Discovery And Development Of Antidiabetic Agents From Natural Products

Discovery And Development Of Antidiabetic Agents From Natural Products Book PDF
✏Book Title : Discovery and Development of Antidiabetic Agents from Natural Products
✏Author : Goutam Brahmachari
✏Publisher : Elsevier
✏Release Date : 2016-10-11
✏Pages : 332
✏ISBN : 9780128096925
✏Available Language : English, Spanish, And French

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✏Discovery and Development of Antidiabetic Agents from Natural Products Book Summary : Discovery and Development of Antidiabetic Agents from Natural Products brings together global research on the medicinal chemistry of active agents from natural sources for the prevention and treatment of diabetes and associated disorders. From the identification of promising leads, to the extraction and synthesis of bioactive molecules, this book explores a range of important topics to support chemists in the discovery and development of safer, more economical therapeutics that are desperately needed in response to this emerging global epidemic. Beginning with an overview of bioactive chemical compounds from plants with anti-diabetic properties, the book goes on to outline the identification and extraction of anti-diabetic agents and antioxidants from natural sources. It then explores anti-diabetic plants from specific regions before looking more closely at the background, isolation, and synthesis of key therapeutic compounds and their derivatives, including Mangiferin, Resveratrol, natural saponins, and alpha-glucosidase enzyme inhibitors. The book concludes with a consideration of current and potential future applications. Combining the expertise of specialists from around the world, this volume aims to support and encourage medicinal chemists investigating natural sources as starting points for the development of standardized, safe, and effective antidiabetic therapeutics. Contains chapters written by active researchers and leading global experts who are deeply engaged in the research field of natural product chemistry for drug discovery Provides comprehensive coverage of cutting-edge research advances in the design of medicinal natural products with potential as preventives and therapeutics for diabetes and related metabolic issues Presents a practical review of the identification, isolation, and extraction techniques that help support medicinal chemists in the lab

Discovery And Development Of Neuroprotective Agents From Natural Products Book PDF
✏Book Title : Discovery and Development of Neuroprotective Agents from Natural Products
✏Author : Goutam Brahmachari
✏Publisher : Elsevier
✏Release Date : 2017-05-18
✏Pages : 490
✏ISBN : 9780128097694
✏Available Language : English, Spanish, And French

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✏Discovery and Development of Neuroprotective Agents from Natural Products Book Summary : Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab

Drug Discovery From Nature Book PDF
✏Book Title : Drug Discovery from Nature
✏Author : S. Grabley
✏Publisher : Springer Science & Business Media
✏Release Date : 1998-11-26
✏Pages : 347
✏ISBN : 3540648445
✏Available Language : English, Spanish, And French

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✏Drug Discovery from Nature Book Summary : This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.

Thermal Biosensors Bioactivity Bioaffinity Book PDF
✏Book Title : Thermal Biosensors Bioactivity Bioaffinity
✏Author : P.K. Bhatia
✏Publisher : Springer Science & Business Media
✏Release Date : 1999
✏Pages : 238
✏ISBN : 9783540649670
✏Available Language : English, Spanish, And French

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✏Thermal Biosensors Bioactivity Bioaffinity Book Summary : The immobilized biocatalyst (IMB) is a key component of biotransformation systems that are used to transform substrates to desired products. The impro- ment of biocatalyst properties has a direct influence on the overall effectiveness of the process based on the biotransformation. The basic catalytic characte- stics of biocatalyst that are followed include kinetic properties, pH optima, stability, and inhibition. The investigation of catalytic properties of immobilized enzymes is still a time consuming procedure and is not always simple. In the 1980s, a major effort was made to standardize the rules by which IMB is char- terized. The Working Party of EFB on immobilized biocatalysts has formul- ed principles of individual methods, among them the requirement of kinetic characterization [1]. It was recommended to use a packed-bed reactor, equipped with temperature control and with infinite flow circulation. The system should be equipped with a post-column unit to measure the time-dependence of the product or substrate concentration [2, 3], the most commonly used analytical methods being spectrophotometry, chemiluminiscence, automatic titration, bioluminiscence, chromatography, polarimetry, and biosensors based on the oxygen electrode. There are two main drawbacks to the application of these methods: 1. The need to vary the analytical principles, depending on the chemical and physical-chemical properties of analytes; 2. In some cases, mainly in the study of hydrolytic enzymes, the natural s- strate must be replaced by an artificial one, that is chromolytic, chromogenic, chemiluminiscent, bioluminiscent, or fluorescent.

Studies In Natural Products Chemistry Book PDF
✏Book Title : Studies in Natural Products Chemistry
✏Author : Suresh R. Naik
✏Publisher : Elsevier Inc. Chapters
✏Release Date : 2013-03-15
✏Pages : 504
✏ISBN : 9780128084922
✏Available Language : English, Spanish, And French

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✏Studies in Natural Products Chemistry Book Summary : Bioactive natural products are an excellent source of novel therapeutics. The search for bioactive molecules from nature continues to play a major role in developing new generation natural products of therapeutic importance. The present critical review includes research work carried out by active researchers in natural products’ chemistry, pharmacology and therapeutics, and their implications in antidiabetic medications. This compiled scientific information will be a useful resource for future research especially in indentifying promising leads and direction for the development of novel drugs including useful adjuvants for the treatment of diabetic patient. The present therapeutic approaches in the treatment of diabetes are mainly focused to lower the elevated blood glucose by reducing its absorption in gastrointestinal tract, enhancing the sensitivity of insulin, controlling or modulating hepatic glucose output, and increased utilization of the glucose by the peripheral tissues. Involvement of oxidative stress and its impact on the cellular damage in diabetes mellitus has been established and could be a useful paradigm for the development of novel antihyperglycemics along with other therapeutic strategies. The present review also highlights the effects of various herbs, phytoconstituents, phytochemicals, microbial metabolites, and products of marine origins on hyperglycemic/diabetic conditions. Furthermore, efforts were made to discuss novel molecular targets such as insulin-signaling pathways, peroxisome proliferative activating receptor-γ, and G-protein-coupled receptors that are participating in enhancing/influencing insulin secretion, critical carbohydrate metabolism pathways, endoplasmic reticulum stress-related pathways, intracellular events associated intracellular inflammation, and chromatin-modification pathways involvement in antidiabetic activity and their significance.

📒Natural Products ✍ Lixin Zhang

Natural Products Book PDF
✏Book Title : Natural Products
✏Author : Lixin Zhang
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-11-17
✏Pages : 386
✏ISBN : 9781592599769
✏Available Language : English, Spanish, And French

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✏Natural Products Book Summary : A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.

Environmental Health Perspectives Book PDF
✏Book Title : Environmental Health Perspectives
✏Author :
✏Publisher :
✏Release Date : 1993
✏Pages :
✏ISBN : UCR:31210014705337
✏Available Language : English, Spanish, And French

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✏Environmental Health Perspectives Book Summary :

📒Drug Discovery Handbook ✍ Shayne C. Gad

Drug Discovery Handbook Book PDF
✏Book Title : Drug Discovery Handbook
✏Author : Shayne C. Gad
✏Publisher : Wiley-Interscience
✏Release Date : 2005-07-11
✏Pages : 1471
✏ISBN : UOM:39015061016625
✏Available Language : English, Spanish, And French

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✏Drug Discovery Handbook Book Summary : THE FIRST COMPREHENSIVE GUIDE TO THE METHODS AND TECHNIQUES OF DRUG DISCOVERY The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of the latest techniques and methods in drug discovery, including: Genomics, proteomics, high-throughput screening, and systems biology Summaries of how these techniques and methods are used to discover new central nervous system agents, antiviral agents, respiratory drugs, oncology drugs, and more Specific approaches to drug discovery, including problems that are encountered, solutions to these problems, and limitations of various methods and techniques The thorough coverage and practical, scientifically valid problem-solving approach of Drug Discovery Handbook will serve as an invaluable aid in the complex task of developing new drugs.

📒Index Of Conference Proceedings Received ✍ British Library. Document Supply Centre

Index Of Conference Proceedings Received Book PDF
✏Book Title : Index of Conference Proceedings Received
✏Author : British Library. Document Supply Centre
✏Publisher :
✏Release Date : 1986
✏Pages :
✏ISBN : UOM:39015047344935
✏Available Language : English, Spanish, And French

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✏Index of Conference Proceedings Received Book Summary :

📒Chemistry Of The Amazon ✍ International Symposium on Chemistry and the Amazon

Chemistry Of The Amazon Book PDF
✏Book Title : Chemistry of the Amazon
✏Author : International Symposium on Chemistry and the Amazon
✏Publisher : Amer Chemical Society
✏Release Date : 1995
✏Pages : 315
✏ISBN : UOM:39015034296874
✏Available Language : English, Spanish, And French

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✏Chemistry of the Amazon Book Summary : Agroforest strategies for alleviating soil chemical constraints to food and fiber production in the Brazilian Amazon.

