Epigenetic Biomarkers and Diagnostics

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  • Author : José Luis García-Giménez
  • Publisher : Academic Press
  • Pages : 696 pages
  • ISBN : 0128019212
  • Rating : /5 from reviews
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Download or Read online Epigenetic Biomarkers and Diagnostics full in PDF, ePub and kindle. this book written by José Luis García-Giménez and published by Academic Press which was released on 07 December 2015 with total page 696 pages. We cannot guarantee that Epigenetic Biomarkers and Diagnostics book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies

Epigenetic Biomarkers and Diagnostics

Epigenetic Biomarkers and Diagnostics
  • Author : José Luis García-Giménez
  • Publisher : Academic Press
  • Release : 07 December 2015
GET THIS BOOK Epigenetic Biomarkers and Diagnostics

Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e.

Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of Wif1 Functional Relevance

Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of Wif1 Functional Relevance
  • Author : Xuesong Yang,楊雪松
  • Publisher : Open Dissertation Press
  • Release : 27 January 2017
GET THIS BOOK Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of Wif1 Functional Relevance

This dissertation, "Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of WIF1 Functional Relevance" by Xuesong, Yang, 楊雪松, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above

Epigenetics in Precision Medicine

Epigenetics in Precision Medicine
  • Author : Jose Luis Garcia-Gimenez
  • Publisher : Academic Press
  • Release : 15 August 2021
GET THIS BOOK Epigenetics in Precision Medicine

In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic

Epigenetic Biomarkers in Colorectal Cancer

Epigenetic Biomarkers in Colorectal Cancer
  • Author : Marc Tänzer
  • Publisher : Sudwestdeutscher Verlag Fur Hochschulschriften AG
  • Release : 01 March 2012
GET THIS BOOK Epigenetic Biomarkers in Colorectal Cancer

Complete print of the doctoral thesis approved by the department Center of Life and Food Sciences Weihenstephan of the Technical University Munich for obtaining the academic degree doctor of natural sciences (doctor rerum naturalium). This work describes the functional analysis of three selected epigenetic regulated genes as biomarkers for diagnosis, prognosis and response prediction of colorectal cancer.

Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma
  • Author : Michael J. Murphy
  • Publisher : Springer Science & Business Media
  • Release : 02 December 2011
GET THIS BOOK Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a

Biomarker

Biomarker
  • Author : Tapan Khan
  • Publisher : IntechOpen
  • Release : 27 April 2012
GET THIS BOOK Biomarker

Clinicians, scientists, and health care professionals use biomarkers or biological markers as a measure of a person’s present health condition or response to interventions. An ideal -biomarker should have the following criteria: (I) ability to detect fundamental features of the disease, (II) ability to differentiate from other closely related diseases, (III) ability to detect early stages and stages of progression, (IV) the method should be highly reliable, easy to perform and inexpensive, and (V) sample sources should be easily

Drug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics
  • Author : Gerda Egger,Paola Arimondo
  • Publisher : Academic Press
  • Release : 19 November 2015
GET THIS BOOK Drug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found mutated in different cancers; therefore, they provide attractive therapeutic targets. There has been great interest in developing and testing epigenetic drugs, which inhibit DNA methyltransferases, histone modifying enzymes or chromatin

Epigenetic Mechanisms in Cancer

Epigenetic Mechanisms in Cancer
  • Author : Sabita Saldanha
  • Publisher : Academic Press
  • Release : 16 November 2017
GET THIS BOOK Epigenetic Mechanisms in Cancer

Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences in childhood, sex-specific and race-specific cancers, and in doing so broadly illuminates the scope of epigenetic biomarkers in clinical environments. Chapters detail the major epigenetic process in humans consisting of

Medical Epigenetics

Medical Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 August 2021
GET THIS BOOK Medical Epigenetics

Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate