Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

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  • Author : Surendra Nimesh
  • Publisher : Woodhead Publishing
  • Pages : 256 pages
  • ISBN : 0081005636
  • Rating : /5 from reviews
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Download or Read online Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids full in PDF, ePub and kindle. this book written by Surendra Nimesh and published by Woodhead Publishing which was released on 04 April 2017 with total page 256 pages. We cannot guarantee that Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc. Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc. Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids
  • Author : Surendra Nimesh,Ramesh Chandra,Nidhi Gupta
  • Publisher : Woodhead Publishing
  • Release : 04 April 2017
GET THIS BOOK Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles

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GET THIS BOOK Nucleic Acids as Gene Anticancer Drug Delivery Therapy

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GET THIS BOOK Nano Oncologicals

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  • Release : 19 October 2012
GET THIS BOOK RNA Interference from Biology to Therapeutics

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  • Publisher : John Wiley & Sons
  • Release : 28 September 2007
GET THIS BOOK Biomedical Applications of Nanotechnology

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  • Publisher : Academic Press
  • Release : 18 November 2014
GET THIS BOOK Nonviral Vectors for Gene Therapy

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  • Publisher : DIANE Publishing
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GET THIS BOOK Functional Nucleic Acid incorporated Nanomaterials for Bioanalytical and Biomedical Applications

Advances in nanotechnology and biotechnology are creating novel tools for various bioanalytical and biomedical applications. Through rational engineering, nanomaterials can be tailored in a predictable manner to meet the needs of specific applications. In addition, by coupling with biomolecules (e.g., nucleic acids), nanomaterials can possess molecular recognition capability. Therefore, the objective of this research is to develop functional nucleic acid-incorporated nanomaterials for early disease diagnosis, targeted drug delivery, and effective cancer therapy. First, we constructed a smart multifunctional nanostructure (

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  • Release : 09 March 2016
GET THIS BOOK Drug Delivery

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This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised