Ascaris The Neglected Parasite

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  • Author : Celia Holland
  • Publisher : Newnes
  • Pages : 460 pages
  • ISBN : 012397285X
  • Rating : /5 from reviews
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Download or Read online Ascaris The Neglected Parasite full in PDF, ePub and kindle. this book written by Celia Holland and published by Newnes which was released on 09 May 2013 with total page 460 pages. We cannot guarantee that Ascaris The Neglected Parasite book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines. Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites. Brings together a wide range of topics and approaches and recent, comprehensive and progressive research concerning the neglected parasite Ascaris Provides a blueprint of how a single parasite entity can stimulate interest in basic biology, clinical science, veterinary science, public health and epidemiology Presents a wealth of new insights given that a book on this parasite has not been published for over 20 years 16 chapters from a range of top authors from around the world

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Celia Holland
  • Publisher : Newnes
  • Release : 09 May 2013
GET THIS BOOK Ascaris The Neglected Parasite

This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines. Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans,

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Simon J. Brooker,Rachel L. Pullan
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
GET THIS BOOK Ascaris The Neglected Parasite

Ascariasis is a neglected tropical disease (NTD) affecting 763 million people worldwide, with nutritional and developmental consequences of chronic childhood infection and severe clinical disease occurring in heavy infections. Reliably estimating the extent of the problem of Ascaris lumbricoides and ascariasis is difficult because of inaccuracies in parasitological diagnosis, the non-specificity of clinical signs, and a paucity of reliable and accurate data. As a consequence, estimating the global distribution and disease burden has been based on informed approximations, using the best

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Martin Walker,Andrew Hall,María-Gloria Basáñez
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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In the context of the current unprecedented momentum and commitment to control neglected tropical diseases, and the increased advocacy of anthelmintic mass drug administration (MDA), there are renewed calls for research and development into the epidemiology and population biology of helmintic parasites to be embedded at the core of intervention strategies. This review of the epidemiology of Ascaris lumbricoides – one of the three neglected soil-transmitted helminth infections of greatest public health importance – includes discussion on diagnostic methods and their limitations;

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Johnny Vlaminck,Peter Geldhof
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Roundworms are the most prevalent parasite of swine in the world today. Their presence on a pig farm can have detrimental effects on farm profitability due to their impact on growth rate, feed conversion, and general health of the produced pigs. For farmers, it is therefore essential to be aware of the “worm status” of their herd in order to make informed decisions on how to control this disease on their farm. This chapter concentrates on the diverse aspects involved

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Philip J. Cooper,Camila A. Figuieredo
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Natural infections with Ascaris lumbricoides and A. suum of pigs and humans, respectively, have a worldwide distribution. Ascaris infections induce strong Th2 responses in the host that appear to be central to the development of protective immunity. Th2 responses may be modulated actively through a complex host–parasite interaction that allows the parasite to survive but also limits severe Th2-mediated pathology in the host. The increased production of IL-10 by regulatory cell populations may have a key role in

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Stig Milan Thamsborg,Peter Nejsum,Helena Mejer
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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The roundworm Ascaris suum is a highly prevalent intestinal parasite of pigs worldwide, and the infection may have low to moderate pathogenic effects on health and productivity. Besides these direct effects, there may be indirect effects on enhanced susceptibility or pathogenicity to bacterial or viral infections, related to the migratory and immune-modulatory capacity of A. suum. Losses due to ascariasis in pigs can thus be summarized as (1) farm economic losses due to clinical effects (although limited), reduced growth and feed

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Celia V. Holland,Jerzy M. Behnke,Christina Dold
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Larval ascariasis is much less well understood than adult worm infection. Part of the explanation for this is the difficulty in assessing the impact of larval infections in human subjects. In contrast, adult worms can be counted after post-chemotherapeutic expulsion or, additionally, eggs voided in host feces can be quantified as an indirect measure of infection intensity. Furthermore, respiratory and hepatic disease, which may be associated with transient passage of larvae through these organs, can be either non-specific or cryptic,

