Engineering Drug Delivery Systems

Engineering Drug Delivery Systems Book PDF
✏Book Title : Engineering Drug Delivery Systems
✏Author : Ali Seyfoddin
✏Publisher : Woodhead Publishing
✏Release Date : 2019-11-15
✏Pages : 250
✏ISBN : 9780081025499
✏Available Language : English, Spanish, And French

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✏Engineering Drug Delivery Systems Book Summary : Engineering Drug Delivery Systems is an essential resource on a variety of biomaterials engineering approaches for creating drug delivery systems that have market and therapeutic potential. The book comprehensively discusses recent advances in the fields of biomaterials and biomedical sciences in relation to drug delivery. Chapters provide a detailed introduction to various engineering approaches in designing drug delivery systems, delve into the engineering of body functions, cover the selection, design and evaluation of biomaterials, and discuss the engineering of colloids as drug carriers. The book's final chapters address the engineering of implantable drug delivery systems and advances in drug delivery technology. This book is an invaluable resource for drug delivery, materials scientists and bioengineers within the pharmaceutical industry. Examines the properties and synthesis of biomaterials for successful drug delivery Discusses the important connection between drug delivery and tissue engineering Includes techniques and approaches applicable to a wide range of users Reviews innovative technologies in drug delivery systems such as 3-D printed devices for drug delivery

Engineering Of Biomaterials For Drug Delivery Systems Book PDF
✏Book Title : Engineering of Biomaterials for Drug Delivery Systems
✏Author : Anilkumar Parambath
✏Publisher : Woodhead Publishing
✏Release Date : 2018-02-01
✏Pages : 404
✏ISBN : 9780081017517
✏Available Language : English, Spanish, And French

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✏Engineering of Biomaterials for Drug Delivery Systems Book Summary : Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field. Provides a self-contained work for the field of biomaterials for drug delivery Summarizes the current knowledge on PEGylation and strategies for bypassing it Presents research on an important, though under-represented issue in biomaterials Written by a world-class team of research scientists, engineers and clinicians

Advanced Biomaterials In Biomedical Engineering And Drug Delivery Systems Book PDF
✏Book Title : Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems
✏Author : Naoya Ogata
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 381
✏ISBN : 9784431658832
✏Available Language : English, Spanish, And French

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✏Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems Book Summary : First of all, I would like to share the great pleasure of the successful five-day symposium with every participant in the 5th Iketani Conference which was held in Kagoshima from April1S (Tuesday) to 22 (Saturday), 1995. Outstanding speakers enthusiastically presented their up-to-the-minute results. Relatively little time was allotted for each presentation to ensure asdnuch time· as possible for intensive discussions on the particular topics that had just been p~esented: I was delighted to see that the lectures were of high quality, and the discu,ssionswere lively, exciting, and productive in a congenial atmosphere. We also had 92 papers in the poster ·session, in which young (and relatively young) scientists made every effort to present the novel results of their research in advanced biomaterials and drug delivery systems (DDS). I believe some of the research is most promising and will become noteworthy in the twenty-first century. It was a privilege for me to deliver a lecture at the special session of the symposium. In my introductory remarks, I pointed out five key terms in multifaceted biomaterials research: materials design, concept or methodology, devices, properties demanded, and fundamentals. I am confident that innovative progress in device manufacturing for end-use, e.g., artificial organs, vascular grafts, and DDS, can be brought about only through properly designed advanced materials that exhibit the desired functionality at the interface with any living body.

