Drug Metabolism in Diseases

Produk Detail:
  • Author : Wen Xie
  • Publisher : Academic Press
  • Pages : 294 pages
  • ISBN : 0128029633
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Drug Metabolism in Diseases

Download or Read online Drug Metabolism in Diseases full in PDF, ePub and kindle. this book written by Wen Xie and published by Academic Press which was released on 12 September 2016 with total page 294 pages. We cannot guarantee that Drug Metabolism in Diseases book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology. Written and edited by leaders in drug metabolism from academia and industry Covers important topics, such as pharmacogenomics, drug metabolism in transplant patients, xenobiotic receptors, drug metabolism in geriatric and pediatric populations, and more Highlights topics of importance in drug discovery and development, and for safe and effective drug use in the clinic

Drug Metabolism in Diseases

Drug Metabolism in Diseases
  • Author : Wen Xie
  • Publisher : Academic Press
  • Release : 12 September 2016
GET THIS BOOK Drug Metabolism in Diseases

Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states. Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and

Cytochrome P450 2E1 Its Role in Disease and Drug Metabolism

Cytochrome P450 2E1  Its Role in Disease and Drug Metabolism
  • Author : APARAJITA DEY
  • Publisher : Springer
  • Release : 14 February 2013
GET THIS BOOK Cytochrome P450 2E1 Its Role in Disease and Drug Metabolism

The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic

Drug Interactions in Infectious Diseases

Drug Interactions in Infectious Diseases
  • Author : Stephen C. Piscitelli,Keith A. Rodvold,Manjunath P. Pai
  • Publisher : Springer Science & Business Media
  • Release : 08 September 2011
GET THIS BOOK Drug Interactions in Infectious Diseases

The revised and up-to-date third edition of Drug Interactions in Infectious Diseases delivers a text that will enhance your clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The third edition features five new chapters that cover material not addressed in previous editions. These new chapters describe interactions with a number of drug classes such as non-HIV antiviral, antimalarial, antiparasitic, antihelmintic, macrolide, azalide and ketolide agents. A novel chapter on probe

Nuclear Receptors in Drug Metabolism

Nuclear Receptors in Drug Metabolism
  • Author : Wen Xie
  • Publisher : John Wiley & Sons
  • Release : 03 November 2008
GET THIS BOOK Nuclear Receptors in Drug Metabolism

This book gives you an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with the interdisciplinary understanding of these receptors and how they can be regulated. Pharmaceutical researchers will find this extremely useful in developing drugs for cancer, heart disease, and diabetes treatment. This comprehensive resource collects scattered materials into one handy, informative volume.

Cytochromes P450 Drug Metabolism Bioactivation and Biodiversity 2 0

Cytochromes P450  Drug Metabolism  Bioactivation and Biodiversity 2 0
  • Author : Patrick M. Dansette,Daniéle Werck-Reichhart
  • Publisher : MDPI
  • Release : 31 August 2021
GET THIS BOOK Cytochromes P450 Drug Metabolism Bioactivation and Biodiversity 2 0

This book, "Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity", presents five papers on human cytochrome P450 (CYP) and P450 reductase, three reviews on the role of CYPs in humans and their use as biomarkers, six papers on CYPs in microorganisms, and one study on CYP in insects. The first paper reports the in silico modeling of human CYP3A4 access channels. The second uses structural methods to explain the mechanism-based inactivation of CYP3A4 by mibefradil, 6,7-dihydroxy-bergamottin, and azamulin. The

Xenosensor Regulation of Enzymes and Transporters in Drug Exposure and Disease

Xenosensor Regulation of Enzymes and Transporters in Drug Exposure and Disease
  • Author : Matthew David Merrell
  • Publisher : Unknown
  • Release : 24 September 2021
GET THIS BOOK Xenosensor Regulation of Enzymes and Transporters in Drug Exposure and Disease

