Capillary Electrophoresis Methods For Pharmaceutical Analysis

Capillary Electrophoresis Methods For Pharmaceutical Analysis Book PDF
✏Book Title : Capillary Electrophoresis Methods for Pharmaceutical Analysis
✏Author : Satinder Ahuja
✏Publisher : Elsevier
✏Release Date : 2011-08-09
✏Pages : 546
✏ISBN : 9780080559612
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Methods for Pharmaceutical Analysis Book Summary : Capillary electrophoresis (CE) is a powerful analytical technique that is widely used in research and development and in quality control of pharmaceuticals. Many reports of highly efficient separations and methods have been published over the past 15 years. CE offers several advantages over high-pressure or high-performance liquid chromatography (HPLC). These include simplicity, rapid analysis, automation, ruggedness, different mechanisms for selectivity, and low cost. Moreover, EC requires smaller sample size and yet offers higher efficiency and thus greater resolution power over HPLC. These characteristics are very attractive in research and development, even more so in pharmaceutical quality control (QC) and stability monitoring (SM) studies. This book will provide busy pharmaceutical scientists a complete yet concise reference guide for utilizing the versatility of CE in new drug development and quality control. - Provides current status and future developments in CE analysis of pharmaceuticals. - Explains how to develop and validate methods. - Includes major pharmaceutical applications including assays and impurity testing.

Capillary Electrophoresis Methods For Pharmaceutical Analysis Book PDF
✏Book Title : Capillary Electrophoresis Methods for Pharmaceutical Analysis
✏Author : George Lunn
✏Publisher : Wiley-Interscience
✏Release Date : 2000-02-21
✏Pages : 1544
✏ISBN : UOM:39015050045668
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Methods for Pharmaceutical Analysis Book Summary : Capillary Electrophoresis Techniques for Pharmaceutical Analysis at your fingertips-A complete, up-to-date library. This invaluable database--also available on CD-ROM--gives you fast, easy access to the growing literature on capillary electrophoresis (CE). Nearly 3,000 abstracts from approximately 900 publications make up this comprehensive library, listing CE techniques for the analysis of more than 700 active pharmaceutical compounds. From acarbose to mephobarbital to zopiclone--a number of procedures are grouped together for each compound. Detailed, precise information lets you replicate methods without referring to original articles as well as customize methods for specific needs. Features include: * Methods for drugs in biological fluids such as blood or urine as well as for bulk and formulated drugs * Name and structure of each target compound as well as molecular weight and formula, CAS registry numbers, and Merck index number * Experimental conditions for each method, including sample preparation, analytical matrix, capillary/capillary instrument model, capillary temperature, interfering compounds, and more * Bibliography of reviews of capillary electrophoresis procedures The CD-ROM additionally combines the four-volume HPLC Methods for Pharmaceutical Analysis with thousands of methods listed for more than 1,300 compounds. This immensely useful reference will save you countless hours of online and library research.

Capillary Electrophoresis Methods For Pharmaceutical Analysis Book PDF
✏Book Title : Capillary Electrophoresis Methods For Pharmaceutical Analysis
✏Author : Ahuja
✏Publisher :
✏Release Date : 2009-01-01
✏Pages : 529
✏ISBN : 8131219410
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Methods For Pharmaceutical Analysis Book Summary :

📒Capillary Electrophoresis ✍ Philippe Schmitt-Kopplin

Capillary Electrophoresis Book PDF
✏Book Title : Capillary Electrophoresis
✏Author : Philippe Schmitt-Kopplin
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-02-25
✏Pages : 814
✏ISBN : 9781588295392
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Book Summary : This book presents a selection of current capillary electrophoresis methods used to separate representative types of molecules and particles and in combination with different detection techniques. It includes practical details which are hard to find elsewhere. The volume is intended for beginners in the field and provides an overview of the technique and a starting point for the exploration of the defined literature on different application topics.

Capillary Electrophoresis For Food Analysis Book PDF
✏Book Title : Capillary Electrophoresis for Food Analysis
✏Author : Richard A Frazier
✏Publisher : Royal Society of Chemistry
✏Release Date : 2007-10-31
✏Pages : 142
✏ISBN : 9781847550316
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis for Food Analysis Book Summary : Since its inception in the early 1980s, capillary electrophoresis (CE) offers a great deal of flexibility as a modern analytical technique, and has found applications within many fields of analysis, particularly pharmaceutical science and biochemistry. Until now, food analysts have had difficulties in adopting the technique due to the lack of written guidance. Capillary Electrophoresis for Food Analysis: Method Development provides basic information and the support needed to enable food analysts to utilise the technique for the development of new separation methods. Designed specifically for the needs of food analysts, the book takes the reader step by step through the process of developing and troubleshooting CE methods. Worked examples are included to make it ideal as a laboratory companion as well as a library reference source.

Hplc Methods For Pharmaceutical Analysis Book PDF
✏Book Title : HPLC Methods for Pharmaceutical Analysis
✏Author : George Lunn
✏Publisher : Wiley-Interscience
✏Release Date : 1997
✏Pages : 2327
✏ISBN : STANFORD:36105111547712
✏Available Language : English, Spanish, And French

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✏HPLC Methods for Pharmaceutical Analysis Book Summary : Full text included in Knovel Library within the subject area of Chemistry and Chemical Engineering.

📒Capillary Electrophoresis ✍ Suvardhan Kanchi

Capillary Electrophoresis Book PDF
✏Book Title : Capillary Electrophoresis
✏Author : Suvardhan Kanchi
✏Publisher : CRC Press
✏Release Date : 2017-08-21
✏Pages : 396
✏ISBN : 9781351846721
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Book Summary : Capillary electrophoresis (CE) has become an established method with widespread recognition as an analytical technique of choice in numerous analytical laboratories, including industrial and academic sectors. Pharmaceutical and biochemical research and quality control are the most important CE applications. This book provides a comparative assessment of related techniques on mode selection, method development, detection, and quantitative analysis and estimation of pharmacokinetic parameters and broadens the understanding of modern CE applications, developments, and prospects. It introduces the fundamentals of CE and clearly outlines the procedures used to mitigate several barriers, such as detection limits, signal detection, changing capillary environment, resolution separation of analytes, and hyphenation of mass spectrometry with CE, for a range of analytical problems. Each chapter outlines a specific electrophoretic variant with detailed instructions and some standard operating procedures. In this respect, the book meets its desired goal of rendering assistance to lovers of electrophoresis.

Pharmaceutical Analysis E Book Book PDF
✏Book Title : Pharmaceutical Analysis E Book
✏Author : David G. Watson
✏Publisher : Elsevier Health Sciences
✏Release Date : 2012-07-15
✏Pages : 406
✏ISBN : 9780702051296
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Analysis E Book Book Summary : An introductory text, written with the needs of the student in mind, which explains all the most important techniques used in the analysis of pharmaceuticals - a key procedure in ensuring the quality of drugs . The text is enhanced throughout with keypoints and self-assessment boxes, to aid student learning. Features Includes worked calculations to demonstrate mathematics in use for pharmaceutical analysis. Focuses on key points rather than a large number of facts to help readers really understand the field as well as pass exams. Includes self-assessment, focussing on simple arithmetical calculation results from analytical data. Additional section on basic calculations in pharmaceutical analysis More detail on the capillary electrophoresis of proteins A discussion of some of the new types of HPLC column and on solvent selectivity in HPLC Additional material inserted on the control of the quality of analytical methods, mass spectrometry and high pressure liquid chromatography Additional self-assessment exercises

Encyclopedia Of Analytical Science Book PDF
✏Book Title : Encyclopedia of Analytical Science
✏Author :
✏Publisher : Elsevier
✏Release Date : 2019-04-02
✏Pages : 5109
✏ISBN : 9780081019849
✏Available Language : English, Spanish, And French

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✏Encyclopedia of Analytical Science Book Summary : The third edition of the Encyclopedia of Analytical Science is a definitive collection of articles covering the latest technologies in application areas such as medicine, environmental science, food science and geology. Meticulously organized, clearly written and fully interdisciplinary, the Encyclopedia of Analytical Science provides foundational knowledge across the scope of modern analytical chemistry, linking fundamental topics with the latest methodologies. Articles will cover three broad areas: analytical techniques (e.g., mass spectrometry, liquid chromatography, atomic spectrometry); areas of application (e.g., forensic, environmental and clinical); and analytes (e.g., arsenic, nucleic acids and polycyclic aromatic hydrocarbons), providing a one-stop resource for analytical scientists. Offers readers a one-stop resource with access to information across the entire scope of modern analytical science Presents articles split into three broad areas: analytical techniques, areas of application and and analytes, creating an ideal resource for students, researchers and professionals Provides concise and accessible information that is ideal for non-specialists and readers from undergraduate levels and higher

Handbook Of Capillary And Microchip Electrophoresis And Associated Microtechniques Third Edition Book PDF
✏Book Title : Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques Third Edition
✏Author : James P. Landers
✏Publisher : CRC Press
✏Release Date : 2007-12-18
✏Pages : 1592
✏ISBN : 1420004956
✏Available Language : English, Spanish, And French

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✏Handbook of Capillary and Microchip Electrophoresis and Associated Microtechniques Third Edition Book Summary : Although capillary electrophoresis (CE) technology has evolved quickly from the research laboratory into practical application in numerous fields, many scientists still debate its merits. While the body of international CE literature continues to expand dramatically, experts still question whether it has provided the speed, resolving power, peak capacity, sensitivity, robustness, and cost-reduction promised by its pioneers. Responding to these criticisms, this third edition brings together cutting-edge researchers to demonstrate the utility of CE across a broad spectrum of disciplines including— Forensic science Medical diagnostics Pharmaceutical science Genetic analysis Biotechnology Fluid mechanics Environmental science Biomedical research Nanotechnology Proteomics Detailed Analysis of New Methodologies and Applications Eagerly awaited by researchers and technicians who transformed the first two editions into bestsellers, this latest volume once again delivers. Emphasizing microseparations and microfluidics, the Handbook of Capillary and Microchip Electrophoresis, Third Edition features new chapters describing the use of microchip electrophoresis and associated microtechniques, with a focus on the extraordinary breadth of work undertaken to expand CE methodologies in recent years. Aided by contributions from leading international experts, this text remains a seminal reference for numerous chemistry, biology, and engineering fields.

Capillary Electromigration Separation Methods Book PDF
✏Book Title : Capillary Electromigration Separation Methods
✏Author : Colin F. Poole
✏Publisher : Elsevier
✏Release Date : 2018-04-13
✏Pages : 626
✏ISBN : 9780128096147
✏Available Language : English, Spanish, And French

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✏Capillary Electromigration Separation Methods Book Summary : Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins. Edited and authored by world-leading capillary electrophoresis experts Presents comprehensive coverage on the subject Includes extensive referencing that facilitates the identification of key research developments Provides more than 50 figures and tables that aid in the retention of key concepts

Chiral Capillary Electrophoresis In Current Pharmaceutical And Biomedical Analysis Book PDF
✏Book Title : Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis
✏Author : Peter Mikuš
✏Publisher : BoD – Books on Demand
✏Release Date : 2012-08-29
✏Pages : 210
✏ISBN : 9789535106579
✏Available Language : English, Spanish, And French

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✏Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis Book Summary : The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques.

