Breaking Tolerance To Pancreatic Cancer Unresponsiveness To Chemotherapy

Breaking Tolerance To Pancreatic Cancer Unresponsiveness To Chemotherapy Book PDF
✏Book Title : Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy
✏Author : Ganji Purnachandra Nagaraju
✏Publisher : Academic Press
✏Release Date : 2019-02-26
✏Pages : 223
✏ISBN : 9780128176627
✏Available Language : English, Spanish, And French

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✏Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy Book Summary : Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy. Modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property by introducing new strategies and drugs Provides information about on-going research as well as clinical data on pancreatic cancer and detailed descriptions about therapeutic options for easy understanding Utilizes full color figures to help the understanding of the content and tables for easy comparison of information as well as quick access to it

📒Theranostic Approach For Pancreatic Cancer ✍ Ganji Purnachandra Nagaraju

Theranostic Approach For Pancreatic Cancer Book PDF
✏Book Title : Theranostic Approach for Pancreatic Cancer
✏Author : Ganji Purnachandra Nagaraju
✏Publisher : Academic Press
✏Release Date : 2019-08-19
✏Pages : 410
✏ISBN : 9780128194584
✏Available Language : English, Spanish, And French

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✏Theranostic Approach for Pancreatic Cancer Book Summary : Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer“/li> Discusses treatment options available currently and prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment

Improving The Therapeutic Ratio In Head And Neck Cancer Book PDF
✏Book Title : Improving the Therapeutic Ratio in Head and Neck Cancer
✏Author :
✏Publisher : Academic Press
✏Release Date : 2019-10-04
✏Pages : 376
✏ISBN : 9780128178690
✏Available Language : English, Spanish, And French

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✏Improving the Therapeutic Ratio in Head and Neck Cancer Book Summary : Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites. Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data

Drug Efflux Pumps In Cancer Resistance Pathways From Molecular Recognition And Characterization To Possible Inhibition Strategies In Chemotherapy Book PDF
✏Book Title : Drug Efflux Pumps in Cancer Resistance Pathways From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy
✏Author :
✏Publisher : Academic Press
✏Release Date : 2019-11-07
✏Pages : 394
✏ISBN : 9780128141410
✏Available Language : English, Spanish, And French

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✏Drug Efflux Pumps in Cancer Resistance Pathways From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy Book Summary : Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance. Offers comprehensive and detailed descriptions of the basic aspects of efflux pumps in a very schematic and didactic manner Describes the involvement of efflux pumps in cancer resistance in different cancer types Encompasses an updated overview on state-of-the-art approaches that capitalize on their inhibition to improve chemotherapy and overcome resistance

Biological Mechanisms And The Advancing Approaches To Overcoming Cancer Drug Resistance Book PDF
✏Book Title : Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance
✏Author : Andrew Freywald
✏Publisher : Academic Press
✏Release Date : 2020-12-04
✏Pages : 308
✏ISBN : 9780128213117
✏Available Language : English, Spanish, And French

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✏Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance Book Summary : Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges. Provides the most updated knowledge on the mechanisms of cancer drug resistance and the emerging therapeutic approaches reviewed by experts in the field Brings detailed analyses of most important recently reported developments related to drug resistance and their relevance to overcoming it in cancer patients Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies

A Theranostic And Precision Medicine Approach For Female Specific Cancers Book PDF
✏Book Title : A Theranostic and Precision Medicine Approach for Female Specific Cancers
✏Author : Rama Rao Malla
✏Publisher : Academic Press
✏Release Date : 2020-11-06
✏Pages : 318
✏ISBN : 9780128226926
✏Available Language : English, Spanish, And French

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✏A Theranostic and Precision Medicine Approach for Female Specific Cancers Book Summary : A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of biomedical field who need to understand the most recent and promising approaches to manage FSCs. Explores new diagnostic biomarkers surrounding the early detection and prognosis of FSCs Examines new genetic and molecularly targeted approaches for the treatment of these aggressive diseases Discusses new theranostic approaches that combine diagnosis and treatment through the use of nanotechnology in FSCs Addresses how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care

Special Listing International Cancer Research Data Bank V 334 1980 Book PDF
✏Book Title : Special listing International Cancer Research Data Bank v 334 1980
✏Author :
✏Publisher :
✏Release Date : 1980
✏Pages :
✏ISBN : STANFORD:24501854122
✏Available Language : English, Spanish, And French

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✏Special listing International Cancer Research Data Bank v 334 1980 Book Summary :

Chemical Abstracts Book PDF
✏Book Title : Chemical Abstracts
✏Author :
✏Publisher :
✏Release Date : 2002
✏Pages :
✏ISBN : UOM:39015057321369
✏Available Language : English, Spanish, And French

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✏Chemical Abstracts Book Summary :