Diffusion Mri And Microstructure

Assessing Cellular Microstructure In Biological Tissues Using In Vivo Diffusion Weighted Magnetic Resonance Book PDF
✏Book Title : Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion Weighted Magnetic Resonance
✏Author : Julien Valette
✏Publisher : Frontiers Media SA
✏Release Date : 2019-05-16
✏Pages :
✏ISBN : 9782889458417
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion Weighted Magnetic Resonance Book Summary : Magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques have opened new doors for examining biological tissues in vivo. By combining sensitization to diffusion using magnetic field gradients with a variety of imaging and localization schemes, diffusion-weighted MRI and diffusion-weighted MRS allow investigating translational diffusion of endogenous molecules, such as water or metabolites, in biological tissues, most commonly the brain but also other organs such as the prostate. The typical voxel resolution of MRI or MRS is in the millimeter to centimeter range, much lower than the cellular scale. However, as molecules are typically diffusing over just a few µm during the duration of the measurement (the “diffusion time”) and encounter numerous biological membranes at these scales, the average cellular microstructure has a critical influence on the measured diffusion signal. Hence, diffusion-weighted MRI and diffusion-weighted MRS are sensitive to tissue microstructure at a scale well below the nominal imaging resolution. However, the connection between diffusion properties and tissue microstructure remains indirect, so any attempt to quantify microstructure will rely on modeling. The goal of this Research Topic was to gather experts in various acquisition and modeling strategies and show how these approaches, despite their own strengths and weaknesses, can yield unique information about cellular microstructure, and sometimes complement each other.

Diffusion Mri For Well Posed And Optimal White Matter Microstructure Characterisation Book PDF
✏Book Title : Diffusion MRI for Well posed and Optimal White Matter Microstructure Characterisation
✏Author : Santiago Coelho
✏Publisher :
✏Release Date : 2019
✏Pages :
✏ISBN : OCLC:1144720058
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Diffusion MRI for Well posed and Optimal White Matter Microstructure Characterisation Book Summary :

📒Diffusion Mri ✍ Heidi Johansen-Berg

Diffusion Mri Book PDF
✏Book Title : Diffusion MRI
✏Author : Heidi Johansen-Berg
✏Publisher : Academic Press
✏Release Date : 2009-04-28
✏Pages : 502
✏ISBN : 0080878512
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Diffusion MRI Book Summary : Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments. The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder. • Discusses all aspects of a diffusion MRI study from acquisition, through analysis, to interpretation, providing an essential reference text for scientists designing or interpreting diffusion MR experiments • Practical advice on running an experiment • Full color throughout

Characterization Of Microstructures With Diffusion Mri Book PDF
✏Book Title : Characterization of Microstructures with Diffusion MRI
✏Author : Marco Bertleff
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1026406335
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Characterization of Microstructures with Diffusion MRI Book Summary :

📒Computational Diffusion Mri ✍ Elisenda Bonet-Carne

Computational Diffusion Mri Book PDF
✏Book Title : Computational Diffusion MRI
✏Author : Elisenda Bonet-Carne
✏Publisher : Springer
✏Release Date : 2019-04-23
✏Pages : 390
✏ISBN : 9783030058319
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Computational Diffusion MRI Book Summary : This volume gathers papers presented at the Workshop on Computational Diffusion MRI (CDMRI’18), which was held under the auspices of the International Conference on Medical Image Computing and Computer Assisted Intervention in Granada, Spain on September 20, 2018. It presents the latest developments in the highly active and rapidly growing field of diffusion MRI. The reader will find papers on a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in-vivo recovery of microstructural and connectivity features, as well as harmonisation and frontline applications in research and clinical practice. The respective papers constitute invited works from high-profile researchers with a specific focus on three topics that are now gaining momentum within the diffusion MRI community: i) machine learning for diffusion MRI; ii) diffusion MRI outside the brain (e.g. in the placenta); and iii) diffusion MRI for multimodal imaging. The book shares new perspectives on the latest research challenges for those currently working in the field, but also offers a valuable starting point for anyone interested in learning computational techniques in diffusion MRI. It includes rigorous mathematical derivations, a wealth of full-colour visualisations, and clinically relevant results. As such, it will be of interest to researchers and practitioners in the fields of computer science, MRI physics and applied mathematics alike.

The Effect Of Tumour Microstructure On Diffusion Weighted Mri Measurements Book PDF
✏Book Title : The Effect of Tumour Microstructure on Diffusion weighted MRI Measurements
✏Author : Damien Joseph McHugh
✏Publisher :
✏Release Date : 2015
✏Pages :
✏ISBN : OCLC:1064555487
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏The Effect of Tumour Microstructure on Diffusion weighted MRI Measurements Book Summary :

📒Diffusion Tensor Imaging ✍ Wim Van Hecke

Diffusion Tensor Imaging Book PDF
✏Book Title : Diffusion Tensor Imaging
✏Author : Wim Van Hecke
✏Publisher : Springer
✏Release Date : 2015-12-14
✏Pages : 440
✏ISBN : 9781493931187
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Diffusion Tensor Imaging Book Summary : This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally. DTI is a non-invasive magnetic resonance imaging (MRI) technique for visualizing and quantifying tissue microstructure based on diffusion. The book discusses the theoretical background underlying DTI and advanced techniques based on higher-order models and multi-shell diffusion imaging. It covers the practical implementation of DTI; derivation of information from DTI data; and a range of clinical applications, including neurosurgical planning and the assessment of brain tumors. Its practical utility is enhanced by decision schemes and a fully annotated DTI brain atlas, including color fractional anisotropy maps and 3D tractography reconstructions of major white matter fiber bundles. Featuring contributions from leading specialists in the field of DTI, Diffusion Tensor Imaging: A Practical Handbook is a valuable resource for radiologists, neuroradiologists, MRI technicians and clinicians.

Diffusion Encoding Waveform Design For Mapping Microstructure In The Human Brain Book PDF
✏Book Title : Diffusion Encoding Waveform Design for Mapping Microstructure in the Human Brain
✏Author : Grant Kaijuin Yang
✏Publisher :
✏Release Date : 2019
✏Pages :
✏ISBN : OCLC:1117555345
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Diffusion Encoding Waveform Design for Mapping Microstructure in the Human Brain Book Summary : Diffusion MRI is a non-invasive method of measuring the diffusion of water molecules in biological tissue. The patterns of water diffusion reflect the underlying tissue microstructure, which hinders or restricts the displacement of water. Changes in diffusion reflect microstructural changes that can be critical for clinical diagnosis, disease monitoring, and the study of neurodegenerative processes. The diffusive motion of water is encoded through the interaction of time-varying magnetic field gradients and the diffusive motion of water molecules. The design of these gradient waveforms can be tailored to the diffusion regime of interest and the capabilities of the MR scanner. Diffusion gradient waveforms can be designed to separate the effects of tissue heterogeneity, orientation dispersion, and microscopic diffusion anisotropy within the constraints of the limitations and imperfections of the gradient systems. In this dissertation, a parsimonious sampling scheme for double diffusion encoding (DDE) MRI is presented, which optimizes the measurement of microscopic diffusion anisotropy on a whole- body clinical MRI scanner. The proposed scheme was used to demonstrate the improved ability of DDE compared to conventional MRI to characterize normal and damaged tissue in a cohort of multiple sclerosis patients. Next, an optimization framework is presented for the design of generalized diffusion encoding waveforms which are robust to imperfections in the gradient system caused by eddy current and concomitant fields. Finally, the adaptation of these methods to a novel high- performance head-only gradient system is described.

Visualization And Processing Of Tensor Fields Book PDF
✏Book Title : Visualization and Processing of Tensor Fields
✏Author : David H. Laidlaw
✏Publisher : Springer Science & Business Media
✏Release Date : 2009-03-30
✏Pages : 376
✏ISBN : 9783540883784
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Visualization and Processing of Tensor Fields Book Summary : This book provides researchers an inspirational look at how to process and visualize complicated 2D and 3D images known as tensor fields. With numerous color figures, it details both the underlying mathematics and the applications of tensor fields.

Investigating Microstructure In The Brain Using Diffusion Weighted Magnetic Resonance Imaging Book PDF
✏Book Title : Investigating Microstructure in the Brain Using Diffusion Weighted Magnetic Resonance Imaging
✏Author : Seyed Hamed Yousefi Mesri
✏Publisher :
✏Release Date : 2014
✏Pages : 136
✏ISBN : OCLC:1038062010
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Investigating Microstructure in the Brain Using Diffusion Weighted Magnetic Resonance Imaging Book Summary :

Visualization And Processing Of Tensor Fields Book PDF
✏Book Title : Visualization and Processing of Tensor Fields
✏Author : Joachim Weickert
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-06-25
✏Pages : 481
✏ISBN : 9783540312727
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Visualization and Processing of Tensor Fields Book Summary : Matrix-valued data sets – so-called second order tensor fields – have gained significant importance in scientific visualization and image processing due to recent developments such as diffusion tensor imaging. This book is the first edited volume that presents the state of the art in the visualization and processing of tensor fields. It contains some longer chapters dedicated to surveys and tutorials of specific topics, as well as a great deal of original work by leading experts that has not been published before. It serves as an overview for the inquiring scientist, as a basic foundation for developers and practitioners, and as as a textbook for specialized classes and seminars for graduate and doctoral students.

