in the Brain

Epigenetic Mechanisms in the Brain provides recent findings in the field of neuroepigenetics, covering how our genes encode our memories, transmit information about stressful events, and play a part in our addictions. This book helps to unlock these abstract processes, with a forward goal of improving individualized treatments. Discusses how the epigenome affects long-term memory, stress and addiction Reviews the concept of transgenerational memory Describes treatment options for the epigenome

Brain Behavior and Epigenetics

Brain  Behavior and Epigenetics
  • Author : Arturas Petronis,Jonathan Mill
  • Publisher : Springer Science & Business Media
  • Release : 19 May 2011
GET THIS BOOK Brain Behavior and Epigenetics

Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of

Epigenetic Markers in the Postnatal Developing Rat Brain

Epigenetic Markers in the Postnatal Developing Rat Brain
  • Author : Rebecca Kaye Simmons
  • Publisher : Unknown
  • Release : 17 September 2021
GET THIS BOOK Epigenetic Markers in the Postnatal Developing Rat Brain

Epigenetic mechanisms provide a critical and plausible mechanism by which genes and the environment can interact and have been implicated in a number of diseases and disorders. In order to better understand how epigenetic mechanisms go awry in a diseased brain we must first understand how epigenetic mechanisms unfold during normal development. The present body of work begins to examine the role of DNA methylation in normal development and how it may contribute to a rodent model of emotion dysfunction.

DNA Modifications in the Brain

DNA Modifications in the Brain
  • Author : Timothy W. Bredy
  • Publisher : Academic Press
  • Release : 05 January 2017
GET THIS BOOK DNA Modifications in the Brain

DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate

Epigenetic pathways in PTSD how traumatic experiences leave their signature on the genome

Epigenetic pathways in PTSD  how traumatic experiences leave their signature on the genome
  • Author : Tania L Roth,David M Diamond,Karestan C Koenen
  • Publisher : Frontiers Media SA
  • Release : 14 April 2015
GET THIS BOOK Epigenetic pathways in PTSD how traumatic experiences leave their signature on the genome

This research topic focuses on epigenetic components of PTSD. Epigenetic mechanisms are a class of molecular mechanisms by which environmental influences, including stress, can interact with the genome to have long-term consequences for brain plasticity and behavior. Articles herein include empirical reports and reviews that link stress and trauma with epigenetic alterations in humans and animal models of early- or later-life stress. Themes present throughout the collection include: DNA methylation is a useful biomarker of stress and treatment outcome in

The Impact of Aversive Caregiving on DNA Methylation in Blood and the Prefrontal Cortex

The Impact of Aversive Caregiving on DNA Methylation in Blood and the Prefrontal Cortex
  • Author : Hannah Duffy
  • Publisher : Unknown
  • Release : 17 September 2021
GET THIS BOOK The Impact of Aversive Caregiving on DNA Methylation in Blood and the Prefrontal Cortex

Aversive caregiving causes epigenetic alterations that may lead to neurological and behavioral problems later in life. These issues presumably originate in the brain, and, as such, epigenetic changes within the brain would appear to be the most relevant to better understand the origin of and possible alleviation of these issues. However, it is difficult to study epigenetics in the brain in living humans, so many researchers rely on epigenetic alterations in peripheral tissues to be an indication of aberrant epigenetic

The Genetics and Epigenetics of Sex Differences in the Brain

The Genetics and Epigenetics of Sex Differences in the Brain
  • Author : Negar Montakhab Ghahramani
  • Publisher : Unknown
  • Release : 17 September 2021
GET THIS BOOK The Genetics and Epigenetics of Sex Differences in the Brain

The major drivers underlying sexually dimorphic brain development are gonadal hormones, namely testosterone (T). During the perinatal sensitive period, a time when the embryonic brain is maximally sensitive to changes in the levels of gonadal hormones, exposure to T has permanent organizing effects on the brain, the molecular basis of which is not known. One potential mechanism for the long term permanence may be DNA methylation. To examine the contribution of epigenetic mechanisms to both the establishment and maintenance of

Stress Genetics Epigenetics and Genomics

Stress  Genetics  Epigenetics and Genomics
  • Author : George Fink
  • Publisher : Academic Press
  • Release : 24 October 2020
GET THIS BOOK Stress Genetics Epigenetics and Genomics

This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases. The Handbook of Stress