Dendrimer Based Nanotherapeutics

Dendrimer Based Drug Delivery Systems Book PDF
✏Book Title : Dendrimer Based Drug Delivery Systems
✏Author : Yiyun Cheng
✏Publisher : John Wiley & Sons
✏Release Date : 2012-07-03
✏Pages : 514
✏ISBN : 9780470460054
✏Available Language : English, Spanish, And French

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✏Dendrimer Based Drug Delivery Systems Book Summary : This book focuses on the formulation and delivery of dendrimers. It offers both a comprehensive introduction and reference to practical applications. The coverage encompasses dendritic drug delivery systems ranging from dendrimers chemistry to cellular uptake of dendritic nanoparticles.

Biomedical Applications Of Peptide Glyco And Glycopeptide Dendrimers And Analogous Dendrimeric Structures Book PDF
✏Book Title : Biomedical Applications of Peptide Glyco and Glycopeptide Dendrimers and Analogous Dendrimeric Structures
✏Author : Jaroslav Sebestik
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-13
✏Pages : 238
✏ISBN : 9783709112069
✏Available Language : English, Spanish, And French

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✏Biomedical Applications of Peptide Glyco and Glycopeptide Dendrimers and Analogous Dendrimeric Structures Book Summary : Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers.

The Handbook Of Nanomedicine Book PDF
✏Book Title : The Handbook of Nanomedicine
✏Author : Kewal K. Jain
✏Publisher : Humana Press
✏Release Date : 2017-03-20
✏Pages : 659
✏ISBN : 9781493969661
✏Available Language : English, Spanish, And French

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✏The Handbook of Nanomedicine Book Summary : Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.

Nanooncology An Issue Of Clinics In Laboratory Medicine E Book Book PDF
✏Book Title : NanoOncology An Issue of Clinics in Laboratory Medicine E Book
✏Author : Kewal Jain
✏Publisher : Elsevier Health Sciences
✏Release Date : 2012-03-26
✏Pages : 120
✏ISBN : 9781455742899
✏Available Language : English, Spanish, And French

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✏NanoOncology An Issue of Clinics in Laboratory Medicine E Book Book Summary : This issue of Clinics in Laboratory Medicine includes the following topics: Detection of cancer biomarkers by cerium oxide nanoparticles; Quantum dot-based assays for cancer biomarkers; Monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo diagnosis of cancer; RNA quantification with gold nanoprobes for cancer diagnostics; Nanostructured silica materials for imaging in cancer; and Nanoparticle-based cancer cell sorting.

Nanoparticulate Drug Delivery Systems Book PDF
✏Book Title : Nanoparticulate Drug Delivery Systems
✏Author : Yoon Yeo
✏Publisher : John Wiley & Sons
✏Release Date : 2013-02-25
✏Pages : 324
✏ISBN : 9781118570517
✏Available Language : English, Spanish, And French

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✏Nanoparticulate Drug Delivery Systems Book Summary : Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

Handbook Of Nanotoxicology Nanomedicine And Stem Cell Use In Toxicology Book PDF
✏Book Title : Handbook of Nanotoxicology Nanomedicine and Stem Cell Use in Toxicology
✏Author : Saura C. Sahu
✏Publisher : John Wiley & Sons
✏Release Date : 2014-04-22
✏Pages : 440
✏ISBN : 9781118855867
✏Available Language : English, Spanish, And French

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✏Handbook of Nanotoxicology Nanomedicine and Stem Cell Use in Toxicology Book Summary : The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.

Multifunctional Pharmaceutical Nanocarriers Book PDF
✏Book Title : Multifunctional Pharmaceutical Nanocarriers
✏Author : Vladimir Torchilin
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-03-21
✏Pages : 474
✏ISBN : 9780387765549
✏Available Language : English, Spanish, And French

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✏Multifunctional Pharmaceutical Nanocarriers Book Summary : The editors have brought together leading experts in multifunctional nanopharmaceuticals to provide cutting edge information; a critical overview of the field; and analysis of current and potential future developments to speed the subject’s rapid development.

Experimental Biology And Medicine Book PDF
✏Book Title : Experimental Biology and Medicine
✏Author :
✏Publisher :
✏Release Date : 2009
✏Pages :
✏ISBN : UCLA:L0098922990
✏Available Language : English, Spanish, And French

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✏Experimental Biology and Medicine Book Summary :

Pharmaceutical Applications Of Dendrimers Book PDF
✏Book Title : Pharmaceutical Applications of Dendrimers
✏Author : Hitesh Kulhari
✏Publisher : Elsevier
✏Release Date : 2019-11-15
✏Pages : 500
✏ISBN : 0128145277
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Applications of Dendrimers Book Summary : Dendrimers are engineered nano-sized macromolecule with a high degree of molecular uniformity, narrow size distribution, tunable size, multivalency and high surface functionality. These favourable characteristics make dendrimers effective drug delivery carriers. As a result, dendrimers have demonstrated wide applicability in nanopharmaceuticals Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in solubilisation of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. Dendrimers have been successfully used as a solubility enhancer and drug delivery carrier. Dendrimer-based formulations have also been used for transfection or gene delivery. Diagnostic applications of dendrimers include MRI contrast agent and imaging of diseased areas. In addition, dendrimers such as PPI and PAMAM are reported to possess anti-inflammatory, antimicrobial and antiviral activities. In past five years, photosensitizers such as rose Bengal and protoporphyrin IX have also been delivered using PAMAM and PPI dendrimers for the treatment of cancer. These important and emerging uses are discussed here in detail. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. Explores the role of dendrimers in the design of dendritic nanoplateforms for targeted drug and gene delivery systems Discusses the potential of dendrimers in preformulation and formulation development Addresses the clinical and regulatory challenges in the development of dendrimer-based formulations

📒Nanotherapeutics ✍ Alf Lamprecht

Nanotherapeutics Book PDF
✏Book Title : Nanotherapeutics
✏Author : Alf Lamprecht
✏Publisher : CRC Press
✏Release Date : 2016-04-19
✏Pages : 292
✏ISBN : 9789814241168
✏Available Language : English, Spanish, And French

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✏Nanotherapeutics Book Summary : This timely book provides an overview of possible therapeutic applications. The first part of the book highlights general properties of and phenomena observed with nanoparticles, and the subsequent consequences for applications in drug delivery. The second part focuses on the therapeutic approaches that are possible through the use of nanoparticles, with each chapter discussing a specific disease (e.g., diabetes, cancer, inflammation) and the relevant therapeutic approaches based on the design of nanoparticulate drug delivery systems. From this concise book, readers will gain an insight into the basics of nanoparticle preparation and find a more detailed account of what is therapeutically feasible by using nanoparticle approaches.

Nanotechnology Based Targeted Drug Delivery Systems For Lung Cancer Book PDF
✏Book Title : Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer
✏Author : Prashant Kesharwani
✏Publisher : Academic Press
✏Release Date : 2019-01-26
✏Pages : 340
✏ISBN : 9780128163672
✏Available Language : English, Spanish, And French

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✏Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer Book Summary : Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Dendrimers And Other Dendritic Polymers Book PDF
✏Book Title : Dendrimers and Other Dendritic Polymers
✏Author : Jean M. J. FrĂ©chet
✏Publisher : John Wiley & Sons
✏Release Date : 2001
✏Pages : 647
✏ISBN : UOM:39015054295467
✏Available Language : English, Spanish, And French

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✏Dendrimers and Other Dendritic Polymers Book Summary : With contributions from many of the world's leading scientists in the field of dendritic research and development, Dendrimers and Other Dendritic Polymers provides a comprehensive review of this rapidly expanding and exciting new field of polymer science. Of interest to academia and industry alike, this book covers the synthesis, characterization, unique properties, potential for novel applications and technical challenges associated with these polymers. * Detailed coverage of all known subclasses of dendritic polymers, including their properties and synthesis * Insight into the potential commercial applications of dendritic polymers, including drug delivery, cancer therapy, coatings and adhesives * Identification of the key trends and perspectives in dendrimer research * Essential reference for polymer chemists, materials scientists and plastics engineers working in academia and industry alike

The Textbook Of Nanoneuroscience And Nanoneurosurgery Book PDF
✏Book Title : The Textbook of Nanoneuroscience and Nanoneurosurgery
✏Author : Babak Kateb
✏Publisher : CRC Press
✏Release Date : 2013-07-25
✏Pages : 602
✏ISBN : 9781439849422
✏Available Language : English, Spanish, And French

