Clinical Pharmacology of Anti Epileptic Drugs

• Author : H. Schneider,D. Janz,C. Gardner - Thorpe,H. Meinardi,A. L. Sherwin
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

"He who is faithfully analysing ... epi lepsy is doing far more than studying epilepsy" Hughlings Jackson Modifying this well-known statement by Jackson, one could say today: "He who is faithfully analysing anti-epileptic drugs is doing far more than studying anti-epileptic drugs". For these drugs not only serve to prevent epileptic fits and thus advance the treatment of epilepsy, they are also effective in the treatment of cardiac arrhythmias and trigeminal neuralgia. Furthermore, clinical pharmacologists consider anti-epi leptic drugs as model

• Author : Ali A. Asadi-Pooya,Michael R. Sperling
• Publisher : Oxford University Press
• Release : 25 March 2023

This concise handbook provides practical, up-to-date clinical guidance on effective selection, prescription, and usage of antiepileptic drugs for patients with epilepsy in various medical conditions and in a variety of clinical contexts. This text discusses choosing drugs when faced with various medical comorbidities; how to correctly prescribe, titrate, and taper drugs; how to monitor drug efficacy and side effects; how to diagnose and manage toxicity; how antiepileptic drugs interact with other medications; and comprehensive coverage of current treatment options. Key

• Author : Philip N. Patsalos,Erik K. St Louis
• Publisher : Unknown
• Release : 14 June 2018

This concise book is the essential clinical reference guide for practitioners who care for patients with epilepsy throughout their lifespan.

• Author : Hans-Hasso Frey,D. Janz
• Publisher : Springer
• Release : 16 January 2012

Epileptic disorders need treatment for many years or even for life, and this makes a thorough understanding of the pharmacokinetics and possible hazards and side effects of the drugs used in treatment mandatory. During recent decades our knowledge in this field has considerably increased, not least as a result of the development of specific and sensitive methods for the determination of anti epileptic agents in biological material. The clinical pharmacology of this group of drugs has been studied extensively and

• Author : M.J. Eadie,F. Vajda
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

In 1985, volume 74 of the Springer-Verlag Handbook of Experimental Phar macology, under the editorship of H. -H. Frey and D. Janz, appeared. In this volume the then available data on the topic of antiepileptic drugs were col lated and analysed. Over the intervening years knowledge in this area has grown progressively. More new antiepileptic drugs than the total number of agents that were in common use 15 years ago have in the interval either come on to the market or are about

• Author : Mervyn J. Eadie,John H. Tyrer
• Publisher : Unknown
• Release : 25 March 1989

• Author : L. Beani,Dieter Janz
• Publisher : Springer
• Release : 25 March 1985

• Author : Philip N. Patsalos,Blaise F. D. Bourgeois
• Publisher : Cambridge University Press
• Release : 01 July 2010

The Epilepsy Prescriber's Guide to Antiepileptic Drugs provides a practical and concise reference guide for use by all those clinicians and allied health professionals that treat or care for patients with epilepsy. In full colour throughout, this volume presents the antiepileptic drugs (AEDs) in alphabetical order and for each AED the information is divided into eight coloured sections: general therapeutics, pharmacokinetics, interaction profile, adverse effects, dosing and use, special populations, and suggested reading. This handy pocket guide will be an

• Author : Philip N. Patsalos
• Publisher : Springer
• Release : 26 July 2016

This updated third edition of a successful book is a description of both pharmacokinetic and pharmacodynamic antiepileptic drug (AED) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be coprescribed without undue concern. Presented in alphabetical order and by drug class, drug interactions that occur between AEDs and also between AEDs and non-AEDs are described in three sections: Drug interactions between AEDs; Drug interactions between

• Author : Philip Patsalos
• Publisher : Springer Science & Business Media
• Release : 03 December 2012

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make

• Author : Philip N. Patsalos
• Publisher : Cambridge University Press
• Release : 21 November 2013

This practical and concise book is an essential reference guide for use by all clinicians and allied health professionals that treat or care for patients with epilepsy. In full color throughout, this volume presents the antiepileptic drugs (AEDs), 34 in total, in alphabetical order and for each AED the information is divided into eight colored sections: general therapeutics, pharmacokinetics, interaction profile, adverse effects, dosing and use, special populations, overview, and suggested reading. This second edition has been extensively revised and updated.

• Author : Hannsjörg W. Seyberth,Anders Rane,Matthias Schwab
• Publisher : Springer Science & Business Media
• Release : 01 September 2011

The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.

• Author : Katrina L. Mealey
• Publisher : Elsevier Health Sciences
• Release : 05 August 2013

A complete update on clinical pharmacology and therapeutics for the small animal practitioner! Topics will include regulatory aspects, pharmacokinetics and clinical practice, idiosyncratic drug toxicity, adverse drug interactions, feline deficiencies, antimicrobials, antibiotic treatment of resistant infections, outpatient analgesics, nutraceuticals, seizure management, immunosuppressive therapy, and much more!

• Author : Wolfgang Löscher
• Publisher : Birkhäuser
• Release : 06 December 2012

Since the fortuitous discovery of its anticonvulsant activIty in 1962, valproate has established itself worldwide as a major antiepileptic drug against several types of epileptic seizures. Clinical experience with valpro ate has continued to grow in recent years, including use of valproate for diseases other than epilepsy, for example in bipolar disorders and migraine. In this volume on valproate emphasis is placed on the scientific back ground leading to the discovery of val pro ate, its subsequent pharmacologi cal and toxicological

• Author : John E. Murphy
• Publisher : ASHP
• Release : 01 October 2011

In the complex field of pharmacokinetics, one reference guide has an identity all its own: Clinical Pharmacokinetics. Now the fully updated 5th edition brings to experienced practitioners and students alike the fresh information they need most: · Content organized for fast reference to specific drugs · The latest on dosing in obese and overweight patients · Dosing considerations for neonatal, pediatric and geriatric patients · A look at protein binding and its implications · Population values for a variety of drugs to initiate dosing · Drug