Capillary Electrophoresis Mass Spectrometry Ce Ms  Book PDF
✏Book Title : Capillary Electrophoresis Mass Spectrometry CE MS
✏Author : Gerhardus de Jong
✏Publisher : John Wiley & Sons
✏Release Date : 2016-09-13
✏Pages : 368
✏ISBN : 9783527339242
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Mass Spectrometry CE MS Book Summary : This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields. Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.

Analysis Of Pharmaceuticals By Capillary Electrophoresis Book PDF
✏Book Title : Analysis of Pharmaceuticals by Capillary Electrophoresis
✏Author : Kevin D. Altria
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-04-17
✏Pages : 285
✏ISBN : 9783322850119
✏Available Language : English, Spanish, And French

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✏Analysis of Pharmaceuticals by Capillary Electrophoresis Book Summary : Dieser erste Titel einer ganzen Serie von anwendungsbezogenen Handbüchern zur Kapillarelektrophorese beschäftigt sich mit der Analytik von pharmazeutischen Substanzen. Dabei werden verschiedene Techniken praxisnah erläutert. Jeder, der im Labor - ob wissenschaftlich oder praxisnah - mit der Analyse von oft chiralen Pharmazeutika konfrontiert ist, wird viele Hinweise und Tips für seine Arbeit finden.USP: Einzige Monographie zur Analyse von Pharmazeutika mit CE This book describes the current state of the art for the analysis of pharmaceuticals by capillary electrophoresis and contains several hundred references to specific applications and methods. The main purpose of the book is to present the application possibilities of CE an therefore tabulated application data are provided. Chapters of the book are devoted to providing details of individual application areas such as chiral analysis, determination of drug related impurities, determination of drug counter-ions, drug residue monitoring and main component assay. An introductory chapter provides theoretical background to CE an related techniques. A chapter is dedicated to capillary electrochromatography which highlights the importance this technique currently possesses. Successful regulatory acceptance of CE methods is also described. A comprehensive chapter covers method validation aspects. Other chapters include discrete areas such as the use of non-aqueous solvents, forensic applications of CE, the application of experimental designs, determination of drugs in biofluids, and the analysis of vitamins by CE.

Capillary Electrophoresis In Chiral Analysis Book PDF
✏Book Title : Capillary Electrophoresis in Chiral Analysis
✏Author : Bezhan Chankvetadze
✏Publisher : John Wiley & Sons
✏Release Date : 1997-12-29
✏Pages : 572
✏ISBN : 0471974153
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis in Chiral Analysis Book Summary : Capillary Electrophoresis in Chiral Analysis Bezhan Chankvetadze Tbilisi State University, Republic of Georgia The application of capillary electrophoresis (CE) to the field of chiral analysis has exploded recently. The advantages of capillary electrophoresis - extremely high peak efficiency, excellent compatibility with biological samples, short analysis time, simplicity, versatility and low cost - are perfect for the accurate measurement of optical purity, increasingly important in the regulation-ruled pharmaceutical industry. Although there have been a number of books on capillary electrophoresis and chiral analysis separately, as yet there has been no dedicated monograph on the application of capillary electrophoresis to chiral analysis. This book bridges the gap. Capillary Electrophoresis in Chiral Analysis charts the evolution of chiral capillary electrophoresis and describes new types of chiral selectors and mechanistic aspects of chiral recognition. While on the one hand, it is an excellent introduction to newcomers, on the other, it is of practical use to experienced researchers in the field wishing to solve a particular separation problem. It includes an alphabetical list of chiral compounds resolved using CE with appropriate references, which any one working in the field will find invaluable.

Pharmaceutical And Biomedical Applications Of Capillary Electrophoresis Book PDF
✏Book Title : Pharmaceutical and Biomedical Applications of Capillary Electrophoresis
✏Author : S.M. Lunte
✏Publisher : Elsevier
✏Release Date : 1996-08-13
✏Pages : 508
✏ISBN : 0080538711
✏Available Language : English, Spanish, And French

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✏Pharmaceutical and Biomedical Applications of Capillary Electrophoresis Book Summary : The book describes the theory and applications of Capillary Electrophoresis (CE) in the field of pharmaceutical and biomedical analysis. It is targeted towards users who are intimately involved in analytical problems, especially those which involve small samples. This book presents the technique of capillary electrophoresis from the point of view of the serious hands-on use in the field of pharmaceutical and biomedical analysis. An overview of general theory is presented to acquaint the novice with the fundamental principles. A more theoretical approach is taken in the presentation of electrokinetic chromatography. The next chapter discusses advances in column technologies, the preceding chapters having provided a foundation as to how separations occur. In the next three chapters, recognized experts in their fields present fundamentals and state-of-the-art techniques in the areas of optical, electrochemical and mass spectrometric detection. The major focus of the remaining chapters is on applications. This includes the analysis of pharmaceuticals, amino acids and peptides, macromolecules, nucleosides, nucleotides and oligonucleotides. The use of CE for analysis of small ions and separation of biological particles is also discussed. The issue of sample preparation for analysis by CE is addressed, especially as it relates to clinical analysis.

Capillary Electrophoresis Book PDF
✏Book Title : Capillary Electrophoresis
✏Author : S.F.Y. Li
✏Publisher : Elsevier
✏Release Date : 1992-07-31
✏Pages : 581
✏ISBN : 0080858600
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Book Summary : Capillary Electrophoresis (CE) has had a very significant impact on the field of analytical chemistry in recent years as the technique is capable of very high resolution separations, requiring only small amounts of samples and reagents. Furthermore, it can be readily adapted to automatic sample handling and real time data processing. Many new methodologies based on CE have been reported. Rapid, reproducible separations of extremely small amounts of chemicals and biochemicals, including peptides, proteins, nucleotides, DNA, enantiomers, carbohydrates, vitamins, inorganic ions, pharmaceuticals and environmental pollutants have been demonstrated. A wide range of applications have been developed in greatly diverse fields, such as chemical, biotechnological, environmental and pharmaceutical analysis. This book covers all aspects of CE, from the principles and technical aspects to the most important applications. It is intended to meet the growing need for a thorough and balanced treatment of CE. The book will serve as a comprehensive reference work. Both the experienced analyst and the newcomer will find the text useful.

Capillary Electrophoresis Guidebook Book PDF
✏Book Title : Capillary Electrophoresis Guidebook
✏Author : Kevin D. Altria
✏Publisher : Springer Science & Business Media
✏Release Date : 1996
✏Pages : 349
✏ISBN : 9781592595396
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Guidebook Book Summary : Capillary Electrophoresis Guidebook offers both newcomers and experienced research workers hands-on guidance to performing capillary electrophoresis. It provides sufficient practical advice to permit you to develop and optimize your own separations, along with extensive troubleshooting sections to overcome practical difficulties. The book contains operating instructions for standard commercially available instruments and includes guidelines for activities such as changing capillaries, method development, quantitative procedures, optimizing sensitivity, and the validation of methods. Review chapters written by leading experts discuss micellar electrokinetic capillary chromatography, capillary gel electrophoresis, advanced sampling techniques, and electrochromatography. Important application areas such as the analysis of proteins, peptides, amino acids, pharmaceuticals, chiral compounds, and nucleic acids are also treated.

Handbook Of Pharmaceutical Analysis Book PDF
✏Book Title : Handbook of Pharmaceutical Analysis
✏Author : Lena Ohannesian
✏Publisher : CRC Press
✏Release Date : 2001-11-09
✏Pages : 608
✏ISBN : 0824741943
✏Available Language : English, Spanish, And French

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✏Handbook of Pharmaceutical Analysis Book Summary : Exploring the analysis of pharmaceuticals, including polymorphic forms, this book discusses regulatory requirements in pharmaceutical product development and pharmaceutical testing. It covers methods of drug separation and procedures such as capillary electrophoresis for chromatographic separation of molecules. Additional topics include drug formulation analysis using vibrational and magnetic resonance spectroscopy and identification of drug metabolites and decomposition products using such techniques as mass spectrometry. The book provides more than 300 tables, equations, drawings, and photographs, and convenient, easy-to-use indices, facilitating quick access to each topic.

Chromatographic Analysis Of Pharmaceuticals Second Edition Book PDF
✏Book Title : Chromatographic Analysis of Pharmaceuticals Second Edition
✏Author : John A. Adamovics
✏Publisher : CRC Press
✏Release Date : 1996-10-11
✏Pages : 542
✏ISBN : 0824797760
✏Available Language : English, Spanish, And French

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✏Chromatographic Analysis of Pharmaceuticals Second Edition Book Summary : Updated and revised throughout. Second Edition explores the chromatographic methods used for the measurement of drugs, impurities, and excipients in pharmaceutical preparations--such as tablets, ointments, and injectables. Contains a 148-page table listing the chromatographic data of over 1300 drugs and related substances--including sample matrix analyzed, sample handling procedures, column packings, mobile phase, mode of detection, and more.

Handbook Of Capillary Electrophoresis Applications Book PDF
✏Book Title : Handbook of Capillary Electrophoresis Applications
✏Author : H. Shintani
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 738
✏ISBN : 9789400915619
✏Available Language : English, Spanish, And French

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✏Handbook of Capillary Electrophoresis Applications Book Summary : Over the last decade, high performance Capillary electrophoresis (HPCE) has emerged as a powerful and versatile separation technique that promises to rival high performance liquid chromatography when applied to the separation of both charged and neutral species. The high speed and high separation efficiency which can be attained using any of the various modes of HPCE has resulted in the increased use of the technique in a range of analytical environments. The procedures are, however, still in the early stages of development and several barriers remain to their adoption as the technique of choice for a range of analytical problems. One such barrier is the selection and optimization of the conditions required to achieve reproducible separations of analytes and it is in this area that this new book seeks to give assistance. The book is written by an international team of authors, drawn from both academic and industrial users, and the manufacturers of instruments. At its heart are a number of tables, divided into specific application areas. These give details of published separations of a wide range of archetypal analytes, the successful separation conditions and the matrix in which they were presented. These tables are based on separations reported since 1992 and are fully referenced to the original literature. The tables are supported by discussions of the problems that a particular area presents and the strategies and solutions adopted to overcome them. The general areas covered are biochemistry, pharmaceutical science, bioscience, ion analysis, food analysis and environmental science.

Practical Capillary Electrophoresis Book PDF
✏Book Title : Practical Capillary Electrophoresis
✏Author : Robert Weinberger
✏Publisher : Elsevier
✏Release Date : 2000-04-18
✏Pages : 462
✏ISBN : 9780080539348
✏Available Language : English, Spanish, And French

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✏Practical Capillary Electrophoresis Book Summary : In the 1980s, capillary electrophoresis (CE) joined high-performance liquid chromatography (HPLC) as the most powerful separation technique available to analytical chemists and biochemists. Published research using CE grew from 48 papers in the year of commercial introduction (1988) to 1200 in 1997. While only a dozen major pharmaceutical and biotech companies have reduced CE to routine practice, the applications market is showing real or potential growth in key areas, particularly in the DNA marketplace for genomic mapping and forensic identification. For drug development involving small molecules (including chiral separations), one CE instrument can replace 10 liquid chromatographs in terms of speed of analysis. CE also uses aqueous rather than organic solvents and is thus environmentally friendlier than HPLC. The second edition of Practical Capillary Electrophoresis has been extensively reorganized and rewritten to reflect modern usage in the field, with an emphasis on commercially available apparatus and reagents. This authoritative and very comprehensible treatment builds on the author's extensive experience as an instructor of short courses for the American Chemical Society and for industry. Illustrated with detailed diagrams of electrophoretic phenomena Offers step-by-step methods development schemes Presents techniques for developing quantitative, robust, and precise methods Includes an extensive troubleshooting guide Updates and greatly expands on the first edition-more than 50% of the text is new Written by an internationally recognized scientist who is an instructor for American Chemical Society short courses on HPCE

Chemometric Methods In Capillary Electrophoresis Book PDF
✏Book Title : Chemometric Methods in Capillary Electrophoresis
✏Author : Grady Hanrahan
✏Publisher : John Wiley & Sons
✏Release Date : 2009-10-22
✏Pages : 336
✏ISBN : 0470530189
✏Available Language : English, Spanish, And French

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✏Chemometric Methods in Capillary Electrophoresis Book Summary : Use chemometric techniques to develop optimum separation conditions for capillary electrophoreses For all its advantages, capillary electrophoresis (CE) also carries significant disadvantages for the researcher. Offering a unique blend of information from authors active in a variety of developments of chemometrics in CE, Chemometric Methods in Capillary Electrophoresis presents modern chemometric methods as an alternative to help alleviate the problems commonly encountered during routine analysis and method development. Focusing on current chemometric methods utilized in CE endeavours by research-active experts in the field, the book begins with a thorough introduction to CE and chemometric-related concepts and the need for modern chemometric methods in CE. Part 1 discusses differing types of screening designs and response surface methodology¿in an¿application based format Part 2 includes vital discussion on various exploratory data analysis, prediction, and classification techniques utilized in CE-related studies Part 3 provides practical information on modelling quantitative structure relationships Part 4 explores transformation techniques, in particular fundamental studies and applications of cross-correlation and Hadamard Transform Electrophoresis Showing how chemometric methods are applied in a wide array of applications including biological, medical, pharmaceutical, food, forensic, and environmental science, Chemometric Methods in Capillary Electrophoresis is not only highly significant to capillary electrophoresis-based endeavours, but instructive for investigators active in other areas of separation science who could benefit from its informative content.

Pharmaceutical And Biomedical Applications Of Liquid Chromatography Book PDF
✏Book Title : Pharmaceutical and Biomedical Applications of Liquid Chromatography
✏Author : W.J. Lough
✏Publisher : Newnes
✏Release Date : 2013-10-22
✏Pages : 393
✏ISBN : 9780080984544
✏Available Language : English, Spanish, And French

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✏Pharmaceutical and Biomedical Applications of Liquid Chromatography Book Summary : This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures. The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored. Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media. The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

Capillary Electrophoresis Principles And Practice Book PDF
✏Book Title : Capillary Electrophoresis Principles and Practice
✏Author : Reinhard Kuhn
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-03-07
✏Pages : 375
✏ISBN : 9783642780585
✏Available Language : English, Spanish, And French

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✏Capillary Electrophoresis Principles and Practice Book Summary : Capillary electrophoresis (CE) is a brand-new analytical me- thod with the capability of solving many analytical separa- tion problems very fast and economically. This method gives new information about the investigated substances which can- not easily be obtained by other means. CE has become an established method only recently, but will be implemented in almost every analytical laboratory in industry, service units and academia in the near future. The most important fields of CE application are pharmaceutical and biochemical research and quality control. The authors have exhaustive practical experience in the application of CE methods in the pharmaceutical industry and provide the reader with a comprehensive treatment of this method. The main focus is on how to solve problems when applying CE in the laboratory. Physico-chemical theory is only dealt with in depth when necessary to understand the underlying separation mechanisms in order to solve your problems at the analytical bench. An addendum includes tables on the preparation of buffers and recommended further reading.

Validation Of Analytical Methods For Pharmaceutical Analysis Book PDF
✏Book Title : Validation of Analytical Methods for Pharmaceutical Analysis
✏Author : Oona McPolin
✏Publisher : Lulu.com
✏Release Date : 2009-05-01
✏Pages : 152
✏ISBN : 9780956152817
✏Available Language : English, Spanish, And French

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✏Validation of Analytical Methods for Pharmaceutical Analysis Book Summary : This book provides a comprehensive guide on validating analytical methods. Key features: Full review of the available regulatory guidelines on validation and in particular, ICH. Sections of the guideline, Q2(R1), have been reproduced in this book with the kind permission of the ICH Secretariat; Thorough discussion of each of the validation characteristics (Specificity; Linearity; Range; Accuracy; Precision; Detection Limit; Quantitation Limit; Robustness; System Suitability) plus practical tips on how they may be studied; What to include in a validation protocol with advice on the experimental procedure to follow and selection of appropriate acceptance criteria; How to interpret and calculate the results of a validation study including the use of suitable statistical calculations; A fully explained case study demonstrating how to plan a validation study, what to include in the protocol, experiments to perform, setting acceptance criteria, interpretation of the results and reporting the study.

📒Pharmaceutical Analysis ✍ David G. Watson

Pharmaceutical Analysis Book PDF
✏Book Title : Pharmaceutical Analysis
✏Author : David G. Watson
✏Publisher : Churchill Livingstone
✏Release Date : 2005
✏Pages : 382
✏ISBN : UOM:39015060575084
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Analysis Book Summary : This introductory text highlights the most important aspects of a wide range of techniques used in the control of the quality of pharmaceuticals. Written with the needs of the student in mind, this clear, practical guide includes self-testing sections with arithmetical examples and tests to help students brush up on their arithmetical skills in an applied context. Covers all of the most important analysis techniques in one book. Concentrates on the most important points with just the right level of detail. Summarizes the relevant theory but avoids becoming too esoteric. Features chapter summaries, key points and self-assessment boxes. Includes arithmetical calculations of results in the self-assessment exercises. Additional section on basic calculations in pharmaceutical analysis More detail on the capillary electrophoresis of proteins A discussion of some of the new types of HPLC column and on solvent selectivity in HPLC Additional material inserted on the control of the quality of analytical methods, mass spectrometry and high pressure liquid chromatography Additional self-assessment exercises

Nmr Spectroscopy In Pharmaceutical Analysis Book PDF
✏Book Title : NMR Spectroscopy in Pharmaceutical Analysis
✏Author : Iwona Wawer
✏Publisher : Elsevier
✏Release Date : 2017-07-07
✏Pages : 528
✏ISBN : 9780080951522
✏Available Language : English, Spanish, And French

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✏NMR Spectroscopy in Pharmaceutical Analysis Book Summary : For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

Separation Methods In Drug Synthesis And Purification Book PDF
✏Book Title : Separation Methods in Drug Synthesis and Purification
✏Author : Klara Valko
✏Publisher : Elsevier
✏Release Date : 2000-10-13
✏Pages : 612
✏ISBN : 0080541097
✏Available Language : English, Spanish, And French

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✏Separation Methods in Drug Synthesis and Purification Book Summary : Separation Methods in Drug Synthesis and Purification

📒Electrokinetic Phenomena ✍ Anurag Rathore

Electrokinetic Phenomena Book PDF
✏Book Title : Electrokinetic Phenomena
✏Author : Anurag Rathore
✏Publisher : CRC Press
✏Release Date : 2003-09-16
✏Pages : 496
✏ISBN : 9780824756598
✏Available Language : English, Spanish, And French

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✏Electrokinetic Phenomena Book Summary : Electrokinetic Phenomena emphasizes the impact of methods such as capillary zone electrophoresis, capillary electrochromatography, and capillary gel electrophoresis on the analysis of biomolecules. This reference reveals the electrokinetic phenomena that underlie high-performance electro-based analytical tools and vividly depicts how electrodriven analytical tools revolutionize and expedite chemical, pharmaceutical, and biotechnological analysis. An authoritative overview, the book provides effective pathways for large-scale biomedical applications and describes how microfabricated and automated devices enhance and accelerate the analysis of biologically important molecules.