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✏The Textbook of Nanoneuroscience and Nanoneurosurgery Book Summary : Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 10-20 years. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a state-of-the-art review of the field, providing current information about n

📒Biosensors Nanotechnology ✍ Ashutosh Tiwari

Biosensors Nanotechnology Book PDF
✏Book Title : Biosensors Nanotechnology
✏Author : Ashutosh Tiwari
✏Publisher : John Wiley & Sons
✏Release Date : 2014-06-26
✏Pages : 552
✏ISBN : 9781118773819
✏Available Language : English, Spanish, And French

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✏Biosensors Nanotechnology Book Summary : This book provides detailed reviews of a range of nanostructures used in the construction of biosensors as well as the applications of these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields Biological sensing is a fundamental tool for understanding living systems, but also finds practical application in medicine, drug discovery, process control, food safety, environmental monitoring, defense, and personal security. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation, and computing. Advances in telecommunications, expert systems, and distributed diagnostics prompt us to question the current ways we deliver healthcare, while robust industrial sensors enable new paradigms in R&D and production. Despite these advances, there is a glaring absence of suitably robust and convenient sensors for body chemistries. This book examines some of the emerging technologies that are fueling scientific discovery and underpinning new products to enhance the length and quality of our lives. The 14 chapters written by leading experts cover such topics as: ZnO and graphene microelectrode applications in biosensing Assembly of polymers/metal nanoparticles Gold nanoparticle-based electrochemical biosensors Impedimetric DNA sensing employing nanomaterials Graphene and carbon nanotube-based biosensors Computational nanochemistry study of the BFPF green fluorescent protein chromophore Biosynthesis of metal nanoparticles Bioconjugated-nanoporous gold films in electrochemical biosensors The combination of molecular imprinting and nanotechnology Principles and properties of multiferroics and ceramics

Advances In Personalized Nanotherapeutics Book PDF
✏Book Title : Advances in Personalized Nanotherapeutics
✏Author : Ajeet Kaushik
✏Publisher : Springer
✏Release Date : 2017-12-08
✏Pages : 240
✏ISBN : 9783319636337
✏Available Language : English, Spanish, And French

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✏Advances in Personalized Nanotherapeutics Book Summary : Personalized health care to manage diseases and optimized treatment is crucial for everyone to maintain health quality. Significant efforts have been made to design and develop novel nano-enabling therapeutic strategies to cure and monitor diseases for personalized health care. As state-of-the-art, various strategies have been reported to develop personalized nanomedicine to combat against target diseases with no side effects. In this book proposal, we are trying to describe fundamentals of personalized nanomedicine, novel nanomaterials for drug delivery, role of nanotechnology for efficient therapeutics approach, nano-pharmacology, targeted CNS drug delivery, stimuli responsive drug release and nanotechnology for diseases management. This book would serve as a platform for new scholars to understand state-of-the-art of nanotechnology for therapeutics and designing their future research to develop effective personalized nanomedicine against targeted diseases. As of now, various studies have been reported to design and develop nanomedicines of higher efficacy but unfortunately, such products are up to laboratory research only and need to be well-tested using pre-clinical or human models. Our book would be a call for experts to explore multidisciplinary research for developing novel and efficient approaches to explore smart efficient nanocarriers for site-specific on-demand controlled drug delivery to combat against targeted diseases to personalized health care.

Handbook Of Harnessing Biomaterials In Nanomedicine Book PDF
✏Book Title : Handbook of Harnessing Biomaterials in Nanomedicine
✏Author : Dan Peer
✏Publisher : CRC Press
✏Release Date : 2012-01-12
✏Pages : 424
✏ISBN : 9789814364270
✏Available Language : English, Spanish, And French

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✏Handbook of Harnessing Biomaterials in Nanomedicine Book Summary : This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Nanoparticles In Translational Science And Medicine Book PDF
✏Book Title : Nanoparticles in Translational Science and Medicine
✏Author :
✏Publisher : Academic Press
✏Release Date : 2011-11-14
✏Pages : 648
✏ISBN : 9780123914637
✏Available Language : English, Spanish, And French

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✏Nanoparticles in Translational Science and Medicine Book Summary : This volume explores some of the most exciting recent advances in basic research on nanoparticles in translational science and medicine and how this knowledge is leading to advances in the various fields. This series provides a forum for discussion of new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

Nanopharmaceuticals Principles And Applications Vol 2 Book PDF
✏Book Title : Nanopharmaceuticals Principles and Applications Vol 2
✏Author : Vinod Kumar Yata
✏Publisher : Springer Nature
✏Release Date : 2020-07-14
✏Pages : 366
✏ISBN : 9783030449216
✏Available Language : English, Spanish, And French

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✏Nanopharmaceuticals Principles and Applications Vol 2 Book Summary : This book presents the comprehensive description of basic principles, methodologies, similarities and differences of nano-liposomes and -phytosomes. It focuses on the implications of these nano carriers in drug delivery and also includes detailed classification of nanoinonized drug particles, polymeric nanoparticles and hydrophobic nanoparticles. This book concludes with the biological, technical and study-design challenges of Nanopharmaceuticals and presents critical viewpoints of smart DNA nanostructures. The risk factors and regulatory concerns have also been kept in focus and the book includes the toxicity and application of different types of ionic liquids for humans and environment. It also critically describes characteristics, applications and regulatory gaps of nanoparticle-ionic liquid combined systems.

Nanotechnology And Nanomaterials In The Treatment Of Life Threatening Diseases Book PDF
✏Book Title : Nanotechnology and Nanomaterials in the Treatment of Life threatening Diseases
✏Author : Narenda Kumar
✏Publisher : William Andrew
✏Release Date : 2013-12-05
✏Pages : 408
✏ISBN : 9780323264501
✏Available Language : English, Spanish, And French

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✏Nanotechnology and Nanomaterials in the Treatment of Life threatening Diseases Book Summary : Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases takes a scientific approach to nanotechnology and nanomaterials applications in medicine, while also explaining the core biological principles for an audience of biomedical engineers, materials scientists, pharmacologists, and medical diagnostic technicians. The book is structured by major disease groups, offering a practical, application-based focus for scientists, engineers, and clinicians alike. The spectrum of medical applications is explored, from diagnostics and imaging to drug delivery, monitoring, therapies, and disease prevention. It also focuses specifically on the synthesis of nanomaterials and their potential health risks (particularly toxicity). Nanomedicine — the application of nanomaterials and devices for addressing medical problems — has demonstrated great potential for enabling improved diagnosis, treatment, and monitoring of many serious illnesses, including cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory and infectious diseases. Gain an understanding of how nanotechnologies and nanomaterials can be deployed in the fight against the major life-threatening diseases: cancer, neurological disorders (including Alzheimer's and Parkinson's), cardiovascular diseases, and HIV/AIDS Discover the latest developments in nanomedicine, from therapies and drug delivery to diagnostics and disease prevention The authors cover the health risks of nanomaterials as well as their benefits, considering toxicity and potential carcinogens

Nanopharmaceuticals Principles And Applications Vol 3 Book PDF
✏Book Title : Nanopharmaceuticals Principles and Applications Vol 3
✏Author : Vinod Kumar Yata
✏Publisher : Springer Nature
✏Release Date :
✏Pages :
✏ISBN : 9783030471200
✏Available Language : English, Spanish, And French

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✏Nanopharmaceuticals Principles and Applications Vol 3 Book Summary :

Genetic Engineering News Book PDF
✏Book Title : Genetic Engineering News
✏Author :
✏Publisher :
✏Release Date : 2005
✏Pages :
✏ISBN : STANFORD:36105121616309
✏Available Language : English, Spanish, And French

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✏Genetic Engineering News Book Summary :

Nanomaterials And Nanosystems For Biomedical Applications Book PDF
✏Book Title : Nanomaterials and Nanosystems for Biomedical Applications
✏Author : M. Reza Mozafari
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-09-19
✏Pages : 162
✏ISBN : 9781402062896
✏Available Language : English, Spanish, And French

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✏Nanomaterials and Nanosystems for Biomedical Applications Book Summary : Under a single cover, this book brings together various aspects of functional bioengineered materials and nanostructured biomaterials including commonly used implants and sustained release nanodevices. The book includes expert reviews on the advances and current problems associated with the implants and nanodevices. Containing recent citations and bibliographies, this book will be an indispensable source of information for new researchers and scientists.

Particulate Technology For Delivery Of Therapeutics Book PDF
✏Book Title : Particulate Technology for Delivery of Therapeutics
✏Author : Sougata Jana
✏Publisher : Springer
✏Release Date : 2017-10-09
✏Pages : 451
✏ISBN : 9789811036477
✏Available Language : English, Spanish, And French

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✏Particulate Technology for Delivery of Therapeutics Book Summary : The book focuses on novel particulate technologies for the purpose of drug delivery to humans. Nowadays, macro and nano-scale particles are being investigated for targeted delivery of small and large biological macromolecules. The targeting of drugs can minimize the dosage regimen and reduces dose related potential toxicity of drug molecules, which in turn lead to increased potential compliance. Various types of organic, inorganic and polymer particles are currently being investigated. These are attracting the attention of the research workers in the field of drug delivery science and technology. This book covers polymersomes, inorganic- organic composites, gold nanoparticles biopolymer and synthetic polymer particles etc.All aspects of drug delivery in relation to each technology have been described including these advances, Easy to read and understand the content of each chapter Rich in up-to-date information regarding their application.

Design And Synthesis Of Nanoparticle Paint Brush Like Multi Hydroxyl Capped Poly Ethylene Glycol Conjugates For Cancer Nanotherapy Book PDF
✏Book Title : Design and Synthesis of Nanoparticle PAINT BRUSH Like Multi hydroxyl Capped Poly ethylene Glycol Conjugates for Cancer Nanotherapy
✏Author : Vinu Krishnan
✏Publisher :
✏Release Date : 2008
✏Pages : 130
✏ISBN : OCLC:476464329
✏Available Language : English, Spanish, And French

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✏Design and Synthesis of Nanoparticle PAINT BRUSH Like Multi hydroxyl Capped Poly ethylene Glycol Conjugates for Cancer Nanotherapy Book Summary : "Statistical figures outline the five-year survival rate for all cancers diagnosed between 1996 and 2002 as 66%, which depicts a marked rise from the 51% that survived in 1975-1977 (1). However, cancer still remains the second leading cause of death in the United States, following heart disease. An American Cancer Society report estimated that in 2007, there will be over 1.4 million new cancer cases and over half a million cancer deaths in the United States (1). Although significant oncology drug discoveries have been made during the past 30 years, conventional chemotherapeutic agents exhibit poor specificity in reaching the tumor site and are often restricted by toxicity factors. The lack of a uniform biodistribution leads to harmful side-effects to healthy tissues and the need for administration of a larger than necessary drug dosage with a higher repetitive rate so as to elicit a satisfactory pharmacological response. Wide interest in cancer nanotherapy has led to the development of nanoparticle based "smart drugs" that have not only improved pharmacological and therapeutic properties of anticancer drugs, but also offer a less invasive alternative enhancing the patient's life expectancy and quality of life as well. Dendrimers, due to their unique architecture and macromolecular characteristics are currently used extensively in research of nanoparticles for targeted and controlled drug delivery. The research objective was to design, synthesize and characterize a novel nanoparticle based "PAINT-BRUSH" like multi-hydroxyl capped poly (ethylene glycol) (PEG) conjugate using the dendron - bishomotris that may have a potential use in targeted cancer nanotherapy. Characterization of the conjugates suggested that the synthesis was successful; resulting in the formation of nanoparticle "PAINT-BRUSH" conjugates. It was also found that these conjugates remain stable under normal physiological conditions but would activate in response to an acidic pH (a characteristic trait of target cancer cells) so as to release the anticancer drug. The research also presents the relative cell viability of the human epithelial carcinoma cell line (HeLa S3) with respect to in-vitro characterization of the conjugate to determine its suitability as a drug delivery vector. The study demonstrated that bishomotris was cytotoxic in nature evidently due to the interaction of positively charged amine group with the surface of HeLa cells. It was also evident that surface modification by PEGylation has led to a distinct reduction in toxicity levels thus laying foundations for further research to realize a promising new scaffold for cancer nanotherapy."--Abstract.

