Epigenetic Gene Expression And Regulation

Epigenetic Gene Expression And Regulation Book PDF
✏Book Title : Epigenetic Gene Expression and Regulation
✏Author : Suming Huang
✏Publisher : Academic Press
✏Release Date : 2015-10-19
✏Pages : 482
✏ISBN : 9780128004715
✏Available Language : English, Spanish, And French

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✏Epigenetic Gene Expression and Regulation Book Summary : Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science

📒Chromatin And Gene Regulation ✍ Bryan M. Turner

Chromatin And Gene Regulation Book PDF
✏Book Title : Chromatin and Gene Regulation
✏Author : Bryan M. Turner
✏Publisher : John Wiley & Sons
✏Release Date : 2008-04-15
✏Pages : 288
✏ISBN : 9780470751671
✏Available Language : English, Spanish, And French

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✏Chromatin and Gene Regulation Book Summary : Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to the rapid changes in gene transcription by which cells respond to changes in their environment and also to the maintenance of gene expression patterns from one cell generation to the next. This book will be an invaluable guide to undergraduate and postgraduate students in the biological sciences and all those with an interest in the medical implications of aberrant gene expression.

Exam Prep For Epigenetic Gene Expression And Regulation Book PDF
✏Book Title : Exam Prep for Epigenetic Gene Expression and Regulation
✏Author :
✏Publisher :
✏Release Date :
✏Pages :
✏ISBN :
✏Available Language : English, Spanish, And French

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✏Exam Prep for Epigenetic Gene Expression and Regulation Book Summary :

Deciphering The Gene Expression Control In Epigenetic Post Transcriptional And Translational Regulation Book PDF
✏Book Title : Deciphering the Gene Expression Control in Epigenetic Post transcriptional and Translational Regulation
✏Author : Jianan Lin
✏Publisher :
✏Release Date : 2019
✏Pages :
✏ISBN : OCLC:1196359731
✏Available Language : English, Spanish, And French

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✏Deciphering the Gene Expression Control in Epigenetic Post transcriptional and Translational Regulation Book Summary : Regulation of gene expression, through which cells increase or decrease the gene products, is an essential part of development, which not only determines the cellular differentiation but also responds to the environmental changes. A wide range of gene regulation mechanisms are involved in two major processes, from Deoxyribonucleic acid (DNA) to Ribonucleic acid (RNA), and from RNA to protein, also known as transcription and translation, respectively. Though the regulation of gene expression is not fully understood, this complex process has been characterized to several major steps, which includes epigenetic regulation, transcriptional regulation, post-transcriptional regulation and translational regulation. The present study covers three main projects related to three of the aforementioned steps of gene regulation. First, we study the DNA methylation dynamics in the bovine early embryos. To understand the epigenetic reprogramming and regulation in the embryonic development, we characterize the methylation process at the single-base level in early embryos. Second, we develop a novel method, called Protein-RNA Association Strength (PRAS), to predict the functional targets of RNA-Binding Proteins (RBPs) that play important roles in the regulation of gene expression in the post-transcriptional process. The development of various Cross-linking and immunoprecipitation with high-throughput sequencing (CLIP-seq) data makes it possible to investigate the transcriptomic binding sites of RBPs. We aim to fill the gap between the peak-calling methods and the interpretation of RBPs' biological functions based on CLIP-seq data. Third, we study the regulation of c-MYC on the mRNA translation. The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and cell behavior. We study how MYC affects the global translation of mRNAs and the translation start-site usage in the human lymphoma cell line. In sum, we perform data analysis and methodology development in these three specific projects related to the regulation of gene expression, which will help us better understand the central dogma of biology.

Recent Advances Of Epigenetics In Crop Biotechnology Book PDF
✏Book Title : Recent Advances of Epigenetics in Crop Biotechnology
✏Author : Clelia De-la-Peña
✏Publisher : Frontiers Media SA
✏Release Date : 2016-05-31
✏Pages :
✏ISBN : 9782889198542
✏Available Language : English, Spanish, And French

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✏Recent Advances of Epigenetics in Crop Biotechnology Book Summary : Epigenetics is a new field that explains gene expression at the chromatin structure and organization level. Three principal epigenetic mechanisms are known and hundreds of combinations among them can develop different phenotypic characteristics. DNA methylation, histone modifications and small RNAs have been identified, and their functions are being studied in order to understand the mechanisms of interaction and regulation among the different biological processes in plants. Although, fundamental epigenetic mechanisms in crop plants are beginning to be elucidated, the comprehension of the different epigenetic mechanisms, by which plant gene regulation and phenotype are modified, is a major topic to develop in the near future in order to increase crop productivity. Thus, the importance of epigenetics in improving crop productivity is undoubtedly growing. Current research on epigenetics suggest that DNA methylation, histone modifications and small RNAs are involved in almost every aspect of plant life including agronomically important traits such as flowering time, fruit development, responses to environmental factors, defense response and plant growth. The aim of this Research Topic is to explore the recent advances concerning the role of epigenetics in crop biotechnology, as well as to enhance and promote interactions among high quality researchers from different disciplines such as genetics, cell biology, pathology, microbiology, and evolutionary biology in order to join forces and decipher the epigenetic mechanisms in crop productivity.

Non Coding Rnas And Epigenetic Regulation Of Gene Expression Book PDF
✏Book Title : Non coding RNAs and Epigenetic Regulation of Gene Expression
✏Author : Kevin V. Morris
✏Publisher : Horizon Scientific Press
✏Release Date : 2012
✏Pages : 216
✏ISBN : 9781904455943
✏Available Language : English, Spanish, And French

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✏Non coding RNAs and Epigenetic Regulation of Gene Expression Book Summary : Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some form of RNA-based transcriptional and epigenetic regulatory control. This form of regulation may be controlled by selective pressures and influence the adaptability of the cell. The concept that RNA can control epigenetic states impacts our understanding of the basic fabric of the cell and may have therapeutic potential. Many studies have been carried out on the modulation of gene transcription by non-coding RNAs. This book, written by a group of distinguished scientists, represents an important overview and summary of the field to date. The 13 chapters are organized into three sections: a) Non-coding RNAs: Form, Function and Diversity; b) Non-coding RNAs: Gene Regulation and Epigenetics; and c) Non-coding RNAs: Disease and Therapeutics. This up-to-date volume is an essential book for those working in the area and represents a major information resource on current research in the fast-moving fields of epigenetics, the regulation of gene expression, and RNA research.

Epigenetics In Biology And Medicine Book PDF
✏Book Title : Epigenetics in Biology and Medicine
✏Author : Manel Esteller
✏Publisher : CRC Press
✏Release Date : 2008-09-17
✏Pages : 312
✏ISBN : 1420007076
✏Available Language : English, Spanish, And French

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✏Epigenetics in Biology and Medicine Book Summary : Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an all-inclusive overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Epigenetics, in its

Gene Regulation Epigenetics And Hormone Signaling Book PDF
✏Book Title : Gene Regulation Epigenetics and Hormone Signaling
✏Author : Subhrangsu S. Mandal
✏Publisher : John Wiley & Sons
✏Release Date : 2017-10-23
✏Pages : 668
✏ISBN : 9783527322817
✏Available Language : English, Spanish, And French

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✏Gene Regulation Epigenetics and Hormone Signaling Book Summary : The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major emphasis is placed on pathological conditions, aiming at the many physiologists and developmental biologists who are familiar with the importance and mechanisms of hormone regulation but have a limited background in epigenetics.

Gene Expression And Regulation In Mammalian Cells Book PDF
✏Book Title : Gene Expression and Regulation in Mammalian Cells
✏Author : Fumiaki Uchiumi
✏Publisher : BoD – Books on Demand
✏Release Date : 2018-02-21
✏Pages : 334
✏ISBN : 9789535138556
✏Available Language : English, Spanish, And French

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✏Gene Expression and Regulation in Mammalian Cells Book Summary : "Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

Epigenetic Gene Regulation In Mouse Embryonic Stem Cells And The Developing Central Nervous System Book PDF
✏Book Title : Epigenetic Gene Regulation in Mouse Embryonic Stem Cells and the Developing Central Nervous System
✏Author : Shaun David Fouse
✏Publisher :
✏Release Date : 2008
✏Pages : 316
✏ISBN : UCLA:L0099890899
✏Available Language : English, Spanish, And French

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✏Epigenetic Gene Regulation in Mouse Embryonic Stem Cells and the Developing Central Nervous System Book Summary :

