AGO Driven Non Coding RNAs

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  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Pages : 387 pages
  • ISBN : 0128156708
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>AGO Driven Non Coding RNAs

Download or Read online AGO Driven Non Coding RNAs full in PDF, ePub and kindle. this book written by Bibekanand Mallick and published by Academic Press which was released on 20 January 2019 with total page 387 pages. We cannot guarantee that AGO Driven Non Coding RNAs book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases. Provides a unified cutting-edge resource for both miRNAs and piRNAs, two promising AGO-clade small ncRNAs, their functions and potential applications Showcase high-throughput technologies and other approaches for discovery of these small ncRNAs and their targets Unveils the diverse molecular mechanisms by which miRNAs and piRNAs regulate gene expression in animal cells Showcase recent discoveries on involvement of Argonaute and Piwi proteins in different biological processes and diseases as well as their possible use in diagnosis Report breakthroughs in the use of small ncRNAs for diagnosis and personalized therapy

AGO Driven Non Coding RNAs

AGO Driven Non Coding RNAs
  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Release : 20 January 2019
GET THIS BOOK AGO Driven Non Coding RNAs

The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years,

Essentials of Cancer Genomic Computational Approaches and Precision Medicine

 Essentials of Cancer Genomic  Computational Approaches and Precision Medicine
  • Author : Nosheen Masood,Saima Shakil Malik
  • Publisher : Springer Nature
  • Release : 20 March 2020
GET THIS BOOK Essentials of Cancer Genomic Computational Approaches and Precision Medicine

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology

Regulatory RNAs in the Nervous System 2nd Edition

Regulatory RNAs in the Nervous System  2nd Edition
  • Author : Tommaso Pizzorusso,Alessandro Cellerino,Laure Bally-Cuif
  • Publisher : Frontiers Media SA
  • Release : 13 November 2018
GET THIS BOOK Regulatory RNAs in the Nervous System 2nd Edition

Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these non-coding RNAs (nc-RNAs) can regulate gene expression. Almost on weekly basis, new findings reveal the regulatory role of nc-RNAs exert in many biological processes. Overall, these studies are making increasingly clear that, both in model organisms and in humans, complexity is not a function of the

Micro RNAs in Cancer

Micro RNAs in Cancer
  • Author : Feng Yu
  • Publisher : Unknown
  • Release : 15 June 2021
GET THIS BOOK Micro RNAs in Cancer

Non-coding RNAs have become a hot topic of cancer research in recent decades, with miRNAs being probably the most active area of research. However, the functions of short non-coding RNA (ncRNA) fragments commonly existing in cells remains less understood. Herein we explore the novel ncRNAs which play a role in cancer progression. The first part of the thesis focuses on miRNAs processed from novel sources that have a role in p53 regulation. p53 is a master tumour repressor that participates

Cortical Development

Cortical Development
  • Author : Novartis Foundation
  • Publisher : Wiley-Interscience
  • Release : 15 June 2021
GET THIS BOOK Cortical Development

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system. Chapters in this book deal specifically with cell fate determination, cell migration and disorders of cell migration; current concepts and new ideas about cortical arealisation, and disorders which can arise

Control and Regulation of Transport Phenomena in the Cardiac System Volume 1123

Control and Regulation of Transport Phenomena in the Cardiac System  Volume 1123
  • Author : Samuel Sideman,Rafael Beyar,Amir Landesberg
  • Publisher : Wiley-Blackwell
  • Release : 14 April 2008
GET THIS BOOK Control and Regulation of Transport Phenomena in the Cardiac System Volume 1123

Leading researchers in the life sciences and engineers involved in research of transport phenomena in biological systems have contributed chapters that identify, analyze, and modify the control and regulation mechanisms of transport phenomena in biological systems, with particular emphasis on the cardiac system. Included in the contributions to this volume are the following topics: signaling mechanisms and transport phenomena; blood-tissue exchange and inter-tissue transport; cellular membrane transport and endocytosis of ions and metabolites; intracellular transport, energetics, and molecular motors; system

Molecular Neuropharmacology A Foundation for Clinical Neuroscience Fourth Edition

Molecular Neuropharmacology  A Foundation for Clinical Neuroscience  Fourth Edition
  • Author : Eric J. Nestler,Steven E. Hyman,Robert C. Malenka
  • Publisher : McGraw Hill Professional
  • Release : 05 September 2020
GET THIS BOOK Molecular Neuropharmacology A Foundation for Clinical Neuroscience Fourth Edition

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The definitive guide to treating neurologic and psychiatric disorders with drugs and other approaches Fully updated with the latest research and drugs, Nestler, Hyman, & Malenka’s Molecular Neuropharmacology, Fourth Edition, is the leading guide to molecular neuroscience. Providing an in-depth look at the neuropharmacological fundamentals of the nervous system, it delivers the knowledge

Human Molecular Genetics

Human Molecular Genetics
  • Author : Tom Strachan,Andrew Read
  • Publisher : Garland Science
  • Release : 29 March 2018
GET THIS BOOK Human Molecular Genetics

Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject. The text has been

Immunoinformatics

Immunoinformatics
  • Author : Novartis,Novartis Foundation Symposium
  • Publisher : John Wiley & Sons
  • Release : 21 November 2003
GET THIS BOOK Immunoinformatics

Encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunilogical experimentation and immuogenomics.

Regulation of Virulence in the Plant Pathogen Pseudomonas Syringae Pv Tomato DC3000

Regulation of Virulence in the Plant Pathogen Pseudomonas Syringae Pv  Tomato DC3000
  • Author : Hanh Ngoc Lam
  • Publisher : Unknown
  • Release : 15 June 2021
GET THIS BOOK Regulation of Virulence in the Plant Pathogen Pseudomonas Syringae Pv Tomato DC3000

The type III secretion system (T3SS) is required for virulence of the gram-negative plant pathogen Pseudomonas syringae pv. tomato DC3000 (DC3000) in tomato and Arabidopsis. The alternative sigma factor HrpL directly regulates expression of T3SS genes by binding to a short DNA sequence designated as the "hrp promoter". The ability of DC3000 to colonize plants, subdue multiple layers of plant defense and multiply in plant tissues relies on the activities carried out by the many T3SS regulon