Biomarkers In Bipolar Disorders

Biomarkers Of Postpartum Psychiatric Disorders Book PDF
✏Book Title : Biomarkers of Postpartum Psychiatric Disorders
✏Author : Jennifer L. Payne
✏Publisher : Academic Press
✏Release Date : 2019-09-28
✏Pages : 236
✏ISBN : 9780128158364
✏Available Language : English, Spanish, And French

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✏Biomarkers of Postpartum Psychiatric Disorders Book Summary : Biomarkers of Postpartum Psychiatric Disorders provides an up-to-date reference on the current research relating to biomarkers in psychiatric disorders, including major depressive disorder, OCD and bipolar disorder in the immediate postpartum time-period. It is the only reference on the market that synthesizes and interprets available data and reviews clinical phenotypes. Topics cover hormonal contributions, immunology, epigenetics and neuroimaging. While the risk of psychiatric illness during pregnancy appears to be equivalent to the risk at any other time in a woman’s life, the risk in the immediate postpartum time period is dramatically increased, hence the importance of the discussions in this title. Identifies epigenetic, hormonal, immunological and neuroimaging biomarkers Provides biomarkers for depression, OCD and psychosis Includes clinical phenotypes for psychiatric disorders Discusses future research and directions in the field

📒Biomarkers In Psychiatry ✍ Judith Pratt

Biomarkers In Psychiatry Book PDF
✏Book Title : Biomarkers in Psychiatry
✏Author : Judith Pratt
✏Publisher : Springer
✏Release Date : 2019-01-05
✏Pages : 437
✏ISBN : 9783319996424
✏Available Language : English, Spanish, And French

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✏Biomarkers in Psychiatry Book Summary : This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

Reviews On Biomarker Studies In Psychiatric And Neurodegenerative Disorders Book PDF
✏Book Title : Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders
✏Author : Paul C. Guest
✏Publisher : Springer
✏Release Date : 2019-02-12
✏Pages : 328
✏ISBN : 9783030055424
✏Available Language : English, Spanish, And French

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✏Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders Book Summary : This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.

Neuroprogression And Staging In Bipolar Disorder Book PDF
✏Book Title : Neuroprogression and Staging in Bipolar Disorder
✏Author : Flávio Kapczinski
✏Publisher : Oxford University Press, USA
✏Release Date : 2015
✏Pages : 344
✏ISBN : 9780198709992
✏Available Language : English, Spanish, And French

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✏Neuroprogression and Staging in Bipolar Disorder Book Summary : Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--

📒Advances In Treatment Of Bipolar Disorders ✍ Edited by Terence A. Ketter M.D.

Advances In Treatment Of Bipolar Disorders Book PDF
✏Book Title : Advances in Treatment of Bipolar Disorders
✏Author : Edited by Terence A. Ketter M.D.
✏Publisher : American Psychiatric Pub
✏Release Date : 2015-04-09
✏Pages : 338
✏ISBN : 9781585624171
✏Available Language : English, Spanish, And French

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✏Advances in Treatment of Bipolar Disorders Book Summary : Advances in Treatment of Bipolar Disorders provides clinicians with a well-written and timely guide to the most recent advances in the treatment of patients with this complex disorder. Staying abreast of new research developments and treatment options presents a daunting challenge, but the editor and coauthors have compiled the most important evidence-based findings from controlled studies and U.S. Food and Drug Administration approved indications, facilitating integration of these findings into clinical practice. This volume strives to provide clinicians with the necessary information to enable them to balance the likelihood of benefit (using “number needed to treat” analyses) versus harm (using “number needed to harm” analyses) in order to provide individualized, state-of-the-art, evidence-based care. The most current research findings are complemented by the authors’ extensive personal clinical experiences, resulting in a volume that reflects the most up-to-date thinking about the diagnosis and management of bipolar disorder. Advances in Treatment of Bipolar Disorders belongs in every mental health clinician’s library.

Proteomic Approaches To Identify Blood Based Biomarkers For Depression And Bipolar Disorders Book PDF
✏Book Title : Proteomic Approaches to Identify Blood based Biomarkers for Depression and Bipolar Disorders
✏Author :
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1053707916
✏Available Language : English, Spanish, And French

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✏Proteomic Approaches to Identify Blood based Biomarkers for Depression and Bipolar Disorders Book Summary : ABSTRACT: Introduction : Major depressive disorder (MDD) and bipolar disorder (BD) are leading causes of disability worldwide, yet many people remain undiagnosed, are misdiagnosed, and/or ineffectively treated. Diagnosis relies on the clinical assessment of symptoms, and there is currently no molecular or brain-imaging diagnostic test available. Identifying and validating protein biomarkers could provide a more accurate and objective means of diagnosis. Areas covered : Proteomics is a powerful tool that enables the identification and quantification of novel candidate biomarkers of disease. In this review, we discuss the role of proteomic technologies in biomarker discovery and validation, peripheral blood as a source of protein biomarkers, statistical methods for analyzing proteomic data, and some existing challenges in the field. We also review a selection of previously published studies focused on identifying blood-based diagnostic protein biomarkers of MDD and BD within a ten-year period. Expert commentary : Proteomic studies have led to the identification of numerous potential biomarkers of MDD and BD. However, clinical validation and translation into clinical practice have not yet been achieved. Conducting large-scale validation studies and addressing various factors that limit the reproducibility of the proteomic findings are key to ensure that robust and reliable biomarker tests are developed and clinically validated.

Proteomic And Ionomic Study For Identification Of Biomarkers In Biological Fluid Samples Of Patients With Psychiatric Disorders And Healthy Individuals Book PDF
✏Book Title : Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals
✏Author : Jemmyson Romário de Jesus
✏Publisher : Springer Nature
✏Release Date : 2019-10-22
✏Pages : 88
✏ISBN : 9783030294731
✏Available Language : English, Spanish, And French

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✏Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals Book Summary : This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.

The Handbook Of Neuropsychiatric Biomarkers Endophenotypes And Genes Book PDF
✏Book Title : The Handbook of Neuropsychiatric Biomarkers Endophenotypes and Genes
✏Author : Michael Ritsner
✏Publisher : Springer Science & Business Media
✏Release Date : 2009-04-21
✏Pages : 273
✏ISBN : 9781402094644
✏Available Language : English, Spanish, And French

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✏The Handbook of Neuropsychiatric Biomarkers Endophenotypes and Genes Book Summary : Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

📒Bipolar Disorder In Youth ✍ Stephen M. Strakowski

Bipolar Disorder In Youth Book PDF
✏Book Title : Bipolar Disorder in Youth
✏Author : Stephen M. Strakowski
✏Publisher : Oxford University Press
✏Release Date : 2014-10-01
✏Pages : 400
✏ISBN : 9780199985371
✏Available Language : English, Spanish, And French

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✏Bipolar Disorder in Youth Book Summary : Bipolar disorders affect up to 3% of the world's population and are the 6th leading cause of disability worldwide. The estimated annual costs of bipolar disorder approach $50 billion in the United States, and the associated societal and personal suffering is immeasurable. Bipolar disorder is a lifelong illness that typically begins in mid-adolescence, thereby disrupting healthy developmental processes. It is also a progressive illness, making early intervention even more critical. As the disorder presents differently in youth as it does in adults, considerable controversy exists around the diagnosis in young people. The neurobiological factors leading to the onset of bipolar disorder reflect abnormalities in adolescent brain development. Bipolar disorder is strongly heritable and therefore, these developmental abnormalities likely represent the culmination of processes that precede the expression of symptoms. Current studies of children who are at risk for bipolar disorder are identifying these processes. Again, controversy exists about how to move these neuroscience gains forward to help affected individuals and, particularly to manage children at risk to delay or prevent the onset or progression of bipolar disorder. With these considerations in mind, Bipolar Disorder in Youth provides a timely, focused review of the diagnosis, treatment, and neurobiology of bipolar disorder in youth. It addresses current controversies and resolves those in which evidence is available. The book is organized into three sections based on these topics to provide comprehensive discussions to aid clinicians managing these individuals in their practices, as well as scientists trying to advance the field. The three editors are widely recognized experts in bipolar disorder, and the authors of each chapter represent international experts in the respective topics. Consequently, this book is the most comprehensive volume available discussing this important population and is a 'must' for the libraries of clinicians and scientists working with bipolar children and adolescents.

📒Immunopsychiatry ✍ Antonio L. Teixeira

Immunopsychiatry Book PDF
✏Book Title : Immunopsychiatry
✏Author : Antonio L. Teixeira
✏Publisher : Oxford University Press, USA
✏Release Date : 2019-01-18
✏Pages : 320
✏ISBN : 9780190884468
✏Available Language : English, Spanish, And French

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✏Immunopsychiatry Book Summary : In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

Proteomics And Metabolomics In Psychiatry Book PDF
✏Book Title : Proteomics and Metabolomics in Psychiatry
✏Author : D. Martins-de-Souza
✏Publisher : Karger Medical and Scientific Publishers
✏Release Date : 2014-05-23
✏Pages : 150
✏ISBN : 9783318026009
✏Available Language : English, Spanish, And French

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✏Proteomics and Metabolomics in Psychiatry Book Summary : This publication compiles data generated by proteomics and metabolomics about psychiatric disorders. Leading researchers in these fields review the basic principles of proteomics and metabolomics and propose the new directions to be followed in molecular psychiatry. The chapters divided into two sections – Schizophrenia/Psychotic Disorders and Mood Disorders – deal with findings in diverse tissues from human and preclinical models in order to unravel the biology and biochemistry behind the establishment and course of these illnesses as well as potential biomarkers for clinical applications. More than an update, this publication indicates the next steps to discover biomarkers and understand psychiatric disorders more comprehensively. This publication is valuable reading for psychiatrists, neuroscientists and analytical chemists interested in the basics of proteomics and metabolomics, psychiatric definitions and the most advanced hypotheses about the pathobiology of schizophrenia, depression and bipolar disorder.

📒Bipolar Disorder ✍ Nickolas B. Moore

Bipolar Disorder Book PDF
✏Book Title : Bipolar Disorder
✏Author : Nickolas B. Moore
✏Publisher : Nova Science Pub Incorporated
✏Release Date : 2013-01-01
✏Pages : 201
✏ISBN : 1626186669
✏Available Language : English, Spanish, And French

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✏Bipolar Disorder Book Summary : Bipolar disorder is a psychiatric disease that involves profound changes in mood accompanied by severe changes in feelings, thoughts and behaviors wherein emotions can move quickly from a deep depression to excessive excitement without apparent reason. In this book, the authors present current research in the study of the symptoms, management and risk factors of bipolar disorder. Topics include face emotion processing deficits in pediatric bipolar disorder; understanding bipolar disorder from clinical expression to therapeutic strategies; brain-derived neurotrophic factors and neurocognitive profiles in the psychosis spectrum; understanding lived experience and personal recovery in people with bipolar disorder; computerized self-management in bipolar disorder; prescription drug Memantine in the long-term prophylaxis of treatment-resistant bipolar mood disorders; P11 expression and PET as potential biomarkers for bipolar disorder; and neurocognitive impairment in bipolar disorder.

Novel Biomarkers For Bipolar Disorder Book PDF
✏Book Title : Novel Biomarkers for Bipolar Disorder
✏Author :
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1051333050
✏Available Language : English, Spanish, And French

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✏Novel Biomarkers for Bipolar Disorder Book Summary :

📒Studies On Psychiatric Disorders ✍ Anna Dietrich-Muszalska

Studies On Psychiatric Disorders Book PDF
✏Book Title : Studies on Psychiatric Disorders
✏Author : Anna Dietrich-Muszalska
✏Publisher : Springer
✏Release Date : 2015-01-02
✏Pages : 596
✏ISBN : 9781493904402
✏Available Language : English, Spanish, And French

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✏Studies on Psychiatric Disorders Book Summary : This authoritative volume reviews clinical, pathophysiological and therapeutic aspects of oxidative and nitrosative stress in different psychiatric disorders such as schizophrenia, bipolar disorder, autism, and attention deficit hyperactivity disorder (ADHD). Twenty-nine comprehensive chapters are divided into three distinct sections: clinical aspects, pathophysiological aspects, and therapeutic aspects. Together, these chapters present the environmental, genetic and neurodevelopmental factors in the generation of oxidative stress in psychiatric disorders, with particular emphasis on the biochemical changes associated with oxidative stress in dopaminergic and glutamate neurotransmission as well as mitochondrial dysfunction in the brain and peripheral cells. Through an investigation of glutamic acid decarboxylase (GAD) abnormalities in schizophrenia, the book provides a coherent framework to account for the impact of oxidative stress on pathological phenomena ranging from cellular to cognitive and clinical aspects. It describes biomarkers of oxidative damage, the role of oxidative stress in numerous abnormalities of biochemical pathways in the pathophysiology of schizophrenia, the development of new investigative techniques, specially neuroimaging, and studies of apoptotic pathways that seem to prove neurodegenerative and neurodevelopmental theories. Written by leading researchers in their fields, Studies on Psychiatric Disorders explores therapeutic approaches with aspects of various antioxidants, cryostimulation, and hyperbaric oxygen treatment in oxidative stress in neuropsychiatric diseases. The volume also discusses the role of antipsychotics in the treatment of schizophrenia on nitric oxide generation and biomarkers of oxidative stress together with the clinical symptomatology. Overall, it proposes that novel therapeutic strategies such as supplementation with antioxidants—in particular polyphenols, ω-3 fatty acids or combination of both—could be effective for long-term treatment of some neuropsychiatric disorders.

Bipolar Disorders New Insights For The Healthcare Professional 2013 Edition Book PDF
✏Book Title : Bipolar Disorders New Insights for the Healthcare Professional 2013 Edition
✏Author :
✏Publisher : ScholarlyEditions
✏Release Date : 2013-07-22
✏Pages : 435
✏ISBN : 9781481663489
✏Available Language : English, Spanish, And French

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✏Bipolar Disorders New Insights for the Healthcare Professional 2013 Edition Book Summary : Bipolar Disorders: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Bipolar Disorders: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bipolar Disorders: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biomarkers Of Neurological And Psychiatric Disease Book PDF
✏Book Title : Biomarkers of Neurological and Psychiatric Disease
✏Author : Sabine Bahn
✏Publisher : Academic Press
✏Release Date : 2011-11-23
✏Pages : 450
✏ISBN : 9780123877185
✏Available Language : English, Spanish, And French

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✏Biomarkers of Neurological and Psychiatric Disease Book Summary : Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Genetic Influences On Response To Drug Treatment For Major Psychiatric Disorders Book PDF
✏Book Title : Genetic Influences on Response to Drug Treatment for Major Psychiatric Disorders
✏Author : Janusz K. Rybakowski
✏Publisher : Springer
✏Release Date : 2016-02-04
✏Pages : 117
✏ISBN : 9783319270401
✏Available Language : English, Spanish, And French

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✏Genetic Influences on Response to Drug Treatment for Major Psychiatric Disorders Book Summary : Written by global experts, this book provides a modern comprehensive insight into the pharmacogenetics of treatment of major psychoses: schizophrenia, bipolar disorder and depression. The pharmacogenomics of three categories of the most important psychiatric drugs, antipsychotics, antidepressants and mood stabilizers, has been updated and reviewed. Some promising directions and perspectives for future research in pharmacogenetics in major psychoses are indicated. They are, among others, connected with the development of new methods in molecular genetics and with linking pharmacogenetics assessment with biomarkers, including neuroimaging ones. Finally, the attempts to use pharmacogenetics of antipsychotic, antidepressant and mood-stabilizing drugs in practice are presented. New pharmacogenetic tools may greatly contribute to introducing personalized medicine into psychiatric clinical practice.

Neuroscience Biomarkers And Biosignatures Book PDF
✏Book Title : Neuroscience Biomarkers and Biosignatures
✏Author : Institute of Medicine
✏Publisher : National Academies Press
✏Release Date : 2008-01-08
✏Pages : 128
✏ISBN : 0309178282
✏Available Language : English, Spanish, And French

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✏Neuroscience Biomarkers and Biosignatures Book Summary : Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.

Biomarkers For Psychiatric Disorders Book PDF
✏Book Title : Biomarkers for Psychiatric Disorders
✏Author : Chris Turck
✏Publisher : Springer Science & Business Media
✏Release Date : 2009-04-29
✏Pages : 538
✏ISBN : 0387792511
✏Available Language : English, Spanish, And French

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✏Biomarkers for Psychiatric Disorders Book Summary : Biomarkers hold immense promise for the early detection of disease. Unlike other disorders like diabetes and heart disease where a limited number of biological markers are at hand that allow the physician to come up with a reliable diagnosis, there are currently no such markers available for affective disorders. As in any other disease area a major goal is therefore the identification of early markers that can categorize subsets of subjects in a consistent manner. This will allow a more precise definition and categorization of affective disorders and in turn facilitate investigations of the pathogenesis of the diseases and enhance our ability for treatment. This edited volume will not only address the area of affective disorders but also other brain disorders that are neurological in nature, including Multiple Sclerosis and Alzheimer Disease.

Identifying Neuroimaging Based Markers For Distinguishing Brain Disorders Book PDF
✏Book Title : Identifying Neuroimaging Based Markers for Distinguishing Brain Disorders
✏Author : Yuhui Du
✏Publisher : Frontiers Media SA
✏Release Date : 2020-07-10
✏Pages :
✏ISBN : 9782889634040
✏Available Language : English, Spanish, And French

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✏Identifying Neuroimaging Based Markers for Distinguishing Brain Disorders Book Summary : There has been increasing interests in exploring biomarkers from brain images, aiming to have a better understanding and a more effective diagnosis of brain disorders such as schizophrenia, bipolar disorder, schizoaffective disorder, autism spectrum disorder, attention-deficit/hyperactivity disorder, Alzheimer’s disease and so on. Therefore, it is important to identify disease-specific changes for distinguishing healthy controls and patients with brain disorders as well as for differentiating patients with different disorders showing similar clinical symptoms. Biomarkers can be identified from different types of brain Imaging techniques including functional magnetic resonance imaging (fMRI), structural MRI, positron emission tomography (PET), electroencephalography (EEG), and magnetoencephalography (MEG) by using statistical analysis methods. Furthermore, based on measures from brain imaging techniques, machine learning techniques can help to classify or predict disease for individual subjects. In fact, fusion of features from multiple modalities may benefit the understanding of disease mechanism and improve the classification performance. This Research Topic further explores the functional or structural alterations in brain disorders.

An Investigation Of Cognitive Electrophysiological Biomarkers And Symptom Profile In Adhd And Bipolar Disorder Book PDF
✏Book Title : An Investigation of Cognitive electrophysiological Biomarkers and Symptom Profile in ADHD and Bipolar Disorder
✏Author : Viryanaga Kitsune
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1085198226
✏Available Language : English, Spanish, And French

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✏An Investigation of Cognitive electrophysiological Biomarkers and Symptom Profile in ADHD and Bipolar Disorder Book Summary :

Glutamate Related Biomarkers In Drug Development For Disorders Of The Nervous System Book PDF
✏Book Title : Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System
✏Author : Institute of Medicine
✏Publisher : National Academies Press
✏Release Date : 2011-08-05
✏Pages : 74
✏ISBN : 9780309212212
✏Available Language : English, Spanish, And French

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✏Glutamate Related Biomarkers in Drug Development for Disorders of the Nervous System Book Summary : Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

Peripheral Markers Of Immune Response In Major Psychiatric Disorders Where Are We Now And Where Do We Want To Be  Book PDF
✏Book Title : Peripheral Markers of Immune Response in Major Psychiatric Disorders Where Are We Now and Where Do We Want to Be
✏Author : Błażej Misiak
✏Publisher : Frontiers Media SA
✏Release Date : 2019-04-03
✏Pages : 115
✏ISBN : 9782889457977
✏Available Language : English, Spanish, And French

