Annotating New Genes

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  • Author : Shizuka Uchida
  • Publisher : Elsevier
  • Pages : 196 pages
  • ISBN : 1908818123
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Annotating New Genes

Download or Read online Annotating New Genes full in PDF, ePub and kindle. this book written by Shizuka Uchida and published by Elsevier which was released on 06 August 2012 with total page 196 pages. We cannot guarantee that Annotating New Genes book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. Focuses not only on screening but also on biological validations Provides details of databases and software (web interface) products for biologists with minimal computation skills Offers a step-by-step outline of the procedure involved

Annotating New Genes

Annotating New Genes
  • Author : Shizuka Uchida
  • Publisher : Elsevier
  • Release : 06 August 2012
GET THIS BOOK Annotating New Genes

In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases

Development of New Tools and Pipelines for Plant Bioinformatics Applications

Development of New Tools and Pipelines for Plant Bioinformatics Applications
  • Author : Omar M. Darwish
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Development of New Tools and Pipelines for Plant Bioinformatics Applications

Blueberry is an economically and nutritionally important small fruit crop, native to North America. As with many crops, extreme low temperature can affect blueberry crop yield negatively and cause major losses to growers. For this reason, blueberry breeding programs have focused on developing improved cultivars with broader climatic adaptation. To help achieve this goal, the blueberry genomic database (BBGD454) was developed to provide the research community with valuable resources to identify genes that play an important role in flower bud

IMG ER

IMG ER
  • Author : Anonim
  • Publisher : Unknown
  • Release : 26 October 2021
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A rapidly increasing number of microbial genomes are sequenced by organizations worldwide and are eventually included into various public genome data resources. The quality of the annotations depends largely on the original dataset providers, with erroneous or incomplete annotations often carried over into the public resources and difficult to correct. We have developed an Expert Review (ER) version of the Integrated Microbial Genomes (IMG) system, with the goal of supporting systematic and efficient revision of microbial genome annotations. IMG ER

An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome

An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome
  • Author : Matthew Morritt Hindle
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome

Given the ever increasing quantity of sequence data, functional annotation of new gene sequences persists as being a significant challenge for bioinformatics. This is a particular problem for transcriptomics studies in crop plants where large genomes and evolutionarily distant model organisms, means that identifying the function of a given gene used on a microarray, is often a non-trivial task. Information pertinent to gene annotations is spread across technically and semantically heterogeneous biological databases. Combining and exploiting these data in a

Modern Genome Annotation

Modern Genome Annotation
  • Author : D. Frishman,Alfonso Valencia
  • Publisher : Springer Science & Business Media
  • Release : 02 October 2009
GET THIS BOOK Modern Genome Annotation

An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry. Included is an overview of bioinformatics, the full spectrum of genome annotation approaches including; genome analysis and gene prediction, gene regulation analysis and expression, genome variation and QTL analysis, large scale

Genome Annotation

Genome Annotation
  • Author : Jung Soh,Paul M.K. Gordon,Christoph W. Sensen
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOK Genome Annotation

The success of individualized medicine, advanced crops, and new and sustainable energy sources requires thoroughly annotated genomic information and the integration of this information into a coherent model. A thorough overview of this field, Genome Annotation explores automated genome analysis and annotation from its origins to the challenges of next-generation sequencing data analysis. The book initially takes you through the last 16 years since the sequencing of the first complete microbial genome. It explains how current analysis strategies were developed, including

Automatic Annotation of Multigene Families the Case of Peroxidases

Automatic Annotation of Multigene Families  the Case of Peroxidases
  • Author : Nizar Fawal
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Automatic Annotation of Multigene Families the Case of Peroxidases

Gene families are groups of homologous genes with a common ancestor that are likely to have highly similar sequences and functions. In our team, we are mainly interested in one of these families, the peroxidase superfamily. Peroxidases are universal enzymes present in all organisms where they typically catalyze the reduction of peroxides, such as hydrogen peroxide and the oxidation of a variety of organic and inorganic compounds. However, with the continually reducing cost and time of genome sequencing, expert manual

A Case Study of Oryza sativa Annotation of Plant Genome

A Case Study of Oryza sativa  Annotation of Plant Genome
  • Author : IDSAsr Study
  • Publisher : GRIN Verlag
  • Release : 29 September 2020
GET THIS BOOK A Case Study of Oryza sativa Annotation of Plant Genome

Scientific Study from the year 2020 in the subject Computer Science - Bioinformatics, , language: English, abstract: Using Insilco analysis mode, the present study is an attempt to examine various characteristics conformation of senescence causing gene in rice. The two gene chosen were HCP and RR because, the interaction in between these two led to the onset of senescence in rice. Two gene that is HCP (Histidine-containing phosphor transfer protein 1) and RR (Two-component response regulator) are responsible for attaining the stage of