Design Of Controlled Release Drug Delivery Systems Book PDF
✏Book Title : Design of Controlled Release Drug Delivery Systems
✏Author : Xiaoling Li
✏Publisher : McGraw Hill Professional
✏Release Date : 2005-11-24
✏Pages : 435
✏ISBN : 9780071588836
✏Available Language : English, Spanish, And French

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✏Design of Controlled Release Drug Delivery Systems Book Summary : The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Tissue Engineering And Novel Delivery Systems Book PDF
✏Book Title : Tissue Engineering And Novel Delivery Systems
✏Author : Michael J. Yaszemski
✏Publisher : CRC Press
✏Release Date : 2003-11-04
✏Pages : 620
✏ISBN : 0203913337
✏Available Language : English, Spanish, And French

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✏Tissue Engineering And Novel Delivery Systems Book Summary : Essential to anyone working in the field, this reference focuses on rencent advancements in tissue construction, repair and regeneration examining developments in gene and drug therapy, the evolution of tissue-engineered products, and new technologies for the design of functional tissues and organ systems.

Engineering Polymer Systems For Improved Drug Delivery Book PDF
✏Book Title : Engineering Polymer Systems for Improved Drug Delivery
✏Author : Rebecca A. Bader
✏Publisher : John Wiley & Sons
✏Release Date : 2014-01-17
✏Pages : 496
✏ISBN : 9781118747803
✏Available Language : English, Spanish, And French

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✏Engineering Polymer Systems for Improved Drug Delivery Book Summary : Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.

Drug Delivery Systems Book PDF
✏Book Title : Drug Delivery Systems
✏Author :
✏Publisher : Academic Press
✏Release Date : 2019-10-23
✏Pages : 792
✏ISBN : 9780128145081
✏Available Language : English, Spanish, And French

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✏Drug Delivery Systems Book Summary : Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and product development topics are also explored. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of drug delivery systems within the pharmaceutical sciences industry and research, as well as in chemical engineering. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists. This book provides a comprehensive examination that is suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnologies, and related industries. Provides up-to-date information on how to translate the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as oral, parenteral, transdermal and inhalational Contains extensive references and further reading for course and self-study

📒Drug Delivery ✍ W. Mark Saltzman

Drug Delivery Book PDF
✏Book Title : Drug Delivery
✏Author : W. Mark Saltzman
✏Publisher : Oxford University Press
✏Release Date : 2001-03-15
✏Pages : 384
✏ISBN : 9780199879755
✏Available Language : English, Spanish, And French

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✏Drug Delivery Book Summary : Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

Collagen Based Drug Delivery Systems For Tissue Engineering Book PDF
✏Book Title : Collagen Based Drug Delivery Systems for Tissue Engineering
✏Author : Mădălina Georgiana Albu
✏Publisher :
✏Release Date : 2011
✏Pages :
✏ISBN : OCLC:1154277677
✏Available Language : English, Spanish, And French

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✏Collagen Based Drug Delivery Systems for Tissue Engineering Book Summary : Collagen-Based Drug Delivery Systems for Tissue Engineering.

📒Drug Delivery Aspects ✍ Ranjita Shegokar

Drug Delivery Aspects Book PDF
✏Book Title : Drug Delivery Aspects
✏Author : Ranjita Shegokar
✏Publisher : Academic Press
✏Release Date : 2020-03-27
✏Pages : 266
✏ISBN : 9780128218501
✏Available Language : English, Spanish, And French

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✏Drug Delivery Aspects Book Summary : Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems. Encompasses engineering and large-scale manufacturing of nanocarriers Considers preclinical, regulatory and ethical guidelines on nanoparticles Contains in-depth discussions on delivery of biologics, vaccines and sterilisation Industrial view on solid dispersions, milling techniques

Engineering Improvements For Epicardial Drug Delivery Systems Book PDF
✏Book Title : Engineering Improvements for Epicardial Drug Delivery Systems
✏Author : Shahrin Islam
✏Publisher :
✏Release Date : 2019
✏Pages : 80
✏ISBN : OCLC:1138949827
✏Available Language : English, Spanish, And French

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✏Engineering Improvements for Epicardial Drug Delivery Systems Book Summary : Cardiovascular diseases continue have a large disease burden despite advancements in technology, therapeutic modalities, and prevention efforts. For various cardiovascular pathologies, epicardial drug delivery systems have shown promise. Our group has developed a replenishable epicardial drug delivery device called Therepi that allows for repeat administrations of therapeutics without necessitating multiple invasive surgeries. The purpose of this thesis is to improve upon the Therepi device and utilize the platform to study the effects of specific therapeutics on cardiac function in a preclinical small animal myocardial infarction (MI) model. I first show that the fibrous capsule that forms around the polycarbonate membrane interface of the first iteration Therepi device post-implantation can impede transport of therapeutics from the device to the heart. Then, I utilize a modified version of Therepi without the polycarbonate membrane to study the effects of repeat administrations of FSTL1, a promising protein with great therapeutic potential, on cardiac function post-MI. Results from this study indicate that removal of the polycarbonate membrane reduces the formation of a fibrous capsule and that repeat administrations of FSTL1 improve cardiac function after MI. Following this, I utilize a computational macroscale model of Therepi to study the effect of important design parameters such as loading conditions, biomaterial geometry and orientation relative to the cardiac fibers on drug delivery to the myocardium. The simulations highlight the significance of the cardiac fiber anisotropy as a crucial factor in governing drug distribution on the epicardial surface and limiting factor for penetration into the myocardium. The multiscale model can be useful for rapid iteration of different device concepts and determination which designs for epicardial drug delivery may be optimal and most promising for the ultimate therapeutic goal. In the future, the findings from this thesis will be further investigated to develop an improved version of Therepi that allows for better device-tissue adhesion, conformability, and transport. The effects of repeat administrations of FSTL1 from the Therepi device will be elucidated further to mechanistically understand how cardiac function is improved through this strategy.

Nanomaterials In Drug Delivery Imaging And Tissue Engineering Book PDF
✏Book Title : Nanomaterials in Drug Delivery Imaging and Tissue Engineering
✏Author : Ashutosh Tiwari
✏Publisher : John Wiley & Sons
✏Release Date : 2013-02-19
✏Pages : 576
✏ISBN : 9781118644744
✏Available Language : English, Spanish, And French

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✏Nanomaterials in Drug Delivery Imaging and Tissue Engineering Book Summary : This groundbreaking, multidisciplinary work is one of the first books to cover Nanotheragnostics, the new developmental edge of nanomedicine. Through a collection of authoritative chapters, the book reports on nanoscopic therapeutic systems that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities. An invaluable reference for researchers in materials science, bioengineering, pharmacy, biotechnology, and nanotechnology, this volume features four main parts on biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and nanoscaffolds technology.

📒Drug Delivery Systems ✍ Stroeve Pieter

Drug Delivery Systems Book PDF
✏Book Title : Drug Delivery Systems
✏Author : Stroeve Pieter
✏Publisher : World Scientific
✏Release Date : 2017-11-27
✏Pages : 392
✏ISBN : 9789813201064
✏Available Language : English, Spanish, And French

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✏Drug Delivery Systems Book Summary : With the alarming increase in cancer diagnoses and genetic illnesses, traditional drug agents and their delivery media need to be re-evaluated to address a quickly evolving field. With newer smart materials for the controlled release of macromolecules, peptides, genetic material, etc. further complications arise, such as material performance, synthesis, functionalization and targeting, biological identity, and biocompatibility. The book provides a comprehensive overview of the recent developments on "smart" targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer. This field of research has been in its infancy and continues to face growth, and with it, further challenges and difficulties along the way toward maturity, which are accurately introduced in this book. Contents: Drug Delivery Systems: Possibilities and Challenges (Ryan Spitler, Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, Jim Q Ho, and Nastaran Sakhaie)Nanoparticles in Circulation: Blood Stability (Saeid Zanganeh, Tahereh Jafari, Nasser Khakpash, Mohsen Erfanzadeh, and Jim Q Ho)How do Nanoparticles (NPs) Pass Barriers? (Saeid Zanganeh, Ryan Spitler, Najme Javdani, and Jim Q Ho)Gated Porous Materials for Biomedical Application (FĂ©lix SancenĂłn, Erick Yu, Elena Aznar, M Dolores Marcos, and RamĂłn MartĂ­nez-Måñez)Controlled Release from Iron Oxide Nanoparticles (Masoud Rahman)The Reverse of Controlled Release: Controlled Sequestration of Species and Biotoxins into Nanoparticles (NPs) (Jenifer GĂłmez-Pastora, Eugenio Bringas, MarĂ­a LĂĄzaro-DĂ­ez, JosĂ© Ramos-Vivas, and Inmaculada Ortiz)Membranes for Controlled Release (Vida Araban, Neda Aslankoohi, and Mohammad Raoufi)Controlled Released from Hydrogel (Hossein Riahinezhad, Vida Araban, and Mohammad Raoufi)Nano Delivery Systems (Sophie Laurent, Afsaneh Lahooti, Saeed Shanehsazzadeh, and Robert N Muller)Legal Framework for Protection of Pharmaceutical Trade Marks in Europe and USA (Mohammad Hossein Erfanmanesh, and Shirin Sharifzadeh)Future Perspective on the Smart Delivery of Biomolecules (Erick Yu, FĂ©lix SancenĂłn, Elena Aznar, RamĂłn MartĂ­nez-Måñez, MarĂ­a Dolores Marcos, Mohammad J Hajipour, Morteza Mahmoudi, and Pieter Stroeve) Readership: Nanotechnologists; biomedical engineers; chemical engineers; materials scientists; biotechnology researchers; chemists; biological scientists; cell physiologists; medical scientists; gene therapists. Keywords: Drug Delivery Systems;Nanoparticles;Biomaterials;TargetingReview: Key Features: Comprehensive overview on "smart" targeting and drug delivery systemsUnderstanding of the biological identity of nanoparticles for drug delivery applicationsDetailed information on the legal framework for protection of pharmaceutical trade mark in Europe and the United States

📒Drug Delivery Systems ✍ Kewal K. Jain

Drug Delivery Systems Book PDF
✏Book Title : Drug Delivery Systems
✏Author : Kewal K. Jain
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-03-07
✏Pages : 251
✏ISBN : 9781588298911
✏Available Language : English, Spanish, And French

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✏Drug Delivery Systems Book Summary : In this concise and systematic book, a team of experts select the most important, cutting-edge technologies used in drug delivery systems. They take into account significant drugs, new technologies such as nanoparticles, and therapeutic applications. The chapters present step-by-step laboratory protocols following the highly successful Methods in Molecular BiologyTM series format, offering readily reproducible results vital for pharmaceutical physicians and scientists.

Nanoparticulate Drug Delivery Systems Book PDF
✏Book Title : Nanoparticulate Drug Delivery Systems
✏Author : Yoon Yeo
✏Publisher : John Wiley & Sons
✏Release Date : 2013-02-25
✏Pages : 324
✏ISBN : 9781118570517
✏Available Language : English, Spanish, And French

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✏Nanoparticulate Drug Delivery Systems Book Summary : Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

Nanoparticulate Drug Delivery Systems Book PDF
✏Book Title : Nanoparticulate Drug Delivery Systems
✏Author : Deepak Thassu
✏Publisher : CRC Press
✏Release Date : 2007-03-30
✏Pages : 376
✏ISBN : 1420008447
✏Available Language : English, Spanish, And French

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✏Nanoparticulate Drug Delivery Systems Book Summary : With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e

Controlled Drug Delivery Systems Book PDF
✏Book Title : Controlled Drug Delivery Systems
✏Author : Filippo Rossi
✏Publisher : Springer
✏Release Date : 2016-01-19
✏Pages : 100
✏ISBN : 9783319022888
✏Available Language : English, Spanish, And French

