Big Mechanisms in Systems Biology

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  • Author : Bor-Sen Chen
  • Publisher : Academic Press
  • Pages : 878 pages
  • ISBN : 0128097078
  • Rating : /5 from reviews
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Download or Read online Big Mechanisms in Systems Biology full in PDF, ePub and kindle. this book written by Bor-Sen Chen and published by Academic Press which was released on 25 October 2016 with total page 878 pages. We cannot guarantee that Big Mechanisms in Systems Biology book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system immunity, regulation, infection, aging, evolution, and carcinogenesis, which are complicated biological systems with inconsistent findings in existing resources. These inconsistencies may reflect the underlying biology time-varying systems and signal transduction events that are often context-dependent, which raises a significant problem for mechanistic modeling since it is not clear which genes/proteins to include in models or experimental measurements. The book is a valuable resource for bioinformaticians and members of several areas of the biomedical field who are interested in an in-depth understanding on how to process and apply great amounts of biological data to improve research. Written in a didactic manner in order to explain how to investigate Big Mechanisms by big data mining and system identification Provides more than 140 diagrams to illustrate Big Mechanism in systems biology Presents worked examples in each chapter

Big Mechanisms in Systems Biology

Big Mechanisms in Systems Biology
  • Author : Bor-Sen Chen,Cheng-Wei Li
  • Publisher : Academic Press
  • Release : 25 October 2016
GET THIS BOOK Big Mechanisms in Systems Biology

Big Mechanisms in Systems Biology: Big Data Mining, Network Modeling, and Genome-Wide Data Identification explains big mechanisms of systems biology by system identification and big data mining methods using models of biological systems. Systems biology is currently undergoing revolutionary changes in response to the integration of powerful technologies. Faced with a large volume of available literature, complicated mechanisms, small prior knowledge, few classes on the topics, and causal and mechanistic language, this is an ideal resource. This book addresses system

Systems Biology

Systems Biology
  • Author : Dimitrios Vlachakis
  • Publisher : BoD – Books on Demand
  • Release : 19 June 2019
GET THIS BOOK Systems Biology

Systems biology is the inevitable outcome of long years of knowledge acquisition and data accumulation. The aim of systems biology is to integrate in a seamless way all existing knowledge in interconnected disciplines, stretching from modern biomedical research to physics, chemistry, and mathematics. The main integration tool of such complex biomedical systems is via computational and mathematical modeling. In this direction, a series of state-of-the-art computer science techniques are used, namely, data mining and fusion, machine learning, and deep learning

Molecular Mechanisms of Autonomy in Biological Systems

Molecular Mechanisms of Autonomy in Biological Systems
  • Author : Tara Karimi
  • Publisher : Springer
  • Release : 28 July 2018
GET THIS BOOK Molecular Mechanisms of Autonomy in Biological Systems

This book presents a novel molecular description for understanding the regulatory mechanisms behind the autonomy and self-organization in biological systems. Chapters focus on defining and explaining the regulatory molecular mechanisms behind different aspects of autonomy and self-organization in the sense of autonomous coding, data processing, structure (mass) formation and energy production in a biological system. Subsequent chapters discuss the cross-talk among mechanisms of energy, and mass and information, transformation in biological systems. Other chapters focus on applications regarding therapeutic approaches

Philosophy of Systems Biology

Philosophy of Systems Biology
  • Author : Sara Green
  • Publisher : Springer
  • Release : 15 December 2016
GET THIS BOOK Philosophy of Systems Biology

The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the

Systems Biology of Cancer

Systems Biology of Cancer
  • Author : Sam Thiagalingam
  • Publisher : Cambridge University Press
  • Release : 09 April 2015
GET THIS BOOK Systems Biology of Cancer

With over two hundred types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community: exploiting systems biology to generate

Metabolome Analyses

Metabolome Analyses
  • Author : Seetharaman Vaidyanathan,George G. Harrigan,Royston Goodacre
  • Publisher : Springer Science & Business Media
  • Release : 28 April 2005
GET THIS BOOK Metabolome Analyses

Metabolome analysis is now recognized as a crucial component of functional genomic and systems biology investigations. Innovative approaches to the study of metabolic regulation in microbial, plant and animal systems are increasingly facilitating the emergence of systems approaches in biology. This book highlights analytical and bioinformatics strategies now available for investigating metabolic networks in microbial, plant and animal systems. The contributing authors are world leaders in this field and they present an unambiguous case for pursuing metabolome analysis as a

Case Studies in Systems Biology

Case Studies in Systems Biology
  • Author : Pavel Kraikivski
  • Publisher : Springer
  • Release : 27 October 2021
GET THIS BOOK Case Studies in Systems Biology

This book provides case studies that can be used in Systems Biology related classes. Each case study has the same structure which answers the following questions: What is the biological problem and why is it interesting? What are the relevant details with regard to cell physiology and molecular mechanisms? How are the details put together into a mathematical model? How is the model analyzed and simulated? What are the results of the model? How do they compare to the known

High Confidence Network Predictions from Big Biological Data

High Confidence Network Predictions from Big Biological Data
  • Author : Rasmus Magnusson
  • Publisher : Linköping University Electronic Press
  • Release : 04 May 2020
GET THIS BOOK High Confidence Network Predictions from Big Biological Data

Biology functions in a most intriguing fashion, with human cells being regulated by multiplex networks of proteins and their dependent systems that control everything from proliferation to cell death. Notably, there are cases when these networks fail to function properly. In some diseases there are multiple small perturbations that push the otherwise healthy cells into a state of malfunction. These maladies are referred to as complex diseases, and include common disorders such as allergy, diabetes type II, and multiple sclerosis,

Systems Cancer Biology

Systems Cancer Biology
  • Author : Bor-Sen Chen
  • Publisher : Cambridge Scholars Publishing
  • Release : 13 July 2021
GET THIS BOOK Systems Cancer Biology

Cancer is a complex and heterogeneous (systematic) disease that exhibits high levels of robustness against various therapeutic interventions. Due to the complex, heterogeneous, and evolving nature of cancer, it is essential for a system-oriented view to be adopted in order to understand the pathogenic mechanism of cancer which will eventually lead to the drug discovery and treatment of patients. This book not only provides new insights from system modeling and large scale experimental data, but also will allow the reader

Leveraging Biomedical and Healthcare Data

Leveraging Biomedical and Healthcare Data
  • Author : Firas Kobeissy,Kevin Wang,Fadi A. Zaraket,Ali Alawieh
  • Publisher : Academic Press
  • Release : 23 November 2018
GET THIS BOOK Leveraging Biomedical and Healthcare Data

Leveraging Biomedical and Healthcare Data: Semantics, Analytics and Knowledge provides an overview of the approaches used in semantic systems biology, introduces novel areas of its application, and describes step-wise protocols for transforming heterogeneous data into useful knowledge that can influence healthcare and biomedical research. Given the astronomical increase in the number of published reports, papers, and datasets over the last few decades, the ability to curate this data has become a new field of biomedical and healthcare research. This book

Systems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology
  • Author : Bor-Sen Chen
  • Publisher : Academic Press
  • Release : 15 March 2021
GET THIS BOOK Systems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate the development procedure to understand the results of the systems immunology and infection microbiology. The results are not only remarkable, but also revolutionary in immunology and infection microbiology and can be also applied to systems drug design in infectious diseases.The book is divided into six parts. The first one discusses systems immunology; the second, systems infection microbiology; the third, systematic inflammation

LabStudio

LabStudio
  • Author : Jenny E. Sabin,Peter Lloyd Jones
  • Publisher : Unknown
  • Release : 01 May 2017
GET THIS BOOK LabStudio

LabStudio: Design Research between Architecture and Biology introduces the concept of the research design laboratory in which funded research and trans-disciplinary participants achieve radical advances in science, design, and applied architectural practice. The book demonstrates to natural scientists and architects alike new approaches to more traditional design studio and hypothesis-led research that are complementary, iterative, experimental, and reciprocal. These originate from 3-D spatial biology and generative design in architecture, creating philosophies and practices that are high-risk, non-linear, and design-driven for

Computational Methods in Systems Biology

Computational Methods in Systems Biology
  • Author : Jérôme Feret,Heinz Koeppl
  • Publisher : Springer
  • Release : 06 October 2017
GET THIS BOOK Computational Methods in Systems Biology

This book constitutes the refereed proceedings of the 15th International Conference on Computational Methods in Systems Biology, CMSB 2017, held in Darmstadt, Germany, in September 2017. The 15 full papers, 4 tool papers and 4 posters presented together with 1 invited talk were carefully reviewed and selected from 41 regular paper submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verication, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from

Systems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology
  • Author : Bor-Sen Chen
  • Publisher : Academic Press
  • Release : 16 March 2021
GET THIS BOOK Systems Immunology and Infection Microbiology

Systems Immunology and Infection Microbiology provides a large amount of biological system models, diagrams and flowcharts to illustrate development procedures and help users understand the results of systems immunology and infection microbiology. Chapters discuss systems immunology, systems infection microbiology, systematic inflammation and immune responses in restoration and regeneration process, systems' innate and adaptive immunity in infection process, systematic genetic and epigenetic pathogenic/defensive mechanism during bacterial infection on human cells is introduced, and the systematic genetic and epigenetic pathogenic/defensive