Advances in Mitochondrial Medicine

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  • Author : Roberto Scatena
  • Publisher : Springer
  • Pages : 461 pages
  • ISBN : 9789402405880
  • Rating : /5 from reviews
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Download or Read online Advances in Mitochondrial Medicine full in PDF, ePub and kindle. this book written by Roberto Scatena and published by Springer which was released on 23 August 2016 with total page 461 pages. We cannot guarantee that Advances in Mitochondrial Medicine book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are actually a growing number of studies which assign a significant pathogenic role to damaged mitochondria in different diseases: ischemia/reperfusion injury, neurodegenerative diseases, cancer with its dramatic sequelae (i.e, metastasis), metabolic syndrome, hyperlipidemias, just to mention a few of the most important pathologies. In this context, a further aspect that should not be disregarded is the interaction of pharmacological agents with mitochondria, not only in regard of the toxicological aspects but, above all, of the potential therapeutic applications. In fact, it is interesting to note that, while the properties of different so-called “mitoxicants” are well-known, the subtle linkages between drugs and mitochondria is still in need of a real pharmacological and therapeutic control at the clinical level. This lack of consideration can often lead to an underestimation of unwanted toxic effects but also of desirable therapeutic activities. A reevaluation of the potential clinical role of mitochondria could give a new light on some yet obscure aspects of human pathophysiology.

Advances in Mitochondrial Medicine

Advances in Mitochondrial Medicine
  • Author : Roberto Scatena,Patrizia Bottoni,Bruno Giardina
  • Publisher : Springer
  • Release : 23 August 2016
GET THIS BOOK Advances in Mitochondrial Medicine

Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include

Advances in Mitochondrial Medicine

Advances in Mitochondrial Medicine
  • Author : Roberto Scatena,Patrizia Bottoni,Bruno Giardina
  • Publisher : Springer Science & Business Media
  • Release : 09 February 2012
GET THIS BOOK Advances in Mitochondrial Medicine

Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include

Advances in Mitochondrial Medicine

Advances in Mitochondrial Medicine
  • Author : Roberto Scatena,Patrizia Bottoni,Bruno Giardina
  • Publisher : Springer Science & Business Media
  • Release : 08 March 2012
GET THIS BOOK Advances in Mitochondrial Medicine

Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include

Mitochondria and Their Role in Cardiovascular Disease

Mitochondria and Their Role in Cardiovascular Disease
  • Author : José Marín-García
  • Publisher : Springer Science & Business Media
  • Release : 19 November 2012
GET THIS BOOK Mitochondria and Their Role in Cardiovascular Disease

Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in

Advances in Mitochondria Research and Application 2012 Edition

Advances in Mitochondria Research and Application  2012 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release : 26 December 2012
GET THIS BOOK Advances in Mitochondria Research and Application 2012 Edition

Advances in Mitochondria Research and Application / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Mitochondria in a compact format. The editors have built Advances in Mitochondria Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mitochondria in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Mitochondria Research and Application / 2012

Mitochondria and Their Role in Cardiovascular Disease

Mitochondria and Their Role in Cardiovascular Disease
  • Author : José Marín-García
  • Publisher : Springer
  • Release : 17 November 2012
GET THIS BOOK Mitochondria and Their Role in Cardiovascular Disease

Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in

The Rise of Mitochondria in Medicine

The Rise of Mitochondria in Medicine
  • Author : Loredana Moro
  • Publisher : Unknown
  • Release : 04 September 2020
GET THIS BOOK The Rise of Mitochondria in Medicine

Mitochondria are critical bioenergetic and biosynthetic machines that are essential for normal cell function. Traditionally, mitochondria have been considered the powerhouse of the cell, as they supply most of the cellular energy through oxidative phosphorylation. In addition, they supply the building blocks needed for the synthesis of cellular biomass. More recently, mitochondria have been recognized as signaling hubs that receive and transmit signals throughout the cell, thereby affecting cell functionality and fate. The signals generated by mitochondria include changes in

Mitochondrial Dysfunction in Neurodegenerative Disorders

Mitochondrial Dysfunction in Neurodegenerative Disorders
  • Author : Amy K. Reeve,Eve M. Simcox,Michael R. Duchen,Doug M. Turnbull
  • Publisher : Springer
  • Release : 08 June 2016
GET THIS BOOK Mitochondrial Dysfunction in Neurodegenerative Disorders

This second edition brings together up-to-date contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The reader is guided through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, and on to the consequences of this dysfunction for neuronal function before finishing with the modelling of these disorders and discussion of new potential

Mitochondria

Mitochondria
  • Author : Stephen W. Schaffer,M. Saadeh Suleiman
  • Publisher : Springer Science & Business Media
  • Release : 24 February 2010
GET THIS BOOK Mitochondria

This book is indispensable to researchers in fields as diverse as Molecular Biology and Biophysics. It covers the important role that mitochondria play in a variety of biochemical spheres. It analyses how mitochondria affect metabolic pathways, how they are active in the regulation of cytosolic constituents, and their role in initiating signal pathways. Also covered are the way mitochondria help to regulate apoptosis, and how they modulate cellular hypertrophy and proliferation. It gives an overview of the emergence of mitochondria

Horizons in Medicine 18

Horizons in Medicine 18
  • Author : Jonathan M. Rhodes
  • Publisher : Royal College of Physicians
  • Release : 30 July 2021
GET THIS BOOK Horizons in Medicine 18

The papers included in this volume provide a fascinating review of contemporary pathology, diagnostic techniques, management approaches and pharmacological interventions. They are based on the popular Advanced Medicine conference organised annually by the Royal College of Physicians which aims to present 'the latest cutting edge advances in clinical medicine, supported by improved understanding of disease mechanisms'. Each chapter, by an eminent physician from one of a variety of specialties included, is followed by self-assessment questions, which allow the reader to

The Human Mitochondrial Genome

The Human Mitochondrial Genome
  • Author : Giuseppe Gasparre,Anna Maria Porcelli
  • Publisher : Academic Press
  • Release : 19 August 2020
GET THIS BOOK The Human Mitochondrial Genome

The Human Mitochondrial Genome: From Basic Biology to Disease offers a comprehensive, up-to-date examination of human mitochondrial genomics, connecting basic research to translational medicine across a range of disease types. Here, international experts discuss the essential biology of human mitochondrial DNA (mtDNA), including its maintenance, repair, segregation, and heredity. Furthermore, mtDNA evolution and exploitation, mutations, methods, and models for functional studies of mtDNA are dealt with. Disease discussion is accompanied by approaches for treatment strategies, with disease areas discussed including

Advances in DNA Repair

Advances in DNA Repair
  • Author : Clark Chen
  • Publisher : BoD – Books on Demand
  • Release : 18 November 2015
GET THIS BOOK Advances in DNA Repair

This book edition is intended to provide a concise summary for select topics in DNA repair, a field that is ever-expanding in complexity and biologic significance. The topics reviewed ranged from fundamental mechanisms of DNA repair to the interface between DNA repair and a spectrum on cellular process to the clinical relevance of DNA repair in oncologic paradigms. The information in this text should provide a foundation from which one can explore the various topics in depth. The book serve

Advances in Research on Down Syndrome

Advances in Research on Down Syndrome
  • Author : Subrata Dey
  • Publisher : BoD – Books on Demand
  • Release : 31 January 2018
GET THIS BOOK Advances in Research on Down Syndrome

This book provides a concise yet comprehensive source of current information on Down syndrome. It focuses on exciting areas of research on chromosome editing, neurogenomics and diseases associated with Down syndrome. Research workers, scientists, medical graduates and physicians will find this book as an excellent source for consultation and references. Key features of this book are chromosome engineering in Down syndrome, mental retardation and cognitive disability, prenatal diagnosis and diseases associated with Down syndrome. Although aimed primarily for research workers