Two Centuries Of American Medicine 1776 1976 Book PDF
✏Book Title : Two Centuries of American Medicine 1776 1976
✏Author : James Bordley
✏Publisher : W B Saunders Company
✏Release Date : 1976
✏Pages : 844
✏ISBN : UOM:39015003216796
✏Available Language : English, Spanish, And French

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✏Two Centuries of American Medicine 1776 1976 Book Summary : Chronicles advances in medical education and the prevention and treatment of disease in the two hundred years since America's independence

Pharmacology And Therapeutics For Dentistry E Book Book PDF
✏Book Title : Pharmacology and Therapeutics for Dentistry E Book
✏Author : John A. Yagiela
✏Publisher : Elsevier Health Sciences
✏Release Date : 2010-03-19
✏Pages : 960
✏ISBN : 9780323078245
✏Available Language : English, Spanish, And French

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✏Pharmacology and Therapeutics for Dentistry E Book Book Summary : Use your knowledge of pharmacology to enhance oral care! Pharmacology and Therapeutics for Dentistry, 6th Edition describes how to evaluate a patient’s health and optimize dental treatment by factoring in the drugs they take. It explores the basic fundamentals of pharmacology, special topics such as pain control, fear and anxiety, and oral complications of cancer therapy, and most importantly, the actions of specific drug groups on the human body. Whether you’re concerned about the drugs a patient is already taking or the drugs you prescribe for treatment, this book helps you reduce risk and provide effective dental care. An emphasis on the dental applications of pharmacology relates drugs to dental considerations in clinical practice. Dental aspects of many drug classes are expanded to include antibiotics, analgesics, and anesthetics. The Alternative Medicine in Dentistry chapter discusses chemicals used as alternative medicines and assesses their potential benefits and risks. The Nonopioid Analgesics chapter groups together non-opioid analgesics, nonsterioidal anti-inflammatory drugs, and antirheumatic and antigout drugs, making these easier to locate and study. Coverage of the endocrine system includes four separate chapters for the most comprehensive coverage. Drug Interactions in Clinical Dentistry appendix lists potential interactions between drugs a patient is taking for nondental conditions and drugs that may be used or prescribed during dental treatment, including effects and recommendations. Glossary of Abbreviations appendix includes the most common abbreviations used for drugs or conditions. New Pharmacogenetics and Pharmacogenomics chapter covers the effects of genetic traits of patients on their responses to drugs. A NEW introductory section offers tips for the study of dental pharmacology and relates pharmacology to dental considerations. An updated discussion of drug-drug interactions covers the harmful effects of mixing medications. Coverage of adverse effects and mechanisms of COX-2 inhibitors, antibiotic prophylaxis, and antiplaque agents explains the dental risks relating to common drug treatments.

📒Pharmacology ✍ Ruth R. Levine

Pharmacology Book PDF
✏Book Title : Pharmacology
✏Author : Ruth R. Levine
✏Publisher :
✏Release Date : 1978
✏Pages : 513
✏ISBN : UOM:39015009502371
✏Available Language : English, Spanish, And French

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✏Pharmacology Book Summary :

Search Book PDF
✏Book Title : Search
✏Author :
✏Publisher :
✏Release Date : 1974
✏Pages :
✏ISBN : OSU:32435021939038
✏Available Language : English, Spanish, And French

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✏Search Book Summary :

Chemistry Towards Disease And Poverty Eradication Book PDF
✏Book Title : Chemistry Towards Disease and Poverty Eradication
✏Author :
✏Publisher :
✏Release Date : 2005
✏Pages : 365
✏ISBN : STANFORD:36105122918126
✏Available Language : English, Spanish, And French

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✏Chemistry Towards Disease and Poverty Eradication Book Summary :

The Journal Of Environment Development Book PDF
✏Book Title : The Journal of Environment Development
✏Author :
✏Publisher :
✏Release Date : 2001
✏Pages :
✏ISBN : NYPL:33433031992062
✏Available Language : English, Spanish, And French

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✏The Journal of Environment Development Book Summary :

📒Ethnobotany And The Search For New Drugs ✍ CIBA Foundation Symposium

Ethnobotany And The Search For New Drugs Book PDF
✏Book Title : Ethnobotany and the Search for New Drugs
✏Author : CIBA Foundation Symposium
✏Publisher : Wiley
✏Release Date : 1994-12-20
✏Pages : 290
✏ISBN : 0471950246
✏Available Language : English, Spanish, And French

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✏Ethnobotany and the Search for New Drugs Book Summary : A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to their knowledge and provision of rare plants which are used for some of the most potent drugs in Western medicine.

📒Natural Products And Drug Development ✍ Povl Krogsgaard-Larsen

Natural Products And Drug Development Book PDF
✏Book Title : Natural Products and Drug Development
✏Author : Povl Krogsgaard-Larsen
✏Publisher : Raven Press
✏Release Date : 1984
✏Pages : 559
✏ISBN : UOM:39015009541122
✏Available Language : English, Spanish, And French

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✏Natural Products and Drug Development Book Summary : This volume presents a survey of the development of bioactive compounds from natural sources. Major areas covered include terrestrial and marine sources for active constituents and lead structures; natural products as experimental tools and leads in drug design; antimicrobial and antitumor compounds; and natural products in drug development.

Science Culture Book PDF
✏Book Title : Science Culture
✏Author :
✏Publisher :
✏Release Date : 2002
✏Pages :
✏ISBN : UOM:39015078450296
✏Available Language : English, Spanish, And French

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✏Science Culture Book Summary :

📒Journal Of The Franklin Institute ✍ Franklin Institute (Philadelphia, Pa.)

Journal Of The Franklin Institute Book PDF
✏Book Title : Journal of the Franklin Institute
✏Author : Franklin Institute (Philadelphia, Pa.)
✏Publisher :
✏Release Date : 1826
✏Pages :
✏ISBN : STANFORD:36105000671698
✏Available Language : English, Spanish, And French

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✏Journal of the Franklin Institute Book Summary : Vols. 1-69 include more or less complete patent reports of the U.S. Patent Office for years 1825-59. Cf. Index to v. 1-120 of the Journal, p. [415].

Cancer Investigation Book PDF
✏Book Title : Cancer Investigation
✏Author :
✏Publisher :
✏Release Date : 1999
✏Pages :
✏ISBN : UCLA:L0081629396
✏Available Language : English, Spanish, And French

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✏Cancer Investigation Book Summary :

Comprehensive Medicinal Chemistry Ii Volume 1 Book PDF
✏Book Title : Comprehensive Medicinal Chemistry II Volume 1
✏Author : Peter Kennewell
✏Publisher : Elsevier Science
✏Release Date : 2006-11-15
✏Pages : 881
✏ISBN : 0080445144
✏Available Language : English, Spanish, And French

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✏Comprehensive Medicinal Chemistry II Volume 1 Book Summary : This volume provides and educative and authoriative discussions on the drug discovery and development process. It is divided into ten sections and starts with personal recollections on the history and evolution of the drug discovery process. To illustrate the end result of the drug discovery process, a large chapter reviews the major drug introductions over 1993-2003. Subsequent chapters examine the impact of genomic technologies, new sources of drugs and alternatives to animal testing. The next section reviews the roles of enterprise and pharamaceuticals companies, venture capitalists and academic-industrial relations in the drug discovery process. Social and ethical issues are reviewed in the context of assessing health demands in developed, developing countries and also in relation to smaller scale diseases (orphan drugs). Two chapters then review the bioethical and ethical issues facing the pharmaceutical industry. The volume concludes with reviews on funding and regulartion and how intellectual property rights and patents are protected. With such a wide variety of topics this volume will appeal to both scientists and non-scientists who need to understand how and why the pharmaceutical industry works. * valuable content available from May 2009 as an individual volume * provides a global overview of the drug discovery process

📒Journal Of The Chemical Society Of Pakistan ✍ Chemical Society of Pakistan

Journal Of The Chemical Society Of Pakistan Book PDF
✏Book Title : Journal of the Chemical Society of Pakistan
✏Author : Chemical Society of Pakistan
✏Publisher :
✏Release Date : 2006
✏Pages :
✏ISBN : CHI:76218249
✏Available Language : English, Spanish, And French

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✏Journal of the Chemical Society of Pakistan Book Summary :

📒Diabetes Mellitus Epidemic Combat The Challenge ✍ Asian Network of Research on Antidiabetic Plants. International Seminar

Diabetes Mellitus Epidemic Combat The Challenge Book PDF
✏Book Title : Diabetes Mellitus Epidemic Combat the Challenge
✏Author : Asian Network of Research on Antidiabetic Plants. International Seminar
✏Publisher : TATA McGraw-Hill Publishing Company
✏Release Date : 2005
✏Pages : 207
✏ISBN : CHI:74948611
✏Available Language : English, Spanish, And French

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✏Diabetes Mellitus Epidemic Combat the Challenge Book Summary : Contributed articles presented at the fourth International Seminar of Asian Network of Research on Antidiabetic Plants.

📒Natural Products ✍ Nancy Mulford

Natural Products Book PDF
✏Book Title : Natural Products
✏Author : Nancy Mulford
✏Publisher :
✏Release Date : 1995
✏Pages : 339
✏ISBN : UCSD:31822023768492
✏Available Language : English, Spanish, And French

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✏Natural Products Book Summary :

Classic Botanical Reprints 227 238 Book PDF
✏Book Title : Classic Botanical Reprints 227 238
✏Author :
✏Publisher :
✏Release Date : 199?
✏Pages :
✏ISBN : CORNELL:31924074267372
✏Available Language : English, Spanish, And French

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✏Classic Botanical Reprints 227 238 Book Summary :

Progress In Drug Research Book PDF
✏Book Title : Progress in Drug Research
✏Author :
✏Publisher :
✏Release Date : 1968
✏Pages :
✏ISBN : UCAL:B3734737
✏Available Language : English, Spanish, And French

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✏Progress in Drug Research Book Summary :

📒New Vistas In Therapeutics ✍ New York Academy of Sciences

New Vistas In Therapeutics Book PDF
✏Book Title : New Vistas in Therapeutics
✏Author : New York Academy of Sciences
✏Publisher :
✏Release Date : 2001
✏Pages : 253
✏ISBN : STANFORD:36105025782991
✏Available Language : English, Spanish, And French

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✏New Vistas in Therapeutics Book Summary : This text examines the history of drug discovery and development from natural products (medicinal) through directed combinatorial approaches. It concludes with an overview and discussion of the future of gene therapy.

📒Herbal Medicine ✍ Pravin Chandra Trivedi

Herbal Medicine Book PDF
✏Book Title : Herbal Medicine
✏Author : Pravin Chandra Trivedi
✏Publisher :
✏Release Date : 2006
✏Pages : 322
✏ISBN : STANFORD:36105129051699
✏Available Language : English, Spanish, And French

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✏Herbal Medicine Book Summary : In Spite Of Increasing Urbanisation, A Large Proportion Of The Indian Population Has Retained Its Reliance Upon The Traditional Approach To Healthcare And Continues To Consult Traditional Medicinal Practitioners (Tmps) For Medical Treatment. India Is Sitting On A Gold Mine Of Well-Recorded And Well-Practised Knowledge Of Traditional Herbal Medicine. Amongst The Ancient Civilisations, India Has Been Known To Be A Rich Repository Of Medicinal Plants. The Rig Veda, Yajur Veda And Atharva Veda And Later On, The Charaka Samhita And The Sushruta Samhita Described The Properties And Uses Of Plants In Compounding Of Drugs And These Are Still Used In Classical Formulations. The Present Book Herbal Medicine: Traditional Practices Contains 17 Articles On Different Aspects Of The Subject. The Book Incorporates Articles On Traditional Phytotherapy For Jaundice; Medicinal Plants Used Against Gynaecological Morbidity; Indigenous Knowledge For Curing And Preventing Paediatric Diseases; Herbal Traditional Medicine For Sensory Organ Diseases And Other Ethnomedicinal Plants Used By Tribals Of India. Articles On Recent Approaches In The Development And Standardisation Of Formulations Of Herbal Drugs And The Role Of Biotechnology In Their Upgradation Provide Excellent Information On The Topic. The Book Also Covers Topics On Conservation Of Medicinal Plants In India, Strategy For Development Of Medicinal And Aromatic Plants And Application Of Industrial Wastes For Growth Of Medicinal And Aromatic Plants. Articles On Traditional Knowledge System About Veterinary Health Care Provide Information On Plants Used For Curing Animal Diseases. In Addition, General Articles Namely Soma Plants; Botanical Enigma And Hypoglycaemic Impact Of Spirulina Algae Have Added To The Value Of The Book. The Present Book Provides Excellent Glimpses Of The Rich Herbal Medicine And Traditional Knowledge Heritage Of India. The Present Book Will Serve Not Only As An Excellent Reference Material But Also As A Practical Guide For Herbal Healers, Vaidyas, Hakims, Research Workers And Students In The Field Of Medicinal Plants.

Chemistry And Industry Book PDF
✏Book Title : Chemistry and Industry
✏Author :
✏Publisher :
✏Release Date : 1999
✏Pages :
✏ISBN : UCSD:31822022712822
✏Available Language : English, Spanish, And French

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✏Chemistry and Industry Book Summary :