Adverse Events and Oncotargeted Kinase Inhibitors

Produk Detail:
  • Author : Giuseppe Tridente
  • Publisher : Academic Press
  • Pages : 736 pages
  • ISBN : 0128094451
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Adverse Events and Oncotargeted Kinase Inhibitors

Download or Read online Adverse Events and Oncotargeted Kinase Inhibitors full in PDF, ePub and kindle. this book written by Giuseppe Tridente and published by Academic Press which was released on 08 May 2017 with total page 736 pages. We cannot guarantee that Adverse Events and Oncotargeted Kinase Inhibitors book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug’s development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement. This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events. Offers a unique and comprehensive publication on the adverse events associated with a new and fast-growing class of medicines Provides a systematic analysis of adverse events aimed at better prevention through understanding and offering insights for the development of safer drugs Uses practical guidelines to establish a leading reference on this class of drugs for educators, researchers, drug developers, clinicians, safety professionals, and more

Adverse Events and Oncotargeted Kinase Inhibitors

Adverse Events and Oncotargeted Kinase Inhibitors
  • Author : Giuseppe Tridente
  • Publisher : Academic Press
  • Release : 08 May 2017
GET THIS BOOK Adverse Events and Oncotargeted Kinase Inhibitors

Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug’s development and submission is provided, along with a more detailed analysis of the mechanism(s)

Immunotherapy for Gastrointestinal Malignancies

Immunotherapy for Gastrointestinal Malignancies
  • Author : Ramakrishna Vadde,Ganji Purnachandra Nagaraju
  • Publisher : Springer Nature
  • Release : 31 January 2021
GET THIS BOOK Immunotherapy for Gastrointestinal Malignancies

This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers. It also discusses the current challenges of using immunotherapy for the treatment of gastrointestinal malignancies. The book reviews highly sensitive and specific immunomarkers for the detection of GI malignancies, and examines therapeutic vaccines and the major cytokines involved in GI immunotherapy, as well as their basic biology and

Targeted Therapies for Lung Cancer

Targeted Therapies for Lung Cancer
  • Author : Ravi Salgia
  • Publisher : Springer
  • Release : 26 June 2019
GET THIS BOOK Targeted Therapies for Lung Cancer

This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer. It is now well established that there is tremendous heterogeneity among cancer cells both at the inter- and intra-tumoral level. Further, a growing body of work highlights the importance of targeted therapies and personalized medicine in treating cancer patients. In contrast to conventional therapies that are typically administered to the average patient regardless of the patient’s

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 21 November 2018
GET THIS BOOK Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic,

Side Effects of Drugs Annual

Side Effects of Drugs Annual
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 31 October 2018
GET THIS BOOK Side Effects of Drugs Annual

Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 40, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a reliable and critical survey of new data and trends in the area of adverse drug reactions and interactions, with an international team of specialists contributing each year. Topics covered in this release include Central Nervous System Stimulants

Protein Kinases

Protein Kinases
  • Author : Anonim
  • Publisher : BoD – Books on Demand
  • Release : 08 December 2021
GET THIS BOOK Protein Kinases

For the past two decades, the protein kinase family has been an intense area of research for developing anticancer drugs. Despite tremendous advancements in kinase drug expansion, many kinases are still unexplored. As such, this book includes research and review articles from experts that focus on protein kinase signalling pathways as a molecular drug target. Chapters include illustrations and cover such topics as the mechanism of action and anticancer activity of protein kinase inhibitors on various cancer types. They also

Role of Tyrosine Kinases in Gastrointestinal Malignancies

Role of Tyrosine Kinases in Gastrointestinal Malignancies
  • Author : Ganji Purnachandra Nagaraju
  • Publisher : Springer
  • Release : 27 September 2018
GET THIS BOOK Role of Tyrosine Kinases in Gastrointestinal Malignancies

The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy.

An Innovative Approach to Understanding and Treating Cancer Targeting pH

An Innovative Approach to Understanding and Treating Cancer  Targeting pH
  • Author : Tomas Koltai,Stephan J. Reshkin,Salvador Harguindey
  • Publisher : Academic Press
  • Release : 16 January 2020
GET THIS BOOK An Innovative Approach to Understanding and Treating Cancer Targeting pH

An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve

Infections Related to Biologics An Issue of Infectious Disease Clinics of North America

Infections Related to Biologics An Issue of Infectious Disease Clinics of North America
  • Author : Aruna K. Subramanian,Dora Ho
  • Publisher : Elsevier Health Sciences
  • Release : 04 June 2020
GET THIS BOOK Infections Related to Biologics An Issue of Infectious Disease Clinics of North America

In collaboration with Consulting Editor Dr. Helen Boucher, Drs. Aruna Subramanian and Dora Yuk-Wai Ho have created an extremely timely and relevant issue for infectious disease physcians, as the field of biologics is exploding. These new agents are being used in rheumatologic diseases, hematologic malignancies, solid tumors, and other conditions; there is a lack of guidance in the literature on how to address their infectious risks. The first 9 articles explain the mechanisms of action of the biologic agents and the

Orbit and Oculoplastics

Orbit and Oculoplastics
  • Author : Adit Gupta,Prerana Tahiliani
  • Publisher : Springer Nature
  • Release : 26 November 2019
GET THIS BOOK Orbit and Oculoplastics

This book covers the advances in the field of ophthalmic plastic and orbital surgery. This book aims at educating the general and specialist ophthalmologists and residents about the various facets that this niche subspecialty has to offer in the future. It covers the latest evidence-based approach in the diagnosis and management of various oculoplastic disorders. Chapters are supplemented with ample illustrations and well labelled diagrams wherever necessary. Chapters include key topics such as imaging, orbital decompression, lacrimal surgery, and orbital

Small Molecules in Hematology

Small Molecules in Hematology
  • Author : Uwe M. Martens
  • Publisher : Springer
  • Release : 01 August 2018
GET THIS BOOK Small Molecules in Hematology

This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed. Extensive research into the molecular mechanisms

Renal Pharmacotherapy

Renal Pharmacotherapy
  • Author : Larry K. Golightly,Isaac Teitelbaum,Bonita A. Simendinger,Tyree H. Kiser,Gerard R. Barber,Nancy M. Stolpman
  • Publisher : Springer Nature
  • Release : 16 May 2022
GET THIS BOOK Renal Pharmacotherapy

To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function. Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications. This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has

Triple negative Breast Cancer

Triple negative Breast Cancer
  • Author : Xiyun Deng,Faqing Tang,Thomas J Rosol
  • Publisher : World Scientific
  • Release : 29 October 2020
GET THIS BOOK Triple negative Breast Cancer

Triple-negative breast cancer (TNBC) represents a challenge clinically due to the lack of actionable targets coupled with an aggressive disease course and a worse prognosis compared to other breast cancer subtypes. This book covers aspects of TNBC ranging from epidemiology, biology, molecular classification, to currently available and potentially new therapeutic options for TNBC. This book contains a range of recommended resources, including recent reviews, schematic illustrations, and information for patients with TNBC. Individuals including researchers and educators, practitioners, pharmaceutical professionals,