📒Epigenetics ✍ C. David Allis

Epigenetics Book PDF
✏Book Title : Epigenetics
✏Author : C. David Allis
✏Publisher : CSHL Press
✏Release Date : 2007-01
✏Pages : 502
✏ISBN : 9780879697242
✏Available Language : English, Spanish, And French

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✏Epigenetics Book Summary : The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

Epigenetic Regulation And Epigenomics Book PDF
✏Book Title : Epigenetic Regulation and Epigenomics
✏Author : Robert A. Meyers
✏Publisher : John Wiley & Sons
✏Release Date : 2012-10-02
✏Pages : 1254
✏ISBN : 9783527668625
✏Available Language : English, Spanish, And French

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✏Epigenetic Regulation and Epigenomics Book Summary : Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA and the chromatin proteins that associate with it. Methylation, for example, can silence a nearby gene and seems to be involved in some cancers. Epigenetics is beginning to form and take shape as a new scientific discipline, which will have a major impact on Medicine and essentially all fields of biology. Increasingly, researchers are unearthing links between epigenetics and a number of diseases. Although in recent years cancer has been the main focus of epigenetics, recent data suggests that epigenetic plays a critical role in psychology and psychopathology. It is being realized that normal behaviors such as maternal care and pathologies such as Schizophrenia and Alzheimer's might have an epigenetic basis. It is also becoming clear that nutrition and life experiences have epigenetic consequences. Discover more online content in the Encyclopedia of Molecular Cell Biology and Molecular Medicine.

Epigenetic Gene Regulation In The Mammalian Central Nervous System And Its Implications In Rett Syndrome Book PDF
✏Book Title : Epigenetic Gene Regulation in the Mammalian Central Nervous System and Its Implications in Rett Syndrome
✏Author : Keri Martinowich
✏Publisher :
✏Release Date : 2006
✏Pages : 288
✏ISBN : UCLA:L0096927363
✏Available Language : English, Spanish, And French

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✏Epigenetic Gene Regulation in the Mammalian Central Nervous System and Its Implications in Rett Syndrome Book Summary :

📒Epigenetics ✍ Bruce Stillman

Epigenetics Book PDF
✏Book Title : Epigenetics
✏Author : Bruce Stillman
✏Publisher : CSHL Press
✏Release Date : 2004
✏Pages : 532
✏ISBN : 9780879697310
✏Available Language : English, Spanish, And French

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✏Epigenetics Book Summary : The importance of epigenetic regulation of gene expression, particularly in higher organisms, is now clear and the 2004 Cold Spring Harbor Annual Symposium provided many new examples as well as insights into the underlying mechanisms. The resulting volume—with over 60 papers from experts across the field—covers various aspects of nuclear organization and dynamics; genomic imprinting, chromosomal inactivation, and other examples of gene silencing; the histone and DNA modifications associated with these conditions; and the roles of RNA and protein regulators in establishing and maintaining these states.

Genetic And Epigenetic Regulation Of Gene Expression In Pancreatic Islets Book PDF
✏Book Title : Genetic and Epigenetic Regulation of Gene Expression in Pancreatic Islets
✏Author : Nikolina Nakic
✏Publisher :
✏Release Date : 2016
✏Pages :
✏ISBN : OCLC:1104034543
✏Available Language : English, Spanish, And French

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✏Genetic and Epigenetic Regulation of Gene Expression in Pancreatic Islets Book Summary :

Study Of Genetic And Epigenetic Determinants Of Gene Expression Regulation For Both Sl Genes In Response To Estrogen In Common Carp Cyprinus Carpio  Book PDF
✏Book Title : Study of Genetic and Epigenetic Determinants of Gene Expression Regulation for Both SL Genes in Response to Estrogen in Common Carp Cyprinus Carpio
✏Author : Guillermo Eduardo Valenzuela Nieto
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1107350353
✏Available Language : English, Spanish, And French

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✏Study of Genetic and Epigenetic Determinants of Gene Expression Regulation for Both SL Genes in Response to Estrogen in Common Carp Cyprinus Carpio Book Summary :

Transcriptomics And Gene Regulation Book PDF
✏Book Title : Transcriptomics and Gene Regulation
✏Author : Jiaqian Wu
✏Publisher : Springer
✏Release Date : 2015-11-17
✏Pages : 185
✏ISBN : 9789401774505
✏Available Language : English, Spanish, And French