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✏Peripheral Markers of Immune Response in Major Psychiatric Disorders Where Are We Now and Where Do We Want to Be Book Summary : Major psychiatric disorders, including schizophrenia, bipolar disorder and major depression represent complex phenotypes with imprecise diagnostic boundaries. It has been found that these disorders can be characterized by a number of peripheral immune-inflammatory alterations, including, i.e. elevated levels of pro-inflammatory cytokines, increased levels of specific and non-specific antibodies or abnormal counts of lymphocyte subpopulations. Although it has been found that major psychiatric disorders share similar dysregulations of immune-inflammatory response, recent studies have also clearly demonstrated that some differences can be indicated. Interestingly, certain immune-inflammatory disturbances appear to be state markers, since they occur in acute relapse and normalize following pharmacological treatment, while the rest represents trait markers that remain stable regardless of treatment. It is also important to note that peripheral immune-inflammatory markers have been associated with psychopathological manifestation of major psychiatric disorders, response to treatment and long-term outcomes. However, it remains unclear what is the origin of peripheral inflammation in psychiatric disorders. To date, several mechanisms have been proposed, including the gut-brain axis dysregulation, infections in the neurodevelopmental period or immunogenetic factors. This eBook summarizes current evidence from studies investigating peripheral inflammation in schizophrenia, bipolar disorder, major depression and post-traumatic stress disorder as well as it provides future directions for the field.

Overdiagnosis In Psychiatry Book PDF
✏Book Title : Overdiagnosis in Psychiatry
✏Author : Joel Paris
✏Publisher : Oxford University Press, USA
✏Release Date : 2015
✏Pages : 208
✏ISBN : 9780199350643
✏Available Language : English, Spanish, And French

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✏Overdiagnosis in Psychiatry Book Summary : Dr. Joel Paris's Overdiagnosis in Psychiatry takes a much-needed look at the dangerous epidemic of unnecessary or incorrect treatments. The last 30 years of psychiatry have seen the development of a system of classification aimed at establishing greater scientific credibility. Unfortunately, the current categories are based entirely on signs and symptoms rather than on causes, which remain unknown. This has inevitably made diagnosis imprecise and uncertain. The result is that well-meaning professionals can have problems separating psychopathology from normality, can be unduly influenced by diagnostic fads, and can ultimately wind up prescribing treatments that do more harm than good. Paris examines prominent examples of overused diagnoses including major depressive disorder, ADHD, bipolar-II disorder, autism spectrum disorders, and PTSD.

📒Biomarkers ✍ Vishal S. Vaidya

Biomarkers Book PDF
✏Book Title : Biomarkers
✏Author : Vishal S. Vaidya
✏Publisher : John Wiley & Sons
✏Release Date : 2010-10-28
✏Pages : 632
✏ISBN : 0470918551
✏Available Language : English, Spanish, And French

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✏Biomarkers Book Summary : This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.

📒Clinical Staging In Psychiatry ✍ Patrick D. McGorry

Clinical Staging In Psychiatry Book PDF
✏Book Title : Clinical Staging in Psychiatry
✏Author : Patrick D. McGorry
✏Publisher : Cambridge University Press
✏Release Date : 2019-07-31
✏Pages : 300
✏ISBN : 9781108718844
✏Available Language : English, Spanish, And French

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✏Clinical Staging in Psychiatry Book Summary : Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.

📒Mental Health In The Workplace ✍ Michelle B. Riba

Mental Health In The Workplace Book PDF
✏Book Title : Mental Health in the Workplace
✏Author : Michelle B. Riba
✏Publisher : Springer
✏Release Date : 2019-02-13
✏Pages : 208
✏ISBN : 9783030042660
✏Available Language : English, Spanish, And French

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✏Mental Health in the Workplace Book Summary : This book offers a guide to better understanding models of workplace mental health, as well as best practices for mental health professionals, employee assistance groups, employers and employees alike. The cost of depression at the workplace is staggering, both in terms of absenteeism and productivity loss while at work, and in terms of human and family suffering. Depression is highly prevalent and affects employees’ concentration, decision-making skills and memory, contributing to accidents and quality issues. Analyses indicate that the returns on investment for workplace mental health programs are significant, with employers reporting lower productivity-related financial losses and less need staff turnover due to mental health conditions. The book also addresses substance use and misuse, and ways to address such problems.

📒Lecture Notes Psychiatry ✍ Gautam Gulati

Lecture Notes Psychiatry Book PDF
✏Book Title : Lecture Notes Psychiatry
✏Author : Gautam Gulati
✏Publisher : John Wiley & Sons
✏Release Date : 2013-10-21
✏Pages : 232
✏ISBN : 9781118378236
✏Available Language : English, Spanish, And French

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✏Lecture Notes Psychiatry Book Summary : Lecture Notes: Psychiatry provides a concise and accessible introduction to the fundamentals of Psychiatry, presenting the principles of Psychiatric examination followed by systematic coverage of the major psychiatric disorders, as well as covering management and treatment options. This eleventh edition has been revised to include recent developments in history-taking, psychotropic drugs and case presentations, as well as covering the practical elements of patient guidance and care. Key features include: • Clearly presented tables, figures and end-of-chapter ‘Key point’ summaries to aid revision • An emphasis on core management skills needed by Junior Doctors in both psychiatric and general hospital settings • Quick reference guides to help structure patient assessments on-the-go • MCQs and case studies in line with medical school and professional level psychiatry exams For those embarking on study or refreshing their knowledge of psychiatry, Lecture Notes: Psychiatry provides a step-by-step guide to both its wider and patient-centred practice.

📒Analysis Of Biomarker Data ✍ Stephen W. Looney

Analysis Of Biomarker Data Book PDF
✏Book Title : Analysis of Biomarker Data
✏Author : Stephen W. Looney
✏Publisher : John Wiley & Sons
✏Release Date : 2015-01-28
✏Pages : 424
✏ISBN : 9781118552452
✏Available Language : English, Spanish, And French

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✏Analysis of Biomarker Data Book Summary : A “how to” guide for applying statistical methods to biomarker data analysis Presenting a solid foundation for the statistical methods that are used to analyze biomarker data, Analysis of Biomarker Data: A Practical Guide features preferred techniques for biomarker validation. The authors provide descriptions of select elementary statistical methods that are traditionally used to analyze biomarker data with a focus on the proper application of each method, including necessary assumptions, software recommendations, and proper interpretation of computer output. In addition, the book discusses frequently encountered challenges in analyzing biomarker data and how to deal with them, methods for the quality assessment of biomarkers, and biomarker study designs. Covering a broad range of statistical methods that have been used to analyze biomarker data in published research studies, Analysis of Biomarker Data: A Practical Guide also features: A greater emphasis on the application of methods as opposed to the underlying statistical and mathematical theory The use of SAS®, R, and other software throughout to illustrate the presented calculations for each example Numerous exercises based on real-world data as well as solutions to the problems to aid in reader comprehension The principles of good research study design and the methods for assessing the quality of a newly proposed biomarker A companion website that includes a software appendix with multiple types of software and complete data sets from the book’s examples Analysis of Biomarker Data: A Practical Guide is an ideal upper-undergraduate and graduate-level textbook for courses in the biological or environmental sciences. An excellent reference for statisticians who routinely analyze and interpret biomarker data, the book is also useful for researchers who wish to perform their own analyses of biomarker data, such as toxicologists, pharmacologists, epidemiologists, environmental and clinical laboratory scientists, and other professionals in the health and environmental sciences.

Back To The Future On The Road Towards Precision Psychiatry Book PDF
✏Book Title : Back to the Future On the Road Towards Precision Psychiatry
✏Author : Brisa S. Fernandes
✏Publisher : Frontiers Media SA
✏Release Date : 2020-04-24
✏Pages :
✏ISBN : 9782889636617
✏Available Language : English, Spanish, And French

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✏Back to the Future On the Road Towards Precision Psychiatry Book Summary :