American Trypanosomiasis

• Author : Kevin M. Tyler,Michael A. Miles
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

American trypanosomiasis, or Chagas disease, is caused by the protozoan parasite, Trypanosoma cruzi. Sixteen to eighteen million people are currently infected with this organism, and 45,000 deaths are attributed to the disease each year. Infection with T. cruzi is life-long, and 10-30% of persons who harbor the parasite chronically develop cardiac and gastrointestinal problems associated with the parasitosis. Although major progress has been made in recent years in reducing vector-borne and transfusion-associated transmission of T. cruzi, the burden of disability and

• Author : Jenny Telleria,Michel Tibayrenc
• Publisher : Elsevier
• Release : 18 January 2017

American Trypanosomiasis, Chagas Disease: One Hundred Years of Research, Second Edition, provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease, the host, the insect vectors, and the causative parasite. In addition, new insights on the molecular biology and diagnostics of Chagas diseases, the persistence of infections in the host, and the interaction of the parasite and host metabolism are now included in this new and

• Author : Gideon Informatics, Inc.,Stephen Berger, MD
• Publisher : GIDEON Informatics Inc
• Release : 17 March 2022

American Trypanosomiasis: Global Status is one in a series of GIDEON ebooks which explore all individual infectious diseases, drugs, vaccines, outbreaks, surveys and pathogens in every country of the world. Data are based on the GIDEON web application (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing exhaustive search of the medical literature. The ebook includes: 1. Descriptive epidemiology 2. Clinical features 3. Distribution map 4. Images 5. Global status and status in every

• Author : Jenny Telleria,Michel Tibayrenc
• Publisher : Elsevier
• Release : 03 September 2010

Chagas disease causes severe socioeconomic impact and a high medical cost in Latin America. WHO and the World Bank consider Chagas disease as the fourth most transmittable disease to have a major impact on public health in Latin America: 120 million persons are potentially exposed, 16 to 18 million of whom are presently infected, causing 45,000 to 50,000 deaths per year. It has been calculated that approximately 2.4 million potential working years are lost because of incapacity and mortality due to the disease, for an annual

• Author : María-Jesús Pinazo Delgado,Joaquim Gascón
• Publisher : Springer Nature
• Release : 20 July 2020

This book provides a comprehensive resource on various aspects of the parasite Trypanosoma cruzi and the neglected tropical disease Chagas disease (American trypanosomiasis), the disorder resulting from infection with the parasite. Topics include the biological description and taxonomy of the parasite, epidemiology and transmission routes, laboratory techniques in use when working with the parasite, as well as diagnostic measures and treatment of Chagas disease. Furthermore, a chapter with life stories of people in contact with the disease in endemic as

• Author : Matthias Perleth
• Publisher : Peter Lang Pub Incorporated
• Release : 01 January 1997

• Author : Ian Maudlin,P. H. Holmes,Michael A. Miles
• Publisher : CABI
• Release : 09 July 2004

This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and

• Author : Belkisyolé de Noya,Oscar González,Lucy J. Robertson
• Publisher : Springer
• Release : 29 October 2015

This Brief provides a comprehensive overview of Trypanosoma cruzi, a parasite that is traditionally considered as exclusively vectorborne, but can be foodborne, and may lead to outbreaks of Chagas disease in consumers. The characteristics of Trypanosoma cruzi and the clinical effects of the disease are covered, including documented outbreaks, regional patterns, and epidemiology. The various transmission routes are outlined, but with specific focus on foodborne transmission. A major emphasis of this text is contamination of fruit juices with Trypanosoma cruzi

• Author : Katherine Elliott,Maeve O'Connor,G. E. W. Wolstenholme
• Publisher : John Wiley & Sons
• Release : 16 September 2009

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

• Author : Carlos Chagas
• Publisher : Unknown
• Release : 30 May 2023

• Author : Sandra R. Wall
• Publisher : Nova Biomedical Books
• Release : 30 May 2023

The authors begin reviewing the characterization of American trypanosomiasis, or Chagas Disease, noting that although the disease has become less prevalent in recent decades, it is estimated that 8-10 million people are currently infected. Next, authors present a study wherein the dynamics of Trypanosoma cruzi infection (which causes Chagas disease) were mathematically modelled. This model assumed three clinical stages of the disease; acute, chronic indeterminate, and chronic with determinate pathology. Following this, cysteine proteases, ergosterol metabolic pathways, thiol-dependent mechanisms (trypanothione

• Author : World Health Organization
• Publisher : World Health Organization
• Release : 30 May 2023

This report provides information about new diagnostic approaches, new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease.

• Author : Jaime Marcelo Altcheh,Hector Freilij
• Publisher : Springer Nature
• Release : 09 September 2019

Chagas disease is a potentially life threatening condition that was historically mainly endemic to Latin America. Over the last decade, however, the disease has spread to and is increasingly prevalent in other continents such as North America and Europe, with an estimated 7 million people infected worldwide. It is primarily transmitted by insect vectors that carry the parasite Trypanosoma cruzi, the disease agent. In areas where there is vector control and in non-endemic countries, it is mainly transmitted via congenital infection.

• Author : Leslie Hudson
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

African and South American trypanosomiases are notable features of clinical and veterinary practice in their respective endemic areas and, as such, are of considerable economic importance. Scientifically, however, their importance ex tends beyond their clinical significance, as the trypano somes are intriguing and easily manipulated models for the study of the control of gene expression, membrane chemistry, proliferation and differentiation. It is clear from the scientific press that the rate of advance has "hotted" up in these areas of trypanosome

• Author : Anonim
• Publisher : Unknown
• Release : 30 May 1972