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✏Transcriptomics and Gene Regulation Book Summary : This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencing analyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein and gene expression data integration in complex human diseases etc. The book is particularly useful for researchers and students in the field of molecular biology, clinical biology and bioinformatics, as well as physicians etc. Dr. Jiaqian Wu is assistant professor in the Vivian L. Smith Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Centre, Houston, TX, USA.​

📒Handbook Of Epigenetics ✍ Trygve Tollefsbol

Handbook Of Epigenetics Book PDF
✏Book Title : Handbook of Epigenetics
✏Author : Trygve Tollefsbol
✏Publisher : Academic Press
✏Release Date : 2010-11-21
✏Pages : 638
✏ISBN : 012375710X
✏Available Language : English, Spanish, And French

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✏Handbook of Epigenetics Book Summary : Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and imprinting diseases are on the horizon. This comprehensive collection of reviews written by leaders in the field of epigenetics provides a broad view of this important and evolving topic. From molecular mechanisms and epigenetic technology to discoveries in human disease and clinical epigenetics, the nature and applications of the science will be presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders. Contributions by leading international investigators involved in molecular research and clinical and therapeutic applications Integrates methods and biological topics with basic and clinical discoveries Includes coverage of new topics in epigenetics such as prions, regulation of long-term memory by epigenetics, metabolic aspects of epigenetics, and epigenetics of neuronal disorders

Chromatin Structure And Gene Expression Book PDF
✏Book Title : Chromatin Structure and Gene Expression
✏Author : Sarah C. Elgin
✏Publisher : Oxford University Press, USA
✏Release Date : 1995
✏Pages : 224
✏ISBN : UOM:39015034891948
✏Available Language : English, Spanish, And French

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✏Chromatin Structure and Gene Expression Book Summary : Using the tools of molecular biology, genetics and biochemistry, this study charts the progress that has been made in defining chromatin structure and identifying potential mechanisms for regulation.

Epigenetic Regulation Of Mouse Delta Opioid Receptor Gene Book PDF
✏Book Title : Epigenetic Regulation of Mouse Delta opioid Receptor Gene
✏Author : Guilin Wang (Ph.D.)
✏Publisher :
✏Release Date : 2005
✏Pages : 316
✏ISBN : MINN:31951P01066916Q
✏Available Language : English, Spanish, And French

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✏Epigenetic Regulation of Mouse Delta opioid Receptor Gene Book Summary :

📒Patho Epigenetics Of Disease ✍ Janos Minarovits

Patho Epigenetics Of Disease Book PDF
✏Book Title : Patho Epigenetics of Disease
✏Author : Janos Minarovits
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-06-14
✏Pages : 466
✏ISBN : 9781461433453
✏Available Language : English, Spanish, And French

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✏Patho Epigenetics of Disease Book Summary : In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA sequences. Because DNA methyltransferase I (DNMT1) associates with replication foci during S phase and prefers hemimethylated DNA as a substrate, DNMT1 ensures the clonal propagation of cytosine methylation patterns (maintenance methylation). Thus, DNA methylation may provide a memory function by helping progeny cells to “remember” their proper cellular identity. An alternative system of epigenetic memory, the Polycomb and Trithorax groups of protein complexes, that may operate both independently from and in concert with DNA methylation, ensures the heritable regulation of gene expression via modification of histone tails. The complex interplay of epigenetic regulatory mechanisms permits both the dynamic modulation of gene expression and the faithful transmission of gene expression patterns to each progeny cell upon division. These carefully orchestrated processes can go wrong, however, resulting in epigenetic reprogramming of the cells that may manifest in pathological changes, as it was first realized during the studies of epigenetic alterations in malignant tumors. By now it became a well established fact that not only genetic changes, but also the disruption of epigenetic regulation can result in carcinogenesis and tumor progression. Scientists working in other fields soon followed the pioneering work of cancer researchers, and revealed that epigenetic dysregulation forms the basis of a wide spectrum of human diseases.

Epigenetic Approaches In Drug Discovery Development And Treatment Book PDF
✏Book Title : Epigenetic Approaches in Drug Discovery Development and Treatment
✏Author : Shibashish Giri
✏Publisher : Frontiers Media SA
✏Release Date : 2020-08-07
✏Pages :
✏ISBN : 9782889639328
✏Available Language : English, Spanish, And French

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✏Epigenetic Approaches in Drug Discovery Development and Treatment Book Summary : Establishment of a normal phenotype involves dynamic epigenetic regulation of gene expression that when affected contributes to human diseases. On a molecular level, epigenetic regulation is marked by specific covalent modifications (acetylation, methylation, phosphorylation, sumoylation, PARylation and ubiquitylation) of DNA and its associated histones. Studies also suggest the influence of such epigenetic modifications on non-coding RNA expression implicated in normal and diseased phenotypes. Epigenetic control of genetic expression is a reversible process essential for normal development and function of an organism. Alteration of epigenetic regulation leads to various disease forms such as cancer, diabetes, inflammation and neuropsychiatric disorders. Assessing these alterations provides a deeper insight into the changes induced in the genome, which is often informative for identifying disease subtypes or developing suitable treatments. Therefore, epigenetics proves to be a key area of clinical investigation in diagnosis, prognosis, and treatment of complex diseases. Genetic mutations, environmental stress, pathogens and drugs of abuse are some of the predominant factors that induce and impact changes on chromatin, which directly dictate a diseased phenotype. It is essential to consider the interaction between genetic and epigenetic factors to understand the molecular mechanisms of complex human diseases for safer and efficient drug development. Furthermore, genetic variation in absorption, distribution, metabolism, and excretion (ADME) genes is insufficient to account for interindividual variability of drug response. Therefore, current efforts aim to identify epigenetic components of ADME gene regulation, which include phase-I and phase-II enzymes, uptake transporters, efflux transporters and nuclear receptors involved in regulation of ADME genes. Monitoring circulatory epigenetic biomarkers in liquid biopsies (blood, saliva, urine, cerebrospinal fluid) of disease-associated and drug-associated epigenetic alterations may prove useful for decision support for routine clinical treatment and drug discovery. Hence, recent drug discovery efforts on targeting the epigenome, has emerged an area of interest with several new drugs being developed, tested and some already approved by the US Food and Drug Administration (FDA). These new insights into the complexities of epigenetic regulation are key contributors to our basic understanding of this process in human health and disease, which will provide scope for innovative drug therapies. It is of urgency to aid the present understanding of epigenomics driven diseased outcomes, with the expectation that further studies will identify early markers of disease and targets for therapeutics.

📒Epigenetics ✍ Lyle Armstrong

Epigenetics Book PDF
✏Book Title : Epigenetics
✏Author : Lyle Armstrong
✏Publisher : Garland Science
✏Release Date : 2013-11-20
✏Pages : 300
✏ISBN : 9781317683155
✏Available Language : English, Spanish, And French

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✏Epigenetics Book Summary : The concept of epigenetics has been known about since the 1940s, but it is only in the last 10 years that research has shown just how wide ranging its effects are. It is now a very widely-used term, but there is still a lot of confusion surrounding what it actually is and does. Epigenetics is a new textbook that brings together the structure and machinery of epigenetic modification, how epigenetic modification controls cellular functions, and the evidence for the relationship between epigenetics and disease. It is a valuable source of information about all aspects of the subject for undergraduate students, graduate students, and professionals.

Specific Gene Expression And Epigenetics Book PDF
✏Book Title : Specific Gene Expression and Epigenetics
✏Author : Kasirajan Ayyanathan
✏Publisher : CRC Press
✏Release Date : 2014-03-18
✏Pages : 328
✏ISBN : 9781482253856
✏Available Language : English, Spanish, And French

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✏Specific Gene Expression and Epigenetics Book Summary : This title includes a number of Open Access chapters. This new volume on gene expression and epigenetics discusses environmental effects related to specific gene expression. The book also shows methods for bioinformatic analysis of the epigenome. The book is broken into two sections: the first looks at eukaryotic DNA methylation and the second addresses how to integrate genomic medicine into clinical practice. The book includes chapters on these topics: • Gene expression in colon cancer tissue • Epigenetics in human acute kidney injury • Embryologically relevant candidate genes in MRKH patients • DNA methylation in common skeletal disorders • Causal relationships in genomics • Predicting severe asthma exacerbations in children • Epigenetic understanding of gene-environment interactions in psychiatric disorders

Epigenetic Mechanisms Of Gene Regulation Book PDF
✏Book Title : Epigenetic Mechanisms of Gene Regulation
✏Author : Vincenzo E. A. Russo
✏Publisher :
✏Release Date : 1996
✏Pages : 692
✏ISBN : UOM:39015047449171
✏Available Language : English, Spanish, And French

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✏Epigenetic Mechanisms of Gene Regulation Book Summary : Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

Epigenetic Shaping Of Sociosexual Interactions From Plants To Humans Book PDF
✏Book Title : Epigenetic Shaping of Sociosexual Interactions From Plants to Humans
✏Author :
✏Publisher : Academic Press
✏Release Date : 2014-09-03
✏Pages : 326
✏ISBN : 0128002220
✏Available Language : English, Spanish, And French

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✏Epigenetic Shaping of Sociosexual Interactions From Plants to Humans Book Summary : Epigenetic Shaping of Sociosexual Interactions: From Plants to Humans is the first attempt to interpret the higher social functions of organisms. This volume covers an extraordinarily wide range of biological research and provides a novel framework for understanding human-specific brain functions. Covers an extraordinarily wide range of biological research Provides a novel framework for understanding human-specific brain functions.

📒Medical Physiology E Book ✍ Walter F. Boron

Medical Physiology E Book Book PDF
✏Book Title : Medical Physiology E Book
✏Author : Walter F. Boron
✏Publisher : Elsevier Health Sciences
✏Release Date : 2016-03-29
✏Pages : 1312
✏ISBN : 9781455733286
✏Available Language : English, Spanish, And French

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✏Medical Physiology E Book Book Summary : For a comprehensive understanding of human physiology — from molecules to systems —turn to the latest edition of Medical Physiology. This updated textbook is known for its unparalleled depth of information, equipping students with a solid foundation for a future in medicine and healthcare, and providing clinical and research professionals with a reliable go-to reference. Complex concepts are presented in a clear, concise, and logically organized format to further facilitate understanding and retention. Clear, didactic illustrations visually present processes in a clear, concise manner that is easy to understand. Intuitive organization and consistent writing style facilitates navigation and comprehension. Takes a strong molecular and cellular approach that relates these concepts to human physiology and disease. An increased number of clinical correlations provides a better understanding of the practical applications of physiology in medicine. Highlights new breakthroughs in molecular and cellular processes, such as the role of epigenetics, necroptosis, and ion channels in physiologic processes, to give insights into human development, growth, and disease. Several new authors offer fresh perspectives in many key sections of the text, and meticulous editing makes this multi-authored resource read with one unified voice. Includes electronic access to 10 animations and copious companion notes prepared by the Editors.

Dna Modifications In The Brain Book PDF
✏Book Title : DNA Modifications in the Brain
✏Author : Timothy W Bredy
✏Publisher : Academic Press
✏Release Date : 2016-12-23
✏Pages : 180
✏ISBN : 9780128017814
✏Available Language : English, Spanish, And French

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✏DNA Modifications in the Brain Book Summary : DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease. Provides a comprehensive overview of the many facets of DNA modifications Discusses the impact of this dynamic epigenetic mechanism across brain development and lifespan at behavioral, cognitive, molecular and genetic levels Contains contributions by influential leaders in the field Edited by a Neuroscientist to further promote synthesis between epigenetics, neuroscience, and clinical relevance

📒Epigenetics Of Aging ✍ Trygve O. Tollefsbol

Epigenetics Of Aging Book PDF
✏Book Title : Epigenetics of Aging
✏Author : Trygve O. Tollefsbol
✏Publisher : Springer Science & Business Media
✏Release Date : 2009-11-11
✏Pages : 469
✏ISBN : 1441906398
✏Available Language : English, Spanish, And French

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✏Epigenetics of Aging Book Summary : Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

📒Long Range Control Of Gene Expression ✍ Veronica Van Heyningen

Long Range Control Of Gene Expression Book PDF
✏Book Title : Long range Control of Gene Expression
✏Author : Veronica Van Heyningen
✏Publisher : Academic Press
✏Release Date : 2008
✏Pages : 399
✏ISBN : 0123738814
✏Available Language : English, Spanish, And French

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✏Long range Control of Gene Expression Book Summary : Covers the progress in understanding the mechanisms for genomic control of gene expression. This book includes information on aspergillus genomes. It discusses sex and its role in virulence of human fungal pathogens. It also covers the genomic analysis of neurospora.