Clinical and Translational Science

• Author : David Robertson,Gordon H. Williams
• Publisher : Academic Press
• Release : 02 March 2009

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. Clinical and Translational Science is designed as the most authoritative and modern resource for the broad range

• Author : Debra Lerner,Marisha E. Palm,Thomas W. Concannon
• Publisher : Springer Nature
• Release : 27 February 2022

Despite the large U.S. investment in health science, and the vast and growing body of peer-reviewed research findings it has produced, a compelling body of evidence suggests that research too often has been slow, inefficient, and fallen short of desired impacts on health. A key question is how research might be changed to be more innovative, less wasteful, and more responsive to unmet health needs. One emerging response within clinical and translational science is to advance an approach that

• Author : Barbara Alving,Kerong Dai,Samuel H. H. Chan
• Publisher : Karger Medical and Scientific Publishers
• Release : 01 December 2012

This book is the first to provide an aerial view, as well as detailed information, on 'how' activities in translational medicine are under development in countries such as the USA, China, the UK, and Taiwan. Institutions in each country are training investigators to work as sophisticated interdisciplinary teams. Investigators from 11 US academic health centers explain how they are incentivizing collaborations through pilot project programs, forming partnerships with business schools to promote efficient management of basic and clinical research, creating ethical,

• Author : David Robertson,Gordon H. Williams
• Publisher : Academic Press
• Release : 01 January 2009

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and modern resource for the broad range of investigators

• Author : Arkalgud Ramaprasad,Annette L. Valenta,Ian Brooks
• Publisher : Unknown
• Release : 07 June 2023

Clinical and Translational Science (CTS) is a new and emerging academic discipline which seeks to reduce (a) the time-to-application of research to, and (b) the time-to-research of, health care problems. Translating information within and between the research and practice silos is central to CTS. The role of CTS Informatics (CTSI) can be stated as 'translating information to transform health care'. We present an ontological analysis of the transformation of health care by CTSI. The five dimensions of the ontology are

• Author : James Mittra,Christopher-Paul Milne
• Publisher : CRC Press
• Release : 17 April 2013

This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has for public health policy and commercial innovation, the book addresses the major systemic aspects of the field. The contributors explore the dynamic interactions and key challenges in translating new science

• Author : Dennis V. Cokkinos
• Publisher : Springer
• Release : 06 November 2014

The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important

• Author : Institute for Clinical and Translational Science
• Publisher : Unknown
• Release : 07 June 2023

• Author : Rakesh Srivastava,Wojciech Maksymowicz,Wlodek Lopaczynski
• Publisher : World Scientific
• Release : 14 March 2014

This book is all about the definition and finding ways to prioritize and accelerate translation research in biomedical sciences and rapidly turning new knowledge into first-in-human studies. It represents an effort to bring together scientists active in various areas of translational research to share science and, hopefully, generate new ideas and potential collaborations. The book provides a comprehensive overview of translational work that includes significant discoveries and pioneering contributions, e.g., in immunology, gene therapy, stem cells and population sciences.

• Author : Francesco Chiappelli
• Publisher : Unknown
• Release : 30 April 2014

• Author : Colleen G. Le Prell,Edward Lobarinas,Arthur N. Popper,Richard R. Fay
• Publisher : Springer
• Release : 26 October 2016

Translational Research is the interface between basic science and human clinical application, including the entire process from animal studies to human clinical trials (phases I, II, and III). Translational Research moves promising basic science results from the laboratory to bedside application. Yet, this transition is often the least-defined, least-understood part of the research process. Most scientific training programs provide little or no systematic introduction to the issues, challenges, and obstacles that prevent effective research translation, even though these are the

• Author : R.C. Sobti,Awtar Krishan Ganju
• Publisher : Springer Nature
• Release : 16 July 2022

The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel

• Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
• Publisher : Unknown
• Release : 07 June 2023

• Author : Adam E.M. Eltorai,Tao Liu,Rajat Chand,Sanjeeva P. Kalva
• Publisher : Elsevier
• Release : 14 April 2023

Translational Interventional Radiology, a volume in the Handbook for Designing and Conducting Clinical and Translational Research series, covers the principles of evidence-based medicine and applies these principles to the design of translational investigations in Interventional Radiology. The reader will come to fully understand important concepts including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in Interventional Radiology, and

• Author : Anna Garner
• Publisher : Unknown
• Release : 12 June 2019

Clinical and translational medicine refers to the therapeutic clinical potential and application of translational research that seeks to develop the understanding of mechanisms and treatments of human diseases. The clinical variation between diseases, biomarkers, pathogenesis and therapies are also highlighted through studies of clinical and translational medicine. This is a critical and core component of the full-spectrum of biomedical research. Translational medicine refers to an area of research that seeks to determine the relevance of novel discoveries in the biological