Oligomerization and Allosteric Modulation in G Protein Coupled Receptors

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  • Author : Anonim
  • Publisher : Academic Press
  • Pages : 488 pages
  • ISBN : 012394791X
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Oligomerization and Allosteric Modulation in G Protein Coupled Receptors

Download or Read online Oligomerization and Allosteric Modulation in G Protein Coupled Receptors full in PDF, ePub and kindle. this book written by Anonim and published by Academic Press which was released on 02 December 2012 with total page 488 pages. We cannot guarantee that Oligomerization and Allosteric Modulation in G Protein Coupled Receptors book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. In this thematic volume of Progress in Molecular Biology and Translational Science, researchers reflect on recent developments and research surrounding G protein-coupled receptors. The chapters cover a large breadth of research, including GPCR role in stem cell function and pharmacology. Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make GPCRs a crucial tool in microbiological and cancer research. Contributions from leading authorities Informs and updates on all the latest developments in the field

Oligomerization and Allosteric Modulation in G Protein Coupled Receptors

Oligomerization and Allosteric Modulation in G Protein Coupled Receptors
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 02 December 2012
GET THIS BOOK Oligomerization and Allosteric Modulation in G Protein Coupled Receptors

In this thematic volume of Progress in Molecular Biology and Translational Science, researchers reflect on recent developments and research surrounding G protein-coupled receptors. The chapters cover a large breadth of research, including GPCR role in stem cell function and pharmacology. Authors explore in-depth research techniques and applications of GPCR usage, covering theory, laboratory approaches, and unique qualities that make GPCRs a crucial tool in microbiological and cancer research. Contributions from leading authorities Informs and updates on all the latest developments

From Structure to Clinical Development Allosteric Modulation of G Protein Coupled Receptors

From Structure to Clinical Development  Allosteric Modulation of G Protein Coupled Receptors
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 13 May 2020
GET THIS BOOK From Structure to Clinical Development Allosteric Modulation of G Protein Coupled Receptors

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction,

Allosteric Receptor Modulation in Drug Targeting

Allosteric Receptor Modulation in Drug Targeting
  • Author : Norman G. Bowery
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOK Allosteric Receptor Modulation in Drug Targeting

Offering a wide array of illustrations and tables in every chapter, this book extensively covers the principles of allosterism in reference to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems-helping those new to the subject understand the importance of allosterism and providing those already working in the field with specific reference information. This title provides in-depth chapters on basic principles of allosterism and its significance at GABAA, 5HT3, nicotinic, and GABAB receptors,

Pharmacology of G Protein Coupled Receptors

Pharmacology of G Protein Coupled Receptors
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 08 September 2011
GET THIS BOOK Pharmacology of G Protein Coupled Receptors

G protein coupled receptors remain the most important class of therapeutic targets in medicine. In the last 5 years, tremendous advances have been made in our understanding of the structure and mechanism of this critical family of drug targets. The present volume explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. It explores advances in structure determination and structure-based drug design as well as new concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological

Protein Allostery in Drug Discovery

Protein Allostery in Drug Discovery
  • Author : Jian Zhang,Ruth Nussinov
  • Publisher : Springer Nature
  • Release : 09 November 2019
GET THIS BOOK Protein Allostery in Drug Discovery

The book focuses on protein allostery in drug discovery. Allosteric regulation, ʹthe second secret of lifeʹ, fine-tunes virtually most biological processes and controls physiological activities. Allostery can both cause human diseases and contribute to development of new therapeutics. Allosteric drugs exhibit unparalleled advantages compared to conventional orthosteric drugs, rendering the development of allosteric modulators as an appealing strategy to improve selectivity and pharmacodynamic properties in drug leads. The Series delineates the immense significance of protein allostery—as demonstrated by recent

GPCR Molecular Pharmacology and Drug Targeting

GPCR Molecular Pharmacology and Drug Targeting
  • Author : Annette Gilchrist
  • Publisher : John Wiley & Sons
  • Release : 10 December 2010
GET THIS BOOK GPCR Molecular Pharmacology and Drug Targeting

G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors takes a look at the way GPCRs are examined today, how they react, how their mutations lead to disease, and the many ways in which they can be screened for compounds that modulate them. Chemists, pharmacologists, and

Clinical Pharmacology for Prescribing

Clinical Pharmacology for Prescribing
  • Author : Federico Dajas-Bailador
  • Publisher : Oxford University Press, USA
  • Release : 16 September 2019
GET THIS BOOK Clinical Pharmacology for Prescribing

Clinical Pharmacology for Prescribing explains how drugs work and why they should be prescribed for common medical conditions. Linking disease processes to pharmacological interventions, this guide gives a sound basis for evidence based prescribing. Written for medical students, trainee doctors and non-medical prescribers, it addresses all aspects of practical pharmacology, explaining drug classes, their mechanisms and effects on the body. Ultimately its focus is on clinical use, so that safe prescribing decisions are based on sound understanding of science -

Allosterism in Drug Discovery

Allosterism in Drug Discovery
  • Author : Dario Doller
  • Publisher : Royal Society of Chemistry
  • Release : 24 November 2016
GET THIS BOOK Allosterism in Drug Discovery

Although the concept of allosterism has been known for over half a century, its application in drug discovery has exploded in recent years. The emergence of novel technologies that enable molecular-level ligand-receptor interactions to be studied in studied in unprecedented detail has driven this trend. This book, written by the leaders in this young research area, describes the latest developments in allosterism for drug discovery. Bringing together research in a diverse range of scientific disciplines, Allosterism in Drug Discovery is

G Protein Coupled Receptors in Drug Discovery

G Protein Coupled Receptors in Drug Discovery
  • Author : Marta Filizola
  • Publisher : Humana Press
  • Release : 21 February 2018
GET THIS BOOK G Protein Coupled Receptors in Drug Discovery

This detailed volume provides an overview of recent techniques employed in the field of G protein-coupled receptors (GPCRs) to screen for new drugs and to derive information about their receptor structure, dynamics, and function for the purpose of developing improved therapeutics. Owing to remarkable recent advances in the structural, biophysical and biochemical analyses of these receptors, as well as a growing body of evidence hinting at the possible relevance of allosteric modulators, biased agonists and oligomer-selective ligands as improved therapeutic

G Protein Coupled Receptors

G Protein Coupled Receptors
  • Author : Sandra Siehler,Graeme Milligan
  • Publisher : Cambridge University Press
  • Release : 30 September 2010
GET THIS BOOK G Protein Coupled Receptors

Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically β-adrenoceptors in cardiovascular