Bioreactor Modeling

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  • Author : Jerome Morchain
  • Publisher : Elsevier
  • Pages : 218 pages
  • ISBN : 0081011660
  • Rating : /5 from reviews
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Download or Read online Bioreactor Modeling full in PDF, ePub and kindle. this book written by Jerome Morchain and published by Elsevier which was released on 06 October 2017 with total page 218 pages. We cannot guarantee that Bioreactor Modeling book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand, have the ability to modulate the rate of substrate assimilation. Moreover, the nature of the biochemical transformations results from a compromise between the needs of the cell and the available resources. This book revisits the modeling of bioreactors using a multi-scale approach. It addresses issues related to mixing, phase-to-phase transfers and the adaptation of microorganisms to variations in concentration, and explores the use of population balances for the simulation of bioreactors. By adopting a multidisciplinary perspective that draws on process engineering, fluid mechanics and microbiology, this book sheds new light on the particularity of bioprocesses in relation to physical and chemical phenomena. Presents a multiphase description of bioreactor modeling Includes a combination of concepts issued from different scientific fields to address a practical issue Provides a detailed description of the population balance concept as applied to biological systems Covers a set of illustrative examples of the interaction between hydrodynamics and biological response

Bioreactor Modeling

Bioreactor Modeling
  • Author : Jerome Morchain
  • Publisher : Elsevier
  • Release : 06 October 2017
GET THIS BOOK Bioreactor Modeling

Dynamic simulation of bioreactors is a challenge for both the industrial and academic worlds. Beyond the large number of physical and biological phenomena to be considered and the wide range of scales involved, the central difficulty lies in the need to account for the dynamic behavior of suspended microorganisms. In the case of chemical reactors, knowledge of the thermodynamic equilibrium laws at the interfaces makes it possible to produce macroscopic models by integrating local laws. Microorganisms, on the other hand,

Bioreactors Process and Analysis

Bioreactors  Process and Analysis
  • Author : Tapobrata Panda
  • Publisher : Tata McGraw-Hill Education
  • Release : 20 September 2021
GET THIS BOOK Bioreactors Process and Analysis

6. Bioreactor modeling -- Model - what is it? -- Definition of lumped and distributed parameter models -- Introduction to a few terminologies and theorems -- Modeling principles -- Steps in modeling -- Fundamental laws used in process modeling -- First-order systems -- Second-order systems -- Complexity of the model -- Parameter sensitivity -- Exercises -- References -- Appendix 6 -- 7. Transport processes in bioreactors -- Introduction -- Heat transfer -- Other parameters influencing transfer operations -- Exercises -- References -- 8. Controls

Solid State Fermentation Bioreactors

Solid State Fermentation Bioreactors
  • Author : David A. Mitchell,Nadia Krieger,Marin Berovic
  • Publisher : Springer Science & Business Media
  • Release : 02 August 2006
GET THIS BOOK Solid State Fermentation Bioreactors

This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. The authors survey bioreactor types in common use, and describe in depth how to plan a project, and model heat transfer phenomena. The book includes case studies, and a review of practical issues involved in bioreactor performance.

Computational Modeling in Biomechanics

Computational Modeling in Biomechanics
  • Author : Suvranu De,Farshid Guilak,Mohammad Mofrad
  • Publisher : Springer Science & Business Media
  • Release : 10 March 2010
GET THIS BOOK Computational Modeling in Biomechanics

Availability of advanced computational technology has fundamentally altered the investigative paradigm in the field of biomechanics. Armed with sophisticated computational tools, researchers are seeking answers to fundamental questions by exploring complex biomechanical phenomena at the molecular, cellular, tissue and organ levels. The computational armamentarium includes such diverse tools as the ab initio quantum mechanical and molecular dynamics methods at the atomistic scales and the finite element, boundary element, meshfree as well as immersed boundary and lattice-Boltzmann methods at the continuum

Landfill Bioreactor Design Operation

Landfill Bioreactor Design   Operation
  • Author : Timothy G. Townsend
  • Publisher : Routledge
  • Release : 19 December 2018
GET THIS BOOK Landfill Bioreactor Design Operation

Using biotechnology to help control landfill processes can mitigate costs, shorten the time needed to process solid waste, and ease the typical ecological damage to the land being used. This first-of-its-kind book provides regulators, designers, landfill owners, and operators with information that supports the utility of landfill bioreactors and provides design and operating criteria essential for the successful application of this technology. It pulls together laboratory, pilot, and full-scale experiences into one concise guide to designing and running municipal landfills

Bioreactors

Bioreactors
  • Author : Carl-Fredrik Mandenius
  • Publisher : John Wiley & Sons
  • Release : 16 February 2016
GET THIS BOOK Bioreactors

In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production,

Computational Modeling in Bioengineering and Bioinformatics

Computational Modeling in Bioengineering and Bioinformatics
  • Author : Nenad Filipovic
  • Publisher : Academic Press
  • Release : 09 October 2019
GET THIS BOOK Computational Modeling in Bioengineering and Bioinformatics

Computational Modeling in Bioengineering and Bioinformatics promotes complementary disciplines that hold great promise for the advancement of research and development in complex medical and biological systems, and in the environment, public health, drug design, and so on. It provides a common platform by bridging these two very important and complementary disciplines into an interactive and attractive forum. Chapters cover biomechanics and bioimaging, biomedical decision support system, data mining, personalized diagnoses, bio-signal processing, protein structure prediction, tissue and cell engineering, biomedical

Bioreactor System Design

Bioreactor System Design
  • Author : Juan A. Asenjo
  • Publisher : CRC Press
  • Release : 17 November 1994
GET THIS BOOK Bioreactor System Design

Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such as strain and media selection, that have an overwhelming influence on all further operations, is emphasized.;This work is intended for biochemical, chemical and bioprocess engineers; biotechnologists; industrial biochemists; micro- and

DESIGN IMPLEMENTATION AND MODELING OF A TRANSTUBULAR BIOREACTOR FOR THE GROWTH OF MAMMALIAN CELLS BIOREACTOR HYBRIDOMA CELLS

DESIGN  IMPLEMENTATION AND MODELING OF A TRANSTUBULAR BIOREACTOR FOR THE GROWTH OF MAMMALIAN CELLS  BIOREACTOR  HYBRIDOMA CELLS
  • Author : CRAIG REED HALBERSTADT
  • Publisher : Unknown
  • Release : 20 September 1991
GET THIS BOOK DESIGN IMPLEMENTATION AND MODELING OF A TRANSTUBULAR BIOREACTOR FOR THE GROWTH OF MAMMALIAN CELLS BIOREACTOR HYBRIDOMA CELLS

antibody production. Whether the increase in antibody production is due to autocrine/paracrine factors, local pH concentrations, pulsatile delivery of growth factors or some other mechanism is unknown and requires further study.

Fixed Bed Hybrid Bioreactor

Fixed Bed Hybrid Bioreactor
  • Author : Sushovan Sarkar
  • Publisher : Springer Nature
  • Release : 27 January 2021
GET THIS BOOK Fixed Bed Hybrid Bioreactor

This book describes a simplified approach to the modelling and process design of a fixed bed hybrid bioreactor for wastewater treatment. In this work a simplified model for hybrid bioreactor is developed to determine output parameters like exiting substrate concentration in bulk liquid, average substrate flux in the biofilm, effective and total biofilm thickness. The model is based on mass balance of both carbonaceous substrate and biomass under suspended and attached growth simultaneously along with substrate mass transport into the

Bioreactors

Bioreactors
  • Author : Goutam Saha,Alok Barua,Satyabroto Sinha
  • Publisher : CRC Press
  • Release : 01 December 2017
GET THIS BOOK Bioreactors

Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to

Biological Reaction Engineering

Biological Reaction Engineering
  • Author : Elmar Heinzle,Irving J. Dunn,John Ingham,Jiří E. Přenosil
  • Publisher : John Wiley & Sons
  • Release : 26 April 2021
GET THIS BOOK Biological Reaction Engineering

This practical book presents the modeling of dynamic biological engineering processes in a readily comprehensible manner, using the unique combination of simplified fundamental theory and direct hands-on computer simulation. The mathematics is kept to a minimum, and yet the 60 examples illustrate almost every aspect of biological engineering science, with each one described in detail, including the model equations. The programs are written in the modern user-friendly simulation language Berkeley Madonna, which can be run on both Windows PC and Power-Macintosh