Epigenetic Gene Expression and Regulation

Produk Detail:
  • Author : Suming Huang
  • Publisher : Academic Press
  • Pages : 482 pages
  • ISBN : 0128004711
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Epigenetic Gene Expression and Regulation

Download or Read online Epigenetic Gene Expression and Regulation full in PDF, ePub and kindle. this book written by Suming Huang and published by Academic Press which was released on 19 October 2015 with total page 482 pages. We cannot guarantee that Epigenetic Gene Expression and Regulation book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science

Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
  • Author : Suming Huang,Michael D Litt,C. Ann Blakey
  • Publisher : Academic Press
  • Release : 19 October 2015
GET THIS BOOK Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a

Epigenetic Mechanisms of Gene Regulation

Epigenetic Mechanisms of Gene Regulation
  • Author : Vincenzo E. A. Russo,Robert A. Martienssen,Arthur D. Riggs
  • Publisher : Unknown
  • Release : 25 September 1996
GET THIS BOOK Epigenetic Mechanisms of Gene Regulation

Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects

Epigenetic Regulation and Epigenomics

Epigenetic Regulation and Epigenomics
  • Author : Robert A. Meyers
  • Publisher : John Wiley & Sons
  • Release : 02 October 2012
GET THIS BOOK Epigenetic Regulation and Epigenomics

Epigenetics is a term in biology referring to heritable traits that do not involve changes in the underlying DNA sequence of the organism. Epigenetic traits exist on top of or in addition to the traditional molecular basis for inheritance. The "epigenome" is a parallel to the word "genome," and refers to the overall epigenetic state of a cell. Cancer and stem cell research have gradually focused attention on these genome modifications. The molecular basis of epigenetics involves modifications to DNA

A Systems Biology Approach to Epigenetic Gene Regulation

A Systems Biology Approach to Epigenetic Gene Regulation
  • Author : Stephen Patrick Wilson
  • Publisher : Unknown
  • Release : 25 September 2021
GET THIS BOOK A Systems Biology Approach to Epigenetic Gene Regulation

The ability to control when, and how much of the genetic code is being expressed is the underlying principle behind gene regulation. Control of gene production is able to influence a cell's phenotype by determining which structural components of the cell's observable traits (shape, growth, and behavior) are made. In multicellular organism's different cell types are able to arise from the same genetic code due to a difference in the patterns of genes being expressed. Essentially anywhere in the process

Non coding RNAs and Epigenetic Regulation of Gene Expression

Non coding RNAs and Epigenetic Regulation of Gene Expression
  • Author : Kevin V. Morris
  • Publisher : Horizon Scientific Press
  • Release : 25 September 2021
GET THIS BOOK Non coding RNAs and Epigenetic Regulation of Gene Expression

Non-coding RNAs potentially play an active role in modulating gene transcription and epigenetic states. Several genes in differentiated cells may be under some form of RNA-based transcriptional and epigenetic regulatory control. This form of regulation may be controlled by selective pressures and influence the adaptability of the cell. The concept that RNA can control epigenetic states impacts our understanding of the basic fabric of the cell and may have therapeutic potential. Many studies have been carried out on the modulation

Chromatin and Gene Regulation

Chromatin and Gene Regulation
  • Author : Bryan M. Turner
  • Publisher : John Wiley & Sons
  • Release : 15 April 2008
GET THIS BOOK Chromatin and Gene Regulation

Written in an informal and accessible style, Chromatin and Gene Regulation enables the reader to understand the science of this rapidly moving field. Chromatin is a fundamental component in the network of controls that regulates gene expression. Many human diseases have been linked to disruption of these control processes by genetic or environmental factors, and unravelling the mechanisms by which they operate is one of the most exciting and rapidly developing areas of modern biology. Chromatin is central both to

Epigenetics and Disease

Epigenetics and Disease
  • Author : Susan M. Gasser,En Li
  • Publisher : Springer Science & Business Media
  • Release : 17 October 2010
GET THIS BOOK Epigenetics and Disease

Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to degenerative diseases, cancer and neuronal disorders. Recent biomedical interest in this regulatory system stems from the fact that epigenetic, in contrast to genetic, alterations are in principle amenable to pharmacological intervention. A few epigenetically active drugs, for example histone deacetylase inhibitors (HDACi) and

Global Epigenetic Profiling in Malignant and Normal Urothelial Cell Lines

Global Epigenetic Profiling in Malignant and Normal Urothelial Cell Lines
  • Author : Ewa Dudziec
  • Publisher : Unknown
  • Release : 25 September 2021
GET THIS BOOK Global Epigenetic Profiling in Malignant and Normal Urothelial Cell Lines

Epigenetic regulation of gene expression IS commonly altered in human cancer. Numerous alterations of DNA methylation and microRNA expression have been described in bladder cancer and these reflect the biology and phenotype of the disease. This common disease arises by distinct pathways with low and high grade differentiation. Epigenetic gene regulation is stabilized within a chromatin state by maintainers such as histone modification or DNA methylation. I hypothesized that epigenetic gene regulation reflects an interaction between histone and DNA modifications,

Epigenetic Modifications and Viral Infections

Epigenetic Modifications and Viral Infections
  • Author : Silvia Carolina Galvan,Alejandro García Carrancá,Félix Recillas-Targa,Jiuzhou Song
  • Publisher : Frontiers Media SA
  • Release : 09 July 2015
GET THIS BOOK Epigenetic Modifications and Viral Infections

Epigenetics is defined as the study of modifications of the genome, heritable during cell division that does not involve changes in DNA sequences. Up to date, epigenetic modifications involve at least three general mechanisms regulating gene expression: histone modifications, DNA methylation, and non-coding RNAs (ncRNAs). For the past two decades, an explosion in our interest and understanding of epigenetic mechanisms has been seen. This mainly based on the influence that epigenetic alterations have on an amazing number of biological processes,

Nutrition in Epigenetics

Nutrition in Epigenetics
  • Author : Mihai D. Niculescu,Paul Haggarty
  • Publisher : John Wiley & Sons
  • Release : 25 March 2011
GET THIS BOOK Nutrition in Epigenetics

The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics reviews the latest research looking at the interaction between genes and nutrients and the role they play together in

Long Range Control of Gene Expression

Long Range Control of Gene Expression
  • Author : Veronica van Heyningen,Robert E Hill
  • Publisher : Academic Press
  • Release : 02 September 2011
GET THIS BOOK Long Range Control of Gene Expression

Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer

Epigenetics

Epigenetics
  • Author : Reinhard Heil,Stefanie B. Seitz,Harald König,Jürgen Robienski
  • Publisher : Springer
  • Release : 31 January 2017
GET THIS BOOK Epigenetics

Modern epigenetics unites scientists from life sciences, organic chemistry as well as computer and engineering sciences to find an answer to the question of how environmental influences can have a lasting effect on gene expression, maybe even into the next generations. This volume examines from an interdisciplinary perspective the ethical, legal and social aspects of epigenetics.

Epigenetics How Environment Shapes Our Genes

Epigenetics  How Environment Shapes Our Genes
  • Author : Richard C. Francis
  • Publisher : W. W. Norton & Company
  • Release : 13 June 2011
GET THIS BOOK Epigenetics How Environment Shapes Our Genes

Goodbye, genetic blueprint. . . . The first book for general readers on the game-changing field of epigenetics. The burgeoning new science of epigenetics offers a cornucopia of insights—some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer.

Patho Epigenetics of Disease

Patho Epigenetics of Disease
  • Author : Janos Minarovits,Hans Helmut Niller
  • Publisher : Springer Science & Business Media
  • Release : 14 June 2012
GET THIS BOOK Patho Epigenetics of Disease

In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA sequences. Because DNA methyltransferase I (DNMT1) associates with replication foci during S phase and prefers hemimethylated DNA as a substrate, DNMT1 ensures the clonal propagation of cytosine methylation patterns (maintenance