Evaluation Of Myocardial Microstructure In Congenital Heart Diseases With Diffusion Magnetic Resonance Imaging Book PDF
✏Book Title : Evaluation of Myocardial Microstructure in Congenital Heart Diseases with Diffusion Magnetic Resonance Imaging
✏Author : Cyril Tous
✏Publisher :
✏Release Date : 2019
✏Pages : 1086
✏ISBN : OCLC:1131906562
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Evaluation of Myocardial Microstructure in Congenital Heart Diseases with Diffusion Magnetic Resonance Imaging Book Summary : New Zealand has a long history with studying congenital heart disease (CHD) and has one of the oldest collections of hearts that dates back to the 1950s. These pathological specimens can provide insight into the characteristics of CHD across particular patient groups. The work in this thesis details the development of MRI diffusion sequences and analysis techniques to assess myocardial fibre structure in these long-term fixed specimens. These techniques are then used to characterise the differences in fibre structure between specimens with different types of CHD. Tissues fixed in formalin for long periods of time have severely shortened T2. Commonly available diffusion imaging strategies on standard clinical MRI systems are unsuitable for use in these specimens. We developed and tested four candidate pulse sequences to overcome the limitations in short T2 specimens. A single spin echo pulse sequence using monopolar diffusion encoding gradients was found to be most suitable to provide the necessary diffusion weighting while minimise T2-related signal loss. After selecting an appropriate image acquisition strategy, a suitable post-processing pipeline to analyse the images and quantify cardiac diffusion metrics associated with fibre structure was required. We compared different regularization techniques using simulated cardiac diffusion imaging data to find a suitable techinque for the low-signal images expected from fixed specimens. Linear least-squares methods were found to be suitable to estimate cardiac diffusion metrics such as the helix angle, and transverse angle, even in noisy image data. We also present a technique for estimating the helix angle gradient across the heart wall and the asymmetry of the helix angle distribution. The acquisition and analysis techniques were subsequently used to assess the differences in fibre structure between different groups of CHD specimens. We assess the cardiac diffusion metrics in specimens with tetralogy of Fallot (TOF, n=10), dextrotransposition of the great arteries (dTGA, n=8), and systemic right ventricles (n=4). Two additional cases with unique pathology, one with situs inversus totalis and one with levo-transposition of the great arteries (lTGA) were also included. Our results show that the presence of ventricular septal defects (VSD) decrease the helix angle gradient in the septum, which is consistent with observations using other techniques. The presence of a VSD was also associated with a decreased helix angle gradient in the RV wall which correspond to the predominant circumferential fibres. In the TOF specimens, the helix angle gradient differed near the RV-LV junction and in the RV wall between cases with bicuspid or tricuspid pulmonary valves. The sheet angle in the septum of the TOF specimens was opposite to the sheet angles in the LV free wall. Systemic right ventricle had mainly circumferential myocytes. The helix angle variation in the single case of SIT was linear, asymmetric, and reversed until a transition zone near the epicardium. In conclusion, segment-wise myoarchitecture features in different types of heart defects could be associated with the cardiac dysfunctions that are observed clinically in congenital heart disease patients.

Computational Diffusion Mri Book PDF
✏Book Title : Computational Diffusion MRI
✏Author : Andrea Fuster
✏Publisher : Springer
✏Release Date : 2016-04-08
✏Pages : 234
✏ISBN : 9783319285887
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Computational Diffusion MRI Book Summary : These Proceedings of the 2015 MICCAI Workshop “Computational Diffusion MRI” offer a snapshot of the current state of the art on a broad range of topics within the highly active and growing field of diffusion MRI. The topics vary from fundamental theoretical work on mathematical modeling, to the development and evaluation of robust algorithms, new computational methods applied to diffusion magnetic resonance imaging data, and applications in neuroscientific studies and clinical practice. Over the last decade interest in diffusion MRI has exploded. The technique provides unique insights into the microstructure of living tissue and enables in-vivo connectivity mapping of the brain. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into clinical practice. New processing methods are essential for addressing issues at each stage of the diffusion MRI pipeline: acquisition, reconstruction, modeling and model fitting, image processing, fiber tracking, connectivity mapping, visualization, group studies and inference. This volume, which includes both careful mathematical derivations and a wealth of rich, full-color visualizations and biologically or clinically relevant results, offers a valuable starting point for anyone interested in learning about computational diffusion MRI and mathematical methods for mapping brain connectivity, as well as new perspectives and insights on current research challenges for those currently working in the field. It will be of interest to researchers and practitioners in the fields of computer science, MR physics, and applied mathematics.​

Advanced Diffusion Encoding Methods In Mri Book PDF
✏Book Title : Advanced Diffusion Encoding Methods in MRI
✏Author : Daniel Topgaard
✏Publisher : Royal Society of Chemistry
✏Release Date : 2020-08-17
✏Pages : 436
✏ISBN : 9781788017268
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Advanced Diffusion Encoding Methods in MRI Book Summary : The medical MRI community is by far the largest user of diffusion NMR techniques and this book captures the current surge of methods and provides a primary source to aid adoption in this field. There is a trend to adapting the more advanced diffusion encoding sequences developed by NMR researchers within the fields of porous media, chemical engineering, and colloid science to medical research. Recently published papers indicate great potential for improved diagnosis of the numerous pathological conditions associated with changes of tissue microstructure that are invisible to conventional diffusion MRI. This book disseminates these recent developments to the wider community of MRI researchers and clinicians. The chapters cover the theoretical basis, hardware and pulse sequences, data analysis and validation, and recent applications aimed at promoting further growth in the field. This is a fast moving field and chapters are written by key MRI scientists that have contributed to the successful translation of the advanced diffusion NMR methods to the context of medical MRI, from global locations.

Model Based Analysis Of Myocardial Microstructure For Left Ventricular Mechanics Using Mri Book PDF
✏Book Title : Model based Analysis of Myocardial Microstructure for Left Ventricular Mechanics Using MRI
✏Author : Bianca Freytag
✏Publisher :
✏Release Date : 2020
✏Pages : 314
✏ISBN : OCLC:1200779563
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Model based Analysis of Myocardial Microstructure for Left Ventricular Mechanics Using MRI Book Summary : Heart disease is the leading cause of morbidity and mortality in the western world. The underlying mechanisms of heart failure (HF) remain largely unexplained. Increased myocardial tissue stiffness, diffuse fibrosis, and tissue remodelling have been identified as contributors to HF. However, their biomechanical effects are not well understood. In this thesis, the link between intrinsic mechanical properties of the myocardium, estimated using an inverse finite element approach, and indices of fibrosis quantified from T1 magnetic resonance imaging (MRI) was investigated using patient data. No significant correlation was found between intrinsic myocardial stiffness and native or post-contrast T1 times. Another important determinant of left ventricular (LV) function is the microstructural tissue organisation. A statistical analysis of microstructural orientations and myofibre disarray derived from diffusion-weighted magnetic resonance imaging (DWI) of healthy rats and end-stage spontaneously hypertensive rats was conducted. No evidence of remodelling of orientations or increased global myofibre disarray was found in the diseased rats, but hypertension did affect regional disarray. Hypertension had no significant effect on the transmural distributions of primary or secondary eigenvectors of the diffusion tensors. Model-based parameterisations were developed to fit microstructural orientations directly to diffusion tensors, or to raw diffusion signals. These methods avoid the need to perform eigenanalysis on the diffusion tensor, or, when fitting to raw diffusion signals, eliminate the need to compute diffusion tensors using least squares fitting. Cardiac mechanics simulations are sensitive to the representation of microstructural orientations, as well as other factors such as loading conditions and kinematic constraints. To investigate the effects that variations in the microstructural orientation fields have on LV mechanics, a region of indifference was constructed around the helix angle field parameters that best represent a high resolution DWI dataset of a canine heart. This indifference region defines the field parameters to which the goodness-of-fit is insensitive to. A set of perturbed helix angle fields was determined from the decomposition of the indifference region, and the perturbations were used to describe the microstructural orientations in passive and contractile mechanics simulations. Passive mechanics predictions were found to be insensitive to variation in helix angle parameters, but end-systolic predictions of ventricular geometry were substantially affected. This thesis demonstrated the use of computational model-based analyses of myocardial microstructure, assessed through MRI, to provide tissue-specific evaluation of LV mechanical function and microstructural remodelling. A particular emphasis is placed on the role of myocardial fibrosis, intrinsic myocardial stiffness, and microstructural orientations.

