An Innovative Approach to Understanding and Treating Cancer Targeting pH

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  • Author : Tomas Koltai
  • Publisher : Academic Press
  • Pages : 574 pages
  • ISBN : 0128190604
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>An Innovative Approach to Understanding and Treating Cancer Targeting pH

Download or Read online An Innovative Approach to Understanding and Treating Cancer Targeting pH full in PDF, ePub and kindle. this book written by Tomas Koltai and published by Academic Press which was released on 16 January 2020 with total page 574 pages. We cannot guarantee that An Innovative Approach to Understanding and Treating Cancer Targeting pH book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity. The book discusses topics such as lactic acid and its transport system in the pH paradigm, mechanisms to decrease extra cellular pH and increase intracellular pH, NHE-1 activity in cancer, carbonic anhydrases, vacuolar ATPase proton pump, and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions, cellular acidification and extracellular alkalinization as a new and integral approach to cancer treatment. Analyzes the mechanisms that lead to the inversion of pH gradient in cancer tissues Summarizes almost 100 years of research on pH inversion in cancer in one single source, discussing the most relevant and updated researches in the field Proposes new efficient treatments against cancer using pH inversion mechanisms, either with new drugs like proton transport inhibitors and proton pump inhibitors (PTIs and PPIs) or with repurposed drugs

An Innovative Approach to Understanding and Treating Cancer Targeting pH

An Innovative Approach to Understanding and Treating Cancer  Targeting pH
  • Author : Tomas Koltai,Stephan J. Reshkin,Salvador Harguindey
  • Publisher : Academic Press
  • Release : 16 January 2020
GET THIS BOOK An Innovative Approach to Understanding and Treating Cancer Targeting pH

An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve

Prostate Cancer Metabolism

Prostate Cancer Metabolism
  • Author : Tomas Koltai,Stephan J. Reshkin,Fatima Baltazar,Larry Fliegel
  • Publisher : Academic Press
  • Release : 25 June 2021
GET THIS BOOK Prostate Cancer Metabolism

Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects – that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, standard therapies. The large body of evidence supporting these concepts makes them deserving of further research and well-designed clinical trials. It discusses lipid, cholesterol, glutamine, and glucose metabolisms and their impact

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Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 14 January 2022
GET THIS BOOK Antiangiogenic Drugs as Chemosensitizers in Cancer Therapy

Anti-angiogenic Drugs as Chemosensitizers in Cancer Therapy, Volume 19 focuses on the use of anti-angiogenic drugs as sensitizers of tumor cells to the inhibitory activity of antitumor agents. Conventional and novel anti-neoplastic agents (cytotoxic molecules, hormones/antihormones, immunotherapies) are taken into consideration, along with advances made in combination therapies. The book encompasses examples of studies on the use of antiangiogenic compounds—molecules that inhibit the growth of vessels inside a tumor—together with antineoplastic drugs in order to sensitize the resistant

Innovative Approaches for Nanobiotechnology in Healthcare Systems

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  • Author : Amna, Touseef,Hassan, M. Shamshi
  • Publisher : IGI Global
  • Release : 17 September 2021
GET THIS BOOK Innovative Approaches for Nanobiotechnology in Healthcare Systems

Innovative and fusion technologies have shown an incredible ability to improve various aspects of society, such as healthcare systems. Nanobiotechnology is one such technology that is being applied to medical equipment and treatment approaches. Many pharmaceutical and medical companies have begun to count on medical nanotechnology due to its abundant applications and practical uses. Innovative Approaches for Nanobiotechnology in Healthcare Systems is a pivotal reference source that provides insights into a comprehensive collection of novel techniques used for the development

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  • Author : Letícia Rangel
  • Publisher : BoD – Books on Demand
  • Release : 09 May 2013
GET THIS BOOK Cancer Treatment

Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer; iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5:

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  • Author : Bhushan Patwardhan,Rathnam Chaguturu
  • Publisher : Academic Press
  • Release : 03 October 2016
GET THIS BOOK Innovative Approaches in Drug Discovery

Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches.