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Antony O.W. Stretton,Aaron G. Maule
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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The structural simplicity of nematode nervous systems has provided a useful resource for studies on basic neurobiology. Two species have underpinned basic neuroscience research in phylum Nematoda, the free-living nematode Caenorhabditis elegans and the pig parasitic nematode Ascaris suum due to their genetic tractability and large size, respectively. The fact that most of the chemotherapeutic targets for the treatment of roundworm parasite infections of animals and man associate with neuromuscular function means that nematode neurobiology research resonates beyond discovery biology

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : T. Déirdre Hollingsworth,James E. Truscott,Roy M. Anderson
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Mathematical models are playing an increasing role in the design and optimization of control programs for many infectious diseases. In the case of Ascaris lumbricoides, there is a long history of models to understand the biology and epidemiology and to design control programs. We outline the key insights which models have given on the dynamics of Ascaris transmission, describe the model structures and discuss how current and future models are informing the design of control programs in the era of

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Luis Caraballo
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Ascaris lumbricoides infects humans causing ascariasis. The immune response to this helminth shares mechanisms with the allergic reaction and may influence the natural history of allergy phenotypes. The high levels of total IgE associated with ascariasis restrict the use of this test in the diagnosis of allergy. Also, the immunological cross-reactivity between Ascaris and domestic mites has implications in the diagnosis of both allergy and ascariasis. Depending on the infection intensity and host’s susceptibility, in countries where helminthiases are

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Francisca Abanyie,Tracey J. Lamb
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Co-infection with other pathogens is a common occurrence in Ascaris-infected individuals and it is generally accepted that co-infection is not inconsequential to the host. Interactions in the immune responses generated to each pathogen can, in certain situations, alter the pathogenesis and progression of a co-infecting pathogen in an Ascaris-infected host. There is also some evidence that co-infection can impact on the transmission potential of co-infecting pathogens in an Ascaris-infected host. In this chapter we review some of the general principles

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Martha Betson,Peter Nejsum,J. Russell Stothard
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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To better understand the epidemiology of ascariasis, molecular genetic methods have been applied to differentiate between worms found infecting people and pigs, and other occasional hosts. Owing to difficulties in applying species concepts, the longstanding debate of the distinction(s) between Ascaris lumbricoides and Ascaris suum continues. From an applied perspective, however, molecular markers help to “tag” and “track” worms during their transmission cycle(s), providing new insights into host range, as well as methods for assessing parasite population dynamics

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Antonio Montresor,Albis Francesco Gabrielli,Lorenzo Savioli
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Experiences from Japan and Korea demonstrated that when a country is developing economically, the periodic administration of anthelmintic (preventive chemotherapy) drastically reduces soil-transmitted helminthiasis (STH) and these advances are then maintained by increasing sanitation standards; both countries eliminated the morbidity due to STH in less than a decade. The situation is more complex in countries with slow economic development in which preventive chemotherapy should be maintained over a longer period of time in order to reduce morbidity due to STH.

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Malcolm W. Kennedy
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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In comparison with other helminths that afflict humans on a global scale, Ascaris lumbricoides and ascariasis are relatively under-researched in terms of the proteins and other products to which the parasites expose their hosts. The reputation of the parasite as a source of potent allergens, and the recognition that immune hypersensitivity in the lung caused by migrating larvae is a significant problem, has served to focus attention on immune responses to Ascaris. Research has increasingly focused on the parasite’s

Ascaris The Neglected Parasite

Ascaris  The Neglected Parasite
  • Author : Sarah Williams-Blangero,Mona H. Fenstad,Satish Kumar,John Blangero
  • Publisher : Elsevier Inc. Chapters
  • Release : 09 May 2013
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Ascaris infections remain major global public health problems despite the wide availability of cheap, effective anthelminthic drugs. An improved understanding of host susceptibility to Ascaris infection may suggest new approaches for targeting available drugs more effectively, or may suggest novel targets for drug development efforts. This chapter explores our current understanding of the underlying genetic architecture of susceptibility to Ascaris infection. The past and potential future uses of different types of genetic approaches, from quantitative genetic studies of heritability, to