📒Computational Diffusion Mri ✍ Lauren O'Donnell

Computational Diffusion Mri Book PDF
✏Book Title : Computational Diffusion MRI
✏Author : Lauren O'Donnell
✏Publisher : Springer
✏Release Date : 2015-02-17
✏Pages : 219
✏ISBN : 9783319111827
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Computational Diffusion MRI Book Summary : This book contains papers presented at the 2014 MICCAI Workshop on Computational Diffusion MRI, CDMRI’14. Detailing new computational methods applied to diffusion magnetic resonance imaging data, it offers readers a snapshot of the current state of the art and covers a wide range of topics from fundamental theoretical work on mathematical modeling to the development and evaluation of robust algorithms and applications in neuroscientific studies and clinical practice. Inside, readers will find information on brain network analysis, mathematical modeling for clinical applications, tissue microstructure imaging, super-resolution methods, signal reconstruction, visualization, and more. Contributions include both careful mathematical derivations and a large number of rich full-color visualizations. Computational techniques are key to the continued success and development of diffusion MRI and to its widespread transfer into the clinic. This volume will offer a valuable starting point for anyone interested in learning computational diffusion MRI. It also offers new perspectives and insights on current research challenges for those currently in the field. The book will be of interest to researchers and practitioners in computer science, MR physics, and applied mathematics.

Information Processing In Medical Imaging Book PDF
✏Book Title : Information Processing in Medical Imaging
✏Author : Gary E. Christensen
✏Publisher : Springer Science & Business Media
✏Release Date : 2005-06-24
✏Pages : 777
✏ISBN : 3540265457
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Information Processing in Medical Imaging Book Summary : This book constitutes the refeered proceedings of the 19th International Conference on Information Processing in Medical Imaging, IPMI 2005, held in Glenwood Springs, Colorado, in July 2005. The 63 revised full papers presented were carefully reviewed and selected from 245 submissions. The papers are organized in topical sections on shape and population modeling, diffusion tensor imaging and functional magnetic resonance, segmentation and filtering, small animal imaging, surfaces and segmentation, applications, image registration, registration and segmentation.

📒Health Information Science ✍ Yanchun Zhang

Health Information Science Book PDF
✏Book Title : Health Information Science
✏Author : Yanchun Zhang
✏Publisher : Springer
✏Release Date : 2014-04-02
✏Pages : 282
✏ISBN : 9783319062693
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Health Information Science Book Summary : This book constitutes the refereed proceedings of the Third International Conference on Health Information Science, HIS 2014, held in Shenzhen, China, in April 2014. The 29 full papers presented were carefully reviewed and selected from 61 submissions. They cover a wide range of topics in health information sciences and systems that support the health information management and health service delivery. They deal with medical/health/biomedicine information resources, such as patient medical records, devices and equipments, software and tools to capture, store, retrieve, process, analyse, and optimize the use of information in the health domain; data management, data mining, and knowledge discovery, all of which play a key role in the decision making, management of public health, examination of standards, privacy and security issues; computer visualization and artificial intelligence for computer-aided diagnosis; and development of new architectures and applications for health information systems.

A Computational Model To Understand The Relationship Between Cardiac Microstructure And Diffusion Mri  Book PDF
✏Book Title : A Computational Model to Understand the Relationship Between Cardiac Microstructure and Diffusion MRI
✏Author : Joanne Bates
✏Publisher :
✏Release Date : 2016
✏Pages :
✏ISBN : OCLC:1063736677
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏A Computational Model to Understand the Relationship Between Cardiac Microstructure and Diffusion MRI Book Summary :

📒Advances In Diffusion Mri ✍ Jose Manuel Guerrero Gonzalez

Advances In Diffusion Mri Book PDF
✏Book Title : Advances in Diffusion MRI
✏Author : Jose Manuel Guerrero Gonzalez
✏Publisher :
✏Release Date : 2020
✏Pages : 203
✏ISBN : OCLC:1190590602
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Advances in Diffusion MRI Book Summary : Diffusion-weighted MRI (dMRI) represents a well-established field for the study of micro-structure in tissue and other porous media. Yet, the pipeline from image acquisition to analysis and application of imaging markers is dynamic and components within it are ever evolving. The field continues to enthuse researchers to extend, refine, and create imaging instruments as well as data processing and analysis methods. It is in this spirit that this work set out to improve - or augment to - the dMRI pipeline in areas associated with modeling, analysis, and validation. Biophysical models represent an important instrument for establishing links between the dMRI signal and biological properties of tissue microstructure. However, due to the number of parameters needed to faithfully describe the signal in terms of the complex tissue micro-architecture, biophysical modeling methods need to rely on assumptions that are often oversimplifying. One component of this work conducted an empirical study of the model in Neurite Orientation Dispersion and Density Imaging (NODDI) regarding assumptions for the intra-cellular parallel intrinsic diffusivity. Understanding individual variability of dMRI-based markers is an important task when studying conditions with high inter-subject heterogeneity such as traumatic brain injury and autism. A second component of this work focused on developing a framework based on the Mahalanobis Distance, as a multivariate approach for individualized evaluation of imaging-based measures. Validation of apparent diffusion coefficients (ADCs) estimated from dMRI measurements requires the use of test media with known diffusion coefficients as well as their temperature dependence. A third component of this work sought to develop a test object (phantom) constructed from liquids whose diffusion constants at multiple temperatures were previously characterized. Models of the diffusion-temperature relationships where investigated for their potential use in estimating the temperature of the phantom from dMRI measurements.