A large and varied array of xenobiotics (foreign chemicals) enters into our bodies every day. In order to prevent toxicity resulting from xenobiotic accumulation, the body has developed a complex and integrated network of enzymes and transporters to promote and control the metabolism and excretion of drugs and other compounds. Drug metabolizing enzymes are classified as oxidative (Phase I) or conjugative (Phase II), and generally result in increased hydrophilicity of their substrates. Drug transporters actively route xenobiotics into (Phase 0) or

30 Day Journal Tracker

30 Day Journal   Tracker
  • Author : Health Formation
  • Publisher : Unknown
  • Release : 04 January 2020
GET THIS BOOK 30 Day Journal Tracker

After relentlessly studying the teachings of legendary healers, such as Dr Arnold Ehret and Dr Robert Morse, we set out on a journey of healing ourselves and reversing our very own conditions. Within our group, we were suffering from a range of diverse diseases and conditions, including Heart Disease, Kidney Disease, Diabetes, a variety of Autoimmune Diseases and Leaky Gut. During our healing journeys, we formed a journal that we would use on a daily basis, and this helped us

30 Day Journal Tracker

30 Day Journal   Tracker
  • Author : Health Formation
  • Publisher : Unknown
  • Release : 04 January 2020
GET THIS BOOK 30 Day Journal Tracker

After relentlessly studying the teachings of legendary healers, such as Dr Arnold Ehret and Dr Robert Morse, we set out on a journey of healing ourselves and reversing our very own conditions. Within our group, we were suffering from a range of diverse diseases and conditions, including Heart Disease, Kidney Disease, Diabetes, a variety of Autoimmune Diseases and Leaky Gut. During our healing journeys, we formed a journal that we would use on a daily basis, and this helped us

30 Day Journal Tracker

30 Day Journal   Tracker
  • Author : Health Formation
  • Publisher : Unknown
  • Release : 04 January 2020
GET THIS BOOK 30 Day Journal Tracker

After relentlessly studying the teachings of legendary healers, such as Dr Arnold Ehret and Dr Robert Morse, we set out on a journey of healing ourselves and reversing our very own conditions. Within our group, we were suffering from a range of diverse diseases and conditions, including Heart Disease, Kidney Disease, Diabetes, a variety of Autoimmune Diseases and Leaky Gut. During our healing journeys, we formed a journal that we would use on a daily basis, and this helped us

New Applications of NMR in Drug Discovery and Development

New Applications of NMR in Drug Discovery and Development
  • Author : Leoncio Garrido,Nicolau Beckmann
  • Publisher : Royal Society of Chemistry
  • Release : 18 July 2013
GET THIS BOOK New Applications of NMR in Drug Discovery and Development

This book presents a review of recent developments in NMR applications in pharmaceutical research. Consideration is given to consolidated and emerging techniques and methods in NMR, many of which are not widely applied but are likely to provide new opportunities for drug design. The first part of the book is dedicated to the description of NMR as a tool for the analysis of chemicals and interaction with targets. Particular emphasis is put on applications with unexploited potential for drug discovery

The Art of Drug Synthesis

The Art of Drug Synthesis
  • Author : Douglas S. Johnson,Jie Jack Li
  • Publisher : John Wiley & Sons
  • Release : 26 February 2013
GET THIS BOOK The Art of Drug Synthesis

The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent

Lysosomes

Lysosomes
  • Author : Frederick R. Maxfield,James M. Willard,Shuyan Lu
  • Publisher : John Wiley & Sons
  • Release : 31 May 2016
GET THIS BOOK Lysosomes

Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and

Drug Interactions in Infectious Diseases

Drug Interactions in Infectious Diseases
  • Author : Stephen C. Piscitelli,Keith Rodvold
  • Publisher : Springer Science & Business Media
  • Release : 28 October 2007
GET THIS BOOK Drug Interactions in Infectious Diseases

Over the past 25 years, the world’s population has witnessed an explosion in kno- edge about infectious diseases. The global population is coming to the realization that diseases long recognized to cause substantial suffering, such as malaria, tuberculosis, schistosomiasis, and hepatitis, can be diagnosed and treated, and that transmission can be prevented using tools that are available, and which may be becoming increasingly affordable. The global population is recognizing that few infections are local: the travel of humans, other animals,