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  • Author : Bhaskar Mazumder,Subhabrata Ray,Paulami Pal,Yashwant Pathak
  • Publisher : CRC Press
  • Release : 18 March 2019
GET THIS BOOK Nanotechnology

Today we find the applications of nanotechnology in all spheres of life. Nanotechnology: Therapeutic, Nutraceutical and Cosmetic Advances discusses recent advances in the field, particularly with therapeutics, nutraceuticals and cosmetic sciences. Therapeutics is an area which has perhaps benefitted the most, although nanoscience and technology have quietly entered the realms of food science and are playing pivotal roles in the efficient utilization of nutraceuticals. Finally, even before therapeutics came cosmetics and companies started marketing unique products embedding the beneficial and

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  • Author : Ronald B. Herberman
  • Publisher : Springer Science & Business Media
  • Release : 28 February 1986
GET THIS BOOK Cancer Immunology Innovative Approaches to Therapy

This volume is the second in the 'Cancer Treatment and Research' series focussing on basic and clinical tumor immunology. It has a rather different focus or emphasis from that of the first volume, published two years ago. That work (Basic and Clinical Tumor Immunology, R.B. Herberman, ed., Martinus Nijhoff Publishers, 1983) devoted considerable attention to up dated summaries in various areas of classical tumor immunology: specific antitumor immunity, the immunologic competence of cancer patietns, char acterization of human tumor-associated antigens,

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Receptor Tyrosine Kinases
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 June 2020
GET THIS BOOK Receptor Tyrosine Kinases

Receptor Tyrosine Kinases, Volume 147 in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research in the area of Receptor Tyrosine Kinases (RTKs) in the context of major basic science and translational advances, their importance in the development of a large number of anti-cancer drugs over the decades, and a peek into postulated advances in the coming decades for a number of RTK. Chapters in this new release are contributed by a

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  • Author : Junko Fujisaki
  • Publisher : Springer
  • Release : 06 January 2020
GET THIS BOOK Endoscopic Treatment Strategy for Upper GI Tract Neoplasms

This book presents various cases of upper GI tract neoplasms, discussing endoscopic diagnostic procedures and treatment strategies, such as white light endoscopy (WLE ), magnified endoscopy with narrow band imaging (NBI) and endoscopic ultrasonography (EUS). Focusing on the esophagus, stomach and duodenum, it provides user-friendly, practical information on these innovative approaches, and explores treatments, pathological insights, including target biopsy, and therapies for specific cases. Endoscopic Treatment Strategy for Upper GI Tract Neoplasms appeals to a wide readership, from trainees to experienced

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  • Author : Robert Gorter, M.D., Ph.D.,Erik Peper, Ph.D.
  • Publisher : North Atlantic Books
  • Release : 31 May 2011
GET THIS BOOK Fighting Cancer

Fighting Cancer describes the Gorter Model, an integrative, nontoxic approach to cancer treatment that mobilizes the immune system. It was developed by Robert Gorter, MD, PhD, who in 1976 recovered from Stage IV testicular cancer by using nontoxic treatment and no chemotherapy or radiation. Based on self-experience, extensive research, and decades of clinical practice, the treatment consists of supporting the immune system using fever therapy (hyperthermia), inoculation with immune cells, the use of the botanical mistletoe (Viscum album)—the single most

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  • Author : Renat R. Letfullin,Thomas F. George
  • Publisher : Springer
  • Release : 10 February 2017
GET THIS BOOK Computational Nanomedicine and Nanotechnology

This textbook, aimed at advanced undergraduate and graduate students, introduces the basic knowledge required for nanomedicine and nanotechnology, and emphasizes how the combined use of chemistry and light with nanoparticles can serve as treatments and therapies for cancer. This includes nanodevices, nanophototherapies, nanodrug design, and laser heating of nanoparticles and cell organelles. In addition, the book covers the emerging fields of nanophotonics and nanoplasmonics, which deal with nanoscale confinement of radiation and optical interactions on a scale much smaller than

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  • Publisher : Elsevier
  • Release : 24 June 2021
GET THIS BOOK Advanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells