Rigor and Reproducibility in Genetics and Genomics

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  • Author : Anonim
  • Publisher : Academic Press
  • Pages : 472 pages
  • ISBN : 0128172193
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Rigor and Reproducibility in Genetics and Genomics

Download or Read online Rigor and Reproducibility in Genetics and Genomics full in PDF, ePub and kindle. this book written by Anonim and published by Academic Press which was released on 01 July 2021 with total page 472 pages. We cannot guarantee that Rigor and Reproducibility in Genetics and Genomics book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists. Provides practical approaches and step-by-step protocols to strengthen genetic and genomic research conducted in the lab or classroom Through illustrative case studies and training exercises, discusses common pitfalls and solutions for genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing, among other genetic and genomic approaches Specifically examines best practices for microarray analysis, DNA-seq, RNA-seq, gene expression validation, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis

Rigor and Reproducibility in Genetics and Genomics

Rigor and Reproducibility in Genetics and Genomics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 July 2021
GET THIS BOOK Rigor and Reproducibility in Genetics and Genomics

Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies

Clinical Genome Sequencing

Clinical Genome Sequencing
  • Author : Aad Tibben,Barbara B. Biesecker
  • Publisher : Academic Press
  • Release : 30 March 2019
GET THIS BOOK Clinical Genome Sequencing

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing,

Understanding Disparities in Access to Genomic Medicine

Understanding Disparities in Access to Genomic Medicine
  • Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Roundtable on Genomics and Precision Health
  • Publisher : National Academies Press
  • Release : 28 January 2019
GET THIS BOOK Understanding Disparities in Access to Genomic Medicine

Genomic medicine is defined as the routine use of genomic information about an individual as part of his or her clinical care as well as the health outcomes and policy implications of that clinical use. It is one approach that has the potential to improve the quality of health care by allowing practitioners to tailor prevention, diagnostic, and treatment strategies to individual patients. In recent years, research breakthroughs, technological advances, and the decreasing cost of DNA sequencing have led to

UNDERSTANDING DISPARITIES IN ACCESS TO GENOMIC MEDICINE

UNDERSTANDING DISPARITIES IN ACCESS TO GENOMIC MEDICINE
  • Author : Anonim
  • Publisher : Unknown
  • Release : 18 January 2022
GET THIS BOOK UNDERSTANDING DISPARITIES IN ACCESS TO GENOMIC MEDICINE

"Genomic medicine is defined as the routine use of genomic information about an individual as part of his or her clinical care as well as the health outcomes and policy implications of that clinical use. It is one approach that has the potential to improve the quality of health care by allowing practitioners to tailor prevention, diagnostic, and treatment strategies to individual patients. In recent years, research breakthroughs, technological advances, and the decreasing cost of DNA sequencing have led to

Applications of Genetic and Genomic Research in Cereals

Applications of Genetic and Genomic Research in Cereals
  • Author : Thomas Miedaner,Viktor Korzun
  • Publisher : Woodhead Publishing
  • Release : 19 November 2018
GET THIS BOOK Applications of Genetic and Genomic Research in Cereals

Applications of Genetic and Genomic Research in Cereals covers new techniques for practical breeding, also discussing genetic and genomic approaches for improving special traits. Additional sections cover drought tolerance, biotic stress, biomass production, the impact of modern techniques on practical breeding, hybrid breeding, genetic diversity, and genomic selection. Written by an international team of top academics and edited by an expert in the field, this book will be of value to academics working in the agricultural sciences and essential reading

Genomics Enabled Learning Health Care Systems

Genomics Enabled Learning Health Care Systems
  • Author : Institute of Medicine,Board on Health Sciences Policy,Roundtable on Translating Genomic-Based Research for Health
  • Publisher : National Academies Press
  • Release : 08 July 2015
GET THIS BOOK Genomics Enabled Learning Health Care Systems

The inclusion of genomic data in a knowledge-generating health care system infrastructure is one promising way to harness the full potential of that information to provide better patient care. In such a system, clinical practice and research influence each other with the goal of improving the efficiency and effectiveness of disease prevention, diagnosis, and treatment. To examine pragmatic approaches to incorporating genomics in learning health care systems, the Institute of Medicine Roundtable on Translating Genomic-Based Research for Health hosted a

Clinical DNA Variant Interpretation

Clinical DNA Variant Interpretation
  • Author : Conxi Lázaro,Jordan Lerner-Ellis,Amanda Spurdle
  • Publisher : Academic Press
  • Release : 27 February 2021
GET THIS BOOK Clinical DNA Variant Interpretation

Clinical DNA Variant Interpretation: Theory and Practice, a new volume in the Translational and Applied Genomics series, covers foundational aspects, modes of analysis, technology, disease and disorder specific case studies, and clinical integration. This book provides a deep theoretical background, as well as applied case studies and methodology, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes. Practical chapters discuss genomic variant interpretation, terminology and nomenclature, international consensus guidelines, population allele frequency,

