Chemical Sciences in Early Drug Discovery

Produk Detail:
  • Author : Pierfausto Seneci
  • Publisher : Elsevier
  • Pages : 194 pages
  • ISBN : 008099928X
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Chemical Sciences in Early Drug Discovery

Download or Read online Chemical Sciences in Early Drug Discovery full in PDF, ePub and kindle. this book written by Pierfausto Seneci and published by Elsevier which was released on 05 June 2018 with total page 194 pages. We cannot guarantee that Chemical Sciences in Early Drug Discovery book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery. Reviews the key application of chemistry in drug discovery for both medicinal and non-medicinal chemists, clarifying and explaining the role of medicinal chemistry in supporting the modern drug discovery pipeline Shows how a wider medicinal chemistry view is essential for anyone in an integrated drug discovery project looking to reduce costs and save time Provides the critical success factors needed to successfully identify hits from both biological and chemical perspectives

Chemical Sciences in Early Drug Discovery

Chemical Sciences in Early Drug Discovery
  • Author : Pierfausto Seneci
  • Publisher : Elsevier
  • Release : 05 June 2018
GET THIS BOOK Chemical Sciences in Early Drug Discovery

Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the

Pharmaceutical Process Development

Pharmaceutical Process Development
  • Author : A. John Blacker,Mike T. Williams
  • Publisher : Royal Society of Chemistry
  • Release : 23 October 2021
GET THIS BOOK Pharmaceutical Process Development

This book is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry by informing them about the breadth of the work carried out in chemical research and development departments. It is also of great value to academics wishing to advise students on the merits of careers in chemical development over discovery.

Small Molecule Drug Discovery

Small Molecule Drug Discovery
  • Author : Andrea Trabocchi,Elena Lenci
  • Publisher : Elsevier
  • Release : 04 December 2019
GET THIS BOOK Small Molecule Drug Discovery

Small Molecule Drug Discovery: Methods, Molecules and Applications presents the methods used to identify bioactive small molecules, synthetic strategies and techniques to produce novel chemical entities and small molecule libraries, chemoinformatics to characterize and enumerate chemical libraries, and screening methods, including biophysical techniques, virtual screening and phenotypic screening. The second part of the book gives an overview of privileged cyclic small molecules and major classes of natural product-derived small molecules, including carbohydrate-derived compounds, peptides and peptidomimetics, and alkaloid-inspired compounds. The

Early Drug Development

Early Drug Development
  • Author : Fabrizio Giordanetto
  • Publisher : John Wiley & Sons
  • Release : 11 June 2018
GET THIS BOOK Early Drug Development

This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the

Lead Generation Approaches in Drug Discovery

Lead Generation Approaches in Drug Discovery
  • Author : Zoran Rankovic,Richard Morphy
  • Publisher : John Wiley & Sons
  • Release : 07 April 2010
GET THIS BOOK Lead Generation Approaches in Drug Discovery

An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory,

New Drug Discovery and Development

New Drug Discovery and Development
  • Author : Daniel Lednicer
  • Publisher : John Wiley & Sons
  • Release : 20 October 2006
GET THIS BOOK New Drug Discovery and Development

A case history approach to drug synthesis and discovery Discover the origins of some of today’s most popular drug therapies. Explore case histories and gain insight into major classes of antibiotics, antiviral drugs, analgesics, steroids, compounds designed to lower cholesterol, and more. Review the steps required for FDA approval. This is a great reference for students in medicinal chemistry, researchers in pharmaceuticals, and medical practitioners.

High Throughput Analysis for Early Drug Discovery

High Throughput Analysis for Early Drug Discovery
  • Author : James Kyranos
  • Publisher : Elsevier
  • Release : 18 September 2004
GET THIS BOOK High Throughput Analysis for Early Drug Discovery

High Throughput Analysis for Early Drug Discovery offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each chapter or section begins with a description of the synthesis approach and its advantages. The description of various combinatorial and high-throughput parallel synthesis techniques provide a relevant point of entry for synthetic

Health and Medicine

Health and Medicine
  • Author : National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Challenges for the Chemical Sciences in the 21st Century,Organizing Committee for the Workshop on Health and Medicine
  • Publisher : National Academies Press
  • Release : 02 March 2004
GET THIS BOOK Health and Medicine

The report assesses the current state of chemistry and chemical engineering within the context of drug discovery, disease diagnosis, and disease prevention. Also addressed are chemical and chemical engineering challenges in pharmaceutical synthesis, delivery, and manufacture.

Machine Learning in Chemistry

Machine Learning in Chemistry
  • Author : Jon Paul Janet,Heather J. Kulik
  • Publisher : American Chemical Society
  • Release : 28 May 2020
GET THIS BOOK Machine Learning in Chemistry

Recent advances in machine learning or artificial intelligence for vision and natural language processing that have enabled the development of new technologies such as personal assistants or self-driving cars have brought machine learning and artificial intelligence to the forefront of popular culture. The accumulation of these algorithmic advances along with the increasing availability of large data sets and readily available high performance computing has played an important role in bringing machine learning applications to such a wide range of disciplines.

Comprehensive Medicinal Chemistry III

Comprehensive Medicinal Chemistry III
  • Author : Simon Ward
  • Publisher : Academic Press
  • Release : 01 July 2017
GET THIS BOOK Comprehensive Medicinal Chemistry III

Comprehensive Medicinal Chemistry III, Third Edition provides a contemporary and forward looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of

Fundamentals of Early Clinical Drug Development

Fundamentals of Early Clinical Drug Development
  • Author : Ahmed F. Abdel-Magid,Stéphane Caron
  • Publisher : John Wiley & Sons
  • Release : 29 September 2006
GET THIS BOOK Fundamentals of Early Clinical Drug Development

An informative look at the intricacies of today's drug development process Once a discovery organization has identified a potential new drug candidate, it is the daunting task of synthetic organic chemists to identify the chemical process suitable for preparation of this compound in a highly regulated environment. Only through a multi-layered chemical process that takes into account such factors as safety, environmental considerations, freedom to operate and cost-effectiveness can researchers begin to refine the drug in terms of quality and

Challenges in Chemistry Graduate Education

Challenges in Chemistry Graduate Education
  • Author : National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Challenges in Chemistry Graduate Education; Board on Chemical Sciences
  • Publisher : National Academies Press
  • Release : 21 August 2012
GET THIS BOOK Challenges in Chemistry Graduate Education

Chemistry graduate education is under considerable pressure. Pharmaceutical companies, long a major employer of synthetic organic chemists, are drastically paring back their research divisions to reduce costs. Chemical companies are opening new research and development facilities in Asia rather than in the United States to take advantage of growing markets and trained workforces there. Universities, especially public universities, are under significant fiscal constraints that threaten their ability to hire new faculty members. Future federal funding of chemical research may be

Medicinal Chemistry for Practitioners

Medicinal Chemistry for Practitioners
  • Author : Jie Jack Li
  • Publisher : John Wiley & Sons
  • Release : 16 June 2020
GET THIS BOOK Medicinal Chemistry for Practitioners

Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.

Chemogenomics in Drug Discovery

Chemogenomics in Drug Discovery
  • Author : Hugo Kubinyi,Gerhard Müller
  • Publisher : Wiley-VCH
  • Release : 06 March 2006
GET THIS BOOK Chemogenomics in Drug Discovery

Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics. This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design. With the combined expertise of 20 research groups from academia and leading pharmaceutical companies, this is a must-have for every drug developer and medicinal chemist applying the powerful methods of chemogenomics to speed up the drug discovery