📒Nanocarrier Technologies ✍ M. Reza Mozafari

Nanocarrier Technologies Book PDF
✏Book Title : Nanocarrier Technologies
✏Author : M. Reza Mozafari
✏Publisher : Springer Science & Business Media
✏Release Date : 2006-09-24
✏Pages : 226
✏ISBN : 9781402050411
✏Available Language : English, Spanish, And French

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✏Nanocarrier Technologies Book Summary : Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies. It is the first book with this topic. It comprises a collection of scientific articles from top research people in the field and provides an up-to-date source containing recent citation and bibliography. The book is an indispensable source of information for new researchers and scientists.

Multifunctional Nanocarriers For Contemporary Healthcare Applications Book PDF
✏Book Title : Multifunctional Nanocarriers for Contemporary Healthcare Applications
✏Author : Barkat, Md. Abul
✏Publisher : IGI Global
✏Release Date : 2018-01-12
✏Pages : 602
✏ISBN : 9781522547822
✏Available Language : English, Spanish, And French

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✏Multifunctional Nanocarriers for Contemporary Healthcare Applications Book Summary : Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.

📒Smart Drug Delivery System ✍ Ali Demir Sezer

Smart Drug Delivery System Book PDF
✏Book Title : Smart Drug Delivery System
✏Author : Ali Demir Sezer
✏Publisher : BoD – Books on Demand
✏Release Date : 2016-02-10
✏Pages : 398
✏ISBN : 9789535122470
✏Available Language : English, Spanish, And French

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✏Smart Drug Delivery System Book Summary : This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

📒Nanomaterials For Cancer Therapy ✍ Challa S. S. R. Kumar

Nanomaterials For Cancer Therapy Book PDF
✏Book Title : Nanomaterials for Cancer Therapy
✏Author : Challa S. S. R. Kumar
✏Publisher : Wiley-VCH
✏Release Date : 2006-07-24
✏Pages : 413
✏ISBN : UOM:39015064903340
✏Available Language : English, Spanish, And French

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✏Nanomaterials for Cancer Therapy Book Summary : This first comprehensive overview on nanotechnological approaches to cancer therapy brings together therapeutic oncology and nanotechnology, showing the various strategic approaches to selectively eliminating cancerous cells without damaging the surrounding healthy tissue. The strategies covered include magnetic, optical, microwave and neutron absorption techniques, nanocapsules for active agents, nanoparticles as active agents, and active and passive targeting, while also dealing with fundamental aspects of how nanoparticles cross biological barriers. A valuable single source gathering the many articles published in specialized journals often difficult to locate for members of the other disciplines involved.

Nanopharmaceutical Advanced Delivery Systems Book PDF
✏Book Title : Nanopharmaceutical Advanced Delivery Systems
✏Author : Vivek Dave
✏Publisher : Wiley-Scrivener
✏Release Date : 2021-02-03
✏Pages : 502
✏ISBN : 1119711665
✏Available Language : English, Spanish, And French

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✏Nanopharmaceutical Advanced Delivery Systems Book Summary : The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

📒Nanopharmaceutics ✍ Xing-Jie Liang

Nanopharmaceutics Book PDF
✏Book Title : Nanopharmaceutics
✏Author : Xing-Jie Liang
✏Publisher : World Scientific
✏Release Date : 2013
✏Pages : 594
✏ISBN : 9789814368667
✏Available Language : English, Spanish, And French

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✏Nanopharmaceutics Book Summary : Nanomaterials, with their unique size-dependent physical and chemical properties, have shown promising advantages as drug and gene delivery vehicles, ultra-sensitive intracellular detectors and novel therapeutic drugs. Nanopharmaceutics is one of the disciplines that will benefit the most from this technology. Nanotechnology will have a revolutionary impact on cancer diagnosis and therapy due to the exceptional characteristics of nanopharmaceutics. This book provides an overview of some tools, methods, and materials of nanotechnology that offer potential applications in pharmaceutics, followed by a series of examples showing applications that are already in development. It may very well inspire researchers to develop a new generation of pharmaceutics with inventive non-traditional approach and employ nanoscale science for the benefit of the patient.