The Effects Of Ageing On Mouse Muscle Microstructure A Comparative Study Of Time Dependent Diffusion Mri And Histological Assessment Book PDF
✏Book Title : The Effects of Ageing on Mouse Muscle Microstructure a Comparative Study of Time dependent Diffusion MRI and Histological Assessment
✏Author :
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1032132084
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏The Effects of Ageing on Mouse Muscle Microstructure a Comparative Study of Time dependent Diffusion MRI and Histological Assessment Book Summary :

Handbook Of Research On Advanced Techniques In Diagnostic Imaging And Biomedical Applications Book PDF
✏Book Title : Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications
✏Author : Exarchos, Themis P.
✏Publisher : IGI Global
✏Release Date : 2009-04-30
✏Pages : 598
✏ISBN : 9781605663159
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications Book Summary : "This book includes state-of-the-art methodologies that introduce biomedical imaging in decision support systems and their applications in clinical practice"--Provided by publisher.

Principles And Practice Of Movement Disorders E Book Book PDF
✏Book Title : Principles and Practice of Movement Disorders E Book
✏Author : Stanley Fahn
✏Publisher : Elsevier Health Sciences
✏Release Date : 2011-08-09
✏Pages : 556
✏ISBN : 9781437737707
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Principles and Practice of Movement Disorders E Book Book Summary : Principles and Practice of Movement Disorders provides the complete, expert guidance you need to diagnose and manage these challenging conditions. Drs. Stanley Fahn, Joseph Jankovic and Mark Hallett explore all facets of these disorders, including the latest rating scales for clinical research, neurochemistry, clinical pharmacology, genetics, clinical trials, and experimental therapeutics. This edition features many new full-color images, additional coverage of pediatric disorders, updated Parkinson information, and many other valuable updates. An accompanying Expert Consult website makes the content fully searchable and contains several hundred video clips that illustrate the manifestations of all the movement disorders in the book along with their differential diagnoses. Get just the information you need for a clinical approach to diagnosis and management, with minimal emphasis on basic science. Find the answers you need quickly and easily thanks to a reader-friendly full-color format, with plentiful diagrams, photographs, and tables. Apply the latest advances to diagnosis and treatment of pediatric movement disorders, Parkinson disease, and much more. View the characteristic presentation of each disorder with a complete collection of professional-quality, narrated videos online. Better visualize every concept with new full-color illustrations throughout. Search the complete text online, follow links to PubMed abstracts, and download all of the illustrations, at www.expertconsult.com.

Computational Diffusion Mri Book PDF
✏Book Title : Computational Diffusion MRI
✏Author : Enrico Kaden
✏Publisher : Springer
✏Release Date : 2018-04-02
✏Pages : 245
✏ISBN : 9783319738390
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Computational Diffusion MRI Book Summary : This volume presents the latest developments in the highly active and rapidly growing field of diffusion MRI. The reader will find numerous contributions covering a broad range of topics, from the mathematical foundations of the diffusion process and signal generation, to new computational methods and estimation techniques for the in-vivo recovery of microstructural and connectivity features, as well as frontline applications in neuroscience research and clinical practice. These proceedings contain the papers presented at the 2017 MICCAI Workshop on Computational Diffusion MRI (CDMRI’17) held in Québec, Canada on September 10, 2017, sharing new perspectives on the most recent research challenges for those currently working in the field, but also offering a valuable starting point for anyone interested in learning computational techniques in diffusion MRI. This book includes rigorous mathematical derivations, a large number of rich, full-colour visualisations and clinically relevant results. As such, it will be of interest to researchers and practitioners in the fields of computer science, MRI physics and applied mathematics.

Microbes And Microstructure Book PDF
✏Book Title : Microbes and Microstructure
✏Author : Nicholas Vogt
✏Publisher :
✏Release Date : 2020
✏Pages : 97
✏ISBN : OCLC:1161988850
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Microbes and Microstructure Book Summary : Alzheimer's disease (AD) currently has no prevention, treatment, or cure, and the etiology of this devasting neurodegenerative disease remains largely unclear, despite decades of research. In order to combat the significant challenges posed by AD, it will be critical to improve our understanding of factors that contribute to disease as well as to develop sensitive markers of early pathological changes. Towards this end, the work included in this dissertation focused on the role of the gut microbiome in AD, as well as the use of advanced multi-shell diffusion-weighted MRI to characterize cortical microstructural alterations in preclinical and clinical AD. In Chapter 1, we performed the first comprehensive survey of gut microbiota in individuals with AD and revealed broad-scale alterations in gut bacterial composition in individuals with AD. Moreover, we also found that gut bacterial taxa that are altered in AD correlate with cerebrospinal fluid (CSF) biomarkers of AD pathology, even in cognitively unimpaired individuals. In Chapter 2, we found that the gut microbiota-derived metabolite trimethylamine N-oxide (TMAO), which has been linked to brain aging and cognitive impairment in mice, is elevated in the CSF of individuals with AD and mild cognitive impairment (MCI), and that levels of CSF TMAO correlate with markers of AD pathology and neurodegeneration. In Chapter 3, we used neurite orientation dispersion and density imaging (NODDI), a multi-compartment diffusion-weighted imaging (DWI) model, to show that cortical NODDI metrics are altered in individuals with MCI and AD. Notably, for individuals with MCI, several key brain regions showed changes in cortical microstructure but not cortical thickness. In Chapter 4, we extended this work into the preclinical stage of AD and found a non-monotonic relationship between AD pathology and cortical neurite density, but not cortical thickness, suggesting that NODDI metrics are more sensitive markers of early neurodegenerative changes than conventional T1-weighted MRI measurements. Overall, the work included in this dissertation contributes to addressing the enormous problem of AD by furthering our growing understanding of the role of gut microbiota in AD, as well as highlighting the utility of NODDI metrics in detecting early cortical microstructural changes.

Advances In Neonatal Neurology An Issue Of Clinics In Perinatology  Book PDF
✏Book Title : Advances in Neonatal Neurology An Issue of Clinics in Perinatology
✏Author : Praveen Ballabh
✏Publisher : Elsevier Health Sciences
✏Release Date : 2014-02-22
✏Pages : 321
✏ISBN : 9780323296212
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Advances in Neonatal Neurology An Issue of Clinics in Perinatology Book Summary : The 16 articles in this issue draw on the expertise of internationally recognized experts who have collectively provided cross-cutting reviews with a broad perspective on the current state of the field. The authors have provided succinct, up-to-date clinical perspectives and highlight current controversies and future challenges. As a result, this issue is a cutting-edge compendium of this complex and fast-moving field. Throughout the issue, the reader is encouraged to acquire a more comprehensive perspective by drawing connections between earlier and later articles that are thematically grouped around issues dealing with pathogenesis, diagnosis, and therapy. This issue underscores the vital importance of continued support to encourage and nurture collaboration among clinicians and scientists.

Caffey S Pediatric Diagnostic Imaging E Book Book PDF
✏Book Title : Caffey s Pediatric Diagnostic Imaging E Book
✏Author : Brian D. Coley
✏Publisher : Elsevier Health Sciences
✏Release Date : 2013-05-21
✏Pages : 1784
✏ISBN : 9781455753604
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Caffey s Pediatric Diagnostic Imaging E Book Book Summary : Since 1945, radiologists have turned to Caffey's Pediatric Diagnostic Imaging for the most comprehensive coverage and unparalleled guidance in all areas of pediatric radiology. Continuing this tradition of excellence, the completely revised 12th edition - now more concise yet still complete - focuses on the core issues you need to understand new protocols and sequences, and know what techniques are most appropriate for given clinical situations. "This text will obviously be of great interest not only to radiologists, also to those who work with children including all pediatric specialties. It is also extremely useful in countries with resource poor setting where there is shortage of well-trained radiologists in pediatric specialties." Reviewed by: Yangon Children Hospital on behalf of the Journal of the European Paediatric Neurology Society, January 2014 "This is a thoroughly up-to-date text, divided into manageable topics, at a very reasonable price and I thoroughly recommend it to anyone who needs updating in the field of paediatrics or paediatric imaging." RAD, February 2014 Determine the best modality for each patient with state-of-the art discussions of the latest pediatric imaging techniques. Quickly grasp the fundamentals you need to know through a more precise, streamlined format, reorganized by systems and disease processes, as well as "Teaching Boxes" that highlight key points in each chapter. Apply all the latest pediatric advances in clinical fetal neonatology techniques, technology, and pharmacology. Achieve accurate diagnoses as safely as possible. Increased coverage of MRI findings and newer imaging techniques for all organ systems emphasizes imaging examination appropriateness and safety. Reap the fullest benefit from the latest neuroimaging techniques including diffusion tensor imaging, fMRI, and susceptibility weighted imaging. Keep current with the latest pediatric radiological knowledge and evidence-based practices. Comprehensive updates throughout include new and revised chapters on prenatal imaging; newer anatomic and functional imaging techniques (including advances in cardiac imaging); disease classifications and insights into imaging disease processes; and advanced imaging topics in neurological, thoracoabdominal, and musculoskeletal imaging. Compare your findings to more than 10,000 high-quality radiology images. Access the full text online at Expert Consult including illustrations, videos, and bonus online-only pediatric imaging content.

Clinical Applications Of Functional Mri An Issue Of Neuroimaging Clinics  Book PDF
✏Book Title : Clinical Applications of Functional MRI An Issue of Neuroimaging Clinics
✏Author : Jay J. Pillai
✏Publisher : Elsevier Health Sciences
✏Release Date : 2014-11-13
✏Pages : 193
✏ISBN : 9780323323840
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Clinical Applications of Functional MRI An Issue of Neuroimaging Clinics Book Summary : Editor Jay J. Pillai and authors review important areas in Clinical Applications of Functional MRI. Articles will include: Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging for Presurgical Planning; Visual Mapping Using Blood Oxygen Level Dependent Functional MRI; Applications of BOLD fMRI and DTI in Epilepsy; Pretherapeutic fMRI in Children; BOLD fMRI for Presurgical Planning; Brain Tensor Imaging for Brain Malformations: Does it Help?; Technical Considerations for fMRI Analysis; Special Considerations/Technical Limitations of BOLD fMRI; The Economics of Functional MRI: Clinical and Research; Memory Assessment in the Clinical Context Using fMRI: A Critical Look at the State of the Field; Resting State BOLD fMRI for Pre-surgical Planning, and more!

Mri Of The Knee An Issue Of Magnetic Resonance Imaging Clinics Of North America E Book Book PDF
✏Book Title : MRI of the Knee An Issue of Magnetic Resonance Imaging Clinics of North America E Book
✏Author : Kirkland W. Davis
✏Publisher : Elsevier Health Sciences
✏Release Date : 2014-11-13
✏Pages : 321
✏ISBN : 9780323323802
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏MRI of the Knee An Issue of Magnetic Resonance Imaging Clinics of North America E Book Book Summary : This issue, edited by Dr. Kirkland Davis, will comprehensively review imaging of the knee. Articles will include: Magnetic Resonance Imaging of the Meniscus; MRI of Cruciate Ligaments; Magnetic Resonance Imaging of the Extensor Mechanism; Quantitative Magnetic Resonance Imaging of the Articular Cartilage of the Knee Joint; Magnetic Resonance Imaging of the Pediatric Knee; MRI of Extra-Synovial Inflammation and Impingement about the Knee; A Biomechanical Approach to Interpreting MRI of Knee Injuries; MRI Assessment of Arthritis of the Knee; MRI of the Post-Operative Meniscus; MR Imaging of Cartilage Repair Procedures; Imaging the Knee in the Setting of Metal Hardware, and more!

Medical Imaging And Augmented Reality Book PDF
✏Book Title : Medical Imaging and Augmented Reality
✏Author : Guang-Zhong Yang
✏Publisher : Springer Science & Business Media
✏Release Date : 2004-08-11
✏Pages : 384
✏ISBN : 9783540228776
✏Available Language : English, Spanish, And French

Click Here To Get Book

✏Medical Imaging and Augmented Reality Book Summary : Rapid technical advances in medical imaging, including its growing application to drug/gene therapy and invasive/interventional procedures, have attracted significant interest in close integration of research in life sciences, medicine, physical sciences and engineering. This is motivated by the clinical and basic science research requi- ment of obtaining more detailed physiological and pathological information about the body for establishing localized genesis and progression of diseases. Current research is also motivated by the fact that medical imaging is increasingly moving from a primarily diagnostic modality towards a therapeutic and interventional aid, driven by recent advances in minimal-access and robotic-assisted surgery. It was our great pleasure to welcome the attendees to MIAR 2004, the 2nd Int- national Workshop on Medical Imaging and Augmented Reality, held at the Xia- shan (Fragrant Hills) Hotel, Beijing, during August 19–20, 2004. The goal of MIAR 2004 was to bring together researchers in computer vision, graphics, robotics, and medical imaging to present the state-of-the-art developments in this ever-growing research area. The meeting consisted of a single track of oral/poster presentations, with each session led by an invited lecture from our distinguished international f- ulty members. For MIAR 2004, we received 93 full submissions, which were sub- quently reviewed by up to 5 reviewers, resulting in the acceptance of the 41 full - pers included in this volume.