Genome Annotation and Finding Repetitive DNA Elements

Genome Annotation and Finding Repetitive DNA Elements
  • Author : Renu Rawat
  • Publisher : Unknown
  • Release : 03 June 2014
GET THIS BOOK Genome Annotation and Finding Repetitive DNA Elements

Bachelor Thesis from the year 2014 in the subject Computer Science - Bioinformatics, grade: 8.26, Lovely Professional University, course: b.tech honors biotechnology, language: English, abstract: As the number of genomes sequenced is increasing at high rate, there is a need of gene prediction method which is quick, reliable, inexpensive. In such conditions, the computations tool will serve as an alternative to wet lab methods. The confidence level of annotation by the tool can be enhanced by preparing exhaustive training data sets.

Reannotation and Extended Community Resources for the Genome of the Non seed Plant Physcomitrella Patens Provide Insights Into the Evolution of Plant Gene Structures and Functions

Reannotation and Extended Community Resources for the Genome of the Non seed Plant Physcomitrella Patens Provide Insights Into the Evolution of Plant Gene Structures and Functions
  • Author : Andreas D. Zimmer,Daniel Lang,Karol Buchta,Stefan A. Rensing,Ralf Reski
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Reannotation and Extended Community Resources for the Genome of the Non seed Plant Physcomitrella Patens Provide Insights Into the Evolution of Plant Gene Structures and Functions

Transcription of Human specific Duplicate Genes

Transcription of Human specific Duplicate Genes
  • Author : Max L. Dougherty
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Transcription of Human specific Duplicate Genes

In this work, I set out to characterize new genes contained specifically within the human genome but absent from any other, including our closest evolutionary cousins. Our interest in these genes is twofold: First, gene duplication is a fundamental process by which evolutionary innovations at the organismal level arise; and second, we believe that variation in these new genes is an important and unappreciated source of phenotypic differences between individuals, both normal and pathogenic. The ability to interpret observed variation

Gene Annotation and Disease Gene Prediction from an Integrated Functional Linkage Gene Network

Gene Annotation and Disease Gene Prediction from an Integrated Functional Linkage Gene Network
  • Author : Bolan Linghu
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Gene Annotation and Disease Gene Prediction from an Integrated Functional Linkage Gene Network

Abstract: In the postgenomic era, it remains a challenging task to understand the cellular functions of genes and how the dysfunction of a gene relates to a disease. Since genes work cooperatively for particular cellular tasks, a functional linkage network (FLN) can be used for function-related studies. In this network, the nodes represent genes and the weighted edges represent the degree of their functional association. Here I explore the FLN construction, FLN-based gene-function prediction, and FLN-based new-disease-gene prediction. In the

Database Annotation in Molecular Biology

Database Annotation in Molecular Biology
  • Author : Arthur M. Lesk
  • Publisher : John Wiley & Sons
  • Release : 01 September 2005
GET THIS BOOK Database Annotation in Molecular Biology

Two factors dominate current molecular biology: the amount of raw data is increasing very rapidly and successful applications in biomedical research require carefully curated and annotated databases. The quality of the experimental data -- especially nucleic acid sequences -- is satisfactory; however, annotations depend on features inferred from the data rather than measured directly, for instance the identification of genes in genome sequences. It is essential that these inferences are as accurate as possible and this requires human intervention. With

Comparative Annotation Toolkit CAT Simultaneous Clade and Personal Genome Annotation

Comparative Annotation Toolkit  CAT    Simultaneous Clade and Personal Genome Annotation
  • Author : Ian Fiddes
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Comparative Annotation Toolkit CAT Simultaneous Clade and Personal Genome Annotation

The recent introductions of low-cost, long-read and read-cloud sequencing technologies coupled with intense efforts to develop efficient algorithms have made affordable, high-quality de-novo sequence assembly a realistic proposition. The result is an explosion of new, ultra contiguous genome assemblies. To compare these genomes we need robust methods for genome annotation. I describe the fully open source Comparative Annotation Toolkit (CAT), which provides a flexible way to simultaneously annotate entire clades and identify orthology relationships. I show that CAT can be

Genesmith

Genesmith
  • Author : Ravi Dandekar
  • Publisher : Unknown
  • Release : 26 October 2021
GET THIS BOOK Genesmith

Modern gene prediction, otherwise known as ab initio gene annotation, has yet to progress to a level of accuracy where it can replace the more costly process of manual curation through laboratory experiments. Gene annotation software utilizes machine learning approaches to model genes using Hidden Markov Models (HMMs) in order to accurately predict the location and structure of genes in a given genome. To gain a more cohesive understanding of which components can be improved in gene prediction algorithms, we