Responsible Genomic Data Sharing

Responsible Genomic Data Sharing
  • Author : Xiaoqian Jiang,Haixu Tang
  • Publisher : Academic Press
  • Release : 14 March 2020
GET THIS BOOK Responsible Genomic Data Sharing

Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia. Addresses privacy preserving technologies and

The Least Cost Path From Landscape Genetics to Landscape Genomics

The Least Cost Path From Landscape Genetics to Landscape Genomics
  • Author : Samuel A. Cushman,Andrew J. Shirk,Glenn T. Howe,Melanie A. Murphy,Rodney J. Dyer,Stéphane Joost
  • Publisher : Frontiers Media SA
  • Release : 03 August 2018
GET THIS BOOK The Least Cost Path From Landscape Genetics to Landscape Genomics

Ecosystems are the stage on which the play of evolution is acted, and ecosystems are complex, spatially structured and temporally varying. The purpose of this Research Topic is to explore critical challenges and opportunities for the transition from landscape genetics to landscape genomics. Landscape genetics has focused on the spatial analysis of small genetic datasets, typically comprised of less than 20 microsatellite markers, taken from clusters of individuals in putative populations or distributed individuals across landscapes. The recent emergence of large

Practical Genomics for Clinical Ophthalmology

Practical Genomics for Clinical Ophthalmology
  • Author : Jane Ashworth,Graeme Black,Bart P. Leroy,Panagiotis I. Sergouniotis
  • Publisher : Elsevier
  • Release : 31 January 2022
GET THIS BOOK Practical Genomics for Clinical Ophthalmology

Practical Genomics for Clinical Ophthalmology provides in-depth coverage of the clinical applications of genomics in eye disease, with a key emphasis on case-study based instruction in patient care and genetic counseling aspects, genetic and genomic diagnostics, and treatment pathways. The book presents the latest information on genetic and genomic test results, best practices for delivery of results to patients and families, and ongoing research into therapeutics, with specific chapters covering non-syndromic inherited retinal disease, syndromic IRD, vitreoretinopathies, lens abnormalities, corneal

Latin American Perspectives on Scientific Research

Latin American Perspectives on Scientific Research
  • Author : Fernando Lolas,Eduardo Rodriguez
  • Publisher : Cambridge Scholars Publishing
  • Release : 28 October 2019
GET THIS BOOK Latin American Perspectives on Scientific Research

This collection of papers presents case studies and reflections on research bioethics from the standpoint of two Latin American academics involved in the teaching and dissemination of good practices and essential information on bioethics and various related topics. While limited in scope to a few key issues, the text may be read as an inspiration to comparative analyses of research practices involving human subjects and as an example of the reception of fundamental ideas on science and technology adopted in

From Biotechnology to Genomes

From Biotechnology to Genomes
  • Author : Ph Goujon
  • Publisher : World Scientific
  • Release : 18 January 2022
GET THIS BOOK From Biotechnology to Genomes

Aimed at scientists and non-specialised readers alike, this book retraces the source of national and international biotechnology programmes by examining the origins of biotechnology and its political and economic interpretation by large nations. With a foreword by Andr‚ Goffeau, who initiated the European Yeast Genome Project, the book describes the achievements of the first genetic and physical maps, as well as the political and scientific genesis of the American Human Genome Project. Following these advances, the author discusses the European

Computational Methods in Genome Research

Computational Methods in Genome Research
  • Author : International Symposium on Computational Methods in Genome Research (1992 : Heidelberg)
  • Publisher : Springer Science & Business Media
  • Release : 18 January 1994
GET THIS BOOK Computational Methods in Genome Research

Can computational science keep up with evolving technology for genome mapping and sequencing?; Informatics and experiments for the human genome project; Data management tools for scientific applications: framework, status, and genomic applications; The ACEDB genome database; The integrated genomic database (IGD); Genetic mapping, an overview; Representing genomic maps in a relational database; Livermore's pragmatic approach to integrated mapping for chromosome 19; Searching protein sequence databases - is optimal best?; Algorithmic advances for searching biosequence databases; Pattern recognition in genomic and protein

Precision Medicine in Pediatric Health

Precision Medicine in Pediatric Health
  • Author : Olaf Bodamer
  • Publisher : Academic Press
  • Release : 01 March 2020
GET THIS BOOK Precision Medicine in Pediatric Health

Precision Medicine in Pediatric Health is an invaluable resource on state-of-the-art tools, technologies and social and ethical issues involved in fully realizing precision medicine in new pediatric research and healthcare. The book adopts a holistic approach that is grounded in key learning points and practical case studies of interest to interdisciplinary teams of researchers and clinicians working in pediatrics. Chapters provide a thorough introduction to basic principles of precision medicine, its growing role in research and clinical care, relevant technologies