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✏Controlled Drug Delivery Systems Book Summary : This book offers a state-of-the-art overview of controlled drug delivery systems, covering the most important innovative applications. The principles of controlled drug release and the mechanisms involved in controlled release are clearly explained. The various existing polymeric drug delivery systems are reviewed, and new frontiers in material design are examined in detail, covering a wide range of polymer modification techniques. The concluding chapter is a case study focusing on use of a drug-eluting stent. The book is designed to provide the reader with a complete understanding of the mechanisms and design of controlled drug delivery systems, and to this end includes numerous step-by-step tutorials. It illustrates how chemical engineers can advance medical care by designing polymeric delivery systems that achieve either temporal or spatial control of drug delivery and thus ensure more effective therapy that eliminates the potential for both under- and overdosing.

Control Of Biological And Drug Delivery Systems For Chemical Biomedical And Pharmaceutical Engineering Book PDF
✏Book Title : Control of Biological and Drug Delivery Systems for Chemical Biomedical and Pharmaceutical Engineering
✏Author : Laurent Simon
✏Publisher : John Wiley & Sons
✏Release Date : 2012-11-27
✏Pages : 384
✏ISBN : 9781118396483
✏Available Language : English, Spanish, And French

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✏Control of Biological and Drug Delivery Systems for Chemical Biomedical and Pharmaceutical Engineering Book Summary : Enables readers to apply process dynamics and control theory to solve bioprocess and drug delivery problems The control of biological and drug delivery systems is critical to the health of millions of people worldwide. As a result, researchers in systems biology and drug delivery rely on process dynamics and control theory to build our knowledge of cell behavior and to develop more effective therapeutics, controlled release devices, and drug administration protocols to manage disease. Written by a leading expert and educator in the field, this text helps readers develop a deep understanding of process dynamics and control theory in order to analyze and solve a broad range of problems in bioprocess and drug delivery systems. For example, readers will learn how stability criteria can be used to gain new insights into the regulation of biological pathways and lung mechanics. They'll also learn how the concept of a time constant is used to capture the dynamics of diffusive processes. Readers will also master such topics as external disturbances, transfer functions, and input/output models with the support of the author's clear explanations, as well as: Detailed examples from the biological sciences and novel drug delivery technologies 160 end-of-chapter problems with step-by-step solutions Demonstrations of how computational software such as MATLAB and Mathematica solve complex drug delivery problems Control of Biological and Drug-Delivery Systems for Chemical, Biomedical, and Pharmaceutical Engineering is written primarily for undergraduate chemical and biomedical engineering students; however, it is also recommended for students and researchers in pharmaceutical engineering, process control, and systems biology. All readers will gain a new perspective on process dynamics and control theory that will enable them to develop new and better technologies and therapeutics to treat human disease.

Nanosized Drug Delivery Systems Colloids And Gels For Site Specific Targeting Book PDF
✏Book Title : Nanosized Drug Delivery Systems Colloids and Gels for Site Specific Targeting
✏Author : Francesco Cellesi
✏Publisher : Frontiers Media SA
✏Release Date : 2020-09-17
✏Pages :
✏ISBN : 9782889660223
✏Available Language : English, Spanish, And French

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✏Nanosized Drug Delivery Systems Colloids and Gels for Site Specific Targeting Book Summary :

📒Drug Delivery ✍ Yitzhak Rosen

Drug Delivery Book PDF
✏Book Title : Drug Delivery
✏Author : Yitzhak Rosen
✏Publisher : CRC Press
✏Release Date : 2017-09-19
✏Pages : 602
✏ISBN : 9781351643856
✏Available Language : English, Spanish, And French

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✏Drug Delivery Book Summary : Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterials, NEMS and MEMS devices, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound. The book is rounded out by a chapter on the FDA regulatory and bioethical challenges involved in advancing drug delivery.

📒Drug Delivery ✍ Eric P. Holowka

Drug Delivery Book PDF
✏Book Title : Drug Delivery
✏Author : Eric P. Holowka
✏Publisher : Springer
✏Release Date : 2014-11-22
✏Pages : 355
✏ISBN : 9781493919987
✏Available Language : English, Spanish, And French

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✏Drug Delivery Book Summary : Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments. Drug Delivery: Materials Design and Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on “Engineering Concepts” reviews the relevant fundamental principles that guide rational design. The following section on “Materials Design” discusses how the design process applies engineering concepts for use in physiological systems. A third section on “Implementation” discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on “Clinical Applications” which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. · Provides a comprehensive description of drug delivery systems from a materials perspective · Includes a wide-ranging discussion of clinical applications of drug delivery systems · Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. · Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material type

Natural Polymer Drug Delivery Systems Book PDF
✏Book Title : Natural Polymer Drug Delivery Systems
✏Author : Saurabh Bhatia
✏Publisher : Springer
✏Release Date : 2016-09-23
✏Pages : 225
✏ISBN : 9783319411293
✏Available Language : English, Spanish, And French

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✏Natural Polymer Drug Delivery Systems Book Summary : This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.

📒Controlled Drug Delivery Systems ✍ Emmanuel C. Opara

Controlled Drug Delivery Systems Book PDF
✏Book Title : Controlled Drug Delivery Systems
✏Author : Emmanuel C. Opara
✏Publisher : CRC Press
✏Release Date : 2020-02-28
✏Pages : 351
✏ISBN : 9780429582752
✏Available Language : English, Spanish, And French

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✏Controlled Drug Delivery Systems Book Summary : This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies. Where appropriate delivery vehicles and relevant release of specific agents in any of these categories in clinical application will be discussed. All chapters will highlight the translational aspects of the various technologies discussed and will provide insights into the advantages of such delivery systems over current ones in clinical or research use. Each technology reviewed in this book will have significant potential to improve patients' lives by enhancing the therapeutic efficacy of drugs. This book: Discusses the various factors that mitigate effective oral insulin delivery and the current status of research efforts to overcome these barriers along with recent clinical projections Examines the advantages and disadvantages of each drug delivery system Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract. In view of these wide-ranging technological areas, and the up-to-date discussions of opportunities and challenges associated with these applications, the book should provide readers from technology, materials science, pharmacology and clinical disciplines with very valuable information.

Novel Drug Delivery Systems For Phytoconstituents Book PDF
✏Book Title : Novel Drug Delivery Systems for Phytoconstituents
✏Author : Madhu Gupta
✏Publisher : CRC Press
✏Release Date : 2019-07-23
✏Pages : 336
✏ISBN : 9781351057622
✏Available Language : English, Spanish, And French

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✏Novel Drug Delivery Systems for Phytoconstituents Book Summary : Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.

📒Drug Delivery Systems ✍ Peter Johnson

Drug Delivery Systems Book PDF
✏Book Title : Drug Delivery Systems
✏Author : Peter Johnson
✏Publisher : John Wiley & Sons
✏Release Date : 1987
✏Pages : 282
✏ISBN : 3527265589
✏Available Language : English, Spanish, And French

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✏Drug Delivery Systems Book Summary : New drug delivery systems have been the focus of attention for the past 20 years. With a range of international contributions, this book summarizes current knowledge of site-specific, implantable, oral and other noninvasive (i.e. transdermal, nasal and ocular) systems, providing a comprehensive overview of the latest approaches to controlled release technology from both academic and industrial viewpoints. The authors not only present clear and concise accounts of current thinking, but additionally offer the reader some appropriate glimpses into the future, where the combination of drug delivery technology and advancing techniques in molecular biology and genetic engineering holds particular promise.

Liposome Based Drug Delivery Systems Book PDF
✏Book Title : Liposome Based Drug Delivery Systems
✏Author : Wan-Liang Lu
✏Publisher : Springer
✏Release Date : 2019-02-13
✏Pages : 400
✏ISBN : 3662493187
✏Available Language : English, Spanish, And French

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✏Liposome Based Drug Delivery Systems Book Summary : This volume mainly describes the protocols for fabrication of liposomal drug delivery system, and consists of three parts, namely, the advances in liposome-based drug delivery system, the general protocols for fabrication of drug-loading liposomes, and the protocols for preparation of functionalized liposome-based drug delivery system. It unearths the formulation of drug-loading liposomes, describes the detailed operation of liposomal formulation, and demonstrates their potential applications. This handbook is targeted at scientists, research students, and young investigators in pharmaceutical enterprises.

📒Nanotechnology In Drug Delivery ✍ Melgardt M. de Villiers

Nanotechnology In Drug Delivery Book PDF
✏Book Title : Nanotechnology in Drug Delivery
✏Author : Melgardt M. de Villiers
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-10-29
✏Pages : 662
✏ISBN : 0387776680
✏Available Language : English, Spanish, And French

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✏Nanotechnology in Drug Delivery Book Summary : The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described.

📒Bioadhesive Drug Delivery Systems ✍ Vincent M. Lenaerts

Bioadhesive Drug Delivery Systems Book PDF
✏Book Title : Bioadhesive Drug Delivery Systems
✏Author : Vincent M. Lenaerts
✏Publisher : CRC Press
✏Release Date : 1989-11-30
✏Pages : 240
✏ISBN : 084935367X
✏Available Language : English, Spanish, And French

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✏Bioadhesive Drug Delivery Systems Book Summary : This comprehensively written text covers, in-depth, all aspects of bioadhesive systems. Bioadhesive systems are presently playing a major role in the field because of their ability to maintain a dosage form at a precise body-site for a prolonged period of time over which the active principle is progressively released. Included in this book are descriptions of the different mucosae in healthy and pathological situations, a theoretical approach of polymers-mucin interactions, and a comparative description of the methods used to evaluate bioadhesion. Up-to-date reviews of pharmaceutical applications are also given - subdivided according to the route of administration and type of system. It also contains a chapter devoted to the fundamentals of bioadhesion. This reference is an indispensable guide for researchers in the pharmaceutical field as well as academic researchers.

Fundamentals And Applications Of Controlled Release Drug Delivery Book PDF
✏Book Title : Fundamentals and Applications of Controlled Release Drug Delivery
✏Author : Juergen Siepmann
✏Publisher : Springer Science & Business Media
✏Release Date : 2011-12-15
✏Pages : 594
✏ISBN : 9781461408819
✏Available Language : English, Spanish, And French

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✏Fundamentals and Applications of Controlled Release Drug Delivery Book Summary : This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.

📒Nano And Microscale Drug Delivery Systems ✍ Alexandru Mihai Grumezescu

Nano And Microscale Drug Delivery Systems Book PDF
✏Book Title : Nano and Microscale Drug Delivery Systems
✏Author : Alexandru Mihai Grumezescu
✏Publisher : William Andrew
✏Release Date : 2017-03-27
✏Pages : 514
✏ISBN : 9780323527286
✏Available Language : English, Spanish, And French

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✏Nano and Microscale Drug Delivery Systems Book Summary : Nano- and Microscale Drug Delivery Systems: Design and Fabrication presents the developments that have taken place in recent years in the field of micro- and nanoscale drug delivery systems. Particular attention is assigned to the fabrication and design of drug delivery systems in order to i) reduce the side effects of therapeutic agents, ii) increase their pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. This book is designed to offer a cogent, concise overview of current scholarship in this important area of research through its focus on the characterization and fabrication of a variety of nanomaterials for drug delivery applications. It is an invaluable reference source for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems. Shows how micro- and nanomaterials can be engineered to create more effective drug delivery systems Summarizes current nanotechnology research in the field of drug delivery systems Explores the pros and cons of using particular nanomaterials as therapeutic agents Serves as a valuable reference for both biomaterials scientists and biomedical engineers who want to learn more about how nanomaterials are engineered and used in